The ending of his Mario is Missing / Mario's Time Machine Review. There's just something heartwarming about seeing the IG, Ronnie and Luigi enjoying their vacation.
The season 4 finale where everyone shares a standing ovation after IG and co. saved the city from the giant HAL Robot. Granted the citizens mistake the protagonists for the Power Rangers but it's still a go happy, go lucky kind of way to end the fourth season.
Meta Example: Chris Bores telling his backstory and he opens up on AVGN. This is also probably one of the honest videos he's ever done.
He also states that James Rolfe was really an inspiration for him.
He also says that he's sorry if he ever insulted anyone in the past.