Episode 6. Kyohei Kadota singing and dancing when Kaztano regains consciousness. That's right. Steve Blum. Singing. And DANCING.
I have all the pawns I need...
The middle of episode 11 is this for Mikado. The episode then proceeds to 'maintain' the level of awesome, especially if you've watched Baccano!.
The true moment of awesome is when Mikado sends the email. Up to that point, everyone in the background of every episode is drawn in the same shade of grey. The moment that the email gets dispatched, everyone in that crowd starts being shown in full color.And people said the Dollars weren't a color gang...
Anri revealing herself as Saika's host by calmly stopping a knife with her forearm.
And eventually finding restraint to stop himself and being happy about it.
Walker strolling up to a van full of kidnappers and casually lighting them all on fire.
Holy crap yes! And he even opened his eyes!
Episode 22 Anri is about to be assaulted by some Yellow Scarves thugs, so the Dollars start banding together to try and help her escape. Everyone who is close to Anri's location start assisting her- giving her a chance to escape, making obstacles for the thugs, and even attempting to disguise her with a giant bunny costume. There truly is a power in numbers.
Masaomi single-handedly taking down a whole bunch of Horada's goons in episode 23, armed only with a Jimmy bar. Notably more awesome in the light novel, in which it takes a few cracked ribs and a lead pipe to the head just to get him down, but even then he's not out cold.
Mikado and Anri's respective entries in their Big Damn Heroes moment in episode 23. It's hard to decide which is more epic, Mikado skidding in on the back of Celty's motorcycle, or Anri slicing a steel door in half with Saika.