Tear Jerker / Drake & Josh

  • "Josh is Done". Even sadder after the drama that ensued years later when, in real life, Drake didn't receive an invitation to Josh's wedding, essentially inverting the episode's premise (they patched things up later, however).
    • Drake's breakdown when his life falls apart without Josh leading to an embarrassing incident in the science room.
    Drake: I need you more than you need me! I need you WAY more than you need me! I'm sorry I made you late for your exam! I'm sorry I ran over your bike! I'm sorry I'm probably the worst brother in the world, and you're way better off without me! I just need you to understand...(stammers) Sorry, Josh. I'm sorry. (leaves)
  • Josh's "The Reason You Suck" Speech to Drake in "Dune Buggy" about how Josh Can't Get Away with Nuthin' while Drake gets him into trouble for everything. Like the above scene, it's one of the few moments in the show that's played completely serious.
  • Josh's reaction when he thinks his father is cheating.
  • Drake and Josh's letter from the Christmas Special.
  • Wendy's broken heart after Drake yells at her in "#1 Fan."
  • Megan's broken heart when her boyfriend breaks up with her before her brothers reveal he was cheating on her.
  • Depending on how sympathetic you are to her at this point, Megan being ostracized by her classmates (even being un-invited to a birthday party) because of Josh being her class's student teacher.
http://tvtropes.org/pmwiki/pmwiki.php/TearJerker/DrakeAndJosh