Homer and Grampa smuggle prescription drugs in from Canada after Mr. Burns announces that the town's new healthcare plan is cutting prescription medications.
This episode contains examples of:
Call Back: This episode mentions Homer's stint as an astronaut.
Even Evil Has Standards: Burns might have selfishly cancelled his employees' health care but he still felt the need to warn a female coworker that her new boyfriend is a married man.
Evil Counterpart: What Ned deems his Canadian counterpart to be after the latter offers him a joint (even though, in Real Life, having non-medicinal marijuana is illegal in Canada. However, unlike most U.S. states and a majority of places overseas, if you get busted on possession of marijuana charges in Canada, you don't get jailtime for it).
Ned: They warned me Satan would be attractive.
Exact Words: At the end of the episode, Burns said he'll restore the plant's health care program to all his "full-time employees". Cut to the next scene with Homer informing Marge he's now a "freelance consultant".
Mistaken for Terrorist: Apu when the guys try go get out of Canada with the drugs. He puts a towel around his head (resembling a turban) and spills hot coffee on his lap, making him let out a scream that sounds like a battle cry.
Mr. Burns' plane is called the "Plywood Pelican", a parody of Howard Hughes' "Spruce Goose" (which was also parodied on the season five episode "$pringfield: or, How I Learned to Stop Worrying and Love Legalized Gambling" during the subplot of Mr. Burns becoming more and more like Howard Hughes in his later years).
The Canadian drugstore Homer and his friends go to is called "Dudley Do-Drugs".
During Ned and Apu's argument over religion, Ned sarcastically quips "Why don't you just call out for Hawkman?" after Apu cries to Shiva for help.