History HalfHumanHybrid / AnimeAndManga

* ''Manhua/RetiredHeroes'': Tifa is half demon, which occasionally gets her glares in the village. However, the fact that her demon mother is one of the town heroes (albeit a surly one) means it doesn't get too bad.

-->-- '''Kagome''', ''Anime/{{Inuyasha}}''

** The original Zentraedi/Human hybrid from ''Anime/SuperDimensionFortressMacross'' was baby Komillia ("little Millia", after one of her mother's [[SpellMyNameWithAnS various romanized name spellings]]).
** In ''Anime/{{Macross 7}}'', we meet Mylene, the series's GenkiGirl, who is naturally also a hybrid (Komillia's little sister, at that). In fact, when the heroes discover an ancient ([[RagnarokProofing yet remarkably still functional]]) ruin, it's Mylene's hybrid nature that unlocks the final chamber, allowing the ruin's computer to see that the different races had stopped fighting and had children together.

*** Official material has confirmed that Mylene actually has four MORE sisters never seen in the series. Max and Millia apparently REALLY hit it off.

* Anime/NeonGenesisEvangelion has [[spoiler:Ayanami Rei]], who is part human and part [[spoiler:Angel]].

** Sylphiette is a quarter eleven. Her father was half-elf and her mother was a human. Well, [[ALittleBitBeastly not entirely human]], which is why Sylphiette isn't a pure quarter elf. In the finale, she also has children with Rudeus, who are one-eighth elven.

* ''LightNovel/GrimoireOfZero'': The beast souls look like humanoid animals. And though some of them are transformed by magic, most of them are born that way. Their parents are both humans, yet they are expressly considered a mixture of humans and animals.

* In ''Anime/{{Endride}}'', Louise is half-[[BeastMan Zoozian]], and although she has been able to pass as fully human because of her appearance, she grew up facing the discrimination and censure that was brought upon her [[MalignedMixedMarriage parents]] due to Fantastic Racism.

* In ''Anime/EurekaSevenAO'', the protagonist Ao is a half human and half Coralian hybrid. Later on it's revealed [[spoiler:[[ThereIsAnother he may not be the only one...]] though the truth is still pretty ambiguous.]]

* In ''Literature/TheFamiliarOfZero'', Tiffania had a human father and an elf mother. Other than inheriting the PowerOfTheVoid and giant boobs from her father's bloodline (both of these traits are unusual in an elf), she looks just like any other elf.
* In ''Manga/FullmetalAlchemist'', [[spoiler:one minor villain, Tucker, creates a "chimera" -- that is, a creature that is a fusion of two creatures of different species -- by using alchemy to fuse his five-year-old daughter, [[TheCutie Nina]], with her dog, Alexander. The result is pathetic creature that lives in constant pain and can barely talk, though still loves its "father". Eventually, Scar comes across Tucker and the [[KillTheCutie chimera]] and kills them both.]]

* In the anime ''Anime/GallForce'', the Hybrid between the all-female Solonoids and the monstrous Paranoids turned out to be a human male. The ''[[AdamAndEvePlot first one]]'', at that.
* In ''Manga/GreenWorldz'', there are humans with different forms and abilities that are hunting humans down for reasons of their own. They are literally just refered to as "Hybrid humans". Few info is known about them except they are [[FromASingleCell near impossible to kill through conventional means]] and [[RunOrDie avoiding them would be a priority for survival]]. Even badass Iwatobi who [[spoiler:time traveled from 30 years of the future]] could not come up with easy tips to deal with them.
* ''LightNovel/GrimoireOfZero'' has the beast souls. They look like humanoid animals. And though some of them are transformed by magic, most of them are born that way. Their parents are both humans, yet they are expressly considered a mixture of humans and animals.

* In ''LightNovel/TheFamiliarOfZero'', Tiffania had a human father and an elf mother. Other than inheriting the PowerOfTheVoid and giant boobs from her father's bloodline (both of these traits are unusual in an elf), she looks just like any other elf.

* Nao from ''Manga/BloodyCross'' is half human, half angel. [[spoiler:Tsukimiya and Hinata are both angelic {{Dhampyr}}s, being the children of vampires and angels, but with Tsukimiya, this mix of holy and unholy is killing her, while with Hinata, his soul is the angelic part of him]].

* Nao from ''Manga/BloodyCross'' is half human, half angel.

* Yuu Mishouzaki's [[Manga/TheLegendOfZelda Zelda manga]] was created back when we knew very little about Hyrule or Zelda lore. As such the concept of Hyrulians wasn't really a thing so the manga had them as "elves". The elves are [[FantasticRacism discriminated against]] but the Queen had a romance with an elf. Link is the child born from said romance.

* In ''LightNovel/TheFamiliarOfZero'', Tiffania had a human father and an elf mother. Other than inheriting the PowerOfTheVoid and GagBoobs from her father's bloodline (both of these traits are unusual in an elf), she looks just like any other elf.

* Akihito in ''LightNovel/BeyondTheBoundary'' is half-demon, half-human, which makes him have NighInvulnerability as his wounds always heal despite the damage he gets.

* Eina in ''LightNovel/IsItWrongToTryToPickUpGirlsInADungeon'' is a human-elf hybrid. However, her example is far more mundane than most examples here--while other elf characters in this universe are badasses in different ways, she's an OfficeLady without special powers.

* Emilia from ''LightNovel/ReZero'' is a half-elf with [[MysticalWhiteHair silver hair]]. Although her parents are rarely mentioned, it is made clear that her father was an [[OurElvesAreDifferent elf]] and her mother was a human.

* ''LightNovel/ShakuganNoShana'' has Justus. His father was a human, and his mother was a [[OurDemonsAreDifferent mighty demon]].

* ''LightNovel/{{Slayers}}'' has Zelgadis, an artificial example of this trope. He was born pure human, but was merged with a Blow Demon (a kind of Astral Goblin) and a stone {{Golem}} through the magic of Rezo, the Red Priest. This gives him pointed ears, blue skin, purple/lavender hair, patches of pebble-like "growths" all over his body, and either skin or flesh of solid rock.
* ''LightNovel/SoICantPlayH'': At first, Ryouske's run-in [[{{Shinigami}} with Lisara]] seems like a chance encounter. But, in Episode 8, his mother recounts having met Ryosuke's father under the exact same circumstances, with heavy implications that he was [[SpiritWorld from Grimwald]], the same as Lisara. Since his mother became pregnant with Ryosuke as a result of sleeping with his father, it'd mean he's half human and half shinigami.
* In ''LightNovel/SoImASpiderSoWhat'' Humans can conceivably have children with both Demons and Elves, though this is extremely rare due to the ForeverWar and extreme isolationism, respectively. The reason this is possible is that [[spoiler:Demons and Elves are just sub-species of Humans created by forced "evolution" using MA energy]].

* Ai, the protagonist of ''LightNovel/SundayWithoutGod'', is half-human, half-gravekeeper (humanoid beings who can grant true death to people). Unlike other gravekeepers, she has emotions and can't sense the presence of [[TheUndead the deceased]], but she can still bury them just as well.

* The LightNovel ''LightNovel/{{Vamp}}!'' features a [[{{Dhampyr}} half-vampire]], Watt, who is impervious to sunlight but is said to never be able to reach the same level of power as regular vampires.

* At the end of the manga of ''LightNovel/SpiceAndWolf'', the wolf goddess Horo from the human Lawrence is pregnant.

** Inuyasha is half-dog-{{youkai}} and has a mixture of dog and human traits. He's mostly human in appearance ([[LittleBitBeastly aside from his gray hair and dog ears]]), but has supernatural powers, dog fangs, SupernaturalGoldEyes, claws, and a hyperacute sense of hearing and smell. His abilities are inferior to his full-blooded [[UpToEleven daiyoukai]] brother's, but having a daiyoukai father means he's much stronger than powerful, but ordinary, youkai. One night a month he's forced to [[BroughtDownToNormal transform into a human]], and if his life is in grave danger a SuperPoweredEvilSide takes over where his youkai blood takes control of his mind and body.

* The heroine Chisaya from ''Manga/OnikirisamaNoHakoirimusume'' is half-human and half-yokai, with a giant {{Kitsune}} as a mother.

* ''Manga/SazanEyes'': Koko and his family come from a line of half-human half-demons, though they're mostly human-looking and have little magic powers on their own. Secondary character Yoriko had an half-demon father, from whom she inherited her thought projection powers.

* Seriously handled in ''Anime/BagiTheMonsterOfMightyNature'': Bagi is a human/cougar hybrid created in a lab (although she has pink fur). She's somewhat rare in being pretty much human behaviorally as well. She also has psychic powers of hypnosis. [[spoiler:Then without any explanation, at the end of the plot, she inexplicably loses her intelligence and ability to speak and even stops being bipedal.]]

* In a {{cyberpunk}}, non-DNA variant, ''Anime/GhostInTheShell1995'' ends with Kusanagi [[MentalFusion merging with the Puppet Master's formless entity]] to become something else entirely.

* ''Manga/InuYasha'':

* In ''Anime/WickedCity'', [[spoiler:the human Renzaburou and the demon Makie not only become a BattleCouple, but conceive a child. This is actually a part of a BatmanGambit by their boss Giuseppe: theirs is the ''first'' half-human, half-demon kid, and his/her existence will be the living proof that humans and demons can live in peace.]]

* There's a strange version in ''Manga/ElfenLied''. All Diclonii, drones included, can infect humans with a virus that causes all future offspring to be Diclonii drones, incapable of reproducing sexually. These drones are also always female. However, there is one Diclonius, the queen, who can reproduce sexually, and if her mate were human, her offspring would probably be some kind of Half-Human Hybrid. There are a bunch of powerless male half-human Diclonii wandering around, probably a result of something of that nature happening up in the family tree.\\
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In the manga version, the male Diclonii are revealed to be [[spoiler:descended from a family of humans who merely have a weird skull defect.]]

** Some half-youkais are not born as such, but were originally humans who are voluntarily merged with "lesser youkais". The BigBad Naraku has arisen in this way, and in the anime, we see that even with the dark priestess Tsubaki and the princess Sara Asano.

* In the manga/anime ''Manga/{{Claymore}}'', the heroes are a sect of all female half-human, half-''youma'' who hunt full ''youma'', although [[spoiler:the main heroine Clare is actually only a quarter youma]]. A fallen Claymore warrior is called an "Awakened One" and is far ''more'' powerful than a pure-blooded ''youma''.\\

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A Claymore warrior is somewhat different from other hybrids in that they are born human and become half-''youma'' by [[spoiler:having ''youma'' flesh implanted into their body. Claire is a quarter ''youma'' because she requested to have a certain Claymore's flesh used instead]]. This turns out to be a critical plot point because [[spoiler:quarter-''youma'' are physically weaker but have a far greater degree of control over their abilities and are more likely to survive PowerIncontinence]].

** Some half-youkais are not born as such, but were originally humans who are voluntarily merged with "lesser youkais". The BigBad Naraku has arisen in this way, and in the anime, we see that even with the dark priestess Tsubaki and the princess Sara Asano.

* Kaira from ''Anime/YokaiWatchShadowsideTheReturnOfTheOniKing'' is a human/yokai hybrid. He looks like a human, except for his [[YouGottaHaveBlueHair blue hair]] and TechnicolorEyes, and he is treated like a yokai. Kaira believes he's hated by yokai due to HalfBreedDiscrimination, but Enma believes it's because of his dark side.

* ''Anime/IlSolePenetraLeIllusioni'' has a spoilerific example. [[spoiler:Akari's father was possessed by a Daemonia at the time of her conception, making her half-human, half-Daemonia, and this is why she can hear Daemonia's voices. Cerebrum also intends to use her to create a new breed of Daemonia.]]

* In a cyberpunk, non-DNA variant, the original ''Anime/GhostInTheShell'' movie ended with Kusanagi merging with the Puppet Master's formless entity to become something else entirely.

** Some half-youkais are not born as such, but were originally humans who are voluntarily merged with "lesser youkais". The {{Big Bad}} Naraku has arisen in this way, and in the anime, we see that even with the dark priestess Tsubaki and the princess Sara Asano.