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* Everyone in the [[Franchise/MarvelUniverse Weapon Plus]] programme(s) except ComicBook/{{Wolverine}} and ComicBook/CaptainAmerica qualifies. The rest were supervillains and each was the first, and often only, in their generation of the program. Some of them, especially among Wolverine's fellow Weapon X products, would eventually make a HeelFaceTurn, but [[SelfDemonstrating/{{Deadpool}} that didn't necessarily involve becoming any less psycho]].

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* Everyone in the [[Franchise/MarvelUniverse Weapon Plus]] programme(s) except ComicBook/{{Wolverine}} and ComicBook/CaptainAmerica qualifies. The rest were supervillains and each was the first, and often only, in their generation of the program. Some of them, especially among Wolverine's fellow Weapon X products, would eventually make a HeelFaceTurn, but [[SelfDemonstrating/{{Deadpool}} [[ComicBook/{{Deadpool}} that didn't necessarily involve becoming any less psycho]].
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This tends to happen ''very'' frequently to projects started by altogether good conspiracies who want to [[MassSuperEmpoweringEvent create an army of heroes]]. By the time they get around to perfecting the process and the hero undergoes it, "big brother" will show up and either [[CirclingMonologue "offer"]] to form a SecretProjectRefugeeFamily after killing their "parents"... or kill him dead if he refuses. [[HerosEvilPredecessor Inevitably, any previous version of a hero who reappears is invariably evil.]]

Expect this monster to be named some variation of Alpha, Proto, or [[MyHeroZero Zero.]]

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This tends to happen ''very'' frequently to projects started by altogether good conspiracies who want to [[MassSuperEmpoweringEvent create an army of heroes]]. By the time they get around to perfecting the process and the hero undergoes it, "big brother" will show up and either [[CirclingMonologue "offer"]] "[[CirclingMonologue offer]]" to form a SecretProjectRefugeeFamily after killing their "parents"... or kill him dead if he refuses. Inevitably, [[HerosEvilPredecessor Inevitably, any previous version of a hero who reappears is invariably evil.]]

evil]].

Expect this monster to be named some variation of Alpha, Proto, or [[MyHeroZero Zero.]]
Zero]].
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Maybe [[Film/{{Ghostbusters 1984}} the streams crossed]], the SuperSerum is actually of the [[PsychoSerum Psycho]] or [[ToxicPhlebotinum Toxic]] flavors, the janitor [[BullyingADragon tossed rotten tomatoes at it]], the psych evaluations weren't [[CriticalPsychoanalysisFailure as rigorous]] as they should have been, or an honest to goodness [[DidntSeeThatComing unforeseen complication]] happened during Alpha Testing (if there was any, that is). Whatever the case, the experiment has GoneHorriblyWrong and the first and eldest of a nascent [[TheChosenMany Chosen Many]] has gone rogue [[PhlebotinumRebel (and not in the good way)]], is evil, and likely wants to kill its makers ''and'' younger siblings.

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Maybe [[Film/{{Ghostbusters 1984}} the streams crossed]], the SuperSerum is actually of the [[PsychoSerum Psycho]] or [[ToxicPhlebotinum Toxic]] flavors, the janitor [[BullyingADragon tossed rotten tomatoes at it]], the psych evaluations weren't [[CriticalPsychoanalysisFailure as rigorous]] as they should have been, or an honest to goodness [[DidntSeeThatComing unforeseen complication]] happened during Alpha Testing (if there was any, that is). Whatever the case, the experiment has GoneHorriblyWrong and the first and eldest of a nascent [[TheChosenMany Chosen Many]] has gone rogue [[PhlebotinumRebel (and ([[PhlebotinumRebel and not in the good way)]], way]]), is evil, and likely wants to kill its makers ''and'' younger siblings.

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[[folder: {{Anime}} and {{Manga}}]]

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[[folder: {{Anime}} [[folder:{{Anime}} and {{Manga}}]]



* Everyone in the [[Franchise/MarvelUniverse Weapon Plus]] programme(s) except ComicBook/{{Wolverine}} and ComicBook/CaptainAmerica qualifies. The rest were super-villains and each was the first, and often only, in their generation of the programme. Some of them, especially among Wolverine's fellow Weapon X products, would eventually make a HeelFaceTurn, but [[SelfDemonstrating/{{Deadpool}} that didn't necessarily involve becoming any less psycho]].
* Valentine Romanov, eldest brother of ''ComicBook/NikolaiDante'', was the first Romanov to be bonded with a weapons crest. Unfortunately, his was a prototype which caused [[BodyHorror massive scarring, making him resemble a metallic skeleton]] along with some ''major'' SanitySlippage.

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* Everyone in the [[Franchise/MarvelUniverse Weapon Plus]] programme(s) except ComicBook/{{Wolverine}} and ComicBook/CaptainAmerica qualifies. The rest were super-villains supervillains and each was the first, and often only, in their generation of the programme.program. Some of them, especially among Wolverine's fellow Weapon X products, would eventually make a HeelFaceTurn, but [[SelfDemonstrating/{{Deadpool}} that didn't necessarily involve becoming any less psycho]].
* Valentine Romanov, eldest brother of ''ComicBook/NikolaiDante'', was the first Romanov to be bonded with a weapons crest. Unfortunately, his was a prototype which that caused [[BodyHorror massive scarring, making him resemble a metallic skeleton]] along with some ''major'' SanitySlippage.
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* ''WesternAnimation/{{Robotboy}}'' had Protoboy, Robotboy's older brother who was captured and turned into an OmnicidalManiac by Dr. Kamikazi. He would go to various lengths to attempt to prove himself as Professor Moshimo's best invention/kill him, including [[GrandTheftMe switching his CPU with his brother's]] so he could get close to Moshimo and later threatening to kill Moshimo in a robot factory by pouring molten titanium on him unless Robotgirl offers to take his place. While he had a penchant for coming back to life after being blown up, he's supposedly KilledOffForReal in the aforementioned factory.

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* ''WesternAnimation/{{Robotboy}}'' had Protoboy, Robotboy's older brother who was captured and turned into an OmnicidalManiac by Dr. Kamikazi. He would go to various lengths to attempt to prove himself as Professor Moshimo's best invention/kill him, including [[GrandTheftMe switching his CPU with his brother's]] so he could get close to Moshimo and later threatening to kill Moshimo in a robot factory by pouring molten titanium on him unless Robotgirl offers to take his place. While he had a penchant for coming back to life after being blown up, he's supposedly KilledOffForReal repeatedly killed, his final appearance in the aforementioned factory.factory has his fate an UncertainDoom.
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* In ''VideoGame/BioShock2'', the Alpha Series was the first line of Big Daddies who, due to their bond with an individual Little Sister, would go either comatose or insane if their Little Sister was killed or saved by Tenenbaum.

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* In ''VideoGame/BioShock2'', the Alpha Series was the first line of Big Daddies who, due to their bond with an individual Little Sister, would go either comatose or violently insane if their Little Sister was killed or saved by Tenenbaum.
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* According to Jewish folklore, UsefulNotes/{{Lilith}} is a PsychoPrototype of Eve. After [[StrawFeminist refusing to obey]] Adam and {{God}}, Lilith was expelled from Eden and became the demonic MotherOfAThousandYoung. God then created Eve to replace her.

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* According to Jewish folklore, UsefulNotes/{{Lilith}} Myth/{{Lilith}} is a PsychoPrototype of Eve. After [[StrawFeminist refusing to obey]] Adam and {{God}}, Lilith was expelled from Eden and became the demonic MotherOfAThousandYoung. God then created Eve to replace her.
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* ''WesternAnimation/{{Robotboy}}'' had Protoboy, Robotboy's older brother who was captured and turned into an OmnicidalManiac by Dr. Kamikazi. He would go to various lengths to attempt to prove himself as Professor Moshimo's best invention/kill him, including [[GrandTheftMe switching his motherboard with his brother's]] so he could get close to Moshimo and later threatening to kill Moshimo in a robot factory by pouring molten titanium on him unless Robotgirl offers to take his place. While he had a penchant for coming back to life after being blown up, he's supposedly KilledOffForReal in the aforementioned factory.

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* ''WesternAnimation/{{Robotboy}}'' had Protoboy, Robotboy's older brother who was captured and turned into an OmnicidalManiac by Dr. Kamikazi. He would go to various lengths to attempt to prove himself as Professor Moshimo's best invention/kill him, including [[GrandTheftMe switching his motherboard CPU with his brother's]] so he could get close to Moshimo and later threatening to kill Moshimo in a robot factory by pouring molten titanium on him unless Robotgirl offers to take his place. While he had a penchant for coming back to life after being blown up, he's supposedly KilledOffForReal in the aforementioned factory.

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* While Ash the android didn't technically go insane in ''Film/{{Alien}}'', it did engage in homicidal behavior, unlike the more "stable" later version represented by Bishop in ''Film/{{Aliens}}''. Also, Ash "malfunctioning" is merely the official explanation to cover up that [[spoiler: he was fulfilling his mission to get the Xenomorph back to Earth without the interference of the crew]].

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* *''Franchise/{{Alien}}''
**
While Ash the android didn't technically go insane in ''Film/{{Alien}}'', it did engage he engaged in homicidal behavior, unlike the more "stable" later version represented by Bishop in ''Film/{{Aliens}}''. Also, Ash "malfunctioning" is merely the official explanation to cover up that [[spoiler: he was fulfilling his mission to get the Xenomorph back to Earth without the interference of the crew]].crew]].
**''Film/AlienCovenant'' marks the debut of the Neomorphs and Prateomorphs, ancestors [[spoiler:(or knockoffs, according to the novelisation)]] of the classic Xenomorphs David created using Chemical A0-3959x.91 – 15. Both creatures are animalistic killing machines with hyper-aggressive temperaments that rival or even surpass those of their descendants[[spoiler:/inspirations]].
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** In the backstory to ''VideoGame/MegaManX'', Dr. Light feared that the eponymous X, the first robot with true free will, could become this, which is why he sealed him away for 30 years to test his morality.

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** In the backstory to ''VideoGame/MegaManX'', Dr. Light feared that the eponymous X, the first robot with true free will, could become this, which is why he sealed him away for 30 years to test his morality. [[spoiler:Given what happens to [[KnightTemplar Copy X]] in ''VideoGame/MegaManZero'', who is effectively X ''without'' said testing or even much life experience in general, he was likely right to be concerned.]]
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* In the ''VideoGame/CrashBandicoot'' series, recurring villain [[KangaroosRepresentAustralia Ripper Roo]] is [[BigBad Dr. Cortex's]] very first [[UpliftedAnimal mutant animal soldier]]. Crash himself was a later attempt... and while ''he's'' a bit [[TheFool daft]], Roo is so [[AxCrazy nuts]] that he's always in a straitjacket ([[HandyFeet which, honestly, doesn't slow him down]]).

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* In the ''VideoGame/CrashBandicoot'' series, recurring villain [[KangaroosRepresentAustralia Ripper Roo]] is said to be [[BigBad Dr. Cortex's]] very first [[UpliftedAnimal mutant animal soldier]]. The brainwashing procedure drove Roo so nuts that he became a cackling madman in a straitjacket. Crash Bandicoot himself was a later attempt... and while ''he's'' a bit more successful attempt--although he's plenty [[TheFool daft]], Roo is so [[AxCrazy nuts]] that he's always daft]] in a straitjacket ([[HandyFeet which, honestly, doesn't slow him down]]).his own right.
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* ''VideoGame/MassEffectAndromeda:'' The Kett Behemoth, [[spoiler:formerly a krogan scout who they tried to exalt.]] The process of creating it has left it in a state of UnstoppableRage, [[spoiler:due to krogan Blood Rage getting stuck into a feedback loop]], so the kett keep the first one locked up. [[spoiler:If Ryder doesn't save the other krogan scouts, they'll have to face more, the kett having decided in the mean time that an unstoppable berserker with a healing factor has its uses.]]
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* ''ComicBook/WonderWoman1987'': Dr. Lazarus' HardLight AI experiments are supposed to create constructs whose AI reflects the actions of whomever/whatever they're based on, however when it's used to create constructs based on superheroes those constructs are incredibly destructive, prone to casual murder and eager to attack other superheroes.
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* Downplayed in ''WesternAnimation/MyLifeAsATeenageRobot'' with [=XJ8=], the last FlawedPrototype made before Jenny. She not evil, but is so socially inept and gung-ho that [[HeroWithAnFInGood she's quite bad at being a good guy]].

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* Downplayed in ''WesternAnimation/MyLifeAsATeenageRobot'' with [=XJ8=], the last FlawedPrototype made before Jenny. She is not evil, but is [[NoSocialSkills so socially inept inept]] and gung-ho that [[HeroWithAnFInGood she's quite bad at being a good guy]].
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One small problem. The first test subject, AI, or robot off the assembly line isn't just a SuperPrototype, it's ''[[WithGreatPowerComesGreatInsanity completely insane.]]''

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One small problem. The first test subject, AI, or robot off the assembly line isn't just a SuperPrototype, it's ''[[WithGreatPowerComesGreatInsanity completely insane.]]''
insane]].''
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** Inverted in [[ComicBook/UltimateMarvel Ultimate Spider-Man]] with [[SpiderMan Peter Parker]] being ''bitten'' by the accidental prototype, and Norman Osborn attempting to replicate the success by injecting himself with the OZ Serum.

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** Inverted in [[ComicBook/UltimateMarvel Ultimate Spider-Man]] with [[SpiderMan [[ComicBook/SpiderMan Peter Parker]] being ''bitten'' by the accidental prototype, and Norman Osborn attempting to replicate the success by injecting himself with the OZ Serum.
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* Subverted in ''WesternAnimation/MyLifeAsATeenageRobot''. Though Jenny's sisters are prototypes, they are actually benevolent and try to help her whenever they can.

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* Subverted Downplayed in ''WesternAnimation/MyLifeAsATeenageRobot''. Though Jenny's sisters are prototypes, they are actually benevolent ''WesternAnimation/MyLifeAsATeenageRobot'' with [=XJ8=], the last FlawedPrototype made before Jenny. She not evil, but is so socially inept and try to help her whenever they can.gung-ho that [[HeroWithAnFInGood she's quite bad at being a good guy]].
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* Proto Man, but only in the ''WesternAnimation/MegaMan'' animated series. In the games he's more of an AloofBigBrother; he also has some kind of design flaw in his power plant or buster that can prove fatal, and means he has less health.

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* Proto Man, but only in the The ''WesternAnimation/MegaMan'' animated series. In the games he's more of an AloofBigBrother; he also has some kind of design flaw in his power plant or buster that can prove fatal, and means he has less health.cartoon [[AdaptationalVillainy revises]] Proto Man's character from a FlawedPrototype to one whose malfunctioning caused him to side with Dr. Wily.
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* The [=EB-AX2=] Graze Ein of ''Anime/MobileSuitGundamIronBloodedOrphans'' is the result of Gjallarhorn's secret avocation to bionic augmentation, it is equipped with triple Ālaya-Vijñāna Systems, [[DualWield dual]] [[AnAxeToGrind axes]], PileBunker and [[ThisIsADrill drill feet]], the price of such creation is the heavy toll on the [[WithGreatPowerComesGreatInsanity pilot's sanity]], [[spoiler: although the pilot, Ein Dalton, was [[RevengeBeforeReason already insane to begin with]].]]

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* The [=EB-AX2=] Graze Ein of ''Anime/MobileSuitGundamIronBloodedOrphans'' is the result of Gjallarhorn's secret avocation advocation to bionic augmentation, it is equipped with triple Ālaya-Vijñāna Systems, [[DualWield dual]] [[AnAxeToGrind axes]], PileBunker {{Pile Bunker}}s and [[ThisIsADrill drill feet]], feet]]; the price of such creation is the heavy toll on the [[WithGreatPowerComesGreatInsanity pilot's sanity]], [[spoiler: although the pilot, Ein Dalton, was [[RevengeBeforeReason already insane to begin with]].]]

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* In ''TabletopGames/BloodBowl'', Hakflem Skuttlespike was the first successful attempt by the masters of Clan Rigens to breed a player equal to Tarsh Surehands, the most talented [[RatMen Skaven]] to ever take to the Blood Bowl pitch. The plan to create an entire team of such players failed however, when the vicious and jealous Skuttlespike began slaughtering any and all subsequent creations that had the potential to equal or surpass his abilities.

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* In ''TabletopGames/BloodBowl'', ''TabletopGame/BloodBowl'', Hakflem Skuttlespike was the first successful attempt by the masters of Clan Rigens to breed a player equal to Tarsh Surehands, the most talented [[RatMen Skaven]] to ever take to the Blood Bowl pitch. The plan to create an entire team of such players failed however, when the vicious and jealous Skuttlespike began slaughtering any and all subsequent creations that had the potential to equal or surpass his abilities.abilities.
* The ''TabletopGame/DungeonsAndDragons'' sourcebook ''Book of Vile Darkness'' features the Vashar as an example of an utterly evil [[HumanSubspecies subrace of humans]]. The legend goes that when the gods created the first human, he immediately went looking for food, and chased down and killed an animal with his bare hands. The gods were disturbed, then morbidly fascinated as the man proceeded to eat the beast raw, then tear into the animal's carcass and fashion crude weapons from its bones and sinew. Then the first man turned and charged at the watching deities with his grisly weapons, screaming his first words, war cries and blasphemies. The gods effortlessly slew the human, but were so disgusted with their project that it was eons before they took another crack at humanity. However, some fiend spirited away the first man's remains and revived him - in some stories it was the work of a demon lord, in others a [[HornyDevils succubus]] who proceeded to bear the man's children. At any rate, the Psycho Human Prototype's descendants are the Vashar, [[AlwaysChaoticEvil Always Evil]] human sociopaths with no morals or taboos, united only by their goal of finishing their forebearer's attempt at [[KillTheGod deicide.]]
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* In ''VideoGame/BendyAndTheInkMachine'', this is [[spoiler: Bendy's]] origin. Joey Drew wanted living attractions to place in a theme park based off his studio's cartoons. Instead, he got... well, an ink monster. This "weird abomination" was noted to be a bit weird - which everyone chalked up to [[spoiler: being soulless, even before being locked away, chained to a chair, and forced to watch cartoons on endless loop. (As opposed to the other experiments, who started off as sane, normal humans rather than being originally [[{{Toon}} Toons]].)]] Now, the deranged character will indiscriminately kill anything in the studio.

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* In ''VideoGame/BendyAndTheInkMachine'', this is [[spoiler: Bendy's]] origin. Joey Drew wanted living attractions to place in a theme park based off his studio's cartoons. Instead, he got... well, Well, an ink monster. demon. This "weird abomination" was noted to be a bit weird - weird, which everyone chalked up to [[spoiler: being soulless, even before being locked away, chained to a chair, and forced to watch cartoons on endless loop. (As opposed to the other experiments, who started off as sane, normal humans rather than being originally [[{{Toon}} Toons]].)]] Now, the deranged character will indiscriminately kill anything in the studio.
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* ''Webcomic/AntiheroForHire'': [[spoiler:[[http://www.antiheroforhire.com/d/20050228.html Wizard]]]]

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* ''Webcomic/AntiheroForHire'': [[spoiler:[[http://www.antiheroforhire.com/d/20050228.html Wizard]]]]Wizard]]]] is revealed to be a psycho protoytpe of [[spoiler:the Sisters]].
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* ''WesternAnimation/{{Robotboy}}'' had Protoboy, Robotboy's older brother who was captured and turned into an OmnicidalManiac by Dr. Kamikazi. He would go to various lengths to attempt to prove he's Professor Moshimo's best invention/kill him, including [[GrandTheftMe switching his motherboard with his brother]] so he can get close to Moshimo and later threatening to kill Moshimo in a robot factory by pouring molten titanium on him unless Robotgirl offers to take his place. While he had a penchant for coming back to life after being blown up he's supposedly KilledOffForReal in the aforementioned factory.

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* ''WesternAnimation/{{Robotboy}}'' had Protoboy, Robotboy's older brother who was captured and turned into an OmnicidalManiac by Dr. Kamikazi. He would go to various lengths to attempt to prove he's himself as Professor Moshimo's best invention/kill him, including [[GrandTheftMe switching his motherboard with his brother]] brother's]] so he can could get close to Moshimo and later threatening to kill Moshimo in a robot factory by pouring molten titanium on him unless Robotgirl offers to take his place. While he had a penchant for coming back to life after being blown up up, he's supposedly KilledOffForReal in the aforementioned factory.
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* [[spoiler: Number One, "Cavil"]] from ''Series/{{Battlestar Galactica|2003}}''. [[spoiler: As the first of the new humanoid Cylons made by the Final Five, he exhibited bitterness at not being 100% machine, envy of his brothers and sisters (even entirely destroying the Sevens) and a deep desire for his creators to come around to his genocidal viewpoint to the point where he reprograms them to think they're humans and launches a genocidal attack on humanity.]] And those are just ''some'' their sins. Chiefly, this Cylon's actions resulted in the near genocide of the human race.

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* [[spoiler: Number One, "Cavil"]] from ''Series/{{Battlestar Galactica|2003}}''. [[spoiler: As the first of the new humanoid Cylons made by the Final Five, he exhibited bitterness at not being 100% machine, envy of his brothers and sisters (even entirely destroying the Sevens) and a deep desire for his creators to come around to his genocidal viewpoint to the point where he reprograms them to think they're humans and launches a genocidal attack on humanity.]] And those are just ''some'' their sins. Chiefly, this Cylon's actions resulted in the near genocide near-extinction of the human race.
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* In ''VideoGame/BendyAndTheInkMachine'', this is [[spoiler: Bendy's]] origin. Joey Drew wanted living attractions to place in a theme park based off his studio's cartoons. Instead, he got... well, an ink monster. This "weird abomination" was noted to be a bit weird - which everyone chalked up to [[spoiler: being soulless, even before being locked away, chained to a chair, and forced to watch cartoons on endless loop. (As opposed to the other experiments, who started off as sane, normal humans rather than being originally Toons.)]] Now, the deranged character will indiscriminately kill anything in the studio.

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* In ''VideoGame/BendyAndTheInkMachine'', this is [[spoiler: Bendy's]] origin. Joey Drew wanted living attractions to place in a theme park based off his studio's cartoons. Instead, he got... well, an ink monster. This "weird abomination" was noted to be a bit weird - which everyone chalked up to [[spoiler: being soulless, even before being locked away, chained to a chair, and forced to watch cartoons on endless loop. (As opposed to the other experiments, who started off as sane, normal humans rather than being originally Toons.[[{{Toon}} Toons]].)]] Now, the deranged character will indiscriminately kill anything in the studio.

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* The Derro from ''VideoGame/ForgottenRealms'' have believe they are the reincarnation of his god 'An avatar of murder'

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* The Derro from ''VideoGame/ForgottenRealms'' In ''VideoGame/BendyAndTheInkMachine'', this is [[spoiler: Bendy's]] origin. Joey Drew wanted living attractions to place in a theme park based off his studio's cartoons. Instead, he got... well, an ink monster. This "weird abomination" was noted to be a bit weird - which everyone chalked up to [[spoiler: being soulless, even before being locked away, chained to a chair, and forced to watch cartoons on endless loop. (As opposed to the other experiments, who started off as sane, normal humans rather than being originally Toons.)]] Now, the deranged character will indiscriminately kill anything in the studio.
* In ''VideoGame/BioShock2'', the Alpha Series was the first line of Big Daddies who, due to their bond with an individual Little Sister, would go either comatose or insane if their Little Sister was killed or saved by Tenenbaum.
* In the ''VideoGame/CrashBandicoot'' series, recurring villain [[KangaroosRepresentAustralia Ripper Roo]] is [[BigBad Dr. Cortex's]] very first [[UpliftedAnimal mutant animal soldier]]. Crash himself was a later attempt... and while ''he's'' a bit [[TheFool daft]], Roo is so [[AxCrazy nuts]] that he's always in a straitjacket ([[HandyFeet which, honestly, doesn't slow him down]]).
* ''[[VideoGame/FirstEncounterAssaultRecon F.E.A.R.]]'' oddly messes with this: the first prototype, [[spoiler:the Pointman]], is considered a failure, and it's the second prototype, [[spoiler:Paxton Fettel]], who's the one who causes problems. Interestingly, the first prototype isn't ''worthless'' by any measure, as he proves to be [[OneManArmy a far more efficient killing machine]] than the second prototype or the [[SuperSoldier Replica soldiers]] (and TheStinger goes as far as to
have believe [[spoiler:Genevieve Aristide suggest that he is, in fact, a success based on this]]), but the point of the program they are were created under was to create psychic commanders. [[spoiler:The Pointman]] has very lackluster psychic abilities, only enough to grant himself [[BulletTime unnaturally-enhanced reflexes]], while [[spoiler:Fettel]] is the reincarnation one with greater psychic powers to properly control the Replica battalions. The problem there is that it also leaves him very susceptible to [[spoiler:being taken control of his god 'An avatar of murder'by their mother; in-story he goes crazy ''twice'' under her influence, the second time forming the catalyst for the first game.]]



* ''[[VideoGame/FirstEncounterAssaultRecon F.E.A.R.]]'' oddly messes with this: the first prototype, [[spoiler:the Pointman]], is considered a failure, and it's the second prototype, [[spoiler:Paxton Fettel]], who's the one who causes problems. Interestingly, the first prototype isn't ''worthless'' by any measure, as he proves to be [[OneManArmy a far more efficient killing machine]] than the second prototype or the [[SuperSoldier Replica soldiers]] (and TheStinger goes as far as to have [[spoiler:Genevieve Aristide suggest that he is, in fact, a success based on this]]), but the point of the program they were created under was to create psychic commanders. [[spoiler:The Pointman]] has very lackluster psychic abilities, only enough to grant himself [[BulletTime unnaturally-enhanced reflexes]], while [[spoiler:Fettel]] is the one with greater psychic powers to properly control the Replica battalions. The problem there is that it also leaves him very susceptible to [[spoiler:being taken control of by their mother; in-story he goes crazy ''twice'' under her influence, the second time forming the catalyst for the first game.]]
* [[spoiler:Nebilim]] from ''VideoGame/TalesOfTheAbyss'': The first [[spoiler:human replica]], and [[CameBackWrong utterly insane]]. Then again, its creator wasn't [[{{Necromantic}} entirely stable-minded]] when he created it either.
* In the backstory to ''VideoGame/MegaManX'', Dr. Light feared that the eponymous X, the first robot with true free will, could become this, which is why he sealed him away for 30 years to test his morality.
** Played straight in ''VideoGame/MegaManUltra'', where [[spoiler:the same X]] was activated prematurely and went berserk, serving as the final boss.
** Inverted with Axl: he was the prototype for the transforming next-generation Reploids, yet he himself is quite sane, if possessed of a slight BloodKnight streak. It's the mass-produced versions that went psycho.
** Zero acted quite insane when he first appeared [[spoiler: because of TheVirus]]. But given his [[MadScientist creator]], it's unclear how much of this was intentional.

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* ''[[VideoGame/FirstEncounterAssaultRecon F.E.A.R.]]'' oddly messes with this: In ''Videogame/FiveNightsAtFreddys2'', the first prototype, [[spoiler:the Pointman]], is considered a failure, old animatronics are placed in storage as they are replaced by newer models. But they aren't deactivated, and it's will continue to stalk the second prototype, [[spoiler:Paxton Fettel]], who's the one who causes problems. Interestingly, the first prototype isn't ''worthless'' by any measure, as he proves to be [[OneManArmy a far more efficient killing machine]] than the second prototype or the [[SuperSoldier Replica soldiers]] (and TheStinger goes as far as to player at night.
* The Derro from ''VideoGame/ForgottenRealms''
have [[spoiler:Genevieve Aristide suggest that he is, in fact, a success based on this]]), but the point of the program believe they were created under was to create psychic commanders. [[spoiler:The Pointman]] has very lackluster psychic abilities, only enough to grant himself [[BulletTime unnaturally-enhanced reflexes]], while [[spoiler:Fettel]] is are the one with greater psychic powers to properly control the Replica battalions. The problem there is that it also leaves him very susceptible to [[spoiler:being taken control reincarnation of by their mother; in-story he goes crazy ''twice'' under her influence, the second time forming the catalyst for the first game.]]
* [[spoiler:Nebilim]] from ''VideoGame/TalesOfTheAbyss'': The first [[spoiler:human replica]], and [[CameBackWrong utterly insane]]. Then again, its creator wasn't [[{{Necromantic}} entirely stable-minded]] when he created it either.
* In the backstory to ''VideoGame/MegaManX'', Dr. Light feared that the eponymous X, the first robot with true free will, could become this, which is why he sealed him away for 30 years to test
his morality.
** Played straight in ''VideoGame/MegaManUltra'', where [[spoiler:the same X]] was activated prematurely and went berserk, serving as the final boss.
** Inverted with Axl: he was the prototype for the transforming next-generation Reploids, yet he himself is quite sane, if possessed
god 'An avatar of a slight BloodKnight streak. It's the mass-produced versions that went psycho.
** Zero acted quite insane when he first appeared [[spoiler: because of TheVirus]]. But given his [[MadScientist creator]], it's unclear how much of this was intentional.
murder'



* ''Franchise/MegaMan'':
** In the backstory to ''VideoGame/MegaManX'', Dr. Light feared that the eponymous X, the first robot with true free will, could become this, which is why he sealed him away for 30 years to test his morality.
** Alpha in ''VideoGame/MegaManBattleNetwork 3'' is the prototype of ''the Internet itself'' given form and AI.
** Played straight in ''VideoGame/MegaManUltra'', where [[spoiler:the same X]] was activated prematurely and went berserk, serving as the final boss.
** Inverted with Axl: he was the prototype for the transforming next-generation Reploids, yet he himself is quite sane, if possessed of a slight BloodKnight streak. It's the mass-produced versions that went psycho.
** Zero acted quite insane when he first appeared [[spoiler: because of TheVirus]]. But given his [[MadScientist creator]], it's unclear how much of this was intentional.
* ''[[VideoGame/ASuperMarioThing A Second Mario Bros. X Thing]]'' subverts this. Pandamona, the ''second'' sibling created by the Artist, is the insane one (even compared to the other cyclopses, [[QuirkyMinibossSquad most of which would also qualify for various degrees of insane]]). The eldest sibling, Science, has comparatively few screws loose ([[{{Cyborg}} literally]] and [[OnlySaneMan figuratively]]), which is why he is their leader.



* [[spoiler:Nebilim]] from ''VideoGame/TalesOfTheAbyss'': The first [[spoiler:human replica]], and [[CameBackWrong utterly insane]]. Then again, its creator wasn't [[{{Necromantic}} entirely stable-minded]] when he created it either.



* Alpha in ''VideoGame/MegaManBattleNetwork 3'' is the prototype of ''the Internet itself'' given form and AI.
* In ''VideoGame/BioShock2'', the Alpha Series was the first line of Big Daddies who, due to their bond with an individual Little Sister, would go either comatose or insane if their Little Sister was killed or saved by Tenenbaum.
* In ''Videogame/FiveNightsAtFreddys2'', the old animatronics are placed in storage as they are replaced by newer models. But they aren't deactivated, and will continue to stalk the player at night.
* ''[[VideoGame/ASuperMarioThing A Second Mario Bros. X Thing]]'' subverts this. Pandamona, the ''second'' sibling created by the Artist, is the insane one (even compared to the other cyclopses, [[QuirkyMinibossSquad most of which would also qualify for various degrees of insane]]). The eldest sibling, Science, has comparatively few screws loose ([[{{Cyborg}} literally]] and [[OnlySaneMan figuratively]]), which is why he is their leader.
* In the ''VideoGame/CrashBandicoot'' series, recurring villain [[KangaroosRepresentAustralia Ripper Roo]] is [[BigBad Dr. Cortex's]] very first [[UpliftedAnimal mutant animal soldier]]. Crash himself was a later attempt... and while ''he's'' a bit [[TheFool daft]], Roo is so [[AxCrazy nuts]] that he's always in a straitjacket ([[HandyFeet which, honestly, doesn't slow him down]]).
Is there an issue? Send a MessageReason:


* In the ''Franchise/CrashBandicoot'' series, recurring villain [[KangaroosRepresentAustralia Ripper Roo]] is [[BigBad Dr. Cortex's]] very first [[UpliftedAnimal mutant animal soldier]]. Crash himself was a later attempt... and while ''he's'' a bit [[TheFool daft]], Roo is so [[AxCrazy nuts]] that he's always in a straitjacket ([[HandyFeet which, honestly, doesn't slow him down]]).

to:

* In the ''Franchise/CrashBandicoot'' ''VideoGame/CrashBandicoot'' series, recurring villain [[KangaroosRepresentAustralia Ripper Roo]] is [[BigBad Dr. Cortex's]] very first [[UpliftedAnimal mutant animal soldier]]. Crash himself was a later attempt... and while ''he's'' a bit [[TheFool daft]], Roo is so [[AxCrazy nuts]] that he's always in a straitjacket ([[HandyFeet which, honestly, doesn't slow him down]]).
Is there an issue? Send a MessageReason:
None


* The Derro from Frogotten Realms have believe they are the reincarnation of his god 'An avatar of murder'

to:

* The Derro from Frogotten Realms ''VideoGame/ForgottenRealms'' have believe they are the reincarnation of his god 'An avatar of murder'
Is there an issue? Send a MessageReason:
None


* The Biolizard in ''VideoGame/SonicAdventure2'', the prototype UltimateLifeform.

to:

* The Biolizard in ''VideoGame/SonicAdventure2'', the prototype UltimateLifeform.UltimateLifeform to Shadow the Hedgehog. It's barely sentient and acts more like a beast on its primal urges. It's noted that the beast reacted violently when it came into contact with the Chaos Emeralds and ultimately had to be locked away in the central core of the [=ARK=] to avoid becoming an issue, and its violent nature was part of what resulted in the government deciding to pull the plug on the project. [[spoiler:And unlike Shadow, who ultimately has a change of heart, it fully goes ahead with attempting the ColonyDrop on the planet as planned by Dr. Gerald Robotnik]].
Is there an issue? Send a MessageReason:
factual correction


** The ''[[NamesToRunAwayFromReallyFast Indominus rex]]'' from ''Film/JurassicWorld''--created to be the strongest dinosaur ever, she escapes from her cage and goes on a killing spree just because she can. [[spoiler:It then turns out that this was intentional as part of a plan to turn dinosaurs into living weapons for the military.]]

to:

** The ''[[NamesToRunAwayFromReallyFast Indominus rex]]'' from ''Film/JurassicWorld''--created to be the strongest dinosaur ever, she escapes from her cage and goes on a killing spree just because she can. [[spoiler:It then turns out that this [[spoiler:She was intentional created as part of a plan to turn dinosaurs into living weapons for the military.]]

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