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* Many of the female characters created by Edgar Allen Poe fit this type. Notable examples include the eponymous heroines of his short stories "Ligeia" and "Berenice", and his famous poem "Annabel Lee". [[spoiler: They always die.]]
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* Many of the female characters created by Edgar Allen Poe fit this type. Notable examples include the eponymous heroines of his short stories "Ligeia" and "Berenice", "Literature/{{Berenice}}", and his famous poem "Annabel Lee". [[spoiler: They always die.]]
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* ''Literature/TheFallOfTheHouseOfUsher'': Madeline is a typical ill and dying Poe woman, similar to those in many of his other stories, but in this one her brother Roderick is also sickly and weak.
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* Smike in ''[[Creator/CharlesDickens Nicholas Nickleby]]'' eventually dies of tuberculosis, although the disease is never explicitly named.
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* Smike in ''[[Creator/CharlesDickens Nicholas Nickleby]]'' ''Literature/NicholasNickleby'' eventually dies of tuberculosis, although the disease is never explicitly named.
* In ''Literature/SweetPiglet'', we have the Master, who dies of an unnamed terminal illness.
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* In ''Literature/SweetPiglet'', we have the Master, who dies of an unnamed terminal illness
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* In ''Literature/SweetPiglet'', we have [[spoiler:The "Sleeping Knights" guild]] in ''Literature/SwordArtOnline'' [[spoiler:is made up entirely of terminally ill players logged into the Master, who dies of an unnamed terminal illnessgame via a special medical device calls the "Medicuboid". Yuuki (mentioned above under "Female examples") suffers from AIDS, while another member, Siune, has leukemia]].
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* Victor Frankenstein from ''Literature/{{Frankenstein}}'': A combination of neglecting food and rest to create the Creature and the shock of seeing it alive causes Victor to develop a fever that would have killed him if not for Henry. The ensuing TraumaCongaLine of the rest of the book worsens Victor’s health to the point of frequent fevers and a two month coma, escalating in him [[spoiler: dying from illness and despair.]]
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* ''Literature/FullMetalPanic'': Kurz Weber is stated to have joined Mithril in order to pay the hospital bills of a young girl who was critically injured in a mission he was involved in. [[spoiler:More exactly, during the assassination of the man responsible for the deaths of Kurz's parents. Kurz, who was supposed to take the shot, stopped when he realized that the poor girl would also be hit; his ColdSniper mentor, Wilhelm Casper, had fewer scruples and fired anyhow]].
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* ''Literature/{{Moshidora}}'': Yuki Miyata's illness is not specified, aside of being a congenital one; her hospitalization requires her best friend Minami to take her place as the local CuteSportsClubManager. [[spoiler: Unfortunately, Yuki does NOT get better, and Minami suffers an HeroicBSOD when she dies.]]
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* ''Literature/SwordArtOnline'': [[spoiler:Yuuki Konno contracted AIDS when she was born. By the time she was introduced in ''Mother's Rosario'', she was already blind, bedridden and on the verge of death in the real world.]]
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* Three male characters in ''Literature/{{Another}}'' have this. Our protagonist Kouichi Sakakibara has pneumothorax ([[http://en.wikipedia.org/wiki/Pneumothorax collapsed lung]]),[[spoiler:and he's hospitalized due to it for almost a month at the start of the story, making him miss his first day at [[NewTransferStudent his new school]] and thus missing several details about what will go on]]; Ikuo Takabayashi has [[HeartTrauma a heart condition]] [[spoiler:[[KilledOffForReal and it takes away his life]]]], and Daisuke Wakui is asthmatic.
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* Suzu's best friend Seishuu in ''Literature/TheTwelveKingdoms'' got a head injury as a little child, in the same incident with monsters that got his mother killed. As a consequence, he sustained brain damage and suffers constant headaches. [[spoiler: He later [[HeroicRROD goes blind as a side-effect]], which gets him killed when [[LookBothWays he cannot see a carriage going towards him and gets hit point-blank]].]]
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* In ''Literature/TheTwelveKingdoms'', the holy beasts named ''kirin'' choose [[FisherKing each of the rulers]] for the realms. If said king or queen doesn't do well and the land suffers, they get struck with a fatal illness named ''shitsudou'', manifesting itself via FacialMarkings and physical weakness that quickly kills them. Only the full redemption (which has never happened) or the RedemptionEqualsDeath ([[spoiler: Joukaku of Kei and Shishou of Sai]]) of the sovereign can save them from death. Kirins of ''both'' genders (Hourin, Kourin and Sairin are females; Keiki is male) have gotten it due to their masters's mistakes or madnesses: [[spoiler:Sairin and Keiki]] get better, [[spoiler: Hourin and Kourin]] do not.
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* ''Literature/{{Twilight}}'': This trope is the reason why Edward Cullen became a vampire. In 1918, a 16-year-old Edward and his mother were both dying from [[UsefulNotes/TheSpanishFlu Spanish flu]]... but [[MamaBear she]] used her last energies to take him to Dr. Carlisle Cullen, beg Carlisle to save her son ''at any cost'', then die.
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* ''Literature/{{Twilight}}'': ''Literature/TheTwilightSaga'': This trope is the reason why Edward Cullen became a vampire. In 1918, a 16-year-old Edward and his mother were both dying from [[UsefulNotes/TheSpanishFlu Spanish flu]]... but [[MamaBear she]] used her last energies to take him to Dr. Carlisle Cullen, beg Carlisle to save her son ''at any cost'', then die.
