When you find yourself trying to remember a show (or any works) that's on the tip of your tongue but just out of reach, come here - the collective brain of the TVTropes community can probably help. Post all the details you can remember (examples help). If you're looking for a trope, head over to Trope Finder. Have general questions about tropes? Visit Ask The Tropers!
By Nickalo do you mean Nickelodeon?
Was the skin glove to bypass a fingerprint scanner or to leave fingerprints at a crime?
Can you describe the villain and who "her" is (role in the show, gender, looks etc)?
Working on cleaning up List Of Shows That Need Summary
If the villain just took her prints from a glass instead of flaying her hand, it could be Mission: Top Secret.
There was also the reverse, where in an episode of Ocean Girl, a government agent drinks with the villain and steals his glass to check his prints; after he departs, the villains peels the "skin" of his own hand, revealing it was a fake with someone else's fingerprints.
"And as long as a sack of shit is not a good thing to be, chivalry will never die."
Show on Nick, British or Australian accent. One villain took skin ok hand and used it as a glove to impersonate her.