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* What Zero did to Big Boss: After supposedly being best friends and brothers in arms, Big Boss turned on Zero and left the Patriots. Zero's revenge? Have Snake "kill" Big Boss (in ''VideoGame/MetalGear2''), retrieve his body, and keep it barely alive on life support, using him as the ''only'' working key to his super computer network that he chose to be his successor. [[FromBadToWorse And if that wasn't bad enough]], it turns out that Big Boss is not simply in a coma - he's actually in a permanent state of [[AndIMustScream locked-in syndrome]], a state maintained by the nanomachines injected into his body by the Patriots. As a result, he cannot move, speak, or do anything, but he is fully aware of his environment. Okay, he can thrash about a little bit - which only makes it worse. And of course, it turns out they did this to Solidus too.

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* What Zero did to Big Boss: After supposedly being best friends and brothers in arms, Big Boss turned on Zero and left the Patriots. Zero's revenge? Have Snake "kill" Big Boss (in ''VideoGame/MetalGear2''), ''VideoGame/MetalGear2SolidSnake''), retrieve his body, and keep it barely alive on life support, using him as the ''only'' working key to his super computer network that he chose to be his successor. [[FromBadToWorse And if that wasn't bad enough]], it turns out that Big Boss is not simply in a coma - he's actually in a permanent state of [[AndIMustScream locked-in syndrome]], a state maintained by the nanomachines injected into his body by the Patriots. As a result, he cannot move, speak, or do anything, but he is fully aware of his environment. Okay, he can thrash about a little bit - which only makes it worse. And of course, it turns out they did this to Solidus too.

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