These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
Ozy and Millie have a debatable one. On the one hand, there's some Ship Teasing going on in a few select scenes. On the other hand, Ozy and Millie's parents married in the final story arc, making them siblings. On the other other hand, they're Not Blood Siblings. The prevailing opinion on the fan forum seems to be that either they'll end up together or at least one of them will end up transsexual; seeing as the creator of the strip is the latter herself, this seems plausible. This ends without a resolution; after the wedding, the last actual strip is them waking up in bunk beds and going outside to play; the last few pics of them asadults don't offer any hints either.
Tear Jerker: The story about Shelley, Ozy's biological mother. Sort of.
The Woobie: Ozy as above. Stephen as well...at least when it comes to romance (While nothing ever happened with Isolde, good or bad, the end of his crushes on Felicia and Stephanie both ended in pain: Felicia pretended to say she would go out with him, then mocked him with her Girl Posse and insulted him causing him to run away and Stephanie was only interested in being friends despite being perfect for him and was instead interested in Jeremy.). Millie is a minor example but has her moments.