- Wonder Woman (1987): Cassie is shown to have a Pantera poster above her bed in issue 178.
- Duke Nukem: The theme music, "Grabbag", is unabashedly influenced by Pantera, Ozzy Osbourne, Black Sabbath and Rick Wakeman.
- Heroes of the Storm: The guitars on E.T.C.'s back are in tribute to "Dimebag" Darrell Abbott and Randy Rhoads. His pink goatee is also inspired by the former as well.
- League of Legends: Olaf's Pentakill skin is based off of Vinnie Paul.
- Terraria: Plantera is an obvious nod to Pantera, creator Redigit's wife's favorite band.
- World of Warcraft: In Stormsong Valley, there is an unpainted tameable mechanocat named P4-N73R4.
- "Death Rattle" provided accompaniment to certain scenes in the Spongebob Squarepants episode "Pre-Hibernation Week".
