Defictionalization: An official series of Murder, She Wrote novels claiming to be written by Jessica Fletcher "with Donald Bain" started in 1989 and continues to this day.
Hey, It's That Guy!: Recurring guest Harry McGraw is a lot more recognizable as Law & Order's Lennie Briscoe, and four-year series regular Sheriff Amos Tupper is equally more recognizable as Happy Days' Howard Cunningham. Other well-known guest stars who had later roles:
In "Murder at a Discount", George Segal's character is named Dave Navarro.
Technology Marches On: During the run of the show, Jessica goes from typing manuscripts on a typewriter to using a computer, as reflected in updated opening credits. The final movie shows that Jessica has even begun using a laptop.
What Could Have Been: Jean Stapleton, better known asEdith Bunker, was first offered the role of Jessica Fletcher. Stapleton passed - ironically, given that she's on record as being unhappy with her Type Casting as Edith, and this show likely would have rescued her from that fate. In any event, the producers then offered the role to their second choice, Angela Lansbury, who gratefully accepted.