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- Spoofed in Rustlers' Rhapsody, where the cattle baron's daughter has been dragged behind her horse for hours. When Rex rescues her, she has only a tiny smudge on her cheek to show for it, which Rex tenderly wipes away.
- Inverted in The Mummy, where Imhotep's romance with Anakh-Su-Namun leads him to smear her body paint.
- A variation in Zombieland: Columbus discusses how his life's dream is to brush a girl's hair behind her ears.
- Subverted in Big, when Susan tries to get Josh to touch her by leaving a dab of mustard at the corner of her mouth, but being fabulously Genre Blind to romance tropes, he merely points out the mustard and never tries to clean it himself, even when she pretends not to know where it is.
- This happens early in the Left Behind series, when Chloe is eating a cookie and has a bit of chocolate on her cheek. Buck leans over and wipes it off with his thumb, then eats it on impulse. Cookies later become a romantic symbol for them.
- Happens in the second book of the Nightrunner series, although in this case Alec is dirtying a clean spot of Seregil's cheek for a disguise. Since this happens after Seregil has realized his feelings for Alec, but while he still believes they are completely unrequited, he is rather shocked.
Live Action TV
- Buffy the Vampire Slayer: A rare romantic moment passes between Willow and Xander in the season two episode "When She Was Bad", when Willow gets ice cream on her nose as the pair are walking past a cemetery. As Xander leans in to clean it for her, the two look like they are about to kiss... until a vampire pops up behind Willow, forcing Xander to attempt to hold it off and killing a Squee-inducing moment for Willow x Xander shippers.
- Willow later attempted to invoke this trope by putting ice cream on her own nose, but Xander, now once again distracted by Buffy, simply says "You got something on your nose."
- Parodied in the How I Met Your Mother episode "World's Greatest Couple", where Brad freaks out Marshall at dinner by licking his napkin and wiping a smudge of food off his face.
- A mild variation is invoked in Parks and Recreation between Leslie and Ben after the latter has dust thrown in his face as a fake Native American curse-lifting ritual.
- In the "Love And Monsters" episode of Doctor Who, Rose's mom used this trope on Elton to get him to take his shirt off.
- Averted in a famous sketch by German comedian Loriot. He tries to seduce a woman in an Italian restaurant, but happens to have a piece of noodle in his face. When she points it out, he removes it, but the next time he uses the napkin, the noodle returns to his face. Hilarity Ensues as the noodle moves around. No, he doesn't get the girl.
- A moment like this happens (oddly enough) in The X-Files episode "Red Museum". It was odd because it was supposed to be in the time period in which Chris Carter was adamantly denying any romantic feelings between Mulder and Scully. While investigating a case in cattle country, the two decide to eat at a local rib restaurant. In the middle of talking about the case they're on, Mulder just reaches over with a napkin and wipes a smudge of sauce off of Scully's face. Though taken aback, Scully graces him with a shy smile.
- Firefly example. In "Objects In Space", Mal tried to examine the blood stain on Inara's lip from where Jubal Early struck her. The spark when Mal's hand touches Inara's lip is all but visible.
- Scrubs: Towards the end of "His Story II," Elliot cleans the last little bit of clown makeup off of J.D.'s face (long story). Ten seconds later, cue makeout session.
- In the Glee episode "Wheels", Puck and Quinn have a playful food fight while making cupcakes for a bake sale. Puck goes to wipe flour off of Quinn's cheek and they lean towards each other... then Finn walks in.
- Korean drama Secret Garden has an oft-parodied variant, where the male lead gets rid of the milk on the female's lips by kissing her.
- In Northanger Abbey (ITV's 2007 TV movie), during Catherine's visit to the Abbey, Catherine and Henry go horse riding to see Henry's parsonage. When they reach it, it's about to start raining. Catherine suggests they race back to the Abbey. It's quite a rainy and muddy ride and at the Abbey, Henry cleans and caresses Catherine's face.
- The song "A Stud and a Babe" from the musical I Love You Youre Perfect Now Change features one of these in the middle. Subverted, because he doesn't actually do anything but tell her about it, and the romance fades fast after he does.
Guy: You, uh... you have some nacho schmutz on your face.Girl: (wipes) Gone!Guy: You, uh, you wiped it to the... other side. Now it's on your chin... better?
- In the song "It Won't Be Long Now" from In the Heights, the character Vanessa pauses to tell Usnavi he has "some schmutz" on his face and tries to wipe it off. He shyly tries to move away and the two stand there awkwardly until Sonnny appears and starts dancing with Vanessa.
- Subverted in El Goonish Shive, where Ellen goes to wipe a smudge off Nanase's face and she freaks out because she was having trouble admitting her attraction to Ellen, and moments like that only made it more awkward. Add to this the facts that Nanase used to like it when her last ex-boyfriend (Ellen's brother) did stuff like this and that the napkin was tucked in Nanase's blouse.
- In an episode of Young Justice, Me'gann accidentally spills all kinds of stuff on Superboy while trying to make dinner, which of course induces her to attempt to clean him up...and then right when they are about to kiss, Red Tornado walks in and they spring apart across the room. Superboy still with everything on him, staring at TV static. Yeah, not obvious at all.
- In Drawn Together, Xander does this to Toot when they're dancing together. Except, instead of a smudge, it's a whole piece of chicken removed from her face.