"I just have to take her to the recovery center... She's just...lost consciousness for a little bit..."
The anime version is even more tearjerking with its inclusion of somber music playing in the background.
Satellizer's background. With special mention to her confrontation with her mother after being repeatedly sexually molested by Louis. It's absolutely horrifying that her mother's response is basically a self-centered emotional breakdown and "just put up with it for my sake."
The end of Chapter 65, when Elizabeth, by now revealed to be a genuinely nice person, is released back to her friends after being "punished" for going against the Chevalier (by "punished" read: three straight days of Electric Torture). Not only does she look completelybroken, but when her Limiter, Andre, gets close to her, she's been so badly traumatized that she recoils in fear. She needs a hug badly, and she's too scared to accept one.
Every freaking bit of the E-Pandora/Alaskan facility arc. With special mention to Chapter 81 where Amelia finds out that the entire E-Pandora project was a hoax to buy time for Crazy Scientist Scarlet Oohara's Type Maria clone research. It gets worse when the focus skips to the outside, where you see Genki Girl Rattle buried under about 20 of her friends' corpses.