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* An alien version in ''The Literature/GiantsSeries'' by Creator/JamesPHogan. The Ganymeans genetically-modified themselves to remove their secondary circulatory system, which was primarily a defense mechanism. Then it turned out that they needed it after all.

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* Literature/{{molesworth}} parodies the idea (which showed up often enough in 1950s SF) in ''Whizz for Atomms'', with typically idiosyncratic molesworth spelling:
-->''Well everyone use their branes so much that in the end they are all going to turn into eggs becos they will have thort a way of getting along without walking. This will not be until 21066 a.d. (approx.) but it makes you think a bit.''


* In Creator/MikhailAkhmanov and Christopher Gilmore's ''Literature/CaptainFrenchOrTheQuestForParadise'', the titular protagonist has 2000 years ([[TimeDilation subjective time]]) or 20,000 years (objective time) over his new wife, who is only in her 50s (but looks 20 thanks to the omnipresent cure for aging). The first thing he does after taking her onboard his ship is to have her examined by the ship's AutoDoc. The doc revealed something horrible to French - she still has an appendix. Angry at the carelessness of her home planet's religious fanatics, he has the AutoDoc remove the "offending organ" despite the fact that there was ''nothing wrong with it''.

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* In Creator/MikhailAkhmanov and Christopher Gilmore's ''Literature/CaptainFrenchOrTheQuestForParadise'', the titular protagonist has 2000 years ([[TimeDilation subjective time]]) or 20,000 years (objective time) over his new wife, who is only in her 50s (but looks 20 thanks to the omnipresent cure for aging). The first thing he does after taking her onboard his ship is to have her examined by the ship's AutoDoc. The doc revealed something horrible to French - she still has an appendix. Angry at the carelessness of her home planet's religious fanatics, he has the AutoDoc remove the "offending organ" despite the fact that there was ''nothing wrong with it''. The justification is that it's too risky to have one in space, since it may burst while you're away from the med-bay (e.g. EVA).


* In the 2012 ''Comicbook/AlphaFlight'' miniseries, those who have been through the Master of the World's evolution/brainwashing machine can be identified because they only have four toes. They also don't have an appendix, but that's a little harder to verify in the street.



* In the 2012 ''Comicbook/AlphaFlight'' miniseries, those who have been through the Master of the World's evolution/brainwashing machine can be identified because they only have four toes. They also don't have an appendix, but that's a little harder to verify in the street.



* The genetic manipulation side is handled fairly well in Literature/{{Schismatrix}}. The Shapers are engineered to not only go without appendices, but also to not need any of the bacteria humans currently need to digest food properly, allowing Shaper habitats to be free of any non-engineered nasties. Unfortunately for them, not everybody has this advantage; Shapers going from the aseptic environment to a bacterial one tend to get diarrhea, nausea and horrible rashes. Non-Shapers living in their habitats have to agree to get their intestines pumped and eat regular doses of foul-tasting yoghurt full of digestive enzymes to make up for it.
* This is exhibited by the children in Nicole Luiken's ''Violet Eyes.''
* H.G. Wells designed the Martians in ''War of the Worlds'' by turning this trope UpToEleven: he started from a humanoid body plan, then stripped off ''everything'' -- limbs, digestive tracts, sexual reproduction -- that he thought mechanization and/or medical technology could potentially make obsolete. All that he left them was a giant head, a few tendrils for pushing buttons, and the ability to breathe. Instead of eating, they drain captured aliens and humans of blood and inject it into their bodies.
* The futuristic anatomical doll in the short story "Mimsy Were The Borogroves" lacked an appendix, and a distinguishable large intestine for that matter. It also had at least one entirely new organ system, suggesting changes were engineered rather than evolved.
* Creator/PhilipJoseFarmer's ''The Wind Whales of Ishmael'' features a race of four toed future people.
* The Hive Series by Creator/TJBass features a race of Nebish -- four feet tall, four toes, pink blood due to lack of hemoglobin...
* In the Literature/DoctorWhoNewAdventures spin-off novels, the companions Chris Cwej and Roz Forrester have no appendices. They're from the 30th Century.



* In the ''Literature/DoctorWhoNewAdventures'' spin-off novels, the companions Chris Cwej and Roz Forrester have no appendices. They're from the 30th Century.
* The ''Hive Series'' by Creator/TJBass features a race of Nebish four feet tall, four toes, pink blood due to lack of hemoglobin...



* The futuristic anatomical doll in the short story "Mimsy Were the Borogroves" lacked an appendix, and a distinguishable large intestine for that matter. It also had at least one entirely new organ system, suggesting changes were engineered rather than evolved.
* The genetic manipulation side is handled fairly well in ''Literature/{{Schismatrix}}''. The Shapers are engineered to not only go without appendices, but also to not need any of the bacteria humans currently need to digest food properly, allowing Shaper habitats to be free of any non-engineered nasties. Unfortunately for them, not everybody has this advantage; Shapers going from the aseptic environment to a bacterial one tend to get diarrhea, nausea and horrible rashes. Non-Shapers living in their habitats have to agree to get their intestines pumped and eat regular doses of foul-tasting yoghurt full of digestive enzymes to make up for it.
* This is exhibited by the children in Nicole Luiken's ''Violet Eyes''.
* H.G. Wells designed the Martians in ''Literature/TheWarOfTheWorlds'' by turning this trope UpToEleven: he started from a humanoid body plan, then stripped off ''everything'' limbs, digestive tracts, sexual reproduction that he thought mechanization and/or medical technology could potentially make obsolete. All that he left them was a giant head, a few tendrils for pushing buttons, and the ability to breathe. Instead of eating, they drain captured aliens and humans of blood and inject it into their bodies.
* Creator/PhilipJoseFarmer's ''The Wind Whales of Ishmael'' features a race of four-toed future people.



* This trope was facetiously employed in ''Series/PhilOfTheFuture'' when Phil ran into a problem: he would have to be seen barefoot to stamp tomatoes in a farm on a class trip, but in his time, no one has pinky toes. To quote Phil's mother [[SciFiWritersHaveNoSenseOfScale "They won't lose their pinky toes for another 70 years."]] Ironically, pinky toes are actually used for balance.



* ''Series/DoctorWho'': Lady Cassandra, from five billion years in the future, who appears in [[Recap/DoctorWhoS27E2TheEndOfTheWorld "The End of the World"]] and [[Recap/DoctorWhoS28E1NewEarth "New Earth"]], is the self-proclaimed "Last Human" and is nothing but eyes and a mouth on skin stretched trampoline-like in a frame, attached to her BrainInAJar. However, in her case it's because she's had extensive plastic surgeries, ''not'' evolution, as the latter episode shows humans and human-descendants who look perfectly normal.
* This trope was facetiously employed in ''Series/PhilOfTheFuture'' when Phil ran into a problem: he would have to be seen barefoot to stamp tomatoes in a farm on a class trip, but in his time, no one has pinky toes. To quote Phil's mother [[SciFiWritersHaveNoSenseOfScale "They won't lose their pinky toes for another 70 years."]] Ironically, pinky toes are actually used for balance.



** In the episode "Lady Bouvier's Lover," Homer is worried that Abe marrying Marge's mother would make him and Marge brother and sister, and as a result turn the kids into "...horrible freaks with pink skin, no overbites, and five fingers on each hand!" Right after Homer says this, the camera points at the kids, who instead of being drawn in the Simpsons style, are drawn "horrifically" normal.

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** In the episode "Lady Bouvier's Lover," Lover", Homer is worried that Abe marrying Marge's mother would make him and Marge brother and sister, and as a result turn the kids into "...horrible freaks with pink skin, no overbites, and five fingers on each hand!" Right after Homer says this, the camera points at the kids, who instead of being drawn in the Simpsons style, are drawn "horrifically" normal.


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* This is mentioned as one of the results of human evolution in ''Series/TimeTrax''.

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* This Losing the appendix is mentioned as one of the results of human evolution in ''Series/TimeTrax''.

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* This is mentioned as one of the results of human evolution in ''Series/TimeTrax''.


* In ''TabletopGame/{{GURPS}}: TranshumanSpace'' No Appendix is an advantage that the Alpha genetic upgrade and Zisudra parahuman have, both templates are intended to be an "ideal" human.

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* In ''TabletopGame/{{GURPS}}: TranshumanSpace'' TabletopGame/TranshumanSpace'' No Appendix is an advantage that the Alpha genetic upgrade and Zisudra parahuman have, both templates are intended to be an "ideal" human.


** This is actually a plot point in Asimov's ''Literature/TheEndOfEternity'', when two of the main characters, both time travelers, who were born three million years apart notice that the only difference between them is the lack of wisdom teeth and the lack of appendix in the one from the later time. They (perhaps hastily) draw the conclusion that [[KnightsTemplar Eternity]] was trying to prevent human evolution.

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** This is actually a plot point in Asimov's ''Literature/TheEndOfEternity'', when two of the main characters, both time travelers, who were born three million years apart notice that the only difference between them is the lack of wisdom teeth and the lack of appendix in the one from the later time. They (perhaps hastily) draw the conclusion that [[KnightsTemplar [[KnightTemplar Eternity]] was trying to prevent human evolution.


-->-- '''Barbara''', ''PhilOfTheFuture''

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-->-- '''Barbara''', ''PhilOfTheFuture''
''Series/PhilOfTheFuture''






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* The Hive Series by {{T J Bass}} features a race of Nebish - four feet tall, four toes, pink blood due to lack of hemoglobin...

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* The Hive Series by {{T J Bass}} Creator/TJBass features a race of Nebish - -- four feet tall, four toes, pink blood due to lack of hemoglobin...






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* Parodied in ''DrKatzProfessionalTherapist'': when Ben is due to have his wisdom teeth removed, Laura mentions she never had them, which her dentist attributed to her being "more evolved". They end up getting into an argument over the veracity of the statement.
* Also parodied in ''WesternAnimation/TheSimpsons'', where a news report says that scientists predict people will evolve an additional finger in the future. Characters on the show have only three fingers and a thumb on each hand.

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* Parodied in ''DrKatzProfessionalTherapist'': ''WesternAnimation/DrKatzProfessionalTherapist'': when Ben is due to have his wisdom teeth removed, Laura mentions she never had them, which her dentist attributed to her being "more evolved". They end up getting into an argument over the veracity of the statement.
* Also parodied in ''WesternAnimation/TheSimpsons'', where ''WesternAnimation/TheSimpsons'':
** Parodied when
a news report says that scientists predict people will evolve an additional finger in the future. Characters on the show have only three fingers and a thumb on each hand.






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* ''Manga/MyHeroAcademia'' uses toe joints as indicators. People with three joints are considered part of the old generation and are [[{{Muggles}} quirkless]]. Meanwhile, people with two joints are the next stage of human evolution, and are born with Quirks.

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* ''Manga/MyHeroAcademia'' uses toe joints as indicators. People with three joints are considered part of the old generation and are [[{{Muggles}} quirkless]]. Meanwhile, people with two joints are the next stage of human evolution, and are born with Quirks.
[[StockSuperpower Quirks]].

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[[folder: Anime and Manga]]
* ''Manga/MyHeroAcademia'' uses toe joints as indicators. People with three joints are considered part of the old generation and are [[{{Muggles}} quirkless]]. Meanwhile, people with two joints are the next stage of human evolution, and are born with Quirks.


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* The Comicbook/{{Legion Of Super-Heroes}} would have us believe that in 1,000 years humans will grow an ''extra heart''. Forgot the fact that an extra pump in our chest would cause more problems than it would solve.

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* The Comicbook/{{Legion Of Super-Heroes}} ComicBook/LegionOfSuperHeroes would have us believe that in 1,000 years humans will grow an ''extra heart''. Forgot the fact that an extra pump in our chest would cause more problems than it would solve.



* In ''{{GURPS}}: TranshumanSpace'' No Appendix is an advantage that the Alpha genetic upgrade and Zisudra parahuman have, both templates are intended to be an "ideal" human.

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* In ''{{GURPS}}: ''TabletopGame/{{GURPS}}: TranshumanSpace'' No Appendix is an advantage that the Alpha genetic upgrade and Zisudra parahuman have, both templates are intended to be an "ideal" human.



* Some people don't grow wisdom teeth. [[InvertedTrope On the opposite end,]] some people have them but don't need to get them pulled.

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* Some people don't grow wisdom teeth. [[InvertedTrope On the opposite end,]] end]], some people have them but don't need to get them pulled.


-->--'''Barbara''', ''PhilOfTheFuture''

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-->--'''Barbara''', -->-- '''Barbara''', ''PhilOfTheFuture''

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