- In the Encanto fic The Runaways Club
it's revealed Isabela watches Grey's Anatomy when she can't sleep.
Films - Live-Action
- In Snatched (2017), Linda's profile on a dating site includes "I love Grey's Anatomy."
- In You Have a Match, Izzy, who wants to be a doctor, plans to use her Instagram to chronicle everything, "like Grey's Anatomy, but make it Gen Z. And with way less murder."
- A sketch from Sesame Street is entitled "A's Anatomy". In this sketch, Doctor Grover attempts surgery on the letter A.
- Family Guy: In "Airport 07", Mayor Adam West reads My Pet Goat to a group of school children. As he reads, he says, "'You know', said my pet goat, 'I'm sure if I watched Grey's Anatomy, I'd like it, but I just don't have the time.'" His reading is then interrupted by an assistant who whispers in his ear to alert him of the plane crash caused by Peter siphoning the fuel in Quagmire's plane. Mayor West ignores the announcement and continues reading, "'You should make the time,' said the farmer.", in a reference to George W. Bush's response to the news of the September 11, 2001 terrorist attacks.
