History TearJerker / MassEffectTheEquestrianEquation

* In ''Shades of Twilight'', the schism between Twilight and Applejack over the latter's abduction of Dr. Hern from the hospital. Applejack accuses Twilight of betraying her when Twilight insists on informing Lt. Pyres of the situation, and though she tries to apologize after both Twilight and Pyres do everything they can to protect both her and Patricia, she's burned so many bridges with her behavior that Twilight just gives her the cold shoulder.

** [[spoiler:Even if WordOfGod confirms that the kidnapped ponies will be OK, it's still a bad ending to the chapter]].

* New Ponyville is attacked by a series of firebomb detonations, and eight ponies (including Scootaloo) are abducted while the ensuing chaos has everyone distracted. When Rainbow Dash goes after the abductors, she is subjected to a brutal CurbStompBattle by an Asari Commando which ends with her getting shot in both wings. The only friendly close to her is a changeling drone that can either be ordered to [[SadisticChoice follow the abductor's ion trail, potentially leaving Rainbow Dash's wings crippled if her wounds are left untreated, or try to get her immediate treatment knowing that there's no one else in a position to follow the trail before it goes cold.]]

* New Ponyville is attacked by a series of firebomb detonations, and nine ponies (including Scootaloo) are abducted while the ensuing chaos has everyone distracted. When Rainbow Dash goes after the abductors, she is subjected to a brutal CurbStompBattle by an Asari Commando which ends with her getting shot in both wings. The only friendly close to her is a changeling drone that can either be ordered to [[SadisticChoice follow the abductor's ion trail, potentially leaving Rainbow Dash's wings crippled if her wounds are left untreated, or try to get her immediate treatment knowing that there's no one else in a position to follow the trail before it goes cold.]]

** Which according to the Equestrian Codex, like the UsefulNotes/{{Amish}}, is considered one of the worst punishment one can face within the Herd, imprisonment being just adding salt to the wound.

* In ''Shades of Twilight'', the schism between Twilight and Applejack over the latter's abduction of Dr. Hern from the hospital. Applejack accuses Twilight of betraying her when Twilight insists on informing Lt. Pyres of the situation, and though she tries to apologize after both Twilight and Pyres do everything they can to protect both her and Patricia, she's burned so many bridges with her behavior that Twilight just gives her the cold shoulder.

* The schism between Twilight and Applejack over the latter's abduction of Dr. Hern from the hospital. Applejack accuses Twilight of betraying her when Twilight insists on informing Lt. Pyres of the situation, and though she tries to apologize after both Twilight and Pyres do everything they can to protect both her and Patricia, she's burned so many bridges with her behavior that Twilight just gives her the cold shoulder.
* Just the fact that the Equestrians were ripped out of a happy, peaceful life and were suddenly thrust into the frequently harsh and demanding galaxy of ''Franchise/MassEffect'' with little more than enough general information to get by suddenly jammed into their heads. Not to mention suddenly waking up and finding that some of the friends, family and neighbors that you grew up with your entire life were nothing more than programs.

* Just the fact that the Equestrians were ripped out of a happy, peaceful life and were suddenly thrust into the frequently harsh and demanding galaxy of VideoGame/MassEffect with little more than enough general information to get by suddenly jammed into their heads. Not to mention suddenly waking up and finding that some of the friends, family and neighbors that you grew up with your entire life were nothing more than programs.

* Twilight and Celestia share a tearful goodbye in the Harmony Core chamber, moments before the Awaken Protocol is to be launched. When Twilight is momentarily distracted by the control console, the Princess turns, walking away as her hologram projection fades to nothing. Her last words are: "Goodbye, my little pony."

* Just the fact that the Equestrians were ripped out of a happy, peaceful life and were suddenly thrust into the frequently harsh and demanding galaxy of VideoGame/MassEffect with little more than enough general information to get by suddenly jammed into their heads. Not to mention suddenly waking up and finding that some of the friends, family and neighbors that you grew up with your entire life were nothing more than programs.
* Twilight, upon realizing that her world is a simulation and that she can't trust anything she knows to be real, has an emotional breakdown and needs to literally hold onto Shepard for support.

* Just the fact that the Equestrians were ripped out of a happy, peaceful life and were suddenly thrust into the frequently harsh and demanding galaxy of VideoGame/MassEffect with little more than enough general information to get by suddenly jammed into their heads. Not to mention suddenly waking up and finding that some of the friends, family and neighbors that you grew up with your entire life were nothing more than programs.

* Just the fact that the Equestrians were ripped out of a happy, peaceful life and were suddenly thrust into the frequently harsh and demanding galaxy of VideoGame/Mass Effect with little more than enough general information to get by suddenly jammed into their heads. Not to mention suddenly waking up and finding that some of the friends, family and neighbors that you grew up with your entire life were nothing more than programs.