''I against my brothers, my brothers and I against my cousins, my family against the world."
— Bedouin Proverb
Get away from my brother. Before I tear your heart out.
— Damon Salvatore, The Vampire Diaries
Give him back! He's my brother! Take my leg, take my arm, take my heart - anything, you can have it! Just give him back! He's my little brother, he's all I have left!
— Edward Elric, Fullmetal Alchemist
You take care of me. You've always taken care of me. My turn.
— River Tam, Serenity
Be sure to tell Ciel, that if anything happens to my sister I won't forgive him!
— Edward Middleford, Black Butler
John Winchester: All right, if I'm not back Sunday night?
Young Dean: Call Pastor Jim.
John Winchester: Lock the doors and windows, close the shades, and most important...
Young Dean: Watch out for Sammy.
Michael: You said you're a big brother.
Michael: You take care of your little brother? You'd do... anything for him?
Dean: [heartfelt] Yeah, I would.
Michael: My brother's sick.
Dean: The little guy?
Michael: [nodding] Pneumonia. He's in the hospital. It's my fault.
Dean: Ah, c'mon, how?
Michael: I should've made sure the window was latched. He wouldn't have gotten pneumonia if the window was latched.
Dean: Listen to me. I can promise you, that this is not your fault. Okay?
Michael: It's my job to look after him.
" ...if you ever hurt [Vivian], if you ever make her cry... I will find you. And then I will make sure that you find out why the first G in 'Grinning General' might as well stand for 'Gruesome'. Understood?"
Accelerator: I don't understand ya...that fallen lowlife over there and you...why are you covering for a bunch of dolls? They're failed mass production knock offs of you. The one who should feel most annoyed about that in the whole world is you. You dislike seeing something with the same face as you being broken? That's not something to lose your life over. You can't stand the fact that someone else will reach level 6 before you? Or is this atonement for creating the origin of these experiments?
Mikoto: You think that I care about something like "God's Intellect," or that this is something I could atone for? I don't. They are my sisters. It's because these little girls are my sisters. That's all there is to it.
"I just wanted to say a few things to you, Perry. I've never been much of a good example to my brother... Johnny will never look up to me, but when I see you two together he hangs on every word you say as if it's his entire world. If you ever let him down, you'll answer to me."
— Dan Dorian, Scrubs
''"Get away from my brother!"
—Leonardo, Nick TMNT Series
''"You touch my sister again, I'll kill you."
— Sonny Corleone, The Godfather