You can also reply by quoting Time Cube at him. Gives double positive influence, too.
The "Polite" response has Mike commenting, "That's quite possibly the longest single sentence I've ever read."
The NSA listening post in Rome. Mike's facial expressions in this scene are pure comedy gold. You'll know it when you see it.
One of Mike's possible responses when Deng orders him to get into a maintenance closet at gunpoint:
"This is going to end with me pointing out where you touched me on the doll, isn't it?"
If Mike is a veteran, while traveling through the catacombs of the ruins in Rome he'll start to hum something called "Sinister Music" by the subtitles. Mike actually sings the tune in time with the flickering lights.
If Mike agrees to let SIE...release him...and is agreeing to destroy Alpha Protocol, Westridge has some hilarious things to say about it afterwards.
Westridge: You did not just do that in my medical bay. Bet it smells like cat piss and tuna in there...
Mike getting fed up with Grigori and beating the crap out of him. It starts off as a bit shocking, but then turns darkly humorous from Mike's commentary.
Mike: (after smashing a bottle over Grigori's head) Aww, you spilled your wodka.
Sparing Brayko results one of the funniest news broadcasts in the game:
INN Newscaster: Authorities say that he will be charged as soon as he is well enough to be discharged. Mr. Brayko had no statement for the press, but while he was being loaded into the ambulance, he was heard to remark that the party responsible for the attack "an expletive American commando cowboy like the expletive offspring of Ronald Reagan and an expletive American Ninja." ... a source within the hospital stated, that, quote, "The man had enough cocaine in him to make a baleen whale see Jesus."
If you have Heck as your Handler during the endgame, you got this conversation when your chopper gets blown up.
Almost all of Heck's dialogue & actions for the final mission are hilarious, transforming what could otherwise be a tense finale into a ridiculously awesome action movie climax.
If you agree to let Albatross be your handler for the mission at the US Embassy in Moscow, and choose the Suave response:
Mike: Alright, I'll bring the marshmallows, you bring the hotdogs.
Albatross: This is no time to joke.
Mike: If you're too cheap to bring the hotdogs, just say so. Guess those G22 resources aren't all they're cracked up to be.
Aggressive!Mike is an endless font of misanthropic hilarity.
Mina: Now that you've made it to Taipei, what are your plans?
Mike: Mostly I figured I'd punch somebody until answers came out.
Madison: Ever hear of 'anger management'?
Mike: No, because I killed all my therapists.
Mina and SIE's sniping at each other. These two women really don't like each other.
Heck saves the day.He interrupts an otherwise tense moment with a magnificently-timed shotgun blast, and greets you like most would greet an old pal at a party, making a passing comment on how gross it is to bleed in a place like this, where the germs are probably as old as WWII. The secret WWII, not the usual one.
In the endgame, with the inimitable Steven Heck: 'Should I file that under M, for Mangled in Woodchipper, or W, for Woodchipper, Mangled?'
Brayko to Surkov: "Your bodyguard is busy winning gold medal in dying. I gave him 6.4 on the dismount but he did not stick the landing."
Heck: Oh, so you remember where they are now, do you?!
Wen:(screaming through his gag)
Heck: Candy dish?... Well, that does it, Wen, you know I don't like swee-
Wen:(more screaming, wild gesturing)
Heck:(looking to the side) Oh, the candy dish! That's right! That's where I left my keys! You should have said something earlier, Wen; you see what I almost made you drink?
During the final mission, if you've romanced SIE and Mina and subsequently rescue the latter.
Mina: Are those fingernail marks on the back of your neck?
Mike: I, uh... was attacked. I don't want to talk about it.
One of the email exchanges with Scarlet, where she jokingly mentions all the hot lesbian sex she has with the other photojournalists in her spare time:
Scarlet: I'd reward you with some hot lesbianic sex too but I don't think that would work, what with you not having a vagina and all.
Mike can taunt Marburg when they first meet in Rome, and ends up ripping into Leland along the way. The contempt and dismissal positively drip from his voice, in hilarious counterpoint to Marburg's low, raspy threats.
Mike: You answer to a cardboard cutout half your age with the fashion sense of a screaming child. He spends thousands on his fucking hair.