History Fridge / CellsAtWork

* In the beginning of Episode 4 Eosinophil is fighting a germ with a spiral-shaped lower torso and tendrils for arms, and a spiral-shaped appendage on its head. While the bacterium is not named, it bears a notable resemblance to a ''spirochete'', a coiled bacterium known for causing diseases such as Lyme disease and leptospirosis.

** Forget about simple autoimmunity for a moment. Remember that White Blood Cells and T Cells are sentient on this world, as with the other cells. Even most viruses and bacteria are more or less humanoid, or at the very least are sentient enought to talk. With that in mind: ''[[DemonicPossession How would an HIV infection look like]] [[FateWorseThanDeath from a T Cell's perspective?]]''

* Episode 6 shows a young [=AE3803=] as an erythroblast being chased by a Pseudomona. Except they are in the bone marrow at the time, which means the poor person has had none marrow infection which is very serious.

** Forget about simple autoimmunity for a moment. Remember that White Blood Cells and T Cells are sentient on this world, as with the other cells. Even most viruses and bacteria are more or less humanoid or are sentient enought to talk. With that in mind: ''[[DemonicPossession How would an HIV infection look like]] [[AndIMustScream from a T Cell's perspective?]]''

** Forget about simple autoimminity for a moment. Remember that White Blood Cells and T Cells are sentient on this world, as with the other cells. Even most viruses and bacteria are more or less humanoid. With that in mind: ''[[DemonicPossession How would an HIV infection look like]] [[AndIMustScream from a T Cell's perspective?]]''

* Enucleation of immature RBCS is depicted as the removal of a bobble on top of their hat, but since a nucleus is more like a heart of a cell...

* Denucleation of immature RBCS is depicted as the removal of a bobble on top of their hat, but since a nucleus is more like a heart of a cell...
** In Cells at Work Black, one red blood cell even mentions how their "organelles were removed to carry hemoglobin." Did they literally have their equivalents of hearts ripped out and the cavity filled with even more "blood"?

** It's not mentioned in the anime or the manga, but it's not just Neutrophils that have P-selectin. Many other kinds of immune cells, such as Eosinophils, have it too.

* With cells as people, how many cell deaths are glossed over in the series? Realistically, red blood cells in a scab eventually die as they dry up, neutrophils that consume too many germs eventually self destruct, and platelets are eventually consumed by leukocytes once their job is finished. And let's not forget how individual cells have life spans measured in days...

* In the main series, the Red Blood Cells are coed, but rather than simply {{gender flip}}ping them in ''BLACK'', the squad is all men. There's a good chance that the main series host body actually has AB type blood, with As and Bs treated as separate genders. Of course, this becomes a bit problematic when one remembers about the lack of antigens making a person have O-type blood, and doesn't help with determining more with how RH factors for Erythrocytes can be a thing, depending on whether your blood is positive or negative. this gets further elaborated on in the Fridge Logic section.

** Excluding traumatic death by bacteria or scrape wound, or being in ''BLACK'', cells which reach the end of their normal biological lifespans return to the bone marrow to have their clothes and equipment changed. The cells have also been shown to have days off, or other jobs, such as the Platelets sweeping up the leaves from the Dendritic cells' offices.

* While bacteria are presented as evil villains and larger multicellular parasites as {{kaiju}}, the viruses are shown as inert "hats" that turn people into zombies...because biologically speaking, viruses aren't actually alive at all, just infectious particles!

** Testosterone and estrogen are both present simultaneously in a human body, regardless of the gender, just in different amounts which does determine it. Aka, the cell population in a woman would be mostly "feminine" while in a man, it would be mostly "masculine". Nothing strange here.

* In the main series, the Red Blood Cells are coed, but rather than simply {{gender flip}}ping them in ''BLACK'', the squad is all men. There's a good chance that the main series host body actually has AB type blood, with As and Bs treated as separate genders. Of course, this becomes a bit problematic when one remembers about the lack of antigens making a person have O-type blood, and doesn't help with determining more with how RH factors for Erythrocytes can be a thing, depending on whether your blood is positive or negative.

* In the main series, the Red Blood Cells are coed, but rather than simply {{gender flip}}ping them in ''BLACK'', the squad is all men. There's a good chance that the main series host body actually has AB type blood, with As and Bs treated as separate genders.

** Excluding traumatic death by bacteria or scrape wound, or being in ''BLACK'', cells which reach the end of their normal biological lifespans return to the bone marrow to have their clothes and equipment changed. The cells have also been shown to have days off, or other jobs, such as the Platelets sweeping up the leaves from the Dendritic cells offices.

** Testosterone and estrogen are both present simultaneously in a human body, regardless of the gender, just in different amounts which does determines it. Aka, the cell population in a woman would be mostly "feminine" while in a man, it would be mostly "masculine". Nothing strange here.

[[folder: Fridge Brilliance]]

[[/folder]]

[[folder: Fridge Horror]]

[[/folder]]

[[folder: Fridge Logic]]

** Testosterone and estrogen are both present simultaneously in a human body, regardless of the gender, just in different amounts which does determines it. Aka, the cell population in a woman would be mostly "feminine" while in a man, it would be mostly "masculine". Nothing strange here.
[[/folder]]

* The Staphylococcus aureus bacterium is depicted as dressed like a queen, with a yellow dress and a gown resembling grape like clusters, which is actually based on their real-life microscopic morphology, and the color of their colonies on culture media.

* While bacteria are presented as evil villains and larger multicellular parasites as kaiju, the viruses are shown as inert "hats" that turn people into zombies...because biologically speaking, viruses aren't actually alive at all, just infectious particles!

* Why does Basophil speaks in a long-winded, poetic way, forcing other cells to interpreted his messages? Because we still aren't sure about what exactly Basophils do.

* In the "Scrape Wound" episode there is mention of the 'outside world' of which there is no return...with cells depicted as tiny humans, what would it be like for them outside the body, with blood coagulating and drying once exposed to air?

* If life in a normal body wasn't terrifyingly enough with its daily threats and bloodthirsty immune-system going at them, imagine the terror the other cells who live in a body that suffer from ''"Autoimmunity"'' instead. Talk about the Inquisition and its witch-hunts reaching a whole new level of personal terror in that case when it occurs in one's own body instead...

** Testosterone and estrogen are both present simultaneously in a human body, regardless of the gender, just in different amounts which does determines it. Aka, the cell population in a woman would be mostly "feminine" while in a man, it would be mostly "male". Nothing strange here.

* In the main series, the Red Blood Cells are coed, but rather than simply {{gender flip}}ing them in ''BLACK'', the squad is all men. There's a good chance that the main series host body actually has AB type blood, with As and Bs treated as separate genders.

* If life in a normal body wasn't terifyingly enough with its daily threats and bloodthirsty immune-system going at them, imagine the terror the other cells who live in a body that suffer from ''"Autoimmunity"'' instead. Talk about the Inquisition and its witch-hunts reaching a whole new level of personal terror in that case when it occurs in one's own body instead...