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* HitAndRunTactics: Unlike others who depend on kiting with tears, Azazel often has to fly in, blast several enemies with brimstone, then get out of there before the rest retaliate.

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* HitAndRunTactics: Unlike others who depend on kiting with tears, Azazel often has to fly in, blast several enemies with brimstone, then get out of there before the rest retaliate. He can also strafe multiple enemies for the duration of his Brimstone but again he has to be closer than normal for tear-strafing.



* RequiredSecondaryPowers: A melee character would've been an interesting addition to the roster, but an actual melee attack would make multiple rooms UnwinnableByDesign. Azazel being equipped with the piercing brimstone and flight fixes both of these problems.

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* RequiredSecondaryPowers: A At the time, a melee character would've been an interesting addition to the roster, but an actual melee attack would make multiple rooms UnwinnableByDesign. Azazel being equipped with the piercing brimstone and flight fixes both of these problems. A true melee character eventually came along in the form of [[spoiler: The Forgotten]] with its own set of RequiredSecondaryPowers.


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* LuckBasedMission: The stats and item(s) you start off with are randomized each time, making it equally possible to have a strong early advantage or a really weak one. Most character power level discussions simply leave Eden out because of how much inconistent Eden runs are.


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* AwesomeButImpractical: Some of the Cambrion Conception minions are extremely good, like Brimstone Baby or Dark Bum (!!), especially when doubled with Box of Friends. You'll need to take at least 15 hits ''per minion'' though, which is easier said than done with Lilith's starting health.


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* MagikarpPower: If you can pick up more familiars or find a way to spawn at least one more with Cambrion Conception without dying, Box of Friends' effectiveness begins to multiply. Gaining boosts to spacebar charge rate increases how often she can double her army of minions, and BFFS just makes everything stronger.


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* MookMaker: Playable variant. Lilith starts with Cambrion Conception which permanently spawns a new demonic buddy after taking enough damage by giving birth to it, if the progressively more and more pregnant appearance is anything to go by.


* GoodCounterpart: He's basically Greed as a playable character.

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* GoodCounterpart: GoodCounterpart / TokenHeroicOrc: He's basically Greed as a playable character.Keeper monster who's on Isaac's side, and his combat style is identical to that of that of Greed.

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* FatBastard: It's all in their names.


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* FatBastard: Obviously, as he's the KingMook to the Fatty class of enemies.


* AllOfTheOtherReindeer: In addition to having an abusive mother and a DisappearedDad, flashbacks also show him suffering [[KidsAreCruel bullying from other kids]], such as having [[PantsPullingPrank his pants pulled down]] while trying to impress a girl, getting pooped on, getting knocked down by a dodgeball, and being made fun of for wearing a wig.

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* AllOfTheOtherReindeer: In addition to having an abusive mother and a DisappearedDad, flashbacks also show him suffering [[KidsAreCruel bullying from other kids]], such as having [[PantsPullingPrank his pants pulled down]] while trying to impress a girl, getting pooped crapped on, getting knocked down by a dodgeball, and being made fun of for wearing a wig.


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* BodyHorror: Homunculus's warped facial features.


* BanditMook: His shots (and [[CollisionDamage mere contact]] with him!) take away a couple of pennies from you, while making you drop a variable amount on the floor that you can try to retrieve. Just be careful while doing so, if you don't want to be [[DeathByMaterialism killed in the process]]. Oh! And guess what? His mook-look-alikes have the same ability as him. Yay!

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* BanditMook: His shots (and [[CollisionDamage mere contact]] with him!) him) take away a couple of pennies from you, while making you drop a variable amount on the floor that you can try to retrieve. Just be careful while doing so, if you don't want to be [[DeathByMaterialism killed in the process]]. Oh! And guess what? His mook-look-alikes have the same ability as him. Yay!him.



* KingMook: ''Wrath of the Lamb'' added Super Greed, who is bigger, meaner, scarier, and can spawn Greed-heads. Said Greed-heads also appear in the Depths, the Catacombs, and the Necropolis. [[spoiler:Also, the final boss of ''Afterbirth''[='=]s Greed Mode is Ultra Greed.]]

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* KingMook: ''Wrath of the Lamb'' added Super Greed, who is bigger, meaner, scarier, and can spawn Greed-heads. Said Greed-heads Keepers, who are essentially Greed heads. They can also appear in the Depths, the Catacombs, and the Necropolis. [[spoiler:Also, the final boss of ''Afterbirth''[='=]s Greed Mode is Ultra Greed.]]



* TheScrappy: {{Invoked|Trope}}. Given how he can replace shops and secret rooms, can knock out your money when he hits you, and can be fought '''multiple''' times in one run, players usually don't enjoy finding him. You'd be hard-pressed to find anything in the game that will make you madder than fighting Greed in the Depths/Dank Depths/Necropolis 2's shop or a Secret Room later and having him drop the Steam Sale when you have no use for it by that point in the game. He becomes an EnsembleDarkhorse [[spoiler:if you have the D20.]]



* MoneyForNothing: Invokes this; he gives a lot of money when defeated...but his battle has an infuriating tendency to replace the shop on the last floor where there would ''be'' a shop.
* UndeadChild: If the AlternateRealityGame is canon, he may be [[spoiler:Isaac's corpse.]]

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* MoneyForNothing: Invokes this; {{Invoked|Trope}}; he gives a lot of money when defeated...defeated, but his battle has an infuriating a tendency to replace the a shop on the last floor where there would ''be'' one. There's also a shop.
* UndeadChild: If the AlternateRealityGame is canon,
chance he may be [[spoiler:Isaac's corpse.]]might appear in Secret Rooms, making for a bit of a subversion.

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* EvilMatriarch: A monstrous final boss in the form of Isaac's mother.


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* VoiceOfTheLegion: Her dialogue consists of her screaming "Isaac" in a demonic voice.


* AllOfTheOtherReindeer: In addition to having an abusive mother and a DisappearedDad, he also suffered [[KidsAreCruel bullying from other kids]], such as having [[PantsPullingPrank his pants pulled down]] while trying to impress a girl, getting pooped on, getting knocked down by a dodgeball, and being made fun of for wearing a wig.

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* AllOfTheOtherReindeer: In addition to having an abusive mother and a DisappearedDad, he flashbacks also suffered show him suffering [[KidsAreCruel bullying from other kids]], such as having [[PantsPullingPrank his pants pulled down]] while trying to impress a girl, getting pooped on, getting knocked down by a dodgeball, and being made fun of for wearing a wig.

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* BloodyHorror: Lust seems to be affected with some sort of blood disease (likely HIV) and her Super variation bleeds from the face and leaves a trail of blood everywhere she goes.


[[quoteright:100:https://static.tvtropes.org/pmwiki/pub/images/pooter.png]]



[[quoteright:100:https://static.tvtropes.org/pmwiki/pub/images/pooter.png]]



-> Debut: ''The Binding of Isaac'' (Round Worm)\\
''Rebirth'' (Nightcrawler)\\
''Afterbith'' (Roundy, Ulcer)\\
''Afterbirth+'' (Tube Worm)



-> Debut: ''The Binding of Isaac'' (Para-Bite)\\
''Rebirth'' (Cod Worm)\\
''Afterbirth'' (Scarred Para-Bite)



* LosingYourHead: Scarred Para-Bites are Para-Bites with their heads ripped off.



-> Debut: ''Rebirth''



-> Debut: ''Rebirth''



-> Debut: ''Afterbirth''



''Wrath of the Lamb'' (Gut, Walking Boil, Walking Gut)\\
''Rebirth'' (Sack, Walking Sack)\\

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''Wrath of the Lamb'' (Gut, Sack, Walking Boil, Walking Gut)\\
''Rebirth'' (Sack, Walking (Walking Sack)\\



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* StationaryBoss: It always stays at the top center of the screen, no matter what.




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* StationaryBoss: Just like its living counterpart.



* FrickinLaserBeams: Much like the Vis enemies, their main attack is opening up their stomach and firing blood lasers. Except they use Mega Satan's giant version and can sweep the beam from left to right.

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* FrickinLaserBeams: Much like the Vis enemies, their main attack is opening up their stomach and firing blood lasers. Except they use Mega Satan's giant version and can lasers, although their's is much larger than normal. They usually do it facing towards each other, but if one is dead the other will [[OhCrap sweep the beam from it left to right.right]].




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* TurnsRed: When one Sister is killed, the other will literally turn red and begin moving faster.



* UndergroundMonkey: It's a much tougher version of Pin, but unlike the BackFromTheDead versions of other bosses, Scolex is noticeably different in appearance from its easier version.

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* UndergroundMonkey: It's a much tougher version of Pin, but unlike the BackFromTheDead versions of other bosses, Scolex is noticeably different in appearance from its easier version.
version (and was also in the game ''before'' Pin).



* DualBoss: He's the equivalent of fighting two Lokies at once, only with Red Boom Flies.

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* DualBoss: He's the equivalent of fighting two Lokies Lokis at once, only with Red Boom Flies.



* AsteroidsMonster: Except now filled with spiders instead of Chargers.
* BackFromTheDead: The Fistula has shrivelled up and now shelters spiders.
* BodyHorror: Like Fistula, it's named after a real-life BodyHorror phenomenon in which the body forms a growth containing all three germ layers, one of which can potentially manifest as ''bone shards and teeth!''

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* AsteroidsMonster: Except The same as Fistula, except now filled with spiders instead of Chargers.
* BackFromTheDead: The Kind of. It's the posthumous version of Fistula has shrivelled up and now shelters spiders.
in mechanics, although given that both are different real-life tumors without any personality or even attack method, it's hard to to say how "posthumous" they can really be.
* BodyHorror: Like Fistula, it's named after a real-life BodyHorror phenomenon in which the body forms a growth containing all three germ layers, one of which can potentially manifest as ''bone shards and teeth!''



* {{Expy}}: The fourth form of Gurdy to appear.

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* {{Expy}}: EmergingFromTheShadows: The boss screen shows her arm doing this. She actually looks like [[https://gamepedia.cursecdn.com/bindingofisaacre_gamepedia/0/0b/Mama_Gurdy_ingame.png?version=5286da1454db10196c163c99cd17983b this]] in-game.
* {{Metamorphosis}}:
The fourth form of Gurdy to appear.appear. This one is quite different than her predecessors - instead of a ball of guts with a human face, it's a (probably) humanoid creature that's misshapen and lumpy.




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* WeaksauceWeakness: She never creates spikes directly under the player, so standing still during her spike attack will leave you safe and her defenseless.
* ZombiePukeAttack: One of her moves has her spew orange vomit all over.


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* CompositeCharacter: She's Chub [[EquippableAlly wrapped up]] in a Fistula, although the boss doesn't actually take any attack patterns from those two.

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* DefeatMeansFriendship: It's [[MindScrew not clear whether or not they're the same entity]], but upon defeating Delirium for the first time, the player unlocks Lil' Delirum, who can help Isaac by shapeshifting in one of a handful of different familiars.


[[quoteright:161:https://static.tvtropes.org/pmwiki/pub/images/ultragreed.png]]

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[[quoteright:161:https://static.tvtropes.org/pmwiki/pub/images/ultragreed.org/pmwiki/pub/images/ultra_greed.png]]


[[ExactlyWhatItSaysOnTheTin Isaac's mother.]] A devoutly religious woman who, in a fit of rage/insanity/fanaticism/[[WildMassGuessing whatever you think it is]], she tries to kill Isaac, forcing him to flee to the basement.

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[[ExactlyWhatItSaysOnTheTin Isaac's mother.]] A devoutly religious woman who, in a fit of rage/insanity/fanaticism/[[WildMassGuessing whatever you think it is]], she tries to kill Isaac, forcing him to flee to the basement.



* {{Abusive Parent|s}}: Takes away all her son's stuff, locks him in his room, and then tries to ''kill him''. Convinced by God to do so or not, that's all the evidence you need. However, the true ending reveals that [[spoiler:this is possibly a subversion, depending on whether you see the between-level cutscenes as being canon or not.]]

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* {{Abusive Parent|s}}: Takes away all her son's stuff, locks him in his room, and then tries to ''kill him''. Convinced by God to do so or not, that's all the evidence you need. However, the true ending reveals that [[spoiler:this is possibly a subversion, depending on whether you see the between-level cutscenes as being canon or not.]]not]].



* {{Foreshadowing}}: The opening pretty much implies she's reenacting the role of Abraham, in Yahweh's covenant. [[spoiler:Which means, in case you're not a Bible buff, that this whole act is doomed to ''fail'' if she plays it as intended, as this time there's no angel to stop her and save her son's life.]]

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* {{Foreshadowing}}: The opening pretty much implies she's reenacting the role of Abraham, Abraham in Yahweh's covenant. [[spoiler:Which means, in case you're not a Bible buff, that this whole act is doomed to ''fail'' if she plays it as intended, as this time there's no angel to stop her and save her son's life.]]



--> “It was never implied that [Mom's] insane. And if you’re going by the Bible and you believe all the stories, [[BeliefMakesYouStupid then why wouldn’t you think that it’s possible now for that stuff to happen?]]”

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--> “It was never implied that [Mom's] insane. And if you’re you're going by the Bible and you believe all the stories, [[BeliefMakesYouStupid then why wouldn’t wouldn't you think that it’s it's possible now for that stuff to happen?]]”


* DifficultButAwesome: He plays ''nothing'' like any other character in the game, and you have to master being able to switch between the skeleton and its Soul when the situation best calls for it, which isn't easy considering that both the skeleton and the soul use different forms of health, and because of how they work, you can never have more than six bone hearts or six soul hearts. However, his melee attack is very powerful, and while the Soul is active, you can use the inactive skeleton to shield yourself from bullets without taking damage. The Soul also has flight and spectral tears, enabling him to fly over obstacles, pick up items, and fire through rocks just like the Lost, but without being a OneHitPointWonder. Additionally, because the bone hearts are not counted as red health, you can never lose a chance at a devil deal from taking damage. However, Devil Deals can only be taken by the Soul, so you have to have enough Soul/Black Hearts to survive it.

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* DifficultButAwesome: He plays ''nothing'' like any other character in the game, and you have to master being able to switch between the skeleton and its Soul when the situation best calls for it, which isn't easy considering that both the skeleton and the soul use different forms of health, and because of how they work, you can never have more than six bone hearts or six soul hearts. However, his melee attack is very powerful, and while the Soul is active, you can use the inactive skeleton to shield yourself from bullets without taking damage. The Soul also has flight and spectral tears, enabling him to fly over obstacles, pick up items, and fire through rocks just like the Lost, but without being a OneHitPointWonder. Additionally, because the bone hearts are not counted as red health, health unless you can never completely break a bone heart, so you won't lose a chance at a devil deal just from taking damage.damage as long as you can heal up. However, Devil Deals can only be taken by the Soul, so you have to have enough Soul/Black Hearts to survive it.



* LethalJokeItem: Size up items not only increase the Forgotten's size, they increase the size of his melee weapon, giving him greater reach. If you manage to stack enough of them, you don't even need to aim. Conversely, size down items should be avoided, as they will reduce his range for the same reason.

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* LethalJokeItem: Size up items not only increase the Forgotten's size, they increase the size of his melee weapon, giving him greater reach. If you manage to stack enough of them, you don't even need to aim. Conversely, size down items should be avoided, as they will reduce his range for the same reason. Thankfully, there is a hard minimum for the melee attack, so you can't render it completely useless.


* AmazingTechnicolorPopulation: Stat-boosting pills change the character's colour (Green for Luck, red for Health, etc), as do a few of the items. Most demon-related items turn the character into a black-skinned demonic hybrid, and Anti-Gravity turns them blue, for two examples.

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* AmazingTechnicolorPopulation: Stat-boosting pills change the character's colour color (Green for Luck, red for Health, etc), as do a few of the items. Most demon-related items turn the character into a black-skinned demonic hybrid, and Anti-Gravity turns them blue, for two examples.



* BlessedWithSuck: Guppy's Tail makes you find golden treasure chests more often. This comes at the expense of keys needed to open those chests, though if you're lucky, the chests cough them up. Works wonders with a Skeleton Key or a Flat Penny. This is made potentially worse or better with The Left-Hand item that changes all chests to Red Chests. They don't require a key to open, but half or more of the things that come out of a red chest are not something you want (including enemies and troll bombs).

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* BlessedWithSuck: Guppy's Tail makes you find golden treasure chests more often. This comes at the expense of keys needed to open those chests, though if you're lucky, the chests cough them up. [[CursedWithAwesome Works wonders with a items that can create keys, such as the Skeleton Key or a Flat Penny. Penny]]. This is made potentially worse or better with The Left-Hand item Left Hand trinket that changes all chests to Red Chests. They don't require a key to open, but half or more of the things that come out of a red chest are not something you want (including enemies and troll bombs).



* BodyHorror: Most of the powerups mutilate or mutate the character in some horrific way. For example, Chemical Peel causes half of the character's face to be torn off, Growth Hormones causes hideous lumps to form over the character's body, Steam Cells causes a fetus to grow on the side of the character's head, The Parasite burrows into the character's skull and dyes their tears a disgusting orange-brown, and 8 Inch Nails has two nails shoved [[EyeScream in each of of the character's eyes]].

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* BodyHorror: Most A ''lot'' of the powerups items mutilate or mutate the character in some horrific way. For example, Chemical Peel causes half of the character's face to be torn off, Growth Hormones causes hideous lumps to form over the character's body, Steam Stem Cells causes a fetus to grow on the side of the character's head, The Parasite burrows into the character's skull and dyes their tears a disgusting orange-brown, and 8 Inch Nails has two nails shoved [[EyeScream in each of of the character's eyes]].



** When using The Shears or Transcendence (the latter is permanent), Isaac floats around as a severed head. The former also turns his body into a secondary attacker, but only works for the current room.

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** When using The the Pinking Shears or Transcendence (the latter is permanent), Isaac floats around as a severed head. The former also turns his body into a secondary attacker, but only works for the current room.room.
** The Scissors does the opposite, and has your ''head'' become the familiar while you control the body. The severed head fires tears, though despite missing the head the body can fire tears as well... [[MindScrew somehow]].



** Leprosy causes chunks of flesh to fall off when you take damage, which then orbit around you and can damage enemies, as well as block projectiles.



* EyeScream: Some items cause this.

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* EyeScream: Some items cause this.Of multiple types -- The Peeper gouges one out of Isaac's head, while the Lead Pencil and 8-Inch Nails are jammed into one or ''both'' of his eyes, respectively.



** The Gambler: Keeper (only after unlocking Wooden Nickle).

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** The Gambler: Keeper (only after unlocking Wooden Nickle).Nickel).



* {{Flight}}: Plenty of items, both permanent and temporary. You can become an angel, a demon, an angelic ghost, a demonic ghost, a floating head, and a cat (which somehow flies). All of these let you pass through rocks and over pits.
** Becoming possessed by Guppy (the flying cat form) allows you to fly because why couldn't a possibly demonic cat possession also allow you to fly. Also, [[https://www.youtube.com/watch?v=Dt4zvJNXbdI it's a kitty cat]].

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* {{Flight}}: Plenty of items, both permanent and temporary. You can become an angel, a demon, an angelic ghost, a demonic ghost, a floating head, and a cat (which somehow flies). All of these let you pass through rocks and over pits.
** Becoming possessed by Guppy (the flying cat form) allows you to fly because why couldn't a possibly demonic cat possession also allow you to fly. Also, [[https://www.youtube.com/watch?v=Dt4zvJNXbdI it's a kitty cat]].
pits, as well as over hazards like creep and spikes.



* GoodWingsEvilWings: Both are possible -- Fate or Holy Grail for the "good" variant, Lord of the Pit for the "evil" one.
* {{Hammerspace}}: It's not specified where all the coins, keys, and bombs are stored.

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* GoodWingsEvilWings: Both are possible possible, though not at the same time -- Fate or Holy Grail Angel items for the "good" variant, Lord of the Pit and Devil items for the "evil" one.
ones.
* {{Hammerspace}}: It's not specified where all the coins, keys, and bombs are stored.stored, especially since Isaac is as [[NakedOnArrival naked as the day he was born]].



* ImprobableWeaponUser: Mainly his own tears. With appropriate items, he can upgrade to chocolate milk, urine, and explosive vomit, among other things.

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* ImprobableWeaponUser: Mainly his own tears. With appropriate items, he can upgrade to chocolate milk, teeth, urine, and explosive vomit, among other things.



* MeaningfulName: The names of all of the playable characters relate to Bible stories, with Isaac's name relating to the ''Binding of Isaac'' story the game is based on. ''Four Souls'' suggests his last name is Moriah, the mountain from the same story.

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* MeaningfulName: The names of all Most of the playable characters characters' names relate to Bible stories, with Isaac's name relating to the ''Binding of Isaac'' story the game is based on. ''Four Souls'' suggests his last name is Moriah, the mountain from the same story.



* SecretCharacter: There are numerous transformations available, which are activated by collecting three items of a particular set (flies, cats, etc.), after which the transformation effects are permanent for that run. The three items only need to have been held once, even if replaced (for Active items) or rerolled (for passive ones). The original had only Guppy, while ''Rebirth'' added Lord of the Flies. ''Afterbirth'' added eight more. ''Afterbirth+'' added a few more.

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* SecretCharacter: There are numerous transformations available, which are activated by collecting three items of a particular set (flies, cats, etc.), after which the transformation effects are permanent for that run. The three items only need to have been held once, even if replaced (for Active items) or rerolled (for passive ones). The original had only Guppy, while ''Rebirth'' added Lord of the Flies. ''Afterbirth'' added eight more. more, and ''Afterbirth+'' added a few more.another three.



** Also Lemon Mishap, which leaves a puddle that damages enemies.

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** Also The Lemon Mishap, Mishap item, which leaves a yellow puddle that damages enemies.enemies. The Lemon Party pill is an upgraded version, which creates a much larger puddle that does more damage.

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