History GRatedDrug / WesternAnimation

** In the episode "[[Recap/EdEddNEddyS1E4OverYourEd Over Your Ed]]", the Eds are making energy drinks to sell to the customers for Eddy's latest scam, and Eddy just pours a large bag of sugar into the mix when Edd isn't looking. When Edd takes a sample, he spends the rest of the episode hopped up on a sugar rush, acting much more cheerful and manic than usual. By the end of the episode, Edd is even shown to be "hung over", wearing an ice-pack on his head and everything.

* ''WesternAnimation/AvatarTheLastAirbender'': Sokka (and [[TeamPet Momo]]) are high on cactus juice through almost the entirety of "[[Recap/AvatarTheLastAirbenderTheDesert The Desert]]". This is actually TruthInTelevision: there is a type of cactus (peyote) that causes hallucinations if it's eaten.

* ''WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius'': In the episode "Krunch Time", Jimmy attempts to create the perfect candy. When he succeeds, everyone else aside from Jimmy, who didn't have a piece, becomes quickly addicted to the stuff. At first, Jimmy is willing to take advantage of the situation to get favors in exchange for candy, but as they start get increasingly agressive and hooked on the stuff, Jimmy begins to realize how unhealthily it's affecting them, especially when his own parents get addicted too. Trying to cut them off cold leads the citizens of Retroville to riot, willing to imprison Jimmy to frce him to make more candy for them. It's only when Jimmy adds some edible miniturized shock rays to the candy does he break them out of it, figuring the pain would override their pleasure. It works, though [[TheDitz Sheen]] keeps eating more anyways.

* ''WesternAnimation/MeninBlack:TheSeries'': Coffee is this for the worms. Their obsession with the beverage has made them do a lot of foolish things throughout the series, including draining cooling water from a nuclear reactor just to make a pot.

** In the episode "Over Your Ed", the Eds are making energy drinks to sell to the customers for Eddy's latest scam, and Eddy just pours a large bag of sugar into the mix when Edd isn't looking. When Edd takes a sample, he spends the rest of the episode hopped up on a sugar rush, acting much more cheerful and manic than usual. By the end of the episode, Edd is even shown to be "hung over", wearing an ice-pack on his head and everything.

** In "[[Recap/TheSimpsonsS19E12LoveSpringfieldianStyle Love, Springfieldian Style]]", Lisa as Nancy Spuggen and Nelson as Music/SidVicious get hooked on chocolate as if it were cocaine or heroine. Their chocolate spree involves them snorting lines, cooking (melting chocolate powder on spoons), and [[FlushTheEvidence flushing chocolate bars down the toilet]].

** Mac gets hyperactive when he eats sugar. In an episode where Bloo throws a massive rave at Foster's, Mac unwillingly ingests sugar, then proceeds to go through a climbing-the-walls-nude drug trip from the effects. The post-rush withdrawal reduces him to a shivering wreck that's equal parts jonesing junkie and Gollum parody.
** The episode "Cookie Dough" has Frankie devour thousands of boxes of her grandmother's cookies, which she has loved since she was a baby.

* ''WesternAnimation/TheAdventuresofJimmyNeutronBoyGenius'': in the episode "Krunch Time", Jimmy attempts to create the perfect candy. When he succeeds, everyone else aside from Jimmy, who didn't have a piece, becomes quickly addicted to the stuff. At first, Jimmy is willing to take advantage of the situation to get favors in exchange for candy, but as they start get increasingly agressive and hooked on the stuff, Jimmy begins to realize how unhealthily it's affecting them, especially when his own parents get addicted too. Trying to cut them off cold leads the citizens of Retroville to riot, willing to imprison Jimmy to frce him to make more candy for them. It's only when Jimmy adds some edible miniturized shock rays to the candy does he break them out of it, figuring the pain would override their pleasure. It works, though [[TheDitz Sheen]] keeps eating more anyways.
-->'''Sheen''': Hey, Jimmy, that last batch was delicious! (zap!) Also incredibly painful. (zap!) Hey, do you guys smell smoke? (zap!) (starts patting his face) I can't feel my face! (zap!) How come everything looks blue? (zap!)
* ''WesternAnimation/TheAmazingWorldOfGumball'':
** In "The Flakers", Richard spends most of the episode high on anesthetics from the dentist, experiencing [[MushroomSamba vivid hallucinations]], [[ArtisticLicensePharmacology even though real dental anesthetics are not hallucinogenic]].
** In "The Flower", Mr. Small drinks herbal tea that makes him act completely stoned, zone out, and even pass out. At one point, his eyes dilate while he lets out a "Woo hoo!"

** One episode has Steve get addicted to a energy drink called "Cougar Boost" and he starts acting like a twitchy junkie if he doesn't have any.

* ''WesternAnimation/AvatarTheLastAirbender'' has an episode where Sokka (and [[TeamPet Momo]]) are high on cactus juice almost the entire time. This is actually TruthInTelevision: there is a type of cactus (peyote) that causes hallucinations if it's eaten.

** In "Hooked Up" the villain Spellbinder opens a VR arcade, where people can experience their greatest fantasies. The massive doses of endorphins released by living out these fantasies, however, make these simulators ''extremely'' addictive. As soon as people leave his VR machines, they experience intense withdrawal symptoms. He uses this to get people to steal and commit other crimes for him.
** "The Winning Edge" is actually an aversion of the "G-rated" part as it features ''steroids'' (a "steroidal compound" according to Bruce Wayne's files on it) taken like nicotine patches via adhesive pads called "slappers." [[spoiler: It turns out they're based on Bane's Venom, which has rendered him a comatose junkie and invalid after decades of abuse]]. Terry was accused by his mother of taking the drug, but the test results proved he was clean. To be fair, though, he only swiped a sample to investigate and shut down the source as Batman, and was only in trouble because his little brother was prying.
* Renuyu from ''WesternAnimation/BatmanTheAnimatedSeries''. Matt Hagen is shown to be violent and irritable when he runs out of it, and a goon seems to explicitly liken him to a drug addict, saying "Once they're hooked, they ''stay'' hooked." There's also the obvious subtext of [[DoesThisRemindYouOfAnything Matt becoming so desperate that he agrees to perform increasingly shady and illegal acts just to get more of it]]. Since the purpose of the drug is to cover up Matt Hagen's deformity and make him able to work in show business, it combines drug addiction with plastic surgery addiction.

* ''WesternAnimation/BobsBurgers'': Tina's addiction to coffee in "The Unnatural" is treated like this, with Tina adopting an aggressive new personality and experiencing vivid hallucinations when she goes into withdrawal.
* ''WesternAnimation/TheBoondocks'' episode "The Itis" highlights the destructive effects of too much junk food (soul food) on the neighborhood and its citizens, such as people neglecting their jobs before eventually losing them, becoming morbidly obese, committing crimes to afford their sustenance, the infrastructures falling apart...
* Mira Nova from ''WesternAnimation/BuzzLightyearOfStarCommand'' gains a power boost after absorbing nuclear energy in "Super Nova", but becomes addicted to it over time. Zurg attempted to exploit this, and weaponize the power boost, but that fortunately failed. Her father reveals that he's struggled with this addiction as well. She does get better in the end, but he warns her that in fact, [[SurprisinglyRealisticOutcome she will never be completely free of the cravings for it.]]
* ''WesternAnimation/CaptainPlanetAndThePlaneteers'': '[[DarkerAndEdgier Bleeesss]]...I ''NEED'' Bleeesss...' It's explicitly called "a new designer drug" and kills a person who overdoses on it.

* ''WesternAnimation/CloneHigh'' parodies this in an episode revolving around Abe's destructive addiction to smoking ''raisins''. After learning that you can't actually get high on raisins, the students decide to kick the habit for good and "[[SpoofAesop smoke crack, instead]]!"

* In ''WesternAnimation/CodenameKidsNextDoor'', Numbuh 2 was once a chocolate sauce addict; he claims he's "off the sauce" in "Operation: S.P.A.N.K.E.N.S.T.I.N.E.", but the end suggests he might have relapsed.

* Root beer is often used in place of beer in 1990s Television programs. In the ''WesternAnimation/DextersLaboratory'' episode "Dexter's Rival", in the end, Dexter has a toast with one of his inventions in which he pours root beer in a glass that's usually used for drinking liquor.
** Also, another episode "Beard to be Feared" has Dexter getting roped into breaking up a band of ''flour'' smugglers.
** Shows with an "Old West" setting will substitute sarsaparilla, a broadly similar drink that was popular at the time but has fallen out of fashion.
* The ''WesternAnimation/DoubleDragon1993'' cartoon series, notable for having AnAesop at the end of every episode, had an episode that focused on the Shadow Master producing a designer drug, known as Euphoria, which turned users into wide-eyed, green-eyed zombified people. Presumably in attempt to avoid portraying real drug abuse methods, the green liquid Euphoria was not ingested nor injected, but rather poured onto bare skin, though it was often applied this way to the forearm. Later on, the Shadow Master was back in the business, selling RPM.[[note]]Stored in glass balls, they were broken and the drug inhaled.[[/note]] Billy looked ''horrible'' when forcibly dosed. The drug acted very much like steroids.
* An episode of Disney's ''WesternAnimation/{{Doug}}'' centered on Nic-Nacs, a legal, gum-like "relaxant" that was clearly tobacco in all but name (its main ingredient was "nicoglutenousmonopexterate"). The episode was a pretty heavy-handed screed against the tobacco industry for a kids' show.
** That episode also featured [[JerkAss Mr. Bluff]] knowingly and intentionally marketing that product to kids, therefore cementing his status as a CorruptCorporateExecutive.
* In the ''WesternAnimation/EdEddNEddy'' episode "Over Your Ed", the Eds are making energy drinks to sell to the customers for Eddy's latest scam, and Eddy just pours a large bag of sugar into the mix when Edd isn't looking. When Edd takes a sample, he spends the rest of the episode hopped up on a sugar rush, acting much more cheerful and manic than usual. By the end of the episode, Edd is even shown to be "hung over", wearing an ice-pack on his head and everything.

** In "I Take Thee Quagmire", Stewie became hopelessly addicted to his mother's breast milk. Lois tries to wean him, and he actually kicks the habit, but because of her engorged, painful breasts and missing the closeness breast-feeding offers, she soon hooks him again. TruthInTelevision; ask any nursing mother.
** In "Love Thy Trophy", Stewie gets addicted to a diner's pancakes so much that, when Child Services comes when hearing of Meg's lie about Stewie being her crack-addicted baby, his obsessive behavior only seems to confirm their suspicions. Finally, in TheStinger, he starts to go through a withdrawal process and begins hallucinating a la ''Film/{{Trainspotting}}''.

** The episode "Hell Is Other Robots" has Bender get addicted to electricity, which leads to the first appearance of the "Fry-fro", a funny hairstyle Fry gets on occasion. After an intervention, the main plot plays out when Bender decides to convert to a robot religion.
** Lampshaded in a later episode, where Bender tries electricity again and gets arrested for "possession of something analogous to drugs".
** "The Butterjunk Effect" has this in the form of a nectar found on Kif's home planet, which acts like steroids, including the deepening of one's voice. Leela and Amy began to use nectar to win in Butterfly Derby matches, but it makes them meaner, especially towards Fry and Kif. It also makes them attracted to Fry after a vicious, giant butterfly [[ItMakesSenseInContext sprays him with its butterjunk]].
** ''Futurama'' also features Slurm, whose tagline is "It's highly addictive!" Fry is shown to be extremely addicted to Slurm - even after he finds out what it's made of. When going more than twenty minutes without a Slurm he starts to twitch and get shakes. It doesn't help that he's tasted the super-addictive Super-Slurm.
** Apparently there are no bad drugs in that time. Hermes smokes pot (and doesn't lose it when his young son steals a "cigar" and smokes it). Crack is sold in vending machines, as well as crack mansions. Robots are fueled by alcohol. Bender becomes Iron Cook/Zinc Saucier by (unknowingly) dosing the meal with large amounts of LSD; once the Professor analyzes the liquid, Bender offers to cook a meal knowingly dosed, and everyone accepts eagerly.
*** Interestingly, since Bender runs on alcohol, he gets drunk when he ''doesn't'' drink for a while!

* In ''WesternAnimation/GIJoeARealAmericanHero'', in "The Greatest Evil", Spark is a deadly drug peddled by Headman. Even Falcon and the sister of a Crimson Guard gets caught up in it. Thanks to the efforts of G.I. Joe's Drug Enforcement Force, Headman was finally confronted, and died from a taste of, or rather, a massive overdose of his own medicine.
* ''WesternAnimation/GravityFalls'' had "Smile Dip", a banned German confectionery (and a parody of the real life candy Fun Dip) that caused Mabel to hallucinate. Although, eating [[EleventyZillion bleven-teen]] packages of it probably didn't help matters either.
** In the short "Mabel's Guide To Color", Grenda reveals that drinking expired milk has this effect on her, since it makes her see rainbows.

* ''WesternAnimation/{{Kaeloo}}'': Quack Quack's yogurt. Without it, he undergoes withdrawal symptoms, and in one episode, everybody accuses him of cheating in an athletic event because he was eating yogurt.

* In the '90s ''WesternAnimation/MegaManRubySpears'' cartoon, the meteor fragments in Red Gulch (as seen in "Showdown at Red Gulch") were this to robots.

* ''Westernanimation/PepperAnn'' once had the title character getting obsessed with [[Toys/BeanieBabies Baggy Bean Buddies]], getting dirty and disheveled while selling her things for money to buy them. Turns out she's not the only one, as there's a help group for fellow addicts.

* ''WesternAnimation/ThePowerpuffGirls'':
** There are a couple of examples, both played surprisingly somber and serious for the show, in that the substances themselves might be goofy or fantastical, but the ''consequences'' are appropriately dire. In one episode Mojo Jojo offers [[FiveTokenBand four diverse kids]] from the Girls' class temporary superpowers from a Chemical X knockoff. Before long they are willing to [[spoiler:kill the Powerpuff Girls]] for the next fix.
** In the episode "Candy is Dandy" where the mayor starts rewarding the girls with candy for their heroics, not only is the effect disturbingly similar to a drug high, but the Girls are also willing to abandon their morals to get more: first they strike a deal with Mojo Jojo and repeatedly break him out of prison so that they could arrest him and get candy. When Mojo reneges on the deal and steals the candy instead ForTheEvulz, the Girls literally ''beat him to within an inch of his life.'' [[MyGodWhatHaveIDone This is the point the girls realize how badly their addiction has affected them]].
* In the world of ''WesternAnimation/RegularShow'', soda acts like beer, donuts may be dangerous, and coffee...

* In ''WesternAnimation/{{Sixteen}}'s'' "Over Exposed", Jude becomes addicted to [[BurgerFool Burger McFlipster's]] French Fries. He ends up with a major BalloonBelly and nausea in the end.
* ''WesternAnimation/TheSmoggies'' had purple silly sauce, which was a G-Rated Drug powerful enough to contaminate an eco system and cause whomever came into contact with it to involuntarily sing and dance perpetually, even in diluted amounts. The song they would sing, "The Purple Rag" was an EarWorm as well as being a state of AndIMustScream.
* ''WesternAnimation/SouthPark'' has had episodes based around people getting high on DXM[[labelnote:note]]that means cough syrup; [[https://en.wikipedia.org/wiki/DXM you can]] [[https://www.erowid.org/chemicals/dxm/faq/dxm_faq.shtml get high]] [[https://psychonautwiki.org/wiki/DXM off it]]. If you buy it mixed with [[https://psychonautwiki.org/wiki/DPH DPH]], you'll get some really nasty hallucinations; if you buy it mixed with other chemicals such as acetaminophen, and ingest enough to get high, the additional chemicals can kill you[[/labelnote]] ("Quest for Ratings") and cat urine ("Major Boobage"), and in another episode, Cartman snorts the skin off of illegally-obtained KFC ("Medicinal Fried Chicken"). "Medicinal Fried Chicken" additionally has a story where many of the male adults deliberately get testicular cancer so they can smoke all the medical marijuana they want.

* The ''WesternAnimation/SpongeBobSquarePants'' episode "Cuddle E. Hugs". [=SpongeBob=] eats a moldy Krabby Patty and meets a fluffy, smiley, and Disney-esque hamster, but he is initially the only one who is able to see him. In an attempt to prove that he is real, they give all of [=SpongeBob=]'s friends (except Squidward) pieces of said Krabby Patty. [[spoiler:Cuddle E. Hugs then proceeds to eat everyone who can see him]].
** To be fair, Krabby Patties can be considered as these. For starters, they are very fattening, and eating many of them would give anyone an heart attack or they would go right to their thighs and literally explode. Inversely, if someone doesn’t get a Krabby Patty for a great amount of time, not only they would go on withdrawal, but they would tear the entire city apart, to the point of creating an apocalyptic setting.
* There was an episode of ''WesternAnimation/StaticShock'' featuring a Bang Baby with the ability to give other people super powers temporarily...at the price of not telling anyone where they got them; oh, and they have to steal stuff for him. Well, if you want to get high -- uh, get super powers...

** ComicBook/{{Superboy}}'s addiction to "Shields" (patches developed by ComicBook/LexLuthor that give him access to Kryptonian-level abilities) is also treated like a metaphor for drug abuse. The whole subplot comes off like a cautionary tale about the dangers of steroids.

** There is also the episode where Stan gets addicted to burn cream. More accurately, he needed to apply the cream to a burn on his penis and misunderstood his doctor's directions. This led to him [[ADateWithRosiePalms masturbating for the first time in his life]]. His addiction was actually towards masturbating and using the application of the cream as an excuse to do it without him considering it a sin. Once he ran out of cream refills he eventually performed the act as is.

** In the short "Mabel's Guide To Color", Grenda reveals that drinking [[Squick expired milk]] has this effect on her, since it makes her see rainbows.

** In the short "Mabel's Guide To Color", Grenda reveals that drinking [[Squick expired milk] has this effect on her, since it makes her see rainbows.

* An episode of ''WesternAnimation/{{Arthur}}'' featured a popular candy bar that's later subverted when it's revealed to contain not only ''radioactive elements'', a fictional chemical known as Tri-Enzomated Zorn Jelly which works like a real drug (directly affecting the brain chemistry to make the person consuming the candy bar extremely happy but making the consumer feel sad when the chemical wears off until they get more of it) and the in-show explanation on how said chemical works sounds like an extremely simplified way of explaining how real drugs work. [[SurprisinglyRealisticOutcome This discovery prompts the candy to become illegal]].

* The ''WesternAnimation/DoubleDragon'' cartoon series, notable for having AnAesop at the end of every episode, had an episode that focused on the Shadow Master producing a designer drug, known as Euphoria, which turned users into wide-eyed, green-eyed zombified people. Presumably in attempt to avoid portraying real drug abuse methods, the green liquid Euphoria was not ingested nor injected, but rather poured onto bare skin, though it was often applied this way to the forearm. Later on, the Shadow Master was back in the business, selling RPM.[[note]]Stored in glass balls, they were broken and the drug inhaled.[[/note]] Billy looked ''horrible'' when forcibly dosed. The drug acted very much like steroids.

** In the episode "Candy is Dandy" where the mayor starts rewarding the girls with candy for their heroics, not only is the effect disturbingly similar to a drug high, but the Girls are also willing to abandon their morals to get more: first they strike a deal with Mojo Jojo and repeatedly break him out of prison so that they could arrest him and get candy. When Mojo reneges on the deal and steals the candy instead ForTheEvulz, the Girls literally ''beat him to within an inch of his life.'' [[MyGodWhatHaveIDone This is the point the girls realize how badly their addiction has affected them]]

* In the '90s ''WesternAnimation/MegaMan'' cartoon, the meteor fragments in Red Gulch (as seen in "Showdown at Red Gulch") were this to robots.

* In ''WesternAnimation/TeenTitans'', Cyborg becomes addicted to the power that a new processor has given him, allowing him to do more things in a day than possible. However, when faced with the multiplying enemy named Billy Numerous, Cyborg ends up draining his internal systems and using the Titan Tower's own power supply to keep his processor functioning, which ultimately leads to a system crash that forced his teammates to remove the new processor.

* ''WesternAnimation/YoungJustice''

** The episode "[[Recap/MyLittlePonyFriendshipIsMagicS2E17HeartsAndHoovesDay Hearts and Hooves Day]]" has the love poison. After Big Macintosh and Cheerilee drink some, they become obsessed with one another and call each other [[TastesLikeDiabetes increasingly sickening pet names]]. Doesn't help that the Cutie Mark Crusaders serve it to them in shot glasses and it makes them both [[AlcoholHic hiccup]] after they drink it.

* The ''WesternAnimation/SpongeBobSquarePants'' episode "Cuddle E. Hugs". [=SpongeBob=] eats a moldy Krabby Patty and meets a [[TastesLikeDiabetes fluffy, smiley, and Disney-esque]] hamster, but he is initially the only one who is able to see him. In an attempt to prove that he is real, they give all of [=SpongeBob=]'s friends (except Squidward) pieces of said Krabby Patty. [[spoiler:Cuddle E. Hugs then proceeds to eat everyone who can see him]].

** To be fair, Krabby Patties can be considered as these. For starters, they are very fattening, and eating many of them would give anyone an heart attack or they would go right to their tights and literally explode. Inversely, if someone doesn’t get a Krabby Patty for a great amount of time, not only they would go on withdrawal, but they would tear the entire city apart, to the point of creating an apocalyptic setting.

** Numbuh 5 is implied to be a sugar addict. Her solo episodes are usually themed around candy and hunting for it against a rival. She has a secret stash of candy, has (albeit accidentally) gotten pseudo-high off coffee, and once passed out due to **drinking** several pounds of straight sugar! Numbuh 5's DistaffCounterpart rival, Heinrich von Marzipan, also seems to have an addiction and handles it far worse than the former.

* ''WesternAnimation/TheAmazingWorldOfGumball'': In "The Flakers", Richard spends most of the episode high on anesthetics from the dentist, experiencing [[MushroomSamba vivid hallucinations]], [[ArtisticLicensePharmacology even though real dental anesthetics are not hallucinogenic]].

* An episode of ''WesternAnimation/TheLooneyTunesShow'' has Bugs Bunny addicted to Spargle, an energy drink he acquires from Yosemite Sam. He is extremely hyper, euphoric and over-productive when he consumes large amounts of it and freaks out when his supply runs out to the point of threatening Sam for more. [[spoiler:Subverted when it turns out that Sparkle's secret ingredient ''is'' an illegal drug.]]
** Another episode has Bugs getting addicted to Porky's catering, after the latter switches to his grandmother's high in butter recipes. Bugs becomes obsessed with getting his hands on more of Porky's cooking and wastes a lot of money hosting parties with random strangers pulled off the streets. Even the other characters try to warn Bugs eating too much of that stuff isn't healthy, pointing out he's steadily growing fat until he gets humongous and Porky cuts him off. [[spoiler:Bugs manages to kick the habit after he empties an entire swimming pool jumping to save Daffy from drowning.]]