- 12 Monkeys: Elrond Peredhil is sent back in time from an apocalyptic future to find the original plague virus, and suspects the Army of the Twelve Monkeys, an ecoterrorist group of which Aragorn is the psychopathic leader, to have done it. Nancy Thompson is a doctor who decides to help Elrond.
- 28 Days Later: Frank Castle, Xena, Owl and his daughter Natasha Romanoff are the survivors of a Technically Living Zombie apocalypse.
- 300: King Gaston and three hundred spartans (Gigolo Joe, Bill Johnson and his son James among these) fight off Zapp Brannigan's army at the Thermopylae until Dr. Doofenshmirtz betrays them.
- 1984: In a totalitarian dystopia, John Keating and Ruth DeWitt Bukater fall in love. Commander Rourke finds out and has them captured.
- 2001: A Space Odyssey: General Ripper investigates a mysterious black monolith found buried on the Moon. When another monolith shows up near Jupiter, a ship manned by astronauts Kuato, Prince Vultan and the supercomputer Mr. Ages is sent there.
- A Clockwork Orange: In his youth, Pacha was an ultraviolent delinquent with a hard-on for Beethoven.
- Adventures in Babysitting
- (1987): Kelly is the babysitter of Josee.
- (2016): Maya Hart and Amy accidentally swap cell phones, which ends up with Amy taking Maya's babysitting job.
- The Adventures of Huck Finn: Mira Nova and XR travel down the Mississippi River.
- A.I.: Artificial Intelligence: Following the global warming wipeout, Eliot Ness creates Tyler as the prototype of a faithful child robot, who gets adopted by Fegan Floop and Sally Jupiter. However he's abandoned after their real son Draco Malfoy returns and with the company of Malfoy's toy Lorenzini and Zaphod Beeblebrox he goes on a journey to find the Blue Fairy.
- Alice in Wonderland (2010): Bloom escapes from her wedding with the 11th Doctor chasing Shaggy and finds herself in Wonderland, meeting Sterling Archer, Gregory House and Sideshow Bob. She has to fight Vicky and her dragon Optimus Prime.
- Vicky's knave is The Grinch; Betty Brant is a white queen; Zeke is a bloodhound; Oracle is Bloom's Maiden Aunt; Leeron is his own twin.
- Alien: Ben gets infected by an alien parasite and dies giving birth to a monstrous creature that goes on to kill Yoda, Han Solo, Thusla Doom and Sharon Spencer while C-3PO turns out to be indeed a goddamn robot with a secret agenda and Madame Medusa is the final girl.
- Aliens: Madame Medusa returns to LV-426 with a group of space marines (Chucky, Alexander Knox, Sister Mary Clarence, Nada and James Cole among these) and adopts Violet Beauregarde, while Keyser Söze is a backstabbing bastard and Darth Vader is a good robot.
- Alvin and the Chipmunks: A struggling songwriter named Cosmo finds success when he meets three singing chipmunks: Stanley Yelnats, Yang, and Harry Potter.
- Squeakquel: Stanley, Yang, and Harry meet their female counterparts: Amber Von Tussle, Fiona, and Janet.
- Chip-Wrecked: Stanley, Yang, Harry, Amber, Fiona (now Zarina), and Janet get shipwrecked on an island, where they meet a castaway named Sophie Sheridan.
- Road Chip: The guys must stop Cosmo from proposing to Crimson, whose son is Trent. Luckily, it turns out that Cosmo was hanging on to the ring for his friend's proposal.
- The A-Team: Hannibal Chau, Yoon Tae-goo, Derek Zoolander and the Great Gazoo are elite operatives framed for a crime, and on a mission to clear their names.
- The Avengers: Basil of Baker Street, Bella Swan, and Earl gather these superheroes onto a team: Stu Pickles, Sesshoumaru, Eric Matthews, Simba, Syndrome, and Azula. They must stop Sam Winchester's alien army from destroying mankind.
- Avengers: Age of Ultron: Issachar is created and he helps them stop the robot uprise of Erich Ludendorff.
- Avengers: Infinity War: They fail to stop Jean-Luc Picard's snap, before undoing it and killing him once and for all in the sequel.
- Basic Instinct: Peter Venkman investigates a murder case and Galadriel uncrosses her legs during the interrogation.
- Batman (1989): Sarah and Alan Grant investigate the mysterious caped crusader Harry Hart, who goes up against the clown prince of crime, Carlito Brigante.
- Batman Returns: Hart (now Butch Coolidge) has to deal with the Mayor of Halloween Town and Melina, former secretary of the evil businessman Jimmie Dimmick.
- Batman Forever: After Patches O'Houlihan kills his parents, Jack gets adopted by Butch (now Daniel Dreiberg), who also has to deal with Mickey Knox and has a romantic relationship with Peg.
- Batman & Robin: Daniel (now Marco Pagot) and Jack are joined by Joy, and together they must stop Ra's al Ghul and Eris' evil scheme.
- Beauty and the Beast (2017): Angel Salvadore offers to become Star-Lord's captive in order to escape from Trunks.
- Beetlejuice: Sam Lowry and Honey Bunny die and befriend the goth girl Bridget Jones, but her father Santino Corleone and stepmother Winnie Sanderson are so obnoxious that they decide to summon Pennywise the Dancing Clown in the hopes of scaring them out of their house.
- BlacKkKlansman: With the help of K, Deadpool infiltrates into the Ku Klux Klan, lead by the Grand Wizard MacGruber.
- Blade Runner: Eddie Valiant hunts down a group of replicants lead by Montgomery Burns.
- Blade Runner 2049: Flip Zimmerman with his holographic Katniss tracks him down while being stalked by Bucky Barnes' henchwoman Juno.
- The Blues Brothers: Jack Goodman and Bugs Bunny must raise money to save their old orphanage.
- The Brady Bunch Movie: Benny and his wife Miss Clavel raise six children: Zack, Sharon Stone, Bromley, Daphne, Sheriff Callie, and Candace. Mollie is the family's housekeeper.
- Captain America: The First Avenger: Peter Parker is given a super serum by The Vulture after training under the guidance of Colonel Harry Lime and Cindy Campbell (who later becomes his love interest) and fights against the evil Lionel Cosgrove.
- Captain America: The Winter Soldier: Peter is surprised by the unexpected return of his old friend Niander Wallace.
- Captain America: Civil War: Peter fights Chief Wiggum, who wants Wallace dead for murdering his parents, and at the start of the battle Finn steals his shield.
- Carrie (1976): Jenny Curran and Sky Corrigan are the prom king and queen, at the suggestion of Sky's girlfriend Lin Bei Fong. However, Chris and her boyfriend Khan are plotting with blood.
- Carrie (2013): After being punished by Cow, Penny offers her boyfriend Cody Martin to ask Lilly Truscott to the prom. Ginny Weasley is the Alpha Bitch.
- Casper: Unikitty and her father Snake Plissken investigate a mansion where she befriends a ghostly Babe, who resides there with three other ghosts: Chum, Ted and Slater. Selene and Freddy Krueger are the villains.
- Cast Away: Agent Simmons is stuck on an island with a volleyball.
- Charlie and the Chocolate Factory: Daniel-san offers five children to tour his factory: Finn, Bambi, Darla, Little Suzy, and a German boy.
- Children of Men: Jack Sparrow helps a refugee pregnant girl escape from Britain, now a dystopian State since humanity has become infertile.
- The Chronicles of Narnia: The Lion, the Witch, and the Wardrobe: Nia, Jimmy Neutron, Charlie Bucket (later Jonesy), and Lilo discover a magical wardrobe that transports them into a magical kingdom.
- Cinderella: Madeline wants to go to the ball, but her stepmother Maleficent forbids her from doing so. With help from fairy godmother Kitty Galore, Christian Grey falls in love with Madeline.
- Conan the Barbarian (1982): Egon Spengler seeks revenge after his village is raided by the followers of Parker.
- The Dark Knight Trilogy: The saga of LEGO Batman as he fights crime with the aid of his butler Blain and commissioner Tony Stark. First against his former master Doug Quaid and Mike Shiner, then against Arthur Fleck and two-faced Seymour Krelborn, and finally against the masked brute Manny, who gets killed by Harley Quinn.
- Day of the Dead (1985): In the post-zombie apocalypse, Jessica Rabbit is stuck in a bunker with soldiers lead by Ash Williams while the head scientist Baron Münchausen tries to domesticate the undead.
- Dead Poets Society: Winston Smith is an English teacher who inspires his students Raleigh Becket, Tetsuo Shima, Obi-Wan Kenobi and Balto through his poetry lessons. Sam Eagle is the stern headmaster and J. Jonah Jameson is Raleigh's abusive dad.
- Deadpool: Oliver's girlfriend Rita Vrataski has been kidnapped! Fluttershy is the villain's partially mutated henchwoman with superstrength, Killmonger is Oliver's best friend, Shenzi is his blind roommate, Adolf Hitler is an Indian taxi driver and Steven Universe is the pizza delivery guy.
- Deadpool 2: Oliver wants to stop Diego from killing Miles Morales, who in turn wants to kill his abuser, The BFG. Ahsoka Tano is a mutant who can manipulate luck.
- Defendor: Daniel Jackson wants to be a superhero vigilante to avenge his mother. On his way he befriends the hooker Samantha Carter and deals with the corrupt cop Tallahassee.
- Demolition Man: Travis Bickle and his arch-enemy Bonkers are frozen and awakened in a crapsaccharine future in which Vilos Cohaagen wants to use Bonkers to kill the freedom fighter Maverick Mitchell, while Maid Marian becomes Travis' love interest.
- Dick Tracy: John Hammond adopts Tails as a sidekick and wants to take down the mob boss John Spartan and resist the temptations of his mistress, Demona. Hammond's true love is Julie Hastings.
- Die Hard: Winston Zeddemore takes over the Nakatomi Plaza and is up to Austin Powers to rescue his wife Audrey and stop the bad guys, with the support from Sergeant Immortan Joe.
- DodgeBall: A True Underdog Story: Prince Charming's gym is about to be bought by Timon. In order to raise enough money to cancel the purchase, Charming's Ragtag Bunch of Misfits (Dr. Hibbert, Jack Dawson, The Crimson Bolt and Skipper) enters a dodgeball tourney after training from Abis Mal. Charming is in love with Brenda Walsh, who likes unicorns. Adolf Hitler makes a helpful surprise cameo.
- Dragonheart: Initially Hades wants to kill The Genie thinking that his healing of Gerry Conlon corrupted him.
- Elizabeth: Anne Maria becomes queen of England.
- Edward Scissorhands: Prince Derek is an unfinished project who falls in love with Sierra.
- The Elephant Man: Henry Hill wants to help Tommy DeVito and give him a better life away from his abusive master Benny Hill.
- Escape from New York: Gandalf forces The Gmork to rescue Panoramix after his plane crashed in Manhattan, now a penal colony with criminals ruled by Richard Vickers. On his way, Gmork is aided by cab driver Foghorn Leghorn, Martin Kessler and his mistress, the Pigeon Lady.
- Event Horizon: Doc Brown built a spaceship that returned from Hell. Riddick will sacrifice himself to destroy it.
- Fatal Attraction: Shaft has a one night stand with Madison, who takes the "relationship" way too seriously.
- The Fifth Element: The original Beast Prince comes across Mulan and must save the world with the help of Judge Doom, Jack Sparrow and a hysteric Stewie Griffin while Homer Simpson is serving The Great Evil and wants to stop them at all costs.
- Final Destination 3: Juno has a premonition that a roller coaster will crash, killing everyone on board. After Harry Potter and Carrie fail to make it out alive; Juno, Myles Barton, Death the Kid, Ruthie Camden, Wimzie, Scaredy Squirrel, Ashlyn, Milly Thompson, and Bud Bundy are targeted by death itself.
- Flash Gordon (1980): Alec Travelyan and Saavik arrive in Mongo aboard Raymond Cocteau's rocket to stop the evil emperor Waternoose, who plans to destroy the Earth out of boredom. Sal is a forest planet prince and Sport is the leader of the Bird-Men.
- Frida: River Tam is an artist married to Lex Luthor.
- Get Him to the Greek: Mort has to bring rock stars Flim and Flam to their concert in Los Angeles.
- Ghostbusters (1984): Nick Curran, Frank Butterman and Conan organize a ghost-catching business, with Hans Gruber joining them as the final member.
- Good Will Hunting: Rick Sanchez is a math genius who can only find work as a janitor and is best friends with Ronan the Accuser. This changes when he meets a psychologist named Rex.
- The Good, the Bad and the Ugly: The Sheriff of Nottingham learns of gold buried in a remote cemetery, but he only gets half of the information, and the ghost of King Hamlet gets the other half, forcing the two to work together. Citizen Kane is a mercenary who goes after them.
- The Good, the Bad, the Weird: Plutarch Heavensbee steals what he thinks is a treasure map from a train carrying Japanese officers. He is forced to briefly team up with bounty hunter Wreck-It Ralph and is pursued by old adversary Phil.
- The Green Mile: Nicodemus (Ethan Hunt when he was adult) tells about his experiences as a death row guard when he met the condemned Joshua Sweet, who had magical healing powers, and also dealt with the sadistic guard Rock and the maniacal inmate Patrick Bateman.
- Guardians of the Galaxy: After the Beast gets abducted by Gonzo, he forms an unlikely alliance with Marinette, George Jetson, the original Beast, and Will Hunting in order to take down Chuckie. Marinette's sister is Kitty.
- Hairspray
- The Hangover: J.D. finds himself the Only Sane Man after a wild night in Vegas leaves him with a missing friend (Riley Poole) and new wife Brenda. J.D.'s other friends are Charlie Salinger and Herb Muddlefoot.
- Harry Potter and the Philosopher's Stone: Forrest Gump Jr. learns from Q that he's a wizard. Forrest leaves his aunt Snow White, uncle Jumba, and cousin Billy Elliot behind to attend Hogwarts, a school for young wizards. At Hogwarts, Forrest befriends Kohaku and Alice and forms a rivalry with Light Yagami. The instructors at Hogwarts include Headmaster Mufasa, potions master Boingo, and charms instructor Vizzini. He gets his first wand from Mr. Miyagi.
- Harry Potter and the Chamber of Secrets: Forrest meets Kohaku's parents (Anne Lewis and Peter Griffin), Light's dad Lord Shen and Zorro joins the teachers. In the end he defeats Steve Rogers saving Kohaku's little sister Shuri and frees Sam Wilson.
- Harry Potter and the Prisoner of Azkaban: Forrest and friends meet his dad's friends Hades, Hank Hill, and Guido. Demona joins the teachers.
- Harry Potter and the Goblet of Fire: At the Triwizrd Cup, Forrest does battle with Loki, while Mufasa suspects a conspiracy set by Yamato, on orders of Hamlet to kill Yamato's father Palpatine. Mrs. Copperbottom is a reporter.
- Harry Potter and the Order of the Phoenix: Belle breaks out of jail to join Hamlet while Lydia Adams brings chaos to Hogwarts.
- Harry Potter and the Half-Blood Prince: Mrs. Doubtfire comes out of retirement to stop a war while Forrest and Mufasa visit Hamlet's past.
- Harry Potter and the Deathly Hallows: Kohaku, Alice, and Forrest find that Father has taken over the Ministry of Magic. Turns out Maka Albarn's dad is just as crazy as her. Forrest seeks help from Cleo, and Clayton is Mufasa's brother.
- Hellboy (2004): Baby Herman adopts Dr. Zoidberg, who works along with the amphibian Chirrut Îmwe and is in love with the pyrokinetic Buttercup, and together they must stop the apocalyptic scheme of the powerful sorcerer Pumpkin, who's assisted by Sheila Broflovski.
- Hellboy II: The Golden Army: Chirrut and Rei Ayanami fall in love, but they'll have to deal with her evil brother Peter LaFleur. The heroes are joined by Dr. Bunsen Honeydew.
- High School Musical: Matilda tries to sabotage Carmen and Juni Cortez's relationship.
- The Hobbit: King Candy goes on a quest with Rocky Balboa and his fellowship: Wolverine, Goemon Ishikawa XIII, Jack Burton, Nathan Bunce, Donnie Darko, Pinocchio, Bigweld, Calcifer, Captain Metalbeard, Jethro, Teal'c, Serk Brantner and President Lindberg.
- In the sequel Maximus Decimus Meridius is a dragon!
- Home Alone: 1971!Charlie Bucket sets up various traps to fend off against the burglars Chester Phillips and Eustace Bagge before his mother Maddie Fenton comes back home. Buck Turgidson is an old sinister neighbor who saves Charlie.
- Home Alone 2: Lost in New York: Charlie stays at the Plaza Hotel where he antagonizes with the concierge Buzz Lightyear and befriends Queen Elizabeth the pigeon lady.
- Hook: Simon Phoenix returns to Neverland to save his children Max and Sarah from his old nemesis Captain Tony Montana, whose first mate is Han Solo.
- Hot Fuzz: Milo Thatch is reassigned to a rural village and paired with Dewey Finn, son of the Inspector Ray Stantz. When gruesome murders start happening, the shady supermarket manager Johnny Bravo becomes Milo's prime suspect.
- Hot Tub Time Machine: Daggett, Mort, Maurice, and Rico travel to the past. Jing-Mei Chen is a Manic Pixie Dream Girl; Django may be the Time Police, and Kick Buttowski saves Dave's arm.
- The Hunger Games: Tinkerbell, Phineas, and Curtis fight for their lives. Along the way, Tink replaces her sister Anais at the death match, is trained by Giles, interviewed by Wanda, given fashion help from Louis, does battle with Arrietty, Ilana, and Harry Potter, all while being watched over by president Darth Vader and Taran.
- Catching Fire: Tink and Phineas return to the death arena to face-off against past victors, including Jack Frost (from District 4) and Zoey (from District 7).
- Ichi the Killer: The Man with the Yellow Hat is a sadomasochistic yakuza enforcer who is enchanted by the carnages left by Pennywise, a murderous man-child hypnotically controlled by Mr. Pink.
- Idiocracy: Legolas is accidentally left in hypersleep for 500 years along with Janine Melnitz and wakes up in a dystopia of dumb people where he befriends Barry Bee Benson and becomes the next President after Hellboy.
- In Bruges: Kim Jong Il sends Bootstrap Bill Turner and 2005!Willy Wonka in Bruges so that Turner can kill Wonka for accidentally shooting a child, and things get complicated.
- Inception: Kevin is a thief who enters into people's dreams to extract valuable secrets, and Hard Master offers him to erase his criminal history if he convinces Mark Watney, son of Hard Master's competitor Mr. Tweedy, to dissolve his father's company.
- Inglorious Basterds: Padmé wants to blow up a theater to kill Orson Krennic and gets the attentions of the war hero/actor Anakin Skywalker. Meanwhile Big Daddy leads a team of soldiers (Kenshiro, Rolf and Quackerjack among these) to kill Nazis and the actress Mary Jane Watson joins them after a shootout in a pub in which Luke Skywalker was undercover as a Nazi.
- Iron Man: Superman becomes a literal man of steel.
- Or Leroy Jethro Gibbs is a millionare playboy philantropist superhero.
- Jawbreaker: A mean-spirited prank played by Jane Porter, Amy Wong and Taylor ends in a girl's death. Maria Kelly learns about the truth and aligns with Taylor and her boyfriend Derek to take Jane down at prom.
- Jaws: Chief John Merrick (Cordell Walker in the redub) and the oceanographer Charles Deetz (Herbert West in the redub) set sail with Gimli (Don Lino in the redub) to hunt down a dangerous great white shark.
- Jem and the Holograms: Living with their aunt Atta, four girls (Disgust, Princess Aurora, Tina Cohen-Chang and Mary) become pop stars, after Disgust's video earns a million views in one moment. Big Bad Julie and her son Prince Charming hears about it and wants to sign Disgust and company for her record label. After getting fired, Julie forms a rival band with Carrie, 2013!Kiki, Hannah Montana and Tip to overthrow Disgust. Sailor Jupiter makes a Remake Cameo as the hairstylist. Professor Barkin and May Kanker are also there.
- Jingle All the Way: Clubber Lang is panicking to get an action figure for his son Devon Murray in time for Christmas, but postman Anton Chigurh is after the same toy and makes matters worse.
- Johnny English: Odo is a James Bond parody.
- Jumanji (Don Bluth-styled): Stanley takes Rosie/Gus and their sister Anne-Marie into a board game.
- Jurassic Park: Dick Tracy has built a park of cloned dinosaurs and invites the paleontologists Gomez Addams and Sarah Connor, his nephews Simba and Gwenie and the chaos theorist Jareth over to see it. Everything falls apart when Dark Helmet sabotages the park to steal some embryos for Barry Sembène's company. Roger Rabbit is a cowardly lawyer and Captain Rhodes gets killed by a clever girl.
- The Karate Kid: King Harold is the mentor of Spike.
- The Next Karate Kid: Harold's new apprentice is Rachel.
- The Karate Kid (2010): Aang is taught by Lucius Malfoy.
- Kick-Ass: Rick Ricker tries to be a Real Life superhero but comes across the vigilantes Aldo Raine with his daughter Debbie and Scott Pilgrim, who's the son of the Big Bad mob boss Jim Gordon.
- Kung Fu Hustle: Minion wants to become a criminal by joining Kakihara's gang, and is accepted after he breaks Donald the monkey out of prison to fight the landlady Arianna Dell'Arti and her husband Master Yo.
- Kung Fury: Springer is a badass cop who travels back in time to kill Soos before he kills him. Springer gets aid from Clyde McBride to go back in time, but he goes too far back and ends in the Viking era, where Button's mom, Anko and Martian Manhunter help him to get to Nazi Germany. When he almost dies, all his friends and his new partner Zenyatta help him to fight Soos and his army.
- Labyrinth: The Goblin King Edgar Friendly kidnaps Terk's baby half-brother and gives her 13 hours to get through his labyrinth and save him. On her way, she befriends Mr. Spock, the Terminator and Teddy Roosevelt.
- Lady and the Tramp (2019): Lars and Belle's dog Marinette finds love with a stray dog named Reef. When Belle and Lars have their baby, Lars' aunt Kaorinite watches the baby.
- The Last Airbender: Noah is prince of the Fire Kingdom, Gumball was a Human Popsicle who is now the Last of His Kind, Lyra and Cilan are siblings from the Water Tribe, and Punch is Noah's uncle.
- The Last Circus: After Roger Smith loses his father Vinny Santorini by the hands of Alfred Pennyworth, he goes on to join a circus where he falls in love with the trapeze artist Claire Dearing, but unfortunately this causes trouble with her abusive boyfriend Rocket Raccoon.
- The Lighthouse: James T. Kirk is stuck on an island with Cyrus "The Virus".
- Mad Max: Fury Road: Rick Flag escapes whilst helping Ma-Ma take some fertile women to safety away from the merciless warlord Immortan Al Powell.
- Madeline: Zinnia Wormwood runs a boarding school with 12 girls (including Satsuki, Ed, and Hannah Montana).
- The Magnificent Seven (1960): don Vito Corleone, Little John, Dutch, Moses, Cornelius, Max Bercovicz and Roger Radcliffe are hired to protect a small village in Mexico from a group of marauding bandits lead by Merlin.
- The Magnificent Seven (2016): Just as the Foreman is on a killing spree, Ella recruits Fred Flintstone, Lance Starling, Taran, Judah, Major Monogram, Lance and Red Harvest to put an end to it. This was done with help from the latest Gumball.
- The Martian: Alexander the Great has to survive alone on Mars before his crew lead by Erica Albright comes back while on Earth Miller argues with NASA Chief Director Rick Ford on what to do.
- Mary Poppins: Felicity Fox is a magical nanny who takes care of Paul Kersey's children, Marty McFly and Pollon. Frederick Frankenstein tags along.
- Mary Poppins Returns: Felicity (now Cherry Darling) comes back to take care of Marty's (now Monkey D. Rufy) children. Dick Grayson is Frederick's successor.
- Matilda: Candace discovers the gift of telekinesis. She deals with her parents Ruth Embry and Itchy, older brother Merry, and school principal Jill Munroe. Dakota is Candace's teacher.
- Mean Girls: Homeschooled student Willow Rosenberg meets the "Plastics" clique: Alpha Bitch Josee, Dumb Blonde Mami Tomoe, and Melody. Then Willow falls for Josee's ex-boyfriend Sam Winchester.
- In the sequel, Sailor Jupiter joins a rich-girl clique with Alpha Bitch Sanders, Amethyst, and Hannah Montana.
- Meet the Parents: Liz Lemon introduces Todd to her parents Clayton and Fa Li. Meanwhile, Liz's sister ShinVision!Sailor Jupiter is marrying Jimmy.
- Meet the Fockers: We meet Todd's parents King Llort and Harriet Walsh.
- Mike and Dave Need Wedding Dates: Brody and Scott invite Cindy and Bobby Brady to their cousin's wedding.
- Mission to Mars: Bofur, King Julien, Dr. Drakken and Gale Weathers go to Mars to rescue Greg Universe.
- Moon: Bruce Banner works alone on the Moon with the sole company of the A.I. Truman Burbank.
- Mr. Nobody: Centenary Darkwing Duck (Peter B. Parker when he's adult) tries to remember his life and imagines various timelines in which he's married to Jean, in others to a mentally unstable Lapis Lazuli, and in others he's in love with Paprika.
- The Neverending Story: Kevin McCallister happens upon a magical book that tells of Peter Pan, who is given the task of stopping the Nothing from engulfing the world of Fantasia. Trimaxion is a flying dragon, Sy Parrish is a wolf monster and in the end Kevin names the Empress Tanya Mousekewitz.
- The Nice Guys: John Wick pairs up with Richie Tozier and his daughter Nui Harime to investigate the death of a porn star and the disappearance of Carol Davis, Shimi Skywalker's daughter. Ron Stoppable is a deadly hitman.
- No Country for Old Men: Alucard escapes custody and goes on a rampage to retrieve the money Eddy took for himself. Robert Freeman wants to find and protect Eddy while Dr. Franken Stein is tasked to kill Alucard and get the money. Katara is Eddy's wife.
- Office Space: Courage is a frustrated and unmotivated programmer who becomes enlightened after Boss Nass' hypnosis session. Billy and Tito are his best friends, John Winchester is his neighbor, Heidi becomes his love interest and Oogie Boogie is his loathed boss, while The Ice King really wants his stapler back.
- Oldboy (2003): After Black Dynamite is kidnapped and kept imprisoned for 15 years, he seeks revenge on whoever did it. It turns out to be Sideshow Bob, who is vengeful himself because back in high school Black Dynamite revealing the incest he had with his sister drove her to suicide. The revenge is complete when he tricks Black Dynamite into having sex with his own daughter, Dot.
- Oz the Great and Powerful: Thor arrives in Oz where he befriends a flying J.D., a porcelain Elsa Korr and deals with the three witches Cappy, Padmé Amidala and Joyce Byers.
- Pacific Rim: Five years after losing his brother Shang, Atreiu is recruited by Samurai Jack and paired up with his adoptive daughter Cassandra Anderson to co-pilot a mecha against Kaijus. Atreiu's rival is Holland March, son of Spider-Man Noir, Turk and Brainy Smurf are a scientist duo and John Kimble is an underground trafficker.
- The Parent Trap: California girl Fionna meets her British twin Louise Belcher at a summer camp. Posing as each other, the girls try to stop Tarzan from marrying Sugar. In the end, Tarzan and Annie Porter reunite.
- Peter Pan: The boy who never grew, Harry Potter, takes Gerti Giggles and her brothers Shishinki and Nemo to Neverland where they fight the pirate crew of Captain Green Goblin and his first mate Oswald Cobblepot.
- Pirates of the Caribbean: The Curse of the Black Pearl: Nicholas Angel teams up with Sterling Archer to rescue Jenny Foxworth from Patrick Star.
- Pirates of the Caribbean: Dead Man's Chest: Archer wants to get Popeye's heart to avoid being killed by his Kraken, but Master Crane wants to get his job back by delivering the heart to Fred Fenster while Nicholas wants to destroy the heart in order to free his father, Koichi Zenigata.
- Predator: The Shredder, Richard Thorndyke, Farmer Maggot, Buggin Out, Don Diego de la Vega, Mr. Bean and the Balloon Lady are stalked in the jungle by an alien hunter.
- The Princess Bride: Fredo Corleone reads to his sick nephew Pinocchio a story about the love between Leonidas and Veronica Quaife, who gets kidnapped by a trio of bandits (Private Joker, Nute Gunray and Marsellus Wallace) and with whom the evil prince John Malkovich wants to get married. Marsellus kills René Belloq to avenge his father.
- The Princess Diaries: Sara Lavrof (later Rapunzel) discovers that she is the heir to her grandmother's throne.
- The Professional: Morpheus takes care of Kim Possible and has to face off against the psychotic DEA agent Mike Wazowski.
- Pulp Fiction: Two hitmen, Neo and Dodger, go get a briefcase for Indigo Montoya, Dodger dances with Montoya's wife Lonette and Angelo Pappas cleans things up after Mullet is accidentally shot. Meanwhile Danko is a boxer who wants to retrieve the golden watch of his father Red Redding (which his girlfriend Emily forgot to pack) before leaving town but ends up at Scott Calvin and Childs' rape dungeon with Montoya. Otto Octavius and Lois Griffin try to commit a robbery at a diner where Neo and Dodger are eating.
- Return to Oz: Lydia Deetz returns in the Land of Oz and finds it in ruins. With the help of her new friends Finnis Everglot, 2017!Scrooge McDuck and Rattigan, she escapes from Magica De Spell and goes to Dr. Rumack's Mountain to confront him, rescue Louis Winthorpe III and restore Carmen Ibañez's rule over Oz.
- The Revenant: After being attacked by a bear, Dwayne is left for dead by Rust Cohle and his hunting party.
- RoboCop (1987): A turtle named Speed is rebuilt into a cyborg by William Riker, and with the help of Molly Weasley he hunts down the gang of the ruthless criminal David Bowman, who left him for dead. In the end Carr Gomm allows him to kill Martin Crane by firing him. Kent Brockman and Udonna are news anchors.
- RoboCop (2014): Greedy CEO Wreck-It Ralph profits from Superman being blown up in order to make him into a human robot and open the American market to drones, but Tony Stark, after initially going along with it, realizes how horribly Ralph is behaving, and tries to help Superman protect himself from the evil hunter Ross Geller. During all of this Superman's wife, Serena Van Der Woodsen, is determined to get her husband back, and Steele is a pretty biased TV newscaster.
- The Running Man: Darth Vader, under the false promise of his friends Nick Fury and Rorschach being spared, participates in the deadly TV game hosted by Lex Luthor. Evelyn Nesbit becomes Vader's love interest.
- Scooby-Doo: Rouge, Cosmo, Knuckles, and Cyclops are teenage detectives; Donkey's the Team Pet. They come to Don Karnage's island to investigate a haunting. Ed goes demon on them.
- Scooby-Doo 2: Monsters Unleashed: While Cosmo falls in love with museum curator Kylo Ren, Dr. Kelso is the Red Herring of the new case, but the real bad guy turns out to be Sarousch, who disguised himself as Angela and was helped out by her cameraman.
- Scott Pilgrim vs. The World: Simon has Randall for a roommate, is in a band with Bella Swan and Jacob Black, and his sister is Connie. One day, Simon meets the girl of his dreams (Gwen Grayson), who challenges him to fight her evil exes Sam, Noah, Iron Man, Turbo Thunder, Peggy Olsen, and two Asian brothers.
- Shaun of the Dead: Zim and his deadbeat best friend Keroro must survive the zombie apocalypse.
- The Shawshank Redemption: Hans Landa and Uncle Phil bond over a number of years in prison, finding solace through acts of common decency. Max Schreck is the warden and William Stryker is the brutal captain of the prison guards.
- Showgirls: Wendy Darling moves to Las Vegas to become a stripper.
- The Silence of the Lambs: Odette teams up with Bender to solve a murder mystery and save Babs from Crank.
- The Sisterhood of the Traveling Pants: Mikey, Luanne Platter, Starfire, and Melody find a magical pair of jeans that perfectly fits each of them.
- In the sequel, we see what Melody (now Mikey), Mikey (now Kagome), Luanne, and Starfire (now Go Go Tomago) are doing over the summer.
- Slumdog Millionaire: The flashbacks on Hiccup and Polly Purebred's lives, before Hiccup was accused of cheating in a game show.
- The Sorcerer's Apprentice: Based on the Fantasia sequence. Smithers selects Draco Malfoy as his apprentice so they can fight Caesar Flickerman and possibly Persephone.
- Spaceballs: Dennis Nedry wants to kidnap Elvira as she escapes from her wedding with her droid Dorothy (who has her voice) and comes across Agent J and his buddy Goose Bradshaw who decide to help her out, while Nedry goes after them with Col. Nathan Jessup and President Vladimir Harkonnen.
- Spider-Man: Numbuh 1 is bitten by a genetically altered spider while visiting a science lab with his best friend Flik and his crush Colette Tatou, and after the death of his uncle Mr. Potato he decides to be a superhero who fights against crime and the evil of Red Guy and works as a freelance photographer for Roy Batty.
- In Spider-Man 2 he faces off against Lucius Malfoy.
- In Spider-Man 3 he fights against Stan Smith and Johnny Rico and makes his love interest jealous after kissing with Vanessa Bloom.
- Spy Kids: Hermione Granger and Draco Malfoy must save their spy parents Miles Raymond and Uhura with a little help of Draco's idol Remus Lupin.
- Spy Kids 2: They butt heads with Ron Weasley and Luna Lovegood while exploring the island where Bing Bong created weird animals.
- Soul Surfer: Sailor Venus is a surfer who survives a shark attack.
- Star Wars: A New Hope: Superman leaves home after coming across the droids R2-D2 and Ash to rescue a princess. Captain Dallas is a smuggler and Bagheera sacrifices himself to allow them to escape from President Snow, who turns out to be the Man of Steel's dad in the next film.
- The Empire Strikes Back: Superman gets trained by Brett while in Cloud City Nearly Headless Nick betrays Dallas and gets him frozen in carbonite.
- Return of the Jedi: Nick (now Crocodile Dundee) helps the heroes rescue Dallas and Superman goes to face off against his father and Walter Paisley.
- The Phantom Menace: John Trent discovers the Force sensitive child Harry Potter, but when Kaecilius strikes him dead, his apprentice Bagheera (now Leonard "Bones" McCoy) promises to train Harry. Ash (now Arthur Weasley) meets R2 for the first time and in the end Paisley (now Betelgeuse) becomes the new Chancellor.
- Attack of the Clones: Harry grows up into Inuyasha, forms a forbidden love with Shosanna Dreyfus and avenges his mother Coral, while Bones chases Lloyd Christmas on Geonosis and is captured by Papa Beaver. An army of Lloyd clones comes to the rescue and Eeyore cuts Lloyd's head off.
- Revenge of the Sith: Just as Inuyasha kills Papa Beaver (now Adam Sutler) and Bones kills Nick Sax, Betelgeuse (now Snape) shows his true colors and Inuyasha helps him kill Eeyore joining the Dark Side and they turn the Republic into an Empire.
- The Force Awakens: Crimson and Brody Nelson team up with Dallas (now Smee) and Chewbacca to track down Superman. Skeleton King is the new Big Bad and Cedric Diggory is Smee's son.
- The Last Jedi: Crimson is subconsciously puzzled by Superman now having Magneto's voice. Meanwhile, due to the uncooperative general Ludmilla, Tommy Wiseau sends Brody and Jailbreak on a mission to get a codebreaker, but the two get Nero instead, who ends up backstabbing them.
- The Rise of Skywalker: Snape reveals to be still alive and to be Crimson's grandfather, Magic Mike betrays the First Order and Crocodile Dundee (now Yao) shows up with an army for the good guys.
- Starship Troopers: Philip J. Fry, his love interest Nabiki Tendo and his psychic best friend Anakin Skywalker join the military to fight space bugs. At boot camp, Fry gets trained by RoboCop, becomes friends with Sam-I-Am and Julia is attracted to him, but he still has in mind Nabiki, who meanwhile works with his love rival Judge Dredd. Fry takes over after his teacher-turned-lieutenant Yondu Udonta dies in combat.
- Super: Rhomann Dey and Luv become two deranged vigilantes after Dey's wife Arwen is taken away by Tyler Durden.
- Superbad: Jake Peralta and Chiro want to lose their virginity with Ming Fleetfoot and Wednesday Addams before graduation, but things get out of hand. Morty Smith gets involved due to his fake driving license and Hermes Conrad and Arthur Dent are two stupid cops.
- Superman Returns: The Flash must stop John McClane from building a continent of kryptonite.
- Super Mario Bros..: Indiana Jones and Ghost Rider are two plumbers who have to stop Hannibal Lecter from merging his dimension with theirs so they can rescue Princess Erin Brockovich.
- Superstar: Kate Holbrook is a wannabe star, who lives with her grandmother. At school, she competes with Esmeralda for the feelings of Luke Skywalker.
- Tango & Cash: Captain Hook and Les Grossman team up to take down the crime lord James Bond.
- Tammy: Kikyo is having a really bad day.
- Taxi Driver: Raymond Babbitt is a disillusioned cab driver who becomes a vigilante after developing a deranged hero complex and wants to rescue Molly Jensen from Alan-a-Dale.
- Thelma & Louise: Sophie and Gadget are on the run from the police after killing Hexxus, an attempted rapist.
- They Live: Slinky finds a box of sunglasses that allow him to discover a subliminal alien invasion. Raymond Holt helps him after a beatdown, Uncle Ben is a drifter who sells himself to the aliens and Rem is a news channel assistant who backstabs Holt because she also sided with the aliens.
- The Thing (1982): Richter, Maynard, R.K. Maroon, Johnny Utah, Steve Freeling, Frank Drebin, Clarence Boddicker, Royal Tenenbaum, Mr. Helpmann, Comic Book Guy, Sherman Klump and Clark are stuck in an Arctic outpost with a malvolent and deceptive alien organism.
- This Is 40: The Bad Teacher and Adult Simba struggle with their lives at 40.
- Total Recall (1990): Thanos saves Mars from General Zod and his henchman R.J. MacReady after killing his fake wife Ellie Sattler and gets with the freedom fighter Catwoman. Mr. Fox is a cabbie, Dr. Treves is the resistance leader who hides in the belly of his conjoined twin Dick Jones and Dr. Logan tries to give Thanos a red pill.
- Trading Places: Mr. Creosote and Bob Kelso make a bet that involves switching the roles of Adam Maitland with Ace Ventura. Nick is Adam's butler and Holli Would is a hooker who helps him out.
- Tropic Thunder: Ip Man, The Comedian, Otis, Caleb Smith and Ruby Rhod get in trouble in the Vietnamese jungles while working on a war film based on the fake accounts of Murray Franklin. Meanwhile Ian Malcolm is a foul-mouthed producer and Donnie Brasco wants to make sure Ip Man gets his contractual TiVo.
- The Untouchables: With the guidance of The Child Catcher (who later gets killed by Drax the Destroyer), Jack O'Neill recruits Movie!Jack O'Neill and Barf into a team to take down the crime boss John Rambo.
- The Usual Suspects: Edward Nygma tells Hudson of the twisty events leading up to a horrific gun battle on a boat, which began when he and four other criminals (Wolverine, Bud Fox, Tugg Speedman and Private Pyle) were told by Will Munny that a feared and mysterious criminal mastermind wants them for a job or else he'll kill them for revenge. In the end Nygma turns out to be said mastermind and gets away with it.
- Transformers: Human teenagers Mark Zuckerburg and Amanda Bynes watch the Autobots led by Goliath fight the Decepticons led by Fire Lord Ozai.
- Twilight: Kagome is caught in a love triangle between werewolf Nibbler and vampire Charles Xavier.
- The White The Yellow The Black: Bre'r Rabbit has to deliver ransom money for a missing pony.
- Who Framed Roger Rabbit: Detective Rick Deckard must prove that Data didn't murder HAL 9000. The real killer was Khan Noonien Singh. Data is married to Sugar Mama.
- Willy Wonka & the Chocolate Factory:
- (1971) Dr. Strangelove distributes five golden tickets across the world in hopes of touring his chocolate factory to five lucky children.
- (1983) Bart Simpson gets a golden ticket that allows him to visit Daisuke Jigen's candy factory and passes his Secret Test of Character, while Captain Underpants, Newt, Leeloo, and Samvise Gamgee fail.
- The Witches (1990): Alice plans to kill every child on Earth by turning them into mice.
- The Wizard: Phineas runs away from home and goes to California, winning a videogame tournament in the process. His father Pete, his brother Kid Muscle and agent Excalibur are searching for him.
- The Wizard of Oz: A twister takes Amy Fowler Kane in Oz where she tags along with the Cheshire Cat, Pat Hendry and Colonel Hathi to meet Henry F. Potter. Betty Boop is the wicked witch while Katie Nanna is the good witch.
- (1982) Yzma finds herself in Oz, befriends Marsellus Wallace, Happosai and LeFou to meet Barney Rubble while being targeted by the wicked witch, Mrs Hudson.
- (1985) Lara Croft finds herself in Oz, befriends Dr. Neo Cortex, Colonel Pierre and Vladimir Lem to meet Pingu. Sara Goldfarb is the wicked witch and Hazuki's mother is the good witch.
- The World's End: Harry Osborn drags his old high school friends Jeff Portnoy, Ziggy, Dale Doback and Cam Tucker into a pub tour.
- A Wrinkle in Time (2018): After her father Gary Goodspeed goes missing, it is up to Riley Anderson, her brother Chip, her classmate Bill Denbrough, and three travelers (Louise Sawyer, Joyce Byers, and Mulan) to save him.
- X-Men: First Class: Stifler starts a school for mutants and tries to put Ned Flanders on a better path, but he's too consumed by the desire of avenging his mother and all the suffering Jules Winnfield subjected him to by killing him.
- Year One: War Machine and Frodo Baggins Walk the Earth after being banished from their tribe.
- Young Frankenstein: Bert follows his grandfather's footsteps and creates Bishop with the help of Snoops and Wendy Torrance. Barsa is Bert's wife, Captain Quinn is the village inspector and saying Mrs. Baylock's name out loud scares horses.
- Zack and Miri Make a Porno: Faye Valentine and Jesse Cardoza become pornographers.
- Alternately, Jacques and Taylor make a porno.
- Zathura: Koda finds a magical SciFi-themed boardgame that takes his older siblings Charlie Bucket and Dorothy Gale to an adventure. The Narrator is an astronaut Dorothy is attracted to until she learns it's a grown up Charlie.
- Zombieland: Kick-Ass and Mickey Mouse are survivors of the zombie apocalypse and they meet Mitsuki and her little sister Mermista. Surprise cameo role courtesy of Roger.
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