In Pac-Man: Championship Edition DX, eating a line of ghosts is so satisfying that it was mentioned in most of the reviews in this game.
In all incarnations: that magical moment when you manage to eat a power pellet just as you've been cornered by ghosts on both sides, and proceed to eat them both. Alternately, when you manage to time it so that you eat a power pellet as a ghost is coming right at you, plowing right into it before it has a chance to turn and run.
In one episode of the cartoon, Mezmaron tells the ghost monsters to steal an armored truck and its cargo. They eventually triumph in spite of being reduced to pairs of eyes. That moment of awesomeness isn't diminished by the fact it was a Meaningless Villain Victory.