This is not Owen Wilson's first time playing a cowboy - and in the sequel, we see his not-second-time getting buried up to his neck in sand. Bonus points for the inclusion of buddy-movie elements with Octavius.
Bonus BONUS points for Steve Coogan, who played Octavius, also having been in a buddy-type movie with Jackie Chan which also featured Wilson as one of the cowboy esque Wright Brothers.
Awesome Music: Both films end with disco-era tracks by Earth, Wind & Fire. The first one uses "September". The second uses "Let's Groove" (though it fades into something else as Larry meets the modern-day Amelia Earhart Expy).
The Other Darrin: Nick was played by Jake Cherry in the first two films, but then by Skylar Gisondo (who looks nothing like Cherry) in the third. It seems the movie is attempting a timeshifted actor, but both actors are of the same age.