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* ''Manga/MyHeroAcademia'': [[BigBadWannabe Shigaraki's]] own Quirck allows him to gradually disintegrate whatever or whoever he touches with all his fingers. As confirmed near the end of the Overhaul arc, cutting the disintegrated limb is the only way to prevent death. [[spoiler: Much later Re-Destro is forced to amputate his own feet to avoid being turned into dust by Shigaraki's attack.]]
* ''Anime/NeonGenesisEvangelion'': When Eva 0's left arm is infected by angel goo from the possessed Eva 3 Ikari gives the order to amputate the arm remotely, despite Rei's synchronization with it.

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* ''Manga/MyHeroAcademia'': [[BigBadWannabe Shigaraki's]] own Quirck Quirk allows him to gradually disintegrate whatever or whoever he touches with all his fingers. As confirmed near the end of the Overhaul arc, cutting the disintegrated limb is the only way to prevent death. [[spoiler: Much later Re-Destro is forced to amputate his own feet to avoid being turned into dust by Shigaraki's attack.]]
* ''Anime/NeonGenesisEvangelion'': When Eva 0's left arm is infected by angel goo from the possessed Eva 3 3, Ikari gives the order to amputate the arm remotely, despite Rei's synchronization with it.

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* ''Anime/NeonGenesisEvangelion'': When Eva 0's left arm is infected by angel goo from the possessed Eva 3 Ikari gives the order to amputate the arm remotely, despite Rei's synchronization with it.


-->-- ''[[http://www.girlgeniusonline.com/comic.php?date=20060719 Girl Genius]]'' [[note]]Not recommended for people who aren't [[MadeOfIron super-tough]] abominations of science[[/note]]

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-->-- ''[[http://www.girlgeniusonline.com/comic.php?date=20060719 Girl Genius]]'' [[note]]Not recommended for people who aren't [[MadeOfIron super-tough]] abominations of science[[/note]]
''Webcomic/GirlGenius''


->'''Lars:''' You cut [Dimo's] arm off!\\

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->'''Lars:''' You cut [Dimo's] arm his ''arm'' off!\\

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* In ''VideoGame/FrostPunk'', people affected by mild frostbite can be amputated to stop it if you sign the Radical Treatment law, but are unable to work as a result. However, later on you can give them prosthetics to make them useful again.

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* ''Webcomic/LastBlood'': The school principal is lightly grazed on the hand. They decide to amputate his whole arm just to be on the safe side. We never get to see if it worked because one vampire decides it's not worth the risk to find out[[note]]Smelling the symptoms of infection on him with vampire senses didn't elicit a vote of confidence either[[/note]].

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** In Season 4, [[spoiler:A.J. has to amputate Clem's leg to stop a zombie bite.]]

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* ''Manga/MyHeroAcademia'': [[BigBadWannabe Shigaraki's]] own Quirck allows him to gradually disintegrate whatever or whoever he touches with all his fingers. As confirmed near the end of the Overhaul arc, cutting the disintegrated limb is the only way to prevent death. [[spoiler: Much later Re-Destro is forced to amputate his own feet to avoid being turned into dust by Shigaraki's attack.]]

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* In her backstory, Petrushka from ''Manga/GunslingerGirl'' had a leg amputeed due to cancer caused by Chernobyl exposure. She was DrivenToSuicide but [[BungledSuicide survived]] and was turn into a cyborg {{Child Soldier|s}}. The epilogue reveals that she later [[spoiler:died because her cancer came back as leukemia because she wasn't on treatment]].


* In the ''Literature/OldKingdom'' books, this happens twice, first in ''Abhorsen'', when [[spoiler: the Disreputable Dog bites]] off [[spoiler: Lirael's]] hand to save her from the corruption of the Destroyer and prevent her from having to pull a HeroicSacrifice, then in ''Goldenhand'', when Ferin's otherwise treatable arrow wound is constantly aggravated (the undead are not especially considerate about the need for rest-stops) and a Free Magic talisman inside her gets loose, meaning that while she doesn't get 'the blood poison', her foot starts mutating into something horrible.



** In "[[Recap/DoctorWhoS13E6TheSeedsOfDoom The Seeds of Doom]]", after Winlett is infected by the Kyrnoid, the team plans to amputate his arm in the hope that it would maybe slow the infection while they think of something else to try. However, the Kyrnoid takes him over and he escapes before they can do so.

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** In "[[Recap/DoctorWhoS13E6TheSeedsOfDoom The Seeds of Doom]]", after Winlett is infected by the Kyrnoid, Krynoid, the team plans to amputate his arm in the hope that it would maybe slow the infection while they think of something else to try. However, the Kyrnoid takes him over and he escapes before they can do so.

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* Also the recommended course in some cases of advance cancer. In one case the doctors had to [[HalfTheManHeUsedToBe remove the entire lower half of a man to save his life.]] However this wasn't a case of BodyHorror for the man, he actually cried in happiness afterwards because it was so painful.

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* In ''VideoGame/FearAndHunger'', there are enemies which are capable of attacks that can infect the limbs of your party members. While green herbs can cure those infections, bonesaws can also deal with them and should be used as a last resort.


->'''Lars:''' You cut [Dimo's] arm off!
->'''Oggie:''' Um... Dis '''vos''' de right von, yah?
->'''Lars:''' It's '''melting'''!
->'''Oggie:''' Yop. Dot vas it.

to:

->'''Lars:''' You cut [Dimo's] arm off!
->'''Oggie:'''
off!\\
'''Oggie:'''
Um... Dis '''vos''' de right von, yah?
->'''Lars:'''
yah?\\
'''Lars:'''
It's '''melting'''!
->'''Oggie:'''
'''melting'''!\\
'''Oggie:'''
Yop. Dot vas it.






[[folder: Anime and Manga ]]

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[[folder: Anime [[folder:Anime and Manga ]]
Manga]]



* In one of the more infamous scenes from ''Manga/MadeInAbyss'', [[spoiler:Riko has Reg attempt to amputate her arm to stop the spread of a predatory animal's poison]]. [[SubvertedTrope Subverted]], in that this likely would not have worked even if the character performing the amputation hadn't been grossly unqualified.



* In one of the more infamous scenes from ''Manga/MadeInAbyss'', [[spoiler:Riko has Reg attempt to amputate her arm to stop the spread of a predatory animal's poison]]. [[SubvertedTrope Subverted]], in that this likely would not have worked even if the character performing the amputation hadn't been grossly unqualified.



[[folder: Comic Book ]]

* In ''ComicBook/TheThingFromAnotherWorld: Climate of Fear'', a sequel series to ''Film/{{The Thing|1982}}'', [[spoiler: Agapito]] cuts off his arm with a machete to keep himself from being infected.

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[[folder: Comic Book ]]

* In ''ComicBook/TheThingFromAnotherWorld: Climate of Fear'', a sequel series to ''Film/{{The Thing|1982}}'', [[spoiler: Agapito]] cuts off his arm with a machete to keep himself from being infected.
[[folder:Comic Books]]



* In ''ComicBook/TheThingFromAnotherWorld: Climate of Fear'', a sequel series to ''Film/{{The Thing|1982}}'', [[spoiler: Agapito]] cuts off his arm with a machete to keep himself from being infected.






[[folder: FanFiction]]

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[[folder: FanFiction]]
[[folder:Fan Fiction]]



[[folder: Film ]]

* In ''Film/{{Evolution}}'', Dr Block finds himself host to an alien fly that is burrowing into his leg. He refuses to let doctors cut off the leg in question until he learns that it's headed for his testicles. [[spoiler:Ultimately, they pull it out of his rectum instead.]]

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[[folder: Film ]]

[[folder:Film Live-Action]]
* In ''Film/{{Evolution}}'', Dr Block finds himself host to Subverted in ''Film/TheBlob1988''. The homeless man suddenly shows up wielding an alien fly axe, but it turns out that is burrowing into he's trying to hack his leg. He refuses to let doctors cut lower arm off because the leg in question until he learns micro-blob that it's headed for fell from space has started consuming it. Before he can finish, the blob clutches to the limb's remainder to continue eating him.
* Attempted in the second ''Film/CabinFever'' movie, wherein a character gets blood infected with necrotizing fasciitis on
his testicles. [[spoiler:Ultimately, they pull hand and cuts it out of off using the chop saw in his rectum instead.]]school's shop class. ultimately, it doesn't work.



* In ''Film/DayOfTheDead1985'', a soldier is bitten by a zombie, but his arm is immediately amputated and cauterized. It's uncertain if this did any good, as shortly after he wakes up he essentially [[DrivenToSuicide commits suicide by zombie horde anyway]].



* In ''Film/{{District 9}}'' [[spoiler:Wikus]] attempts to chop his arm off in the hope that it will stop the metamorphosis into a Prawn from spreading, but he only manages to get a finger off and stops due to the pain.
* In ''Film/{{Evolution}}'', Dr Block finds himself host to an alien fly that is burrowing into his leg. He refuses to let doctors cut off the leg in question until he learns that it's headed for his testicles. [[spoiler:Ultimately, they pull it out of his rectum instead.]]



* ''Film/PansLabyrinth'': A wounded Spanish rebel is forced to have his gangrenous leg amputated. He insists on a moment to psych himself up before biting the bullet and letting them start cutting.



* Subverted in ''Film/TheBlob1988''. The homeless man suddenly shows up wielding an axe, but it turns out that he's trying to hack his lower arm off because the micro-blob that fell from space has started consuming it. Before he can finish, the blob clutches to the limb's remainder to continue eating him.
* In ''Film/{{District 9}}'' [[spoiler:Wikus]] attempts to chop his arm off in the hope that it will stop the metamorphosis into a Prawn from spreading, but he only manages to get a finger off and stops due to the pain.
* ''Film/PansLabyrinth'': A wounded Spanish rebel is forced to have his gangrenous leg amputated. He insists on a moment to psych himself up before biting the bullet and letting them start cutting.
* Attempted in the second ''Film/CabinFever'' movie, wherein a character gets blood infected with necrotizing fasciitis on his hand and cuts it off using the chop saw in his school's shop class. ultimately, it doesn't work.
* In ''Film/DayOfTheDead1985'', a soldier is bitten by a zombie, but his arm is immediately amputated and cauterized. It's uncertain if this did any good, as shortly after he wakes up he essentially [[DrivenToSuicide commits suicide by zombie horde anyway]].



[[folder: Literature ]]

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[[folder: Literature ]]
[[folder:Literature]]



* In ''Literature/{{Remnants}}'' two of the characters have to have appendages amputated to remove worms that are slowly eating them. One of them is a {{redshirt}}, who bleeds out after his leg is removed. The other is a main character, who only loses a finger.



* The second book in the Creator/TamoraPierce series ''Literature/TheImmortals'' has the mage Gissa, who cuts her own hand off after it gets hit by a drop of the Bloodrain poison potion she was stirring. If she had left it long enough for it to reach her bloodstream it would have rotted her from the inside out; once it reached full strength they were planning on pouring it into the ''river'', killing every living thing within ten miles.
* Discussed in Literature/TheZombieSurvivalGuide, and also averted, as the tract points out that due to the speed of blood flow, the virus is likely spread well past the initial bite before amputation can take place.

to:

* In ''Literature/{{Remnants}}'' two of the characters have to have appendages amputated to remove worms that are slowly eating them. One of them is a {{redshirt}}, who bleeds out after his leg is removed. The other is a main character, who only loses a finger.
* ''Literature/TortallUniverse'':
The second book in the Creator/TamoraPierce series of ''Literature/TheImmortals'' has the mage Gissa, who cuts her own hand off after it gets hit by a drop of the Bloodrain poison potion she was stirring. If she had left it long enough for it to reach her bloodstream it would have rotted her from the inside out; once it reached full strength they were planning on pouring it into the ''river'', killing every living thing within ten miles.
* Discussed in Literature/TheZombieSurvivalGuide, ''Literature/TheZombieSurvivalGuide'', and also averted, as the tract points out that due to the speed of blood flow, the virus is will likely spread well past the initial bite before amputation can take place.
place.



[[folder: Live-Action TV ]]

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[[folder: Live-Action TV ]]
[[folder:Live-Action TV]]
* Attempted in ''Series/AgentsOfSHIELD'''s second season premiere "[[Recap/AgentsOfSHIELDS2E1Shadows Shadows]]", when an alien artifact causes an agent's hand, then arm, to slowly start turning to stone. She demands that her arm be amputated in the hopes of stopping the spread, but she is killed by something else a minute or so later anyway. [[spoiler: The season finale has ''Coulson'' be similarly affected; his hand is almost immediately hacked off to stop the spread, and he does indeed survive]].
* In the series finale of ''Series/{{Copper}}'', which features Morehouse, Corcoran and Freeman out in the Southern wilderness hunting John Wilkes Boothe, Morehouse's [[ArtificialLimbs prosthetic leg]] begins to chafe on his stump, and it eventually becomes infected. For a while, Morehouse attempts to simply ignore it, but after a while the pain from the infection is so great he can barely walk, remarking that his leg "hurts worse than the day [he] lost it." Freeman, a doctor, eventually has to remove the lower part of his stump to stop the gangrene from spreading.
* ''Series/DoctorWho'':
** In "[[Recap/DoctorWhoS13E6TheSeedsOfDoom The Seeds of Doom]]", after Winlett is infected by the Kyrnoid, the team plans to amputate his arm in the hope that it would maybe slow the infection while they think of something else to try. However, the Kyrnoid takes him over and he escapes before they can do so.
** [[Recap/DoctorWhoS37E8TheWitchfinders "The Witchfinders"]]: [[spoiler:After Becka Savage got infected with Morax bio-material, she tried to stop it by having her grandmother chop off her leg. However, her grandmother couldn't bring herself to do it.]]



* ''Series/DoctorWho'': In "[[Recap/DoctorWhoS13E6TheSeedsOfDoom The Seeds of Doom]]", after Winlett is infected by the Kyrnoid, the team plans to amputate his arm in the hope that it would maybe slow the infection while they think of something else to try. However, the Kyrnoid takes him over and he escapes before they can do so.
* In ''Series/TheWalkingDead'' episode "[[{{Recap/TheWalkingDeadS03E01Seed}} Seed]]", they attempt this with [[spoiler: Hershel after he is bitten. It works. Later, they have to do the same thing with Tyreese, but he dies from blood loss.]]

to:

* ''Series/DoctorWho'': In "[[Recap/DoctorWhoS13E6TheSeedsOfDoom The Seeds of Doom]]", ''Series/{{Vikings}}'', after Winlett is infected by the Kyrnoid, the team plans being struck with an arrow in his arm, [[spoiler: Torstein]] asks to amputate his arm in the hope that it would maybe slow because the infection while they think of something else is killing him. Everyone involved, including Torstein, seems to try. However, know it's probably too late for this to do any good and the Kyrnoid takes him over and infection continues getting worse afterward. [[spoiler:Eventually Torstein more or less gives himself a SuicideMission so he escapes before they can do so.
at least have a chance of going to Valhalla]].
* In ''Series/TheWalkingDead'' episode "[[{{Recap/TheWalkingDeadS03E01Seed}} "[[Recap/TheWalkingDeadS03E01Seed Seed]]", they attempt this with [[spoiler: Hershel after he is bitten. It works. Later, they have to do the same thing with Tyreese, but he dies from blood loss.]]



* In the series finale of ''Series/{{Copper}}'', which features Morehouse, Corcoran and Freeman out in the Southern wilderness hunting John Wilkes Boothe, Morehouse's [[ArtificialLimbs prosthetic leg]] begins to chafe on his stump, and it eventually becomes infected. For a while, Morehouse attempts to simply ignore it, but after a while the pain from the infection is so great he can barely walk, remarking that his leg "hurts worse than the day [he] lost it." Freeman, a doctor, eventually has to remove the lower part of his stump to stop the gangrene from spreading.
* Attempted in ''Series/AgentsOfSHIELD'''s second season premier "[[Recap/AgentsOfSHIELDS2E1Shadows Shadows]]", when an alien artifact causes an agent's hand, then arm, to slowly start turning to stone. She demands that her arm be amputated in the hopes of stopping the spread, but she is killed by something else a minute or so later anyway. [[spoiler: The season finale has ''Coulson'' be similarly affected; his hand is almost immediately hacked off to stop the spread, and he does indeed survive]].
* In ''Series/{{Vikings}}'', after being struck with an arrow in his arm, [[spoiler: Torstein]] asks to amputate it because the infection is killing him. Everyone involved, including Torstein, seems to know it's probably too late for this to do any good and the infection continues getting worse afterward. [[spoiler:Eventually Torstein more or less gives himself a SuicideMission so he can at least have a chance of going to Valhalla]].



[[folder: Video Games ]]

* In ''VideoGame/TheWalkingDead'',
** In Season One Episode Five, after [[spoiler: Lee]] is bitten he can try this to stop the infection. [[spoiler: It doesn't work; even if you cut his arm off Lee will still die at the end.]]
** Season Two Episode Three introduces Reggie, whose missing arm proves that someone can be saved from a zombie bite if the amputation happens quickly enough. [[spoiler:At the end of the episode, Clem can opt to do this to Sarita, who gets bitten on the wrist during the escape from Carver's compound. Subverted at the start of Episode 4, when she gets mauled by walkers anyway.]]
* In ''VideoGame/RobinsonsRequiem'', if one of your limbs suffers from gangrene due to not treating an infection, the only way to avoid an agonizing death from poisoning is to cutt off the rotten limb.
* In ''VideoGame/StarcraftIIWingsOfLiberty'' General Warfield takes several hydralisk spines to the arm, if you talk to him afterwards he complains that the medics are having trouble stopping the poison from spreading but won't let him just cut the damn thing off. In the next cutscene he is shown with a large prosthetic arm that features a cannon.

to:

[[folder: Video Games ]]

[[folder:Video Games]]
* In ''VideoGame/TheWalkingDead'',
** In Season One Episode Five, after [[spoiler: Lee]] is bitten he can try this to stop
''VideoGame/GrimFandango'', the infection. [[spoiler: It doesn't work; even if you cut his arm off Lee will still die at the end.]]
** Season Two Episode Three introduces Reggie, whose missing arm proves
spread of Sproutella (a chemical that someone makes the skeletal inhabitants of the afterlife DeaderThanDead by tuning them into flowers) can be saved from a zombie bite if stopped by cutting away the amputation happens quickly enough. [[spoiler:At the end of the episode, Clem can opt to do sprouted parts before it reaches your head. Salvador Limones demonstrates this by using an ax to Sarita, who gets bitten on the wrist during the escape from Carver's compound. Subverted at chop a sprouting soldier in half: he's left with his head, half his torso, and one arm - but survives.
* At
the start of Episode 4, when she gets mauled by walkers anyway.]]
* In ''VideoGame/RobinsonsRequiem'', if one of your limbs suffers from gangrene due to not treating an infection,
''VideoGame/{{Hob}}'', the only way to avoid an agonizing death from poisoning protagonist is to cutt poisoned in their left hand, and the very rapid spread is halted by cutting off the rotten limb.
* In ''VideoGame/StarcraftIIWingsOfLiberty'' General Warfield takes several hydralisk spines to the arm, if you talk to him afterwards he complains that the medics are having trouble stopping the poison from spreading but won't let him just cut the damn thing off. In the next cutscene he
their arm. It is shown subsequently replaced with a large prosthetic arm that features a cannon.an oversized robotic one.



* In ''VideoGame/RobinsonsRequiem'', if one of your limbs suffers from gangrene due to not treating an infection, the only way to avoid an agonizing death from poisoning is to cut off the rotten limb.



* In ''VideoGame/StarcraftIIWingsOfLiberty'' General Warfield takes several hydralisk spines to the arm, if you talk to him afterwards he complains that the medics are having trouble stopping the poison from spreading but won't let him just cut the damn thing off. In the next cutscene he is shown with a large prosthetic arm that features a cannon.



* At the start of ''VideoGame/{{Hob}}'', the protagonist is poisoned in their left hand, and the very rapid spread is halted by cutting off their arm. It is subsequently replaced with an oversized robotic one.
* In ''VideoGame/GrimFandango'', the spread of Sproutella (a chemical that makes the skeletal inhabitants of the afterlife DeaderThanDead by tuning them into flowers) can be stopped by cutting away the sprouted parts before it reaches your head. Salvador Limones demonstrates this by using an ax to chop a sprouting soldier in half: he's left with his head, half his torso, and one arm - but survives.

to:

* At In ''VideoGame/TheWalkingDead'',
** In Season One Episode Five, after [[spoiler: Lee]] is bitten he can try this to stop the infection. [[spoiler: It doesn't work; even if you cut his arm off Lee will still die at the end.]]
** Season Two Episode Three introduces Reggie, whose missing arm proves that someone can be saved from a zombie bite if the amputation happens quickly enough. [[spoiler:At the end of the episode, Clem can opt to do this to Sarita, who gets bitten on the wrist during the escape from Carver's compound. Subverted at
the start of ''VideoGame/{{Hob}}'', the protagonist is poisoned in their left hand, and the very rapid spread is halted Episode 4, when she gets mauled by cutting off their arm. It is subsequently replaced with an oversized robotic one.
* In ''VideoGame/GrimFandango'', the spread of Sproutella (a chemical that makes the skeletal inhabitants of the afterlife DeaderThanDead by tuning them into flowers) can be stopped by cutting away the sprouted parts before it reaches your head. Salvador Limones demonstrates this by using an ax to chop a sprouting soldier in half: he's left with his head, half his torso, and one arm - but survives.
walkers anyway.]]



[[folder: Web Animation ]]

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[[folder: Web Animation ]]
[[folder:Web Animation]]






[[folder: Web Comics ]]

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[[folder: Web Comics ]]
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[[folder: Web Original ]]

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[[folder: Web Original ]]
[[folder:Web Original]]
* ''Podcast/TheAdventureZone'': During the Crystal Kingdom arc, this seems to be the only way to prevent the spreading pink tourmaline from completely crystallizing someone, as Merle unfortunately finds out after grabbing a crystal and Magnus hacks his hand off.



* ''Podcast/TheAdventureZone'': During the Crystal Kingdom arc, this seems to be the only way to prevent the spreading pink tourmaline from completely crystallizing someone, as Merle unfortunately finds out after grabbing a crystal and Magnus hacks his hand off.



[[folder: Western Animation ]]

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[[folder: Western Animation ]]
[[folder:Western Animation]]






[[folder: Real Life ]]

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[[folder: Real Life ]]
[[folder:Real Life]]





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[[folder: Live Action TV ]]

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[[folder: Live Action Live-Action TV ]]



* General Randall in ''Videogame/{{Prototype}}'' hacked off his own arm with a cleaver after being bitten by Elizabeth Greene, fearing that she might have infected him with the Redlight Virus.

to:

* General Randall in ''Videogame/{{Prototype}}'' ''VideoGame/{{Prototype}}'' hacked off his own arm with a cleaver after being bitten by Elizabeth Greene, fearing that she might have infected him with the Redlight Virus.




to:

* In ''VideoGame/GrimFandango'', the spread of Sproutella (a chemical that makes the skeletal inhabitants of the afterlife DeaderThanDead by tuning them into flowers) can be stopped by cutting away the sprouted parts before it reaches your head. Salvador Limones demonstrates this by using an ax to chop a sprouting soldier in half: he's left with his head, half his torso, and one arm - but survives.


* At the start of ''VideoGame/{{Hob}}'', the protagonist is poison in their left hand, and the very rapid spread is halted by cutting off their arm. It is subsequently replaced with an oversized robotic one.

to:

* At the start of ''VideoGame/{{Hob}}'', the protagonist is poison poisoned in their left hand, and the very rapid spread is halted by cutting off their arm. It is subsequently replaced with an oversized robotic one.

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