Kars and the Pillar Men

Towards the end of Battle Tendency, it's revealed how and why Kars created the Stone Masks. By creating these masks, Kars is indirectly responsible for the tragedies both the Joestars and Zeppelis face early on as well as serving in Dio's ascension and giving him his powers. This leads to the Joestars being intertwined in a fate in which each JoJo must do battle with evil.

Example of:
Greater-Scope Villain