- Crossdressing Voices: Diedrich Bader voices Mrs. Vanders.
- Milestone Celebration: This movie came out in August to coincide with the 45th anniversary of the franchise.
- The Other Darrin: Due to the 45 year gap, the actors for the villains get new actors.
- Mama Mione was voiced by Virginia Gregg in The Scooby-Doo Show, and by Grey DeLisle Griffin in this movie.
- CL Magnus was voiced by John Stephenson on Scooby-Doo, Where Are You!, and by Dee Bradley Baker in this movie.
- Trolling Creator: Jim Krieg, who has written for previous Scooby-Doo shows including Mystery Incorporated, is the writer of this movie. There's a Freeze-Frame Bonus of the Mystery Machine's license plate reading that it is from Crystal Cove... and then the Mystery Machine is destroyed in the next scene.
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