These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
Complete Monster - Annie comes across this way in the movie, as we are not given much backstory or motivation for her horrific actions, and she just seems like an evil psycho. She's actually not a Complete Monster in the book though. For example, when she sees that Paul injured his hand by writing too much, she becomes genuinely upset. Paul thinks that "the occasional moments like this were the most ghastly of all, because in them he saw the woman she might have been if her upbringing had been right or the drugs squirted out by all the funny little glands inside her had been less wrong. Or both."
Hilarious in Hindsight: Paul's Misery series is focused on a pretty but flighty young woman who is the focus of two guys who do all the cool stuff. The series is obscenely popular. Fans, but especially middle-aged women, adore it. Critics everywhere skewer it. Almost twenty years later...
Two decades after Kathy Bates played Annie, she appeared in Midnight In Paris as Gertrude Stein, and the protagonist desperately wanting her to read his writing and hear her opinion is a plot point.
Hollywood Homely: Annie played by Kathy Bates is a plump woman of average appearance, clean and carefully groomed. The character in the book has been described as very unattractive, a shapeless fat body, reeking of dirt and poor-quality cosmetics.
Nausea Fuel: At one point Annie crushes a rat to death with her bare hand, poking her fingers into its body in the process. And then she licks her fingers. Paul wasn't the only one that felt ill.