History Funny / TheBindingOfIsaac

* The trailer for Repentance is basically Awesome all the way, but in one instance, as it flaunts the game having MORE ENEMIES, MORE ITEMS, MORE ROOMS, MORE ACHIEVEMENTS, it suddenly drops ''MORE POOP''!
* Tainted Jacob's gimmick is that [[StalkedByTheBell after a given amount of time passes, the wretched spirit of Esau will rise from Hell]] and begin relentlessly chasing Jacob, hellbent on killing him. It's a tense and difficult mechanic to play around, but you can also foil Esau ''permanently'' by... [[CessationOfExistence throwing an eraser at him.]] [[NotMakingThisUpDisclaimer Yes, you read that right.]] The vengeful soul of Jacob's brother can be easily vanquished... by an eraser to the face. And no, he doesn't even get DraggedOffToHell by Big Horn like he usually does - he just straight up vanishes.

** Taking three Puberty pills gives the "adult" transformation, which is just a free health-up... but also gives Isaac some scraggly facial hair. This applies on ALL characters, including [[BeardedLady female ones]].

* Once Isaac dispatches the first three of the Ultra forms of TheFourHorsemenOfTheApocalypse in the TrueFinalBoss ([[CapcomSequelStagnation we promise. Honest!]]), Death has a very understandably frustrated FacePalm. It is quite amusing to see arguably the scariest of the four [[YouHaveGotToBeKiddingMe getting annoyed that his brethren just got killed by a naked child.]]

** Also the fact that they only appear in Gehenna, of all places. You fight your way through a bloodstained Satanic temple filled with depraved cultists only to come across one of the silliest bosses in the game.
* The Reverse arcana Tarot Cards are an interesting lot, having effects that are either the opposite of the original card, or behave in the spirit of that opposite. Death Reversed turns two enemies in the room into charmed skeletons, Temperence Reversed causes Isaac to eat five random pills, etc. But Tower Reversed has among the most outlandish interpretations of this; instead of dropping several bombs into the room and destroying most rocks and pots in it, the card causes ''reverse explosions'' that will ''create'' rocks and pots in a way that leaves the exits unobstructed.
** Reversed High Priestess also deserves a mention. When you pick it up, the description is a brief [[OhCrap "Run."]]. Queue Isaac being barraged by an onslaught of Mom stomps for a solid minute.

!Per wiki policy, Administrivia/SpoilersOff applies here and all spoilers are unmarked. Administrivia/YouHaveBeenWarned.

* Tainted Jacob's gimmick is that [[StalkedByTheBell after a given amount of time passes, the wretched spirit of Esau will rise from Hell]] and begin relentlessly chasing Jacob, hellbent on killing him. It's a tense and difficult mechanic to play around, but you can also foil Esau ''permanently'' by... [[CessationOfExistence throwing an eraser at him.]]

* The trailer for Repentance is basically Awesome all the way, but in one instance, as it flaunts the game having MORE ENEMIES, MORE ITEMS, MORE ROOMS, MORE ACHIEVEMENTS, it suddenly drops ''MORE POOP''!

* The trailer for Repentance is basically Awesome all the way, but in one instance, as it flaunts the game having MORE ENEMIES, MORE ITEMS, MORE ROOMS, MORE ACHIEVEMENTS, it suddenly drops ''MORE POOP''!
* ''Repentance'' added a few level transition cutscenes. One of them shows Isaac looking at clouds, then getting surprised. Because the cloud changed to resemble a hand FlippingTheBird at him. Sums up his life pretty well. Another cutscene has Isaac thinking of himself in his usual TroubledFetalPosition, then the Isaac inside the thought bubble has another thought bubble showing ''another'' Isaac, and ''that'' Isaac has ''another'' thought bubble...

* The trailer for Repentance is basically Awesome all the way, but in one instance, as it flaunts the game having MORE ENEMIES, MORE ITEMS, MORE ROOMS, MORE ACHIEVEMENTS, it suddenly drops ''MORE POOP''!

* During the second phase of the Dogma battle, there are preachers in the background rambling and ranting verses of the Bible and the way they say their lines is such a over the top way that you cant help but laugh even in spite of Dogma being a KnightOfCerebus.

* During the second phase of the Dogma battle, there are preachers in the background rambling and ranting verses of the Bible and the way they say their lines is such a over the top way that you cant help but laugh even in spite of Domga being a KnightOfCerebus.

* In the event that 700+ items isn't enough variety for the player, ''Repentance'' introduces "Glitch Items" that are found from TMTRAINER or have a chance to be in Secret and ERROR Rooms after beating Delirium with Tainted Eden. They can do ''anything,'' to the point of some downright absurd effects, [[https://old.reddit.com/r/bindingofisaac/comments/mj0xv9/the_binding_of_isaac_repentance_delete_this/ such as replacing fireplaces with End Chests and allowing the run to be ended in fifteen seconds.]] The DELETE THIS challenge has the player start the run with TMTRAINER and go all the way to ???, ensuing a chaotic run.

* During the second phase of the Dogma battle, there are preachers in the background rambling and ranting verses of the Bible and the way they say their lines is such a over the top way that you cant help but laugh even in spite of Domga being a KnightOfCerberus.

* During the second phase of the Dogma battle, there are preachers in the background rambling and ranting verses of the Bible and the way they say their lines is such a over the top way that you cant help but laugh even in spite of Domga being a Knight of Cerberus.

* What do you get when you cross Loki and Hornfel and someone insane enough to stich them together? You get the Horny Boys, one of the funniest bosses made for Isaac yet.

* What do you get when you cross Loki and Hornfel and someone insane enough to stich them together? You get the Horny Boy, one of the funniest bosses made for Isaac yet.

* During the second phase of the Dogma battle, there are preachers in the background rambling and ranting verses of the Bible and the way they say their lines is such a over the top way that you cant help but laugh even in spite of Domga being a Knight of Cerbrus.

* An addition made in ''Repentance'' is Horse Pills; Larger pills that grant exaggerated versions of the typical effects; Good becomes great, bad becomes worse, and [[LargeHam the narrator is more hammy]]. This is applied to almost every pill in the game... including the already funny "I Found Pills", which causes Isaac's face to morph into a horse's grin while the narrator screams "I FOUND '''PILLS!'''" at the top of his lungs.

* An addition made in ''Repentance'' is Horse Pills; Larger pills that grant exaggerated versions of the typical effects; Good becomes great, bad becomes worse, and the narrator gets louder. This is applied to almost every pill in the game... including "I Found Pills", which causes Isaac's face to morph into a horse's grin while the narrator screams "I FOUND '''PILLS!'''" at the top of his lungs.

* Once Isaac dispatches the first three of the Ultra forms of TheFourHorsemenOfTheApocalypse in the TrueFinalBoss ([[CapcomSequelStagnation we promise. Honest!]])), Death has a very understandably frustrated FacePalm. It is quite amusing to see arguably the scariest of the four [[YouHaveGotToBeKiddingMe getting annoyed that his brethren just got killed by a naked child.]]

* On another note, due to the way synergies work, your tears change shape, color, and size. [[BreathWeapon Brim]][[BloodyMurder stone]] results in a good-sized blood beam fired from the mouth, as an example... but you get Number One, it turns yellow. Yes, your character goes from firing blood lasers to firing ''pee lasers''. [[{{Squick}} From the mouth, too.]]

** As another rung to how goofy Sloth is, Edmund would later confirm that the Bob items and transformation are in fact referring to Sloth by his first name. In addition, this mean that Sloth finally gets a unique sprite set due to the Bob transformation... and then he can't be bothered to use it.