Whispy from Asperchu talks entirely in Blind Idiot Translated Spanish. Possibly deliberate, as Whispy is described as "slow in the minds" when he is first introduced.
In one Ghastly's Ghastly Comic strip Japanese company Goodbye Pussy discovered that they English translation "was not adequately elegant" and thus their product was released with "Warranty assurance three years. Not for children" translated into "Not recommended for 3 years and under". The kicker is that the product was a BIG dildo. Hey, it's Ghastly's, after all.
Done in-universe in Sinfest when sexy Monique finds a Scandinavian fansite dedicated to her and lets a website translate: "'Nique has owning for universal buttocks. Her today please to scandal buckets of infinite pony. Real jubilate to freshness!"
Juan Valdés in Captain SNES: The Game Masta speaks in computer-translated Spanish, as the author outright admits he doesn't know Spanish. That works for short comments, but any decent sentence sounds awkward.