These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
Game Breaker: The Flash, a secret unlockable gunpod, is quite simply the best weapon in the game. And once you get it, you can select it as a starter gunpod in a new game.
The Grenade and Python also qualify, both arguably the most powerful gunpods in terms of damage per hit. However, the Python is shot out in a rather randomly arranged string, making it hard to hit enemies and thus Awesome, but Impractical.
That One Level: The second half of stage 5, after beating the miniboss. It's so filled with enemies and bullets that if you don't destroy them in time, you'll be swamped all over!