These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
Luther Stickwell (a.k.a. "The Creeper") from the first game is a pimp, serial killer, paedophile, homophobe, murderous ghost... honestly, what can you say about a character that bonded three prostitutes to his stomach and turned them into Combat Tentacles? And there was that one line: "Remember, blood's the best lubricant!"
Copperfield the Slavehunter from Ties That Bind: besides his obsessive hunting of runaway slaves and their innocent ancestors, it's revealed that his hounds are starved before a hunt so that runaways will be horribly mauled or eaten alive when found.
Demonic Spiders: The Infernas were probably the all around fastest enemies in the game, could soak up a lot of damage, could hem you in by setting the ground on fire, possessed an area of effect attack, and always came in groups (and Jesus Christ, they were FAST!).
Fridge Brilliance: In 'Ties That Bind,' the Creeper was (in life) a serial killer and pimp who would murder women, mostly prostitutes. He displays massive misogynistic tendencies, as well as an intense mistrust for women, and will encourage Torque to do the same. And if you're playing on the Good side of things, Jordan betrays you, leaving the player with the possibility that the Creeper's twisted advice was actually useful.
If you read Ranse Truman's note during the load screen of "Lifetime Companion" and then finish your playthrough under Evil morality, you will realize what Ranse meant in his writing...