- David asks Rose to suck dick. Rose asks David to suck dick. David asks Kenny to suck dick.
- The messed up game of pictionary.
- "Black Cock Down!!!"
- Edie hitting on Rose and later her confessing it to Melissa.
- Kenny practicing kissing with Rose and Casey.
- Melissa's reaction to said practice kiss.
- The homage to Flashdance.
- Kenny getting bit in the groin by a spider and everyone's reactions to it.
- David describing the type of haircut he wants.
- The guy in the background can be seen watching the entire thing, and he points to his head and says "right here." "Yeah give me that."
- On the plane David introduces his "kids" to the flight attendant Casey mischievously ad-libs:
Yeah. I'm going through all those typical teenage girl issues, like finals and college applications and am I gonna get asked to prom? Plus, I haven't gotten my period in, like, two months, which is really weird, because I've mostly just been doing anal...(Kenny who is sitting next to her and drinking a bottle of water does a Spit Take)
- The group narrowly avoiding getting caught at the border when a group of Mexicans crawl out from under the RV and make a run for it.
- The blooper that has Jason Sudeikis, Emma Roberts, and Will Poulter play the Friends theme as a joke for Jennifer Aniston.
- "Fuck off, real-life Flanders!"
- Kenny singing/rapping TLC's "Waterfalls".
- Any time one of them instinctively starts acting like their role in private, and they all roll with it without calling each other out.
- "You can buy a house! And then run away from it!"
- Rose: "It also sends that message to teens, just stick to the big A". David: "Yeah, Anal".
- In one of the Hilarious Outtakes at the end, Emma Roberts has a little trouble opening the mini-fridge in the RV:
Emma: It takes two men to open this mini-fridge.
Emma: (laughing) It's slippery.