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1->''Curiously enough, the only thing that went through the mind of the bowl of petunias as it fell was "Oh no, not again". Many people have speculated that if we knew exactly why the bowl of petunias had thought that we would know a lot more about the nature of the universe than we do now.''
2-->-- ''Literature/TheHitchhikersGuideToTheGalaxy1''
3
4->''I just got a new one...''
5-->-- '''[[MadeOfIron Taylor]]''', [[spoiler:after getting her arm crushed less than three days after having her arm (and much of her lower body) cut off,]] ''Literature/{{Worm}}''
6
7->'''Tagon:''' I can't think of a worse way to wake up than discovering [[BrainInAJar my head is in a jar.]]\
8'''Der Trihs:''' Try waking up with your head in a jar ''and'' having deja-vu.
9-->-- ''Webcomic/SchlockMercenary''
10
11->''"Wait... Seriously? Why are you here, Callie? WE ALREADY RESCUED YOU."''
12-->-- '''Marie''', ''VideoGame/Splatoon2''
13
14->A few Sons of Ether speculate that the [[HumongousMecha War Machine]] escaped a catastrophic [[MagicMisfire Paradox backlash]] because [[UsefulNotes/WorldWarI The Great War]]'s influx of techno-monstrosities - mustard gas, machine guns, tanks, warplanes, flame-throwers, mortar, you know, all the stuff that makes such pretty piles of human remains - had [[SeenItAll numbed the soldiers' sense of disbelief]]. By the time Dr Reinhardt's contraption appeared, they just shrugged their collective shoulders. "Oh no," they probably said, "not ''another'' one!"
15-->--''TabletopGame/MageTheAscension - The Technomancer's Toolbox''
16
17->Not again... I have feelings too, you know. I'm getting a bit sick of this. I'm not [[RidiculouslyHumanRobots some hunk of metal]] to be drooled over! And no means no!
18-->--'''Mr Pendulum,''' being approached by yet another horny Leprechaun, ''ComicBook/WormwoodGentlemanCorpse: It Only Hurts When I Pee''
19
20->'''Bumblebee:''' And who [[AnIcePerson uses ice as a weapon?]] [[YouFightLikeACow What are you, a refrigerator?]]\
21'''Blitzwing:''' You want heat?! I'll give you more than you can handle!\
22''(Blizwing transforms from jet mode to tank mode... [[DidntThinkThisThrough while still several hundred feet in the air]].)''\
23'''Blitzwing:''' Oh slag! Not again! ''(crashes)''
24-->--''WesternAnimation/TransformersAnimated'', Megatron Rising: Part 2
25
26->'''Little John:''' Now, what about that for luck? It's only a circus, a peanut operation.
27->'''Robin Hood:''' Peanuts? Why, you dunce, that's the royal coach! It's Prince John himself!
28->'''Little John:''' ''The Prince?!'' Wait a minute, there's a law against robbin' royalty. I'll catch you later!
29->'''Robin Hood:''' What? And miss this chance to perform before royalty?
30->'''Little John:''' ''(sigh)'' Here we go again.
31-->--''WesternAnimation/RobinHood1973''
32
33->'''Squidward:''' We gotta call a hospital!
34->'''Mr. Krabs:''' Won't do any good. I've seen this before. When that pie goes up to bat--I mean, hits his lower intestine... ''BOOM!''
35->'''Squidward:''' ''You've seen this before?!''
36->'''Mr. Krabs:''' Eleven times, as a matter of fact.
37->'''Squidward:''' ''(rushes to the phone and dials)'' Yes, hello?! Doctor?! Hospital?! ...Won't do any good? ...''Eleven times?!'' ''(hangs up)'' Oh! He's a goner...
38-->--''WesternAnimation/SpongeBobSquarePants'', "[[Recap/SpongeBobSquarePantsS2E4DyingForPieImitationKrabs Dying for Pie]]"
39
40->"I wonder how ComicBook/CaptainAmerica's gonna take it when he finds out the case that almost finished him just reopened itself."
41-->-- '''ComicBook/NickFury''', ''ComicBook/TheUltimates''
42
43->''Aw, shit. Here we go again.''
44-->-- '''CJ''', ''VideoGame/GrandTheftAutoSanAndreas''
45
46-> ''Oh no! Oh come on! No! Not again! [[GameBreakingBug THIS ONE'S BROKEN TOO!]]''
47-->-- '''Kirito''', ''WebVideo/SwordArtOnlineAbridged''
48
49->'''Pastor Drom:''' As long as I keep licking these horrible inedible fruits, I'll be safe from the mind control. [[ARareSentence Wow, there's a phrase I didn't expect to have to utter twice in one lifetime.]]\
50'''Reverend Mord:''' I beg your pardon?\
51'''Pastor Drom:''' College was wild.
52-->--''Podcast/TheHiddenAlmanac''
53
54->'''Ember:''' [[JustBeforeTheEnd The end is almost here, Eliot]].
55->'''Eliot:''' The end of what?
56->'''Ember:''' Of everything. Of this land. This world. Fillory is dying.
57->'''Eliot:''' What? Oh come on! What are you talking about?
58->'''Pegasus:''' Oh no. [''sighs''] Not again.
59-->--''[[Literature/TheMagicians The Magician's Land]]''
60
61->"Oi, what do you mean, 'oh, again' -- is this a ''regular occurence''??"
62-->--'''Rin''', ''Webcomic/CatGoesMeow'', "[[https://accelldraws.tumblr.com/post/702922629246566400/a-temporary-wrench-in-the-pubby-tail-wag Wag Machine Broke]]"
63
64->''"AAARRGH! Not ''again''!"''
65-->-- '''N. Gin''', ''VideoGame/CrashBandicoot3Warped''
66
67->'''Angry Dad''': (''at his power plant workstation'') This job sure is easy. [[TemptingFate Now to press this]] [[BigRedButton button!]]
68->(''The cooling towers outside [[EverythingMakesAMushroom explode in a giant mushroom cloud]]'')
69->'''Angry Dad''': '''NOT ''AGAAAAAAIN!'''''
70->'''Angry Dad's Boss''': Angry Dad, you're fired!
71->(''[[YourHeadASplode Angry Dad's head explodes]] in a smaller mushroom cloud'')
72-->-- ''WesternAnimation/TheSimpsons'', "[[Recap/TheSimpsonsS13E18IAmFuriousYellow I Am Furious (Yellow)]]"
73
74->''"No...NOT YOU AGAIN!"''
75-->-- '''[[ButtMonkey The Boat Captain]]''', ''VideoGame/GodOfWarII'', upon being resurrected as undead and having to face Kratos again during the Barbarian King fight.
76
77->'''Woody:''' Wait, where's Buzz?\
78'''Rex:''' Lotso did something to him!\
79'''Slinky Dog:''' He thinks he's a real Space Ranger again!\
80'''Woody:''' Oh ''no''...\
81'''Hamm:''' Oh, yes. Return of the astro-nut!
82-->-- ''WesternAnimation/ToyStory3''
83

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