During a "Commercials That Never Made It To Air" round, Chris Addison makes a joke about Andy Parsons' baldness ("Do you suffer from dull, lifeless hair? Don't worry, Andy Parsons'll buy it off you.") Andy's response definitely warrants a mention:
Andy: How much did you say you earned for those Direct Line car insurance ads? Well, people deserve to hear about this! [mimes honking a horn, a la the advert]
Then one upped by Hugh Dennis:
Hugh: Dara O'Briain: We work, so he doesn't have to.
In fact, this one has been a Running Gag throughout several episodes.
Then one upped by Dara, who pretends to doze off.
"I'm so old, my pussy is haunted". - Frankie Boyle, mimicking the Queen
And a newscaster repeating it after it sparked outrage.
Hugh completing a stage of the Tour De France in real life. Not as impressive as completing the whole thing, but it still takes some balls to try.
Katherine Ryan recites a major part of the "Prince Ali" song from Aladdin from memory.
Hugh and Russel's argument about Harry Potter. Especially when Russel corrects his comment on Parselmouth.
"I think you'll find that's Parseltongue; ten points from Hufflepuff."