The same item appears in the Super Smash Bros. series starting from Brawl, with much the same effect. Humorously, the curry even affects ROB (who is a robot and has no visible orifice), Mega Man (who, while possessing a mouth, is still a robot), and Falco (being a bird, he should be immune to spice).
Kingdom of Loathing has ability Chronic Indigestion gained from eating an ultra-spicy burrito made with enchanted beans. It does 10-15 HOT damage + however full you are.
Blast Seeds cause you to exhale an explosion when you eat them in Pokémon Mystery Dungeon. Anyone caught in the blast takes damage.
One of the mini-games in Rayman: Raving Rabbids 2 has the titular Rabbids using this as a means to cook chicken.
There's a craftable food in World of Warcraft called Dragonbreath Chili. Eating it will cause the player to occasionally breathe fire that does minor damage to nearby enemies. During the Midsummer Fire Festival, some vendors sell a drink that causes the player to breathe fire, although unlike the chili it doesn't harm enemies.
The Pandaren Brewmaster hero in Warcraft III also sports a flame breath attack where in he swigs alcohol from a giant keg and then spews the ignited mixture all over his enemies. If one casts "Drunken Haze" (more or less hurling booze on the enemy and rendering them instantly drunk!) they'll also ignite and take additional damage over several seconds as they burn! The Mists Of Pandaria expansion of World of Warcraft keeps this ability for monks who choose the Brewmaster talent tree.
Mr. Luggs in Luigi's Mansion apparently eats something hot enough to cause this effect, shooting fifteen fireballs at Luigi at a time before getting tired and able to be attacked.
In Dragon Quest VIII, it is possible to feed Munchie, your mouse, a very spicy cheese to make it breath fire. However, this isn't only its ability. Feed it a variety of cheese and it will spew out things accordingly (including, but not limited to, frozen cheese, steel cheese for buffing, and even angel cheese to revive allies).
In the Nancy Drew game Legend of the Crystal Skull, feeding Bess Marvin several servings of hot-sauce-drenched Cajun cooking will cause the screen to turn reddish as she belches a puff of flame.
In Delicious 7: Emily's True Love this happens to a restaurant critic after a waitress slathers his food with hot sauce to get back at the restaurant owner for proposing to her and then dating Emily.
In Speedy Gonzales: Los Gatos Bandidos, Speedy can obtain a flame attack if he drinks hot sauce. This is necessary in the Ancient Keep in order to light the firewood so the cauldron can emit clouds of smoke he can ride on like platforms.
In The Sims 4, this is what happens to sims who fail the spice challenge at the San Myshuno Spice Festival.