Safe Havens is a fantasy comic strip by Bill Holbrook, launched in 1988 and initially set in a daycare center. In 1993 the preschool children began aging in real time, and the strip has followed them as they've moved through K-12, college and now young adulthood. The main character is Samantha Argus, a personable and enthusiastic young woman with the skills of a Mad Scientist who has unlocked the secrets of genetic manipulation.
This comic contains examples of:
Absent-Minded Professor: Rupert and Rosalind are great geneticists but keep making trouble for themselves. Even more so when separate.
Acrophobic Bird: An unusual variation. The dodos drink a potion to grow eagle wings for a distant travel, but to no avail.
Artifact Title: For a while, anyway. Originally focusing on Safe Havens Daycare, it moved on to other schools with "Havens" in their names, and the main characters even started a band called Safe Havens. The band wasn't very central, and the "Safe" part still looked somewhat out of place. Nowadays, Samantha teaches at Havens University, and some of her friends' kids have enrolled in the daycare center.
The Bechdel Test: Passed on many occasions thanks to a strong female lineup and a female lead.
Breakout Character: Samantha used to be a supporting character, but she turned out more interesting than Matt.
Cats Are Snarkers: Palmtop. Then again, snark is pretty well distributed in this comic.
The Faceless: The extremely tall Don and Rosalind were portrayed as being so tall their heads were always off-frame. Averted with Rosalind when, thanks to some mad science, she shrank an entire foot and decided she liked being of normal height.
"Freaky Friday" Flip: Variant: Samantha and Dave, thanks to accidental lab potion ingestion, are turned into each other (Samantha's body turns into a duplicate of Dave's, and vice versa). On their Wedding Day, no less.
My New Gift Is Lame: Averted and then subverted. Despite the expectations of relatives, Samantha didn't mind inheriting only a ring from her grandma. Especially when she discovered that it acted as a sort of Video Phone to her grandma in Heaven.
Speaks Fluent Animal: Several characters can speak with animals, but only so long as they mentally retain some aspect of their childhood; those who "grow up" lose the ability and eventually forget they ever had it.