Burt holding the return policy of his nice shirt hostage on picture day.
Maw Maw getting fed up of being quarantined in "The Sniffles".
Burt: "There's a predator in your neighborhood. *cough* It's me."
That whole montage, and the scene at the end.
Burt getting freaked out by the computer. On it's own, it's funny. But it's hilarious when you remember that Dillahunt use to play a Terminator. Likewise when he gets snarky and snarks about going back in time to change events.
Burt trying to get Maw Maw to stop smoking. She immediately puts it out—on him.
All three of the possible ads for Howdy's Supermarket in "Baby Monitor"
The spitting contest between Burt and the alpaca in "Don't Vote for this Episode"
Also in that episode, when Kenny is convinced his store has a gypsy.
When Burt shows Hope the picture of her mom in the electric chair, Hope smiles and laughs.
Burt yells at a lobster he bought... Then immediately apologizes to it.
In "Henderson, Nevada Adjacent, Baby!" Sabrina says that Jimmy doesn't seem like the Vegas type.
Jimmy: That's because you only really know Daddy Jimmy. You don't know sex-in-the-back-of-my-van-with-a-serial-killer Jimmy. I used to be a wild man before this little ball and chain came and threw a wet blanket on my party fire. (Hope does something cute.) She is cute, though, isn't she? (devolves into Baby Talk)
Sabrina: You need to party.
Jimmy: Oh, I do.
Also in "Henderson, Nevada Adjacent, Baby!", the montage of Virginia trying to decide whether or not she should go to her terrible cousin's wedding, interspersed with Burt whittling an entire tree branch down to a toothpick.
The unfortunate soul who decided to video chat Maw-Maw. A naked Maw-Maw.
The fact that he later shows up for a date makes it even funnier.
Burt thinking Frank's killed Jimmy, and enters the house to catch Jimmy playing with dolls of himself and Sabrina.
Maw-Maw's series of ideas that would have been amazing 30 years ago. The best is how she comes up with the idea of a 24-hour cable news channel, then immediately dismisses the notion because she thinks it would lead to programs full of pundents just to fill time, which leads to partisan bickering, and thus is a terrible idea.
Opening scene in "Spanks Butt, No Spanks" Jimmy gives Hope her bowl of oatmeal, she throws the spoon at him and giggles. He tells her "Very funny, Hope, but you need your spoon to eat your oatmeal." Hope's response: No! *pushes bowl off table.*
Burt and the singing boob toy.
Pretty much the entirety of "Candy Wars".
From "The Last Christmas": Burt and the Alpaca, round two.
Maw-Maw vs. Sabrina. Maw-Maw pretty much kicks Sabrina's ass. While in a wheelchair with a broke pelvis after falling off the roof of a car she was car-surfing on.
Maw-Maw hears the rest of the cast up in the attic, and starts shooting.
Maw-Maw: "I hear you up their, mongooses!"
Virginia: "We're not mongooses!"
Maw-Maw: "That's just what a mongoose would say!"
A lot of "Jimmy & Sabrina's Wedding"
The banana-eating contest.
Maw-Maw: I haven't gotten a speeding ticket since 1962. Your about to find out why.
Maw Maw getting a lap dance from the pizza guy who they thought was a stripper.
Jimmy: Why are you getting a lap dance from the pizza guy who I went to high school with?