Deadpool may be emoting the three Freudian archetypes of the mind; Superego, Ego and Id. His white caption box is the most sensible one, and thus the Superego. The more out of touch yellow caption box is Ego, a less sensible one. His chaotic, random persona word balloons and occasional change to his POV are the Id, the no before or after thought.
Or maybe, as Uncanny X-Force writer Rick Remender suggests, is Wade a Sad Clown who just wants to be loved?
This theory is backed up by one story where Deadpool decides to kill off his entire fanbase so his comic can end and he can just die.
Doctor Strange: During his time as a surgeon Stephen Strange is always shown as the biggest, most selfish jerk possible. But Brian K. Vaughan's Doctor Strange: The Oath miniseries implied that maybe he was this way because he couldn't cope with his inability to save everybody, and instead of getting emotionally invested, he had chosen to distance himself from his patients, becoming a greedy, uncaring jerk in the process.
As it was pointed out during his initial adventures Strange might have been the most rational of all Marvel superheroes, lacking the irresponsibility constantly shown by Reed Richards and Bruce Banner during those days and not sending kids to fight his war, like Charles Xavier.
Is Reed Richards really such an arrogant, aloof guy? Or is he so superintelligent that he can't relate to other people? Or is he overcompensating for the guilt he still feels over getting his family transformed into freaks? Or, as suggested by Grant Morrison, does he have Asperger's syndrome?
Galacta: Daughter of Galactus: In-Universe, Gali views her "daddy" Galactus as a callous, world-eating monster. She desperately wishes to remove herself from her father's shadow and overcome her base urges to consume everything in her path, though the Tapeworm Cosmic makes this very challenging. However, Galactus's surprise appearance at the end of the comic seems to favourably change her opinion of him, as he informs her that the "Tapeworm Cosmic" is actually a foetal form of another nascent cosmic entity developing inside her; in other words, she's pregnant. She considers the possibility that Galactus does have some fatherly compassion after all.
Moon Knight: Obsessive Abraham Van Helsing style werewolf hunter, costumed vigilante, Batman parody, agent of a spirit of vengeance, super hero, mercenary looking for redemption, just a puppet of Khonshu, and schizophrenic sadist are just some of his many possible variants, all of whom are canon portrayals. His alters are subject to this too: Steven Grant is either reasonable, intelligent and sophisticated or a shallow billionaire playboy, while Jake Lockley is either a gruff but sociable Nice Guy who keeps Moon Knight grounded or easily the most brutal, violent and terrifying of his personalities.
The Punisher: Many comics portray the Punisher as being just a jaded, cynical man who wants to make absolutely, positively sure that the criminals he stops aren't going to wind up in a Cardboard Prison to break out again and commit crimes like the one that killed his family. Some other interpretations paint him closer to a Serial Killer who's using criminals as an acceptable target to vent his bloodlust; these see his actions as more like bloody murder than vigilantism. The second interpretation greatly pleases some fans and infuriates others to no end.
He could be both. It's been over 30 years (which is about 7 years in Comic-Book Time) since his family was killed. He might have been just cynical back then; but after so long, he's bound to be a little crazy.
The Punisher presents a special problem: The arguments for his being in the moral right (killing some people to save many) require him to live in a world where his logic is true. Unfortunately, he lives in a world where other ways of solving things constantly show up. Naturally, he seems a little crazy.
Case in point - he's portrayed as a lunatic more commonly when he's co-starring with other heroes like Daredevil. In his own book, he's shown in a more positive light.
His more extreme stories in The Punisher MAX are not canonical with the main Marvel Universe.
Even writers started to pick sides in this one - Greg Rucka has repeatedly stated that he dislikes the interpretation of Frank as crazy.
Spider-Man: Is Spider-Man a battle-hardened self-taught warrior using a combination of wit, intelligence, strength, and bitter experience to become a dangerous foe? Or young, inexperienced, naive newbie who can't keep his mouth shut? Even the writers aren't sure.
Granted, these ideas are not exclusive nor do they contradict each other. In fact, it would make the most sense for him to start as the latter and become the former over time.
In his review of One More Day, Linkara paints a chilling picture of Spidey as an irresponsible hypocrite who suffers from a severe case of Aesop Amnesia, hurts his friends and loved ones under the guise of "something more important came up as Spider-Man" and making excuses for himself, never taking the time to make any long term plans in life (he has no life insurance for starters) and never made any plans to help his family if the very real possibility of him getting killed in action were to occur. (In fairness, Linkara does bring up that a huge part of the problem stems from how the writers and Marvel editorial seem to adamantly refuse to let Peter Parker grow up and act his age, and part of his rant is his own personal jaded perspective.)
This /co/post◊ has suggested the idea of J. Jonah Jameson as a Secret Secret-Keeper who is tough on Spider-Man in order to motivate him to keep working harder in defending the city. Other interpretations:
Jameson is a huckster, and the Bugle is a borderline-tabloid, which he uses for his anti-Spidey crusade regardless of facts.
Or even the reverse: Jameson is a huckster, and the Bugle is a borderline-tabloid, but his feud with Spider-Man is greatly exaggerated just to sell a lot of papers.
Jameson is the Butt-Monkey, just there for comic relief.
Jameson is a good, honest newspaperman, and the Bugle is a good paper, he just happens to have a bug up his butt about Spidey.
Jameson is a psychopath who has commissioned the creation of lethal anti-Spidey robots, and he should be in jail.
Jameson is a rugged idealist who believes that Spider-Man has a duty to protect the people of New York, and he runs his anti-Spidey crusade to ensure that he'll never be able to selfishly use his powers for wealth or fame.
The Ultimates: Is Red Skull lying about wanting a better life? Is he just trying to screw with Fury? Is he deluding himself? Is he just trying to justify his actions?
Is Cyclops just a wuss who's occupying space until Wolverine can save the day, or is he the Marvel Comics equivalent of Batman with Eye Beams? Is his behavior since Joss Whedon's run a case of finally getting rid of Badass Decay and living up the the reputation of leader he was supposed to be or did he simply take a level in jerkass? In a post AVX Marvel world, is he a tarnished hero seeking redemption, or just a big damn bigot who doesn't care who he hurts anymore?
When Colossus took the lethal Legacy Virus antidote that would kill its host body while releasing a cure into the atmosphere, thus curing anyone with the Legacy virus anywhere in the world, was it a Heroic Sacrifice to save the world? Or, given that he had lost his family and seen his former girlfriend move on with her life, was it a suicide gussied up to look noble? After Colossus became the new Juggernaut, a new alternate interpretation surfaced - that he has a self-destructive messiah complex that forces him to always bear all the pain and suffering there is to bear.
during his initial adventures Strange might have been the most rational of all Marvel superheroes, lacking the irresponsibility constantly shown by Reed Richards and Bruce Banner during those days and not sending kids to fight his war, like Charles Xavier.
