Spider-Man 3 may be a fairly polarizing film but damn if everyone didn't well up a bit at the "Birth Of Sandman" scene. Watching Sandman at one moment barely able to stand up to forming a full body with steely determination after just one look at his daughter gets this troper everytime. The beautiful musical score and jaw-dropping visuals (When you can get a pile of sand to be on both the verge of tears and have a look of absolute determination, you're doing something right) only adds to it.
In Spider-Man 3, after Peter has shed himself of the alien symbiote and sits alone depressed in his apartment, Aunt May visits Peter to see how things have gone between her nephew and his fiance and asks if he's proposed to her yet. Peter tells his aunt that he's not ready for marriage because he had hurt Mary Jane badly and returns the proposal ring Aunt May gave him earlier in the movie, much to Aunt May's shock. In response, Aunt May replies by saying that Peter should forgive himself and that Aunt May believes Peter will do the right thing because she knows he's a good person and she knows he will find a way to make things right again and to give it time. This scene also serves as a Tear Jerker moment.
Aunt May: Well, you start by doing the hardest thing: You forgive yourself. I believe in you, Peter. You're a good person. And I know you'll find a way to put it right.
The ending of Spider-Man 3, where Peter and Mary Jane get back together again. Ever since his childhood, Peter wanted to be with Mary Jane, and being Spider-Man meant that it was all but impossible. Yet, Peter has finally managed to balance his personal life and his life as a superhero, conquered his dark side, made peace with his past by forgiving Sandman, and finally, after all he's gone through, he can spend his life with the woman he loves. The series began with him wanting to be with Mary Jane, and it ends with the two of them together.
The novelization features the original ending for the film. Harry and Peter are trying to defeat Sandman and Venom and even with the added help are having trouble. Then Sandman's daughter and ex-wife show up and beg Flint to stop, with his daughter telling him that he isn't a bad person. Flint returns to his human form but Venom begins to go on a rampage. Peter tells Flint to run and get his family out of there and the three leave.
In perhaps the best of Stan Lee's cameos (and Stan the Man's personal favourite), he muses on the impact of Spider-Man in fictional New York to Peter Parker. It's easy to interpret it as Stan talking about the greatest lesson comic book superheroes (particularly Spider-Man) try to teach their readers.
Stan Lee: You know, I guess one person really can make a difference. Nuff Said.