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Anime and Manga
- In Engaged to the Unidentified, Kobeni is said to have a weak constitution and get sick easily; and it seems that even something as simple as a shocking revelation can pretty much instantly bring on a severe fever. It's revealed that this happens because Hakuya gave her some of his magic power, and it causes stress to her body.
- As mentioned below Live Action TV, this trope hasn't fully disappeared in Asia. A few times in Fruits Basket, Tohru stresses herself out or gets upset and gets sick as a result. It usually plays out as the Sohmas putting her to bed and putting a cold compress over her forehead and her getting better after a good night's rest.
- In Higurashi: When They Cry, Hinamizawa Syndrome is a version of this combined with Hate Plague.
- Played completely straight in Brand Upon the Brain!. Mind you, Guy Maddin plays straight a lot of tropes that nobody else uses now—or ever.
- In Metropolis, Freder collapses with a fever when he thinks Maria has betrayed him.
- Played straight in Tai Chi Master. This happens to Jet Li's character after he is betrayed by his lifelong friend.
- In Therese, the title character becomes ill for two weeks after her oldest and favorite sister leaves to become a nun.
- In Soapdish, Elisabeth's Shue's character, Lori Craven, plays a destitute deaf-mute who is revealed to have Brain Fever during a live telecast of The Sun Also Sets.
- Joe Versus the Volcano. Joe suffers from a terminal "brain cloud". He's told that, anyway.
- This non-specific illness strikes Corrigan's child in 1915 silent film The Italian. And it doesn't appear to be something real like meningitis, because in the movie absolute silence is crucial to the girl's recovery, which would hardly be likely for a real illness, except for heat-induced migraines, since the baby contracted the fever during a heatwave, noting in passing that common febrile seizures were not well know at this time and could easily be confused with another heat-related malady.
- Invoked in Adventures of Huckleberry Finn: Huck is sneaking bread and butter out of the house by hiding it under his hat. When the (melting) butter starts to run down his face in front of Aunt Sally, she starts screaming that he has brain fever, and it's causing his brains to leak out.
- In A Little Princess, Sara's father dies of brain fever after going bankrupt. In just about every film version, he dies (or rather, "dies") in a war instead (The Second Boer War in the 1939 version and World War I in the 1995 version).
- In Agatha Christie's The Murder on the Links, a man collapses with a fever, which Hercule Poirot attributes to a shock on top of ongoing mental strain.
- Later Christie novels reflect the fact that Science Marches On. For instance, in The Big Four Hastings suggests that an insensible man is suffering from brain fever, to which a doctor character responds, "Invention of novelists!"
- Victor Frankenstein from Frankenstein had at least three bouts that lasted months, one of which was brought on by seeing his own monster. And the others from seeing its victims.
- The character Phillip Ammon suffers from Brain Fever after Elnora disappears from the swamp in A Girl Of The Limberlost.
- Appears in several Sherlock Holmes stories, including "The Copper Beeches," in which a girl's father pesters her about her inheritance until she gets brain-fever; and "The Adventure of the Naval Treaty," in which a man is ill for nine weeks after a treaty is stolen from under his nose. There's also "The Crooked Man", where the dead man's wife is rendered insensible for testimony by the same effect. note
- Dracula had Jonathan Harker suffer from brain fever when Mina finally found him after he somehow escaped the vampire's clutches.
- Wuthering Heights:
- Cathy (the first one) is very ill with brain fever, caused by a confrontation between herself, Edgar, and Heathcliff, during the first two months of her pregnancy. She never entirely regains her health, and dies two hours after the baby is born.
- Weirdly, she also suffers from this the first time Heathcliff disappears (though sitting out in the rain for hours could have had something to do with it—at least given the medical understanding of the day), but, when being nursed at Thornfield, manages to infect Mr. and Mrs. Linton with it. Somehow.
- When The Count of Monte Cristo opens, Captain Leclere has died of brain fever, leaving Edmond Dantès in command of his vessel.
"After a long talk with the harbor-master, Captain Leclere left Naples greatly disturbed in mind. In twenty-four hours he was attacked by a fever, and died three days afterwards."
- In Maurice, Maurice came "nearer to brain fever than he supposed" due to being worried about the state of his relationship with Clive while they were separated and... being too sentimental in their love letters. They meet up, decide to only write facts in said letters, and he recovers.
- In the Conan the Barbarian story "A Witch Shall Be Born", Valerius acts feverishly, babbling, thrashing, and giving Ivga a hard time quieting him. While he was wounded, it explicitly says that his mental torment was worse.
- In Crime and Punishment, Raskolnikov suffers a fever that becomes much worse after he goes through with his plan to commit murder, and Pulcheria Alexandrovna develops brain fever after her son is sent to Siberia.
- In La Dame Aux Camellias, Armand is already ill from grief after Marguerite's death, and develops a full-blown brain fever after seeing her body exhumed. In his case, the doctor declares it a fortunate occurrence: the physical illness will drive out the strong emotion, and prevent Armand from going mad with grief.
- In Foundations Triumph by David Brin, Brain fever is used by name and common among certain groups. It was genetically engineered by Daneel Olivaw to keep the Galactic Empire stable and people from asking certain awkward questions.
- In The Turn of the Screw, Flora becomes seriously ill and delirious after her governess accuses her of conspiring with ghosts.
- In Eragon, the first book in the Inheritance Cycle, the title character and his mentor, Brom enter the city of Teirm under the aliases of Evan and Neal. Brom plays the role of the slighty senile uncle and Eragon comments to a guard that he had a bit too much sun and now has a touch of the brain fever. After they are safely inside the city, Brom comments "A touch of brain fever?" and Eragon replies that he couldn't let him have all the fun.
- Although H.P. Lovecraft was more known to have characters Go Mad from the Revelation, this trope also cropped up occasionally in his work, such as the young artist's suffering in The Call of Cthulhu (although this, like many of Lovecraft's usages of Brain Fever, is ambiguous in that it might be the result of trauma, or possible a physical effect of the Great Old One's mental influence.)
Live Action TV
- Believe it or not, this is not a Forgotten Trope in Southeast Asia, where many a Korean Drama or Taiwanese Series has the hero/heroine collapsing due to stress, overwork, or convenience, and ends up being cared for by their significant other, often with comfort food and a cold compress across the eyes.
- Boys Before Flowers: This happens several times with Jeun Di, especially when she worked multiple jobs.
- Can You Hear My Heart: Dong Joo frequently would collapse with a fever as a consequence of his fall when he was eight years old. Luckily, Woo Ri was there to nurse him.
- Devil Beside You: Qi Yue gets to do the cold compress thing on Ahmon's brow.
- Japanese drama version of Hana Yori Dango: This happens twice between Tsukushi and Tsukasa, once in an elevator and once in a blizzard.
- Mars: It gave Qi Luo an excuse to take care of Chen Ling all night long.
- Personal Taste: Park Gae In gets fevers when she is on her period, leading Jeon Jin Ho to procure painkillers and rub her tummy all night long.
- Shining Inheritance: Go Eun Song helps an hurt old lady on the street; once her fever is down, it turns out the woman is the CEO of a giant food conglomerate.
- You Are Beautiful: Hwang Tae Young took care of Go Mi Nam when she developed a fever after getting wet.
- In "Qpid" on Star Trek: The Next Generation, the crew of the Enterprise and Picard's flame, Vash, are placed in a Robin Hood simulation. Vash is Maid Marian and is being ministered by a nurse, who says that she must have a brain sickness for sure. She offers to get some nice fresh leeches to drain the fever, which horrifies Vash.
- In Hannibal, Will Graham's slow slide into insanity is marked by feverish hallucinations, among other symptoms. He is revealed to be suffering a rare kind of encephalitis.
- Subverted in Tales of the Abyss, when Luke's mother falls ill after his sudden disappearance. Tear feels terrible, since she was the cause of Luke's vanishing, but Luke tells her that his mother has always been sickly - the stress of his disappearance might have made her worse, but it certainly wasn't the only cause of her illness.
- In a Pinky and the Brain short, the duo went to live with a group of Amish farmers for some reason, and at one point Brain explains Pinky's antics as the results of "the Brain Fever".
- In Avatar: The Last Airbender, Zuko spirals into an illness immediately after he frees Appa at the pinnacle last few episodes of the 2nd season, the explanation being that his inner turmoil had caused his body to react in a sickly fashion.
- Word of God states that the truly amazing longevity of Bumi, Guru Pathik and Avatar Kyoshi can be attributed to "balanced chi". If balanced chi can create health and long life, then perhaps unbalanced chi can create illness.
- It is a fact that depression and anxiety can cause one's immune system to weaken significantly, thus making one very susceptible to a wide range of health problems. When Iroh said that Zuko's illness was an emotional illness, he very well may have been correct. (If Zuko hadn't been so stressed-out and angry all the time, his infection most likely would not have manifested itself so severely.)
- On Daria, the title character is in the hospital for an embarrassing rash, and Jane, trying to make up an excuse for her whereabouts, tells Brittany that she has brain fever. ("It's a thing that brains get," but usually goes away after you read a bestseller.) Ironically the rash turns out to be stress-related, so it sort of fits this trope itself.
- Just like being cold, stress and mental shock can't literally make you sick, but they make getting sick much easier.
- Some drugs, including cocaine, can induce hyperthermia when overdosed. In the 19th century, administering cocaine to patients suffering from emotional stress might actually have induced the febrile state which this trope blames on mental causes alone. When Robert Louis Stevenson had a serious chest infection that was causing him to haemorrhage from his lungs, his doctors injected a vegetable alkaloid which probably saved his life, but caused him terrifying fever dreams that eventually inspired The Strange Case of Dr. Jekyll and Mr. Hyde. (At least, that was his story. He also used cocaine a lot too, mostly as a painkiller for his various aliments.)
- You'll find "brain fever" mentioned in most 19th century medical textbooks, so it wasn't "invented by novelists" as Christie's character says above. Conan Doyle used it frequently, and he was a doctor in Real Life. Any use before 1930 or so is more likely to be a case left behind by Science Marching On rather than outright ignorance on the part of the author.
- Shock could also be a reasonable explanation for some of the fictional reports, combined with PTSD and a stress-weakened immune system, along with, as mentioned above, meningitis and encephalitis.
- Delirium or hallucinations may be considered a sort of brain fever. Dehydration, lack of sleep, and overexertion can cause such effects.
- It could be a case of getting cause and effect the wrong way round—high temperatures caused by an infection not directly related to the brain can cause delirium or mental disturbance, especially in children.