These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
The BLAM above involving the skeletons is even more hilarious considering what happens to Marv in Home Alone 2.
Jerkass Woobie: Sure, Neal comes off as a bit of a dick at times especially when he snaps at both the rental agent and the taxi driver, but after all he goes through, including nearly dying at least 3-4 different times, could you really blame him for reaching the breaking point?
Nausea Fuel: Del clearing his sinuses; Del taking off his shoes and socks on the plane; Del leaving wet towels all over the floor. Played for Laughs, of course.
And that... scratching sound their first night in bed together. Whatever it is, eugh!