These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
The Scrappy: The human children that inevitably follow the Cybertronians around are usually the scrappy in their series. This was averted for this show, partly because the kids actually had more interesting personalities, but mostly because they weren't Kicker.
Woolseyism: The dreaded "uh" and "gimme a break!" of Energon is gone, replaced with what constitutes playful romantic banter when both speakers are in their early teens. Homages and an all-new cast turned into known characters a la Transformers: Robots in Disguise, as well.
But mainly, there's the phenomenon that the Transformers Wiki calls "Burning Justice". Galaxy Force was the most "Anime" of the Japan-original Transformers series by far, and the reality-bending powers of wanting something really really hard could make virtually anything happen, with no one treating it as unusual. For Cybertron, this is excised by tying the effects to artifacts that could actually do the things that happened for no reason at all when someone yelled or grunted in the original. It was done so perfectly seamlessly you'd be shocked if you knew the full extent.