- In Wreck-It Ralph, the Hero's Duty game is a first-person shooter very similar to Call of Duty, and even the titles sound similar.
- In Dogs Don't Talk, Ben tells Philip that he doesn't play Grand Theft Auto because he prefers Call of Duty. Philip replies, "I don't play that game. I bet it stinks."
- The Angry Video Game Nerd: In his review of Day Dreamin' Davey, the Nerd compares the idea of Davey, a young boy, buying a gun, to playing a game of Call of Duty as a seven-year-old.
- Sonic Stopmotion Adventures: Someone orders Call Of Duty from Vector on a phone in Case Closed.
- Black Yoshi from SuperMarioLogan loves to play Call of Duty and many of his videos involve him begging Mario to buy him the newest Call of Duty games.
- An episode of The Loud House is entitled "Mall of Duty".
Other
- The "Press F to pay respects" meme was derived from a player prompt in Call of Duty: Advanced Warfare.