The very first episode of the series showed the viewers that one of Stu's inventions was a doorbell that had a camera you could speak through. Stu basically invented a prototype version of the Ring Doorbell.
In Season One’s ‘At the Movies’ Godzilla-expy, Reptar, is introduced in a movie where he terrorizes New York City, and 7 years later the real Godzilla would terrorize New York City in the 1998 American Film.
In one episode, Chuckie comments that he was afraid of eating green Jell-O because it could've been alive. A couple of years later, Jell-O's slogan was actually "It's alive!"
In the episode "Garage Sale", Didi gets mortified when the kids stumble upon her and Stu's old disco memorabilia, and when Angelica asks her what "disco" is, she tells her that "It's something that happened a long time ago, and it's never, never coming back!" (which is currently the page quote for Disco Sucks). Years later, the pilot for All Grown Up! would revolve around Stu and Didi competing in a disco dance competition.
In "He Saw, She Saw", Chuckie was hanging out with a girl who had an overprotective brother who, initially, refused to let Chuckie hang out with her. Chuckie later takes on this behavior with Kimi in All Grown Up, freaking out with she starts hanging out with a bad boy and being upset over his best friend (possibly) crushing on his little sister.
In "Unfair Pair", Angelica mentions how Phil and Lil are the only ones among the main characters who have siblings. Later on in the series, Tommy and Chuckie get a brother and a sister respectively, leaving Angelica the only one without any siblings. Additionally the episode "Angelica's Worst Nightmare" has her worrying about the news that she could possibly get a sibling, which is hilarious with the episode where she demands Drew get her a brother or sister.
In "Graham Canyon," Stu and Didi get on route to the Grand Canyon, but, after a wrong turn and a troubling time with the mechanics, they decide to go to the Clam Canyon (a waterpark and seafood restaurant), instead. In the All Grown Up! episode "RV Having Fun Yet?", the Pickles family finally go to the Grand Canyon proper.
The scene where Stu orders 144 eggs, far more than needed for the cake he and Drew were making, becomes this when during the 2018 Olympics, due to a translation error, the chefs for Norway's team accidentally ordered 15,000 eggs when they only needed 1,500. Fans were quick to note the parallels.
"Acorn Nuts and Diapey Butts" has Grandpa Lou say that he doesn't want to turn into a hippie. And a hippie is exactly what he becomes in the revival series.
Similarly in "Angelica's Birthday", he makes a comment about how the best year of his life was being at Woodstock, but then complains about how all those kids made a racket.
A Running Gag was, whenever the babies' scheme or game or whatnot required coffee, they would just use mud ("This coffee tastes like mud!/It IS mud!"). In 2018, Shane Heath released a drink made of powdered mushrooms and herbs marketed specifically as a coffee alternative. Its name? Mud Water.
The premise of the episode "Where's Grandpa?" involves the Pickles family leaving Grandpa Lou at a rest stop when he uses the bathroom. 25 years after the episode aired, a man left behind his wife in the same situation.
In Season 2's "Family Reunion", Tommy saves Angelica from a goat when it attacks her. In "Traditions", the holiday special from the 2021 reboot, Angelica returns the favor.
The voice changer in "Angelica Orders Out" becomes this 3 years later when a beloved slasher franchise used the same concept in a far more devious fashion.
Tim Curry voices the horrible reporter Rex Pester. Curry also voices Nigel Thornberry, and would join the Rugrats in the crossover film Rugrats Go Wild!. What's more is that Rex is indifferent to the children, while Nigel gets left alone with them and cares for them.
Chuckie's ending narration says that things didn't go back to the way they were before because "thanks to baby Dil, they was even better!" The following seasons with Dil in the main cast were seen by many to be the start of the show's Seasonal Rot (though the larger consensus is that it didn't completely jump in quality until after the Even Better Sequel.)
In the Brazilian Portuguese dub, the phone call Kira (voiced by Tânia Gaidarji) has with the groggy Stu (voiced by Élcio Sodré) can now come across as quite amusing, as years later, Gaidarji was cast as Saint Seiya Omega's Gemini Paradox, who notoriously had unreciprocated romantic feelings for Dragon Shiryu, also voiced by Sodré.
Stu's remark about online dating websites being "the future of dating" appears to have aged better than expected, as seen with the rise of dating apps like Tinder.
EuroReptarland was a bit of a Take That! to what was then known as the Euro Disney Resort (a foreign theme park based on popular children's characters that was out of touch with Parisian culture). Compare that with the turnaround that the real Disneyland Paris has experienced since the film came out, which has become one of the most popular destinations in Paris due to bringing more Parisian culture into the park.
