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** ''VideoGame/FinalFantasyXIV'' has [[spoiler:Zenos yae Galvus, introduced in ''Stormblood''. He is an absolute terror on the battlefield, and so persistent on fighting the [[PlayerCharacter Warrior of Light]] that not even his own death stops him: after the final boss fight that ends in what should've been his death, he uses his Resonant powers to transfer his soul into a nearby soldier's body, then finds and chases away the Ascian that had taken over his original body so he can take it back.]]
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* The Queen of Hearts' Executioner in ''VideoGame/AliceMadnessReturns'' is a giant, undead card guard wielding a scythe who will relentlessly pursue Alice once she enters the castle. At most, her weapons -- from the [[ImprobableWeaponUser acid-lobbing teapot]] to the [[MoreDakka pepper-grinder gun]] only make him stumble. [[spoiler: A bite of familiar cake brings the whole chase to a very satisfying end.]]
* The Alien in ''VideoGame/AlienIsolation'' is almost completely invincible to everything that the player has. It is incredibly fast (much faster than [[PlayerCharacter Amanda]]), and if it grabs Amanda then it's [[OneHitKill game over]]. The only options are to avoid it as best as possible and, later in the game, drive it off temporarily with a flamethrower. Of course, even with the flamethrower, [[ArtificialBrilliance it learns to adapt if over-relied on]].
* ''VideoGame/AmnesiaTheDarkDescent'' has a collection of {{Humanoid Abomination}}s that serve only to pursue and murder the player. So you've blocked the monster's only entrance with about fifteen crates and plenty of furniture? '''''[[https://www.youtube.com/watch?v=VkWr_CBSxGI&t=180s Good luck with that.]]'''''
* ''VideoGame/{{Arknights}}'': Executor Federico of the Laterano Notarial Hall is depicted as this, befitting his TerminatorImpersonator image.
** His resume lampshades this.
--->''[[BeCarefulWhatYouWishFor Be careful what you wish for]], because he really can accomplish things that border on absurdity or impossibility.''
** In the chapter ''Survival Notorization'' of the event Operational Intelligence, he is seen pursuing the young huntress Vermeil through her homestead in Siracusa, disarming booby traps and catching arrows coming his way without much trouble. At the end of the event he offered to help her fight off the Ursus mercenaries coming for her, and since both of them made it to Rhodes Island as operators it's safe to assume he killed them all.
** His profile states that executors like him are only deployed on the most challenging of missions. His work records included: killing 41 hardened criminals to deliver an item, damaged six buildings to shutter a company, killing a chief executive of a city state guard unit over a money dispute, and almost caused a war when fulfilling the wishes of the contracted citizens.
--->''Most of Executor's mission record is like this. It is clear that the Notarial Hall deploys its executors only to the most challenging of missions.''
* ''Franchise/AssassinsCreed'': Altaïr is a mortal man. Altaïr is [[BlatantLies apparently susceptible to regular weapons]] such as swords, arrows, daggers, and [[ArsonMurderAndJaywalking small thrown rocks]]. Altaïr will slaughter his way through an ''ambush'' of roughly fifty EliteMooks in about fifteen to twenty minutes without bothering to rest afterwards because he has sworn to [[NeverSayDie remove you from this mortal coil in a timely fashion]], and anything that gets in his way is just one more thing to cut down. There is a reason he is a MemeticBadass, and there is a point where a "normal person" just can't be defined as a {{Determinator}} anymore. For Altaïr, that point is probably about when he mercilessly cuts fifty-plus men into chunks (or runs them through, if he wants to spice things up), including the archers who are ''shooting him as he fights''. Then, just to make completely certain that you know he's an Implacable Man, he goes straight from the trail of bodies to TheDragon, stopping only to accuse the man of treason and kill ''another'' twenty Elite Mooks before finally taking on TheDragon one-on-one and administering a fatal CurbStompBattle. Yes, that's right. Altaïr [[CurbStompBattle Curb Stomps]] ''TheDragon'' after having spent probably the last half-hour fighting off over ''seventy soldiers''. If you see [[http://i34.tinypic.com/bedhmq.jpg this man]] heading in your direction, DontAskJustRun.\\\
Whether he's aiming for you or not, it generally seems like a good idea to flee from a man [[FightMagnet whose very existence]] tends to incite bloody battles to the death that often rage across multiple streets in a frenzy of blades and blood. You might not be his target, but you should probably get out of his path. You should start running if you see Altaïr, but...[[ParanoiaFuel chances are you won't see him]] until he rams a metal spike into your neck.
** The same goes for Ezio from the sequel. The man fights his way into the Vatican, merrily slaughtering the Pope's [[EliteMooks personal guard]] as he goes. He then shrugs off a blast from said Pope's [[spoiler: {{Magitek}} staff]] (which incapacitates the other dozen or so people present), engages in a [[spoiler: {{Magitek}} Wizard's Duel]] with said pontiff, is [[spoiler:STABBED IN THE GUT by same]], before sucking it up and going on to [[spoiler:beat the aforementioned most powerful man in Europe to a bloody pulp with his bare hands]]. There is a reason he is named only one breath after Altair when someone talks about the greatest Assassins of all times.
** Shay from ''VideoGame/AssassinsCreedRogue''. The Assassins (the deadliest people on the planet) try to kill him and ''fail miserably''.
* Asura from ''VideoGame/AsurasWrath'', patron saint of UnstoppableRage. He gets killed ''four'' times, and every single time he escapes the underworld, even angrier than before. Hell, the only thing that kills him off for good [[spoiler: is killing Chakravartin, who is basically God!]]
* The first game with an Implacable Man was ''VideoGame/{{Berzerk}}'' and Evil Otto, who shows up if you are slow in clearing the room of robots. Not only was he invulnerable, but could pass through the electrified walls that would kill anything else that touched them, including the robots that were also trying to kill the player. Otto would also destroy any robots that were in his way, and in some rooms the only way to get the bonus points for killing all the robots was to lead Otto through a walled off chamber in which the last robot was hiding. Otto would gradually speed up over time, and instantly go to maximum speed (twice as fast as the player) once all robots in a room were destroyed, making death at his hands unavoidable unless the player was very close to an exit.
** In the sequel to Berzerk, Frenzy, Otto could actually be killed by four laser shots (either from players or robots). Every time he died, however, he would return from the same spot he spawned one second later, moving slightly faster than before. Killing him was worth quite a few points, but his movement pattern (bouncing vertically like a ball viewed from the side, even though the game actually used a top down perspective) made scoring hits very difficult unless directly above or below him, and this was the most dangerous place to be while fighting him due to the horizontal screen and the bouncing movement making Otto able to cover vertical distances much more quickly. It didn't help that missing Otto with a laser blast could result in the player's death from his own beam, due to new laser-reflecting walls present in the sequel. Finally, Frenzy included some special rooms, including the nightmare inducing "Mama Otto" room, dominated by a giant (but thankfully motionless) Evil Otto. Until you set it off...
* ''VideoGame/BinaryDomain'': Subverted with the rank and file robot mooks; sure, they'll keep shooting no matter how many limbs you blow off, but destroy their head and they revert to their default 'protect humans' mode, convincing them to spare you and kill the other robots[[note]]Just don't expect their backup systems to do more than walk and fire in the general direction of robots from their secondary sensors[[/note]].
* The ''VideoGame/BioShock'' series has one for each setting:
** Big Daddy in [[VideoGame/BioShock1 Rapture]] and The Songbird in [[VideoGame/BioshockInfinite Columbia]]. The former, an [[NinjaPirateZombieRobot underwater cyborg steampunk Papa Wolf]], is a loose example as he won't attack you unless you provoke him. You might assume from his dense armor that Big Daddy can't keep up a hot pursuit. You would be mistaken. There are several models throughout the game, and two variations (one with a drill, and another with a rivet gun.)
** The Songbird, a giant robotic sparrow who patrols the tower [[LivingMacGuffin Elizabeth]] is imprisoned in. It's only goal is to return Elizabeth to her gilded cage, meaning it's possible to appease Songbird by simply handing her over. It takes the entire game to finally turn Songbird to scrap metal.
** And then there is the Motorized Patriot, who in his introductory video is actually described as being this, He feels no pain, he does not falter, no sense of self-preservation, he has no CranialProcessingUnit, so really, you can shoot at him until he's dead but he will not stop.
* Hedrox in ''VideoGame/BloodRayne'' is an Implacable ''Vampire''. He is a beastial vampire monster with large claws and extremely powerful regenerative powers that make him immune to bullets and any blade damaged done to him heals very fast. Worse, if he gets dismembered, then several clones will emerge from the severed parts and create new Hedrox's that will keep pursuing you. [[spoiler:The only way Rayne can beat him is thinking outside the box and drop him into water, which burns vampires like acid. Even then, one of his copies survives and it takes being incinerated by the demonic BigBad to finally destroy him.]]
* Wilhelm in ''VideoGame/BorderlandsThePreSequel''. Most characters, when they run out of health, go into "Fight For Your Life mode", where they slump to the ground and frantically try and gun down targets until they either bleed out or score a kill and earn a "second wind". Wilhelm's "Dreadnought" skill tree, however, has a skill called "Termination Protocols". With this, instead of a normal FFYL, Wilhelm gets a shorter period of full activity where he keeps walking and killing normally, plus electrifies the area around him -- and if he fails to kill anyone in that time, he sets off a huge, if low-damage, explosion as a final "screw you" -- and can score a Second Wind off any of these.
* ''VideoGame/BrainDead13'': Fritz. No matter where you are, no matter how much distance you put between you and him, no matter what you have just done to him, no matter how many times he falls prey to the castle's other dangers and his own vast armament, Fritz is almost always five seconds away from killing you.
* Solus from ''VideoGame/{{Breakdown}}'' is indestructible to the point where all you can do is run, dodging laser traps only to see him just ''walking through them'' -- these laser traps would kill you the second you touch them, and yet he just walks straight through them without even a burn mark to show for it.
* ''VideoGame/ChzoMythos'' series:
** The Welder
** The invincible Tall Man. Depending on his mood, he'll just walk towards you, or teleport Manga/DragonBall Z style and butcher you effortlessly.
* ''VideoGame/CliveBarkersUndying'': The Covenant siblings cannot be killed by any mortal weapon, only with the Scythe of the Celt. Even then, Lizbeth's head snarls and spits at Patrick before he lights it on fire and throws it off a cliff.
* Scissorman from the ''VideoGame/ClockTower'' series, and the Subordinates from ''VideoGame/ClockTower3''. The stalkers from ''Ghost Head/The Struggle Within'' as well, zombies excluded.
* In ''VideoGame/CommandAndConquer'', Kane has survived being shot at by a giant space laser, and also being run through by a piece of debris. He comes back for yet another sequel. Where he gets shot by the space laser ''again'' and is [[VillainousBreakdown very angrily surprised]] when he finds out his followers thought it was going to stick this time.
* The King Tiger Tank in ''VideoGame/CompanyOfHeroes''. Its armor is so thick that no Allied tank can penetrate its frontal armor. It has a really powerful gun, multiple machine guns, and max veterancy. The only way to defeat it is to surround it with multiple tanks or to use its natural enemy in real life: bridges. Destroying a bridge with demo charges will oneshot it, just like anything else. There is a reason why calling this into battle is the last ability received on the [[http://www.gamereplays.org/companyofheroes/portals.php?show=page&name=company-of-heroes-terror-doctrine-units-abilities-strategy-tactics-guide&st=3]] terror doctrine commander tree.
** The lesser known Jagdpanther tank destroyer is also a bitch to kill.
* ''VideoGame/TheCrookedMan'': The titular character will ''never'' desist from chasing David until the good ending of the game is reached. He can't be killed before then due to [[spoiler: already being dead]].
* The Pursuer in ''VideoGame/DarkSoulsII'' "will not rest until his target is slain". He backs this up, particularly in ''Scholar of the First Sin'', by constantly dogging your steps, popping up again and again no matter how hard you put him down. In Scholar's NewGamePlus you can end up killing him nine times, more if you use bonfire ascetics. (That being said, part of this is a mistranslation from the original Japanese, in which the Pursuer is a member of an organisation of similar warriors, who are presumably the ones harassing you; in English, his boss soul's text implies he is a lone warrior with a particular grudge against those with the Undead Curse.)
* Combining this trope with RasputinianDeath, the Gibbering Prophet of ''VideoGame/DarkestDungeon'' is certainly made of this trope. He continuously warned the townsfolk of the Ancestor's evil and for being a harbinger of doom, much to the annoyance and worry of the Ancestor. The prophet faced StockPunishment, was thrown into icy waters to freeze and drown, and was stabbed multiple times with various weapons, but every time the prophet would come back and continue to decry him, and wear the knives and what remained of the pillory to taunt the Ancestor. It took a HannibalLecture and a showing of what exactly the Ancestor had planned to finally break the prophet, causing him to GoMadFromTheRevelation and end up becoming a boss you'd have to face.
* In addition to what has been mentioned about ''TabletopGame/Warhammer40000'', the ''Dark Crusade'' expansion to ''VideoGame/DawnOfWar'' gives [[OurElvesAreDifferent Eldar]] Fire Dragons the effective mass of super-heavy tanks without compromising their agility. Although they do not have the durability of most other examples on this page, the not-too-shabby health they possess results in a bunch of base-wreckers that can sprint through air strikes, artillery, orbital bombardment and God-Emperor knows what else without being tossed around like most other infantry. Yes, that list of infantry includes [[OurOrcsAreDifferent Da Ork Warboss]]. They form a point of contention regarding Eldar imbalance.
* The killers in ''VideoGame/DeadByDaylight'' are unable to be harmed or damaged in any way, although the survivors are free to disorient and slow them down using the environment. Even when caught in their own BearTrap, the Trapper just opens it up and sets it aside.
* ''VideoGame/DeadSpace'' has The Hunter, aka the Regenerator Necromorph, an artificial Necromorph created by the ship's resident MadScientist that steadily pursues you through the ship over several chapters. Notable for not only enduring all damage the player can inflict and brush off the effects of being cryogenically frozen, but after luring it into the path of a ship's thrusters and testing them, ''it can still be seen trying to crawl towards you as it melts to death''.
** ''VideoGame/DeadSpace2'' does this again through The Übermorph in the final chapters; whilst it is still relentless and able to regenerate limbs in moments, it is presented as an Elite Mook by sudden unexplained appearance (and by it functioning primarily as an invincible mook rather than a plot device like the aforementioned Hunter).
** ''VideoGame/DeadSpace3'' ups the ante by throwing ''several'' Regenerators at Isaac in one level. He remarks that he [[DemonicSpiders REALLY hates those things]]. They're put down for good when the docking bay vents and they wind up spaced (this doesn't kill Necromorphs, but a Necromorph floating in perfect vacuum isn't in a position to kill anyone).
* ''VideoGame/{{Destiny}}'' has The Vex, basically a race of Terminators that can keep coming after you even if you blow their heads clean off. While they can be killed, it's implied that destroying their physical constructs doesn't really do much to slow them down since [[spoiler: they can alter the flow of time and just call more troops in from the past, present, or future to throw at you. There is also the experiment they were working on in the Vault of Glass, which would have made their own existence and dominion over the universe a ''law of reality'', taking them up to true implacability.]]
* In the ''VideoGame/DevilMayCry'' series, enemies on [[IdiosyncraticDifficultyLevels Dante]] [[NintendoHard Must Die and higher difficulties]] have a [[SuperMode Devil Trigger power]] that they can use, making them nearly immune to flinching and much harder to kill. Vergil in the third title represents the Implacable Man ideal more accurately. When he uses his Devil Trigger (on ''any'' difficulty, BTW), he doesn't flinch from attacks, [[NighInvulnerability takes them without being scratched at all]] and [[HealingFactor regenerates health]]. While he can be knocked out of it, showing the state to be merely a brief flirtation, it is hard enough to do so. When he assumes the Super/Desperation Devil Trigger in the final fight, he can't be knocked out of it, but he does halt after some time, though not before regenerating at a higher rate than in his normal Devil Trigger.
** This is justified in that when ''you'' DT, you get the stun resistance yourself also, as well as the regenerative factor.
** Enemies? Dante gets impaled with his own sword in every installment. This somehow fazed him only the first time it happened. Must have been the novelty.
* In ''VideoGame/DisasterDayOfCrisis'', Ray is practically this -- he survives several natural disasters while fighting an elite former special forces unit, and he just still keeps coming after them on his own out of sheer willpower to save Lisa. Major Evans also has this trait, taking an ungodly amount of bullets to the face (and calls their first fight a ''draw'' after he takes so many bullets!), mans a Metal Gear expy while still taking even more bullets (or rockets) to the face, and can give Ray a hand-to-hand battle before [[spoiler:Colonel Haynes finally shoots him square in the forehead. That guy must have a really special gun]].
* The Cyberdemon in ''VideoGame/{{Doom}}'' can mow through masses of lesser mooks with its rocket launcher and {{One Hit Kill}}s the player unless your health and armor are at nearly 200%. It takes roughly 400 bullets to be put down, which is twice as many as you can carry without a backpack, and it's resistant to missiles[[note]] Specifically, it is immune to the splash damage that is normally what causes most of a rocket's damage output[[/note]], which are unfortunately the only kind of ammo that you'll find in its lair. The fact that you don't have the {{BFG}} at that point doesn't help. Not to mention it had better stats (health, speed, pain chance) than the final boss, who shows up one whole episode later.
* This trope is completely flipped on its head in ''VideoGame/Doom2016'' and ''VideoGame/DoomEternal'', wherein various [[EncyclopediaExposita Codex]] entries make it abundantly clear that [[PlayerCharacter you]], the Doom Slayer, are ''by far'' the most [[TheDreaded horrifying]] and [[OneManArmy unstoppable]] opponent that Hell has ever seen. Any attempt by any of Hell's leaders to bargain or plead with the [[NoNonsenseNemesis Slayer]] is silenced without a moment's hesitation. One level in the former game features the corpse of a {{Kaiju}}-sized demon, which the nearby lore tablet explains the Doom Slayer killed ''by himself'', armed with nothing but ''an ordinary sword and shield''.
* In ''VideoGame/DragonAgeOrigins'', the Arcane Warrior when built correctly becomes a virtual god. With right spells and a good armor, they will take practically zero damage against most enemies, even High Dragons. The rest of your party may be dead, including your tank, but Arcane Warrior will keep fighting. If you also give him/her Spirit Healer as a second specialization s/he will be practically immortal.
** [[PlayerCharacter The Warden]] is seen as this by many of their enemies. It doesn't matter what the enemies try in order to stop the Warden, they always keep coming. In fact, they even try to stop them by trapping them in the Fade in two different ocassions. They fail. Both times. Completely.
** [[ActionGirl Aveline]] from ''VideoGame/DragonAgeII'' is the game's resident StoneWall. In addition to the usual warrior skills, her special tree has skills which make her immune to every status effect in the game, including critical hits. After taking enough of this, the only thing that can stop her is magically lifting her from the ground and confining her in a telekinetic prison, and she has better-than-even odds of saving against it. An illustration: in a contest between [[UnstoppableForceMeetsImmovableObject Aveline and a charging Ogre]] (read: horned sixteen foot wall of muscle), when the two meet, Aveline will still be standing. The ''Ogre'' will be on the ground.
** ''VideoGame/DragonAgeInquisition'' has the Champion [[PrestigeClass specialization]] for warriors, focused on tanking. Along with abilities that boost their defensive and guard-building abilities, they have an activated ability that makes them completely invulnerable for a short period and a passive that makes them completely invulnerable [[CriticalStatusBuff when they would otherwise be reduced below 5% health]].
* In ''VideoGame/TheElderScrollsOnline'', BigBad [[OurGodsAreDifferent Daedric Prince]] [[TheCorrupter Molag]] [[GodOfEvil Bal]] creates an implacable BadassArmy out of the Xivkyn, a form of [[OurDemonsAreDifferent lesser Daedra]] Bal created by combining the [[GiantMook massive]] and [[EliteMooks powerful]] but unruly and [[ChronicBackstabbingDisorder untrustworthy]] Xivilai with the {{Proud Warrior Race|Guy}} [[TheLegionsOfHell Legions Of Hell]] Dremora (who refer to themselves as the "Kyn" in the Daedric language). The result is an implacable fighting force which very nearly takes over Mundus.
* ''VideoGame/{{Fallout}}'':
** ''VideoGame/Fallout2'':
*** There's Frank Horrigan, a 12 foot super mutant in PoweredArmor who laughs at the idea that plasma fire can kill him. It takes concentrated fire from several turrets and an Elite Mook squad to even have ''even'' chances.
*** The Great Khans are an entire organisation of this. Go ahead: march into their base and slaughter them to the last man -- this has happened twice in their history. There is always some survivor who runs off and reforms the Khans to continue their raiding.
** In ''VideoGame/Fallout3'', one can find audio logs detailing the experiments in Vault 92 aimed at using subliminal messages and infrasound to create obedient super soldiers incapable of feeling pain. The experiments were partially successful, with the test subjects requiring upwards of 20 bullets to put down, but also becoming violently unstable and eviscerating each other with their bare hands.
** ''VideoGame/FalloutNewVegas'':
*** Joshua Graham, the former [[TheDragon right-hand man]] of Caesar. NCR snipers have reported confirmed kills on him ''multiple'' times, only for him to reappear just fine a few days later. He was at Boulder City when the Hanlon's rangers blew it up. When he failed to win the Battle of Hoover Dam for the Legion, Caesar ''[[ThereIsNoKillLikeOverkill set him on fire and threw him into the Grand Canyon]]'' to ensure he'd stay dead. Then, just in case that didn't do it, Caesar sent assassins down after him to finish the job. [[AssassinOutclassin That didn't do it either]]. In ''Honest Hearts'', he has a Damage Threshold of 50, which is more than the biggest, heaviest, tankiest Power Armor in the game provides. His own armor is just a standard bulletproof vest worn over his normal clothes, which provides only 15 DT.
*** The [[PlayerCharacter PC]] "The Courier" also qualifies: at the start of the game, they are shot twice in the head by a 9mm at point-blank range (granted, [[LittleUselessGun you probably won't be able to kill anything with two shots from a 9mm either]]). After spending a few days in the local clinic, they get back up march out into the Mojave and slaughter everything in their path. With the DLC's included, they also have their brain, heart and spine removed and are actually better off for it (they have synthetic replacements installed), get stranded in a poisoned city filled with other unkillable monsters (see below), and simply walk away with all the guns and gold they can carry.
*** The Ghost People of ''Dead Money'', after years of exposure to the toxic cloud, are nigh-immortal. They silently stalk you through the city, unable to talk through the heavy clothing they wear, dragging travelers off to beneath the city to do... God only knows what to them. After being left alone for 30 seconds, a 'killed' Ghost Person will simply start up again like a wind-up Terminator. The only way to stop them is the four Ds: Disintegration, Decapitation, Dismemberment, and Dog (who eats them). And in order to get into the Sierra Madre Casino, you have to start up the Gala event. Which attracts the attention of every single Ghost Person in the city, including the ones underground. Have fun.
* In ''VideoGame/FarCry3'' Jason Brody makes just about everyone who isn't on his side assume that he is invulnerable [[spoiler: because Vaas' otherwise lethal bullet was deflected by a cigarette lighter. Naturally, everyone who knew about Brody's apparent death jumped to the extremely logical conclusion that he just came back to life]].
-->'''Vaas:''' The thing is... alright, the thing is: I killed you once already... and it's not like I am fucking crazy.
** Technically Brody does fulfill this trope, as Vaas foiled his attempts on revenge [[spoiler: three times: first by shooting Jason, second by kicking him into deep water tied to a cement block, third by stabbing him with a machete. Brody survives all of them and manages to kill Vaas (just a few minutes after being stabbed), where he (finally) falls unconscious and presumably nearly dies.]]
* A tradition of ''VideoGame/FatalFrame'' series thus far goes as this: Any hostile spirit that serves as the BigBad of the game is also unbeatable until the designated final battle against said ghost. This includes Kirie in ''[[VideoGame/FatalFrameI I]]'', Sae and the Kusabi in ''[[VideoGame/FatalFrameII II]]'', Reika in ''[[VideoGame/FatalFrameIII III]]'', Sakuya in ''[[VideoGame/FatalFrameMaskOfTheLunarEclipse IV]]'', and Ouse in ''[[VideoGame/FatalFrameMaidenOfBlackWater V]]''. (That said, Sakuya has a twist: You DO battle her weaker form early on and must defeat her to proceed, but then she TurnsRed and plays this trope straight.)
* Zouken Matou from ''VisualNovel/FateStayNight''. [[spoiler:He actually gets 'killed' so often and eventually so effectively by Kotomine that he moves his soul into the Crest Worm that was in Sakura's heart, at which points she rips it out. Then crushes it. And he's ''still'' not dead.]] Also Kotomine, who had his [[spoiler: heart ripped out and was still around two days later to kick Shirou's ass despite the latter's body currently turning into swords]].
* Alma from ''[[VideoGame/FirstEncounterAssaultRecon F.E.A.R.]]''. You actually do face her head-on at the end of the game... but even then, you don't so much defeat her, or hurt her, as vaguely annoy her into leaving you alone [[spoiler: by detonating a nuke on her head.]]
** It also appears to be [[spoiler:genetic. It does not matter ''how'' many clones, helicopters, or psychic phenomena you throw at the Point Man. He'll tear through it all without so much as grunting]]
* The ''Franchise/FinalFantasy'' series has various examples:
** ''VideoGame/FinalFantasyVII'': Sephiroth. [[DoomedHometown Destroying Cloud's hometown]] [[OutOfTheInferno and walking through the ensuing flames without a scratch,]] [[KillTheCutie killing]] [[LastOfHisKind Aeris]], [[WithGreatPowerComesGreatInsanity ascending to near godhood]], [[TheEndOfTheWorldAsWeKnowIt and trying to destroy all life]] shows how far he'll go to prove his desire to [[GodhoodSeeker "inherit" the planet he feels is rightfully his.]]
** Subverted with [[SpiderTank X-ATM 092]] from ''VideoGame/FinalFantasyVIII''. Despite its self-recovering system and its ability to ambush you during an escape from Dollet in a limited time that make you think you need to run, this giant spider can be destroyed for real, and you're encouraged to do so because of some extra See-D ranks. You just need enough firepower to blow it up before it can fully recover itself.
** ''VideoGame/FinalFantasyX'': Auron, a [[TheMentor veteran Guardian]] and BadassLongcoat [[spoiler: who died years before]]. He didn't like that, so [[spoiler: he ''willed himself'' back into existence]].
** Llednar from ''VideoGame/FinalFantasyTacticsAdvance'' received no damage at all if you try to attack him with ''anything''. [[spoiler:It was actually because of the "Fortune" law, so Ezel created an [[AppliedPhlebotinum antilaw card]], making Llednar vulnerable to any attacks.]]
* In ''[[VideoGame/DissidiaFinalFantasy2015 Dissidia Final Fantasy NT]]'', [[VideoGame/FinalFantasyVII Sephiroth]]'s playstyle is based around relentlessly chasing down his opponents. He can dash-cancel many of his attacks, and his EX Skill, JENOVA, slows down nearby opponents, making them easier to pursue.
* The Black Knight/[[spoiler:General Zelgius]] from ''Franchise/FireEmblem'' definitely qualifies. He's invincible to all but the main character's ''BFS'' (which you get in the last few chapters of the game...), at least in the first game. [[spoiler:A whole castle falls on him, and he comes back just fine in the sequel.]]
* All/most of the animatronics in ''Franchise/FiveNightsAtFreddys'' are this. In fact, the only thing that could stop most/all of them is getting scrapped/destroyed/burned alive. Honorable mentions go to:
** Freddy, Bonnie, Chica, Foxy, Golden Freddy and the Puppet try to kill the guard since 1983. They stopped it in 1993, only because the restaurants closed down for 30 years.
*** Bonnie the Bunny. In 1987, he lost his face and arm, but he ''still'' tries to kill the guard.
** The Mangle. It is a victim of '''''gigantic''''' BodyHorror, yet it still somehow walks. By 2023, the only thing found is it's mask, so you can imagine how much it took to finally stop it.
** The main four animatronics in ''VideoGame/FiveNightsAtFreddysSisterLocation'' are extremely desperate to escape the establishment. They eventually merge their wires and endoskeletons to become Ennard. And how do they escape once they became Ennard? ''Rip out our organs and skeleton only to replace it with themselves.''
*** They were stopped ''decades'' later by being burned alive.
* ''VideoGame/{{Gloomwood}}'': One of the things that makes the Goatman so dangerous is the fact that it will ''relentlessly'' chase the player around the area it's in. Lock the doors? It'll smash them down. Go to another floor? It will slowly home in on you and find you eventually. Try to run? It will make a mad dash forward and quickly begin to outrun you. It can be brought down in combat, but that's far easier said than done -- [[MadeOfIron it can survive upwards of]] ''[[MadeOfIron ten]]'' [[MadeOfIron shotgun blasts point-blank]] in a game where most enemies go down in a single shot.
* Aquiles from ''VideoGame/FobiaStDinfnaHotel'' is a mutant monstrosity who repeatedly comes after you, again and again, no matter how many times you try to put him down. He's fought as a boss around 6 times, and it takes [[DIsneyVillainDeath dropping him into a chasm of acid]] to kill him for good.
* Kratos from ''VideoGame/GodOfWar''. And when he does die, he just slaughters his way back to the land of the living.
** In ''VideoGame/GodOfWarPS4'', he finally meets his match in the Stranger, who pursues him across the Nine Realms and ''never'' gives up; even killing him ''three times in a row'' can't stop him, and the only way to progress the story is to toss him somewhere he can't get out of for a while, like the bottom of a ravine or Hel.[[spoiler: He's Baldur, the Aesir given CompleteImmortality by his mother's spell; until the enchantment is broken by him accidentally cutting himself on a mistletoe arrowhead, the worst anyone can do is toss him around.]]
* You as Aldo Trapani in ''VideoGame/TheGodfather: The Game'', despite his not-so-invulnerability in-game. Hundreds of enemy mobster corpses? Those [[TotallyNotACriminalFront totally-not-criminal establishments]] converted to the Corleone cause? All stepping stones on the RoaringRampageOfRevenge leading to Don Emilio Barzini, the man who [[YouKilledMyFather ordered your father's death]].
* Jake and Francis Fratelli in ''VideoGame/TheGoonies (NES)''. The sequel introduces a third brother, but he can at least be defeated.
* Assassins can become this in [[PlayerVersusPlayer PvP]] matches of ''VideoGame/GuildWars'' when they use their Shadow Form enchantment. It makes them completely ''invincible to every attack or spell in the game''. If an Assassin using this skill targets you in a match, your only option is to run. Unless you have a signet that can remove enchantments...
* ''VideoGame/HalfLife'':
** The G-Man is a variant: you don't fight him, but he does follow Gordon Freeman all over the place, finding routes through places that Gordon must fight through and getting to spots before Gordon can. However, if you do feel like popping off a few rounds at him before he disappears round whatever corner, they simply bounce off with the bullets-on-metal sparks effect and sound (at least in the original ''VideoGame/HalfLife1''; in ''[=HL2=]'', like all important or allied [=NPCs=], he simply cannot be hit by weapons).
** Gordon Freeman, the "[[RedBaron One Free Man]]" himself. By ''VideoGame/HalfLife2'' he is [[TheDreaded feared]] as a OneManArmy by the Combine, and [[HopeBringer worshipped as a hero]] by the humans in equal amounts.
* ''VideoGame/HauntingGround'': The game's main claim to fame is that the player is chased by this type of individual once a chapter. These beings have different approaches to chasing the heroine, such as their attention span or diligence in finding her hiding spots. The best one can do before their boss fight is to run away, or knock them out via dog-mauling or alchemic munitions.
** Debilitas (The Caretaker) serves as an introduction to the game's premise. He's not as durable or persistent as later stalkers can be, and can be knocked out somewhat more easily. That being said, he shouldn't be underestimated.
** Daniella (The Maid) is made of this trope; she is incredibly difficult to knock out, and when that's achieved, she gets up quite quickly. She will relentlessly stalk Fiona, pretend to not know where her hiding spots are and will purposely lock Hewie in rooms and attack him to draw Fiona out if she genuinely has no idea where she is. This is even lampshaded during her Boss Fight if she's knocked out:
---> '''Fiona:''' ''[in journal]'' Even ''that'' didn't stop her?! What is she, the maid from hell?!
* ''VideoGame/HelloKittyRollerRescue'' has this for a final boss; to win, you have to stall it until Keroppi can destroy it with a WaveMotionGun.
* Death (the security guard boss) from ''VideoGame/HouseOfTheDead 3'' shows up not just once but TWICE! One of the characters comments on its one-track mind and persistence.
* ''VideoGame/{{Iconoclasts}}'' has two examples, late in the game near the rocket.
** While you are trying to get the elevator working, [[spoiler:Black]] can not be stopped. Defeating the boss is not an option; you must fix the elevator and get out of there.
** A more classic version is [[spoiler:Elro, going up against Lawrence. Lawrence can shoot Elro, throw knives, punch him if he gets too close, but unless he runs out of HP, Elro keeps. On. Coming. Good thing you're playing Elro, and your job is just to No-Sell Lawrence's attacks while you keep marching up and stabbing him.]]
* The eponymous heroine of ''VideoGame/{{Iji}}'' winds up viewed this way by the enemy troops, according to their logs -- whether or not you're playing a pacifist run.
* [[NamesToRunAwayFromReallyFast The Beast]] from ''VideoGame/InFamous'' is [[AttackOfThe50FootWhatever a huge]] monster in the shape of a man seemingly made of lava. The military can't stop it, it just blows them into dust and keeps walking. Cole, the Electric Man himself, can't stop it, it just gets right back up after being hit by a storm of lightning called down on it from the sky. [[spoiler: A ''nuke'' going off in its face can't stop it, it just reassembles [[ComicBook/{{Watchmen}} Doctor Manhattan-style.]] The only way to kill it for good is to kill every Conduit on the planet.]]
* Death's Hand from ''VideoGame/JadeEmpire'', who is also ''TheDragon''.
* The Sheriff in ''VideoGame/LakeviewValley'' is not about to let a little thing like a shotgun blast to the face at point-blank range stop him from bringing anyone he can prove has broken the law [[JudgeJuryAndExecutioner to justice]].
* The Creator/{{Infocom}} InteractiveFiction game ''VideoGame/LeatherGoddessesOfPhobos'' has your henchman Trent (or, depending on a choice you make early in the game, Tiffany), who continuously dies in very unlikely ways and pops up again a few dozen moves later with an even more unlikely explanation for how he/she survived.
* Definitely fitting the description on later difficulties is the Tank from ''VideoGame/Left4Dead'', which can survive magazines upon magazines of high-powered rifle and shotgun rounds and complete immolation for upwards of a minute. Combined with how hard he swings, he is NightmareFuel.
** The amount of his HP varies from 4500 to over 6000, depending on difficulty, with a wee bit over five goddamn thousand in the Versus mode. When in doubt, KillItWithFire.
** Common Infected could occasionally become ''absolutely immortal'' thanks to a bug. Using a cheat engine that displays Infected health doesn't even give comforting high numbers (like 999,999), it reveals that they simply do not exist as far as the computer is concerned. AIs will simply give up and let the Implacable Zombie kill them, and the only way to survive is to shove it into a room, close the door, and rush through the rest of the level.
** Due to a bug in damage collision, it's entirely possible to hit a zombie with a melee weapon (almost always a one-hit kill on anything not a Charger, Witch or Tank) and see it's head get taken clean off, only to have the game register it as a miss. The zombie in question is perfectly killable if you can land a second swing, but until then it will come at you bleeding and without a head.
* ''Franchise/TheLegendOfZelda'':
** ''VideoGame/TheLegendOfZeldaTwilightPrincess'':
*** The Postman. It doesn't matter where you go, what you do, or what lies between you -- he ''will'' bring you your mail! Even if you pull off the glitch of making him fall into the abyss of Hyrule Field, he'll STILL bring you your mail.
*** The two Wallmasters in the Palace of Twilight. You can stun it with your Bow and Clawshot, but you can't kill it and it will KEEP COMING FOR YOU AS LONG AS YOU HOLD ITS SOL. Although, it'll give up after you go to the "outside" area and place the Sol in the ground.
*** Then there's the Bublin King, who you have to fight four times. And in two of the fights he falls into a cliff upon defeat.
** ''VideoGame/TheLegendOfZeldaPhantomHourglass'': The Phantoms cannot even be ''stunned'' until you get the bow about halfway through the game, and cannot be defeated until you get the necessary legendary sword shortly before the end of the game.
** ''VideoGame/TheLegendOfZeldaSkywardSword'':
*** The Cursed Bokoblins are described as returning from death by way of sheer hatred and will to mess up the world. And, supposedly due to a penchant for undergarments...
*** In the Silent Realm, there's two sorts of guardians; land based and flying. The land ones are faster and carry larger weapons, but they only pursue you when you're within a certain range. The flying ones, however, will ''never stop hunting you.'' They know where you are at all times and can phase through solid objects to hunt you down. They'll just keep following you until they eventually corner you.
* The Security Officer of ''VideoGame/{{Marathon}}'' is this trope to the nth degree. Depressurization, shuttle crashes, kidnappings, literal armies on all sides, torture, being stripped of all of his weapons and dropped on a DeathWorld, insane AIs, [[spoiler:''solar systems being blown up, '' and '''the literal embodiment of chaos itself.''']] All of them have one thing in common, and it's that they couldn't even come ''close'' to stopping him.
* ''VideoGame/MassEffect2'':
** Harbinger is relentless, focused, and entirely devoted to killing ''you'', ''personally''. Since [[VillainOverride he's remotely controlling]] the Collectors, he has no problems with letting you kill his current form and possessing the next one. In his own words, '''"I WILL FIND YOU AGAIN."'''
** Then in the [[DownloadableContent DLC]], Lair of the Shadow Broker, there's Tela Vasir. She gets tackled by Shepard out of a four story window, gets in a really nasty car wreck, loses an enormous amount of blood, gets slammed in the face by a flying table yet she still provides one of the toughest (and most awesome) fights in the entire series.
** The Shadow Broker himself probably counts. He fought you for a bit, got bored, and decided to activate his own personal shield, forcing you to hit him. [[spoiler: he only dies when Liara dumps a load of plasma on his head]].
** Shepard him/herself counts given how many cybernetic enhancements and upgrades have been put into his/her body over the course of the game and his superhuman determination to defeat the Reapers. Death isn't enough stop him/her. Probably best illustrated during the ''Arrival'' DLC, when Shepard forces his/her way to consciousness through increasingly high doses of sedatives, breaks out of his/her cell without weapons, and proceeds to ''[[OneManArmy single-handedly]] [[CurbStompBattle destroy the entire facility]]'' to keep the Reapers at bay. The mooks are absolutely terrified by him/her. Lampshaded during the main game by Garrus pointing out that the Reapers killing Shepard only meant pissing him/her off.
** Zaeed Massani survived being shot in the head. At the end of his loyalty mission, an enormous beam falls on his leg, which doesn't seem to affect him. He also killed a Krogan and all his Mooks.
--> '''Zaeed''': Rage is one ''hell'' of an anesthetic.
** Garm, the Krogan in command of the Blood Pack on Omega probably qualifies as this -- Garrus remarks on how quickly he can regenerate his health. In the end, it takes Shepard, Garrus and two other members of Shepard's crew to kill him.
** Krogan in general. More pronounced in the first game where they would get back up after death unless killed by ammo that caused disintegration.
* ''VideoGame/MaxPayne'':
** Max can get plugged with hundreds of bullets in the course of the games, but doesn't seem any worse off, as long as he has a supply of painkillers to dull the pain. Lampshaded by the BigBad of the first ''VideoGame/MaxPayne1'' and again by the BigBad of ''VideoGame/MaxPayne2TheFallOfMaxPayne'':
--->[[spoiler:'''Nicole Horne:''']] (''Max Payne'') What do you mean, "he's unstoppable"? You are superior to him in every way that counts. You are better trained, better equipped, [[JustOneMan you outnumber him at least 20 to 1]]. Do... your... job!\\
[[spoiler:'''Vladimir Lem:''']] (''Max Payne 2'') What the fuck is wrong with you, Max?! [[WhyWontYouDie Why don't you just die?!]]
** In the second game, he survives being shot ''in the face''. He doesn't become mentally disabled or dysfunctional from it, either.
* All rampant in the ''VideoGame/MetalGear'' series:
** Liquid Snake from ''VideoGame/MetalGearSolid'' survives a helicopter crash, an arseload of missiles that only succeed in blowing up his HumongousMecha '''while he is inside the said mech''', a forty foot fall from the top of yet again the same HumongousMecha after being punched off it during a fistfight, and then a barrage of gunfire to the face followed by a jeep crash. He is finally killed by a [[spoiler:tailored supervirus-induced heart attack.]] And then he [[spoiler:comes back in the sequel as a talking arm. But not really.]]
** Vamp from ''VideoGame/MetalGearSolid2SonsOfLiberty'' and ''[[VideoGame/MetalGearSolid4GunsOfThePatriots 4]]''. Survives being shot in the head and heart, filled with lead and dumped in a vat of no-resistance fluid, shot in the head again, stabbed multiple times (with he himself pulling a blade stuck in his chest out through his back), and shot a few more times [[spoiler: before the AppliedPhlebotinum keeping him alive is finally deactivated.]]
** Ocelot (before he gained the nickname "Revolver") in ''VideoGame/MetalGearSolid3SnakeEater''. While not entirely murderous, he seems obsessed with besting Snake after tasting humiliating defeat early in the story. However, he is hogtied by his own sense of honor, which forbids anyone else helping him (or Snake dying at anyone else's hands [[TheOnlyOneAllowedToDefeatYou but his own]]).
** Raiden becomes this in ''VideoGame/MetalGearRisingRevengeance''. Once he learns that World Marshall is planning to create an army of child soldiers using the same training regimen that was used on Raiden, he decides to take them down. And no one, not Maverick, not enemy cyborgs, not the [[QuirkyMinibossSquad Winds of Destruction]], hell; not even [[TheDragon Sam]] could stop him in their rematch. Oh, and Raiden can now slice open his foes and steal their nanotech to heal himself completely, making him even more difficult to stop.
** ''VideoGame/MetalGearSolidVThePhantomPain'' has The Man On Fire, a wraith WreathedInFlames with an EnergyAbsorption ability that can take '''any''' physical force you throw at him and send it back at you ten-fold. This can be anything from a sock to the face or small arms fire to taking an ''RPG-7, Sidewinder Missiles, and a goddamn '''tank shell''' to the face'', and being barely more than fazed before he unleashes death upon whoever tried to fight him conventionally. [[spoiler: His death didn't even come by conventional means, but after he realized that Venom Snake was not the person [[PowerOfHate fueling his rage]], and he basically ''shut himself down''.]]
* ''VideoGame/MetalSlug'':
** Humorously done by [[TheDragon Allen O'Neil]]. In the second game, he gets eaten by a killer whale upon defeat and ''still'' comes back for the sequels. When asked about his immortality, the game staff responded that the reason he never dies is because he both "has a body of steel and guts", and he has a wife and son to return to at the end of the day (a strange inversion of FatalFamilyPhoto there).
** When one of your OneHitPointWonder characters comes back from the dead -- either through using an extra life or using a continue -- all enemy soldiers on-screen briefly ''freak out'' over their inexplicable resurrection.
* ''Franchise/{{Metroid}}'':
** The SA-X in ''VideoGame/MetroidFusion''. Somewhat more complicated in that it's a copy of the heroine, with all the Metroid-killing equipment she wielded at the end of the last adventure. The real heroine starts off pitifully unpowered by comparison, and ''is now part Metroid'' to boot. Talk about stacking the odds against you. At first you can't do anything against it and just have to run away, but later on you can freeze it to slow it down.
** Samus herself is also an example. This is especially clear in the ''Prime'' series where you can read Space Pirate logs that speak of "The Hunter" as an unstoppable killer capable of obliterating their entire armies singlehandedly.
** The [[LifeDrinker Metroids]] themselves, unless you're packing a [[KillItWithIce cryo-based weapon.]]
** Dark Samus, a near unkillable doppelganger of Samus who thrives on Phazon and can come back FromASingleCell. Best displayed after beating her near the end of ''VideoGame/MetroidPrime2Echoes'', where she uses the last strength she has left to crawl towards Samus and attempt to grab her for one last attack before collapsing, eerily similar to [[Franchise/{{Terminator}} another Implacable Man]]. Then she returns in ''VideoGame/MetroidPrime3Corruption'', and [[HeroKiller is more dangerous]] [[TheChessmaster than ever.]]
* In ''VideoGame/{{Minecraft}}'' as long as healing crystals are intact, the Ender Dragon is unstoppable. If placed in overworld, it can fly right though anything that's not Obsidian, End Stone or Bedrock. Still feel secure in your cobblestone home?
* ''VideoGame/NetHack'' has the Wizard of Yendor. He's certainly killable, but that doesn't stop him from coming back to torment you all the way through the Elemental Planes, steal the [[MacGuffin Amulet of Yendor]] and create copies of himself to help with this.
* ''VideoGame/NeverDead'': The protagonist. Dismember him, run him over, or pierce him through. He [[ExactlyWhatItSaysOnTheTin never dies]].
* The Blood Hound is an enemy from ''VideoGame/ThePersistence'' who wanders from room to room on a deck hunting you down. It has by far the most health of any enemy and doesn't flinch upon being hit or shot in the head.
* ''VideoGame/Persona3'': [[TheGrimReaper The Reaper]], also known as "Death." It exhibits the "slow walk" by showing up whenever you take too long to advance to the next area. Even your support character warns you that you "can't defeat it!!", and tells you to get out immediately. It can be defeated it very high levels, but even if you do, it will still come back for more.
* ''VideoGame/Pikmin2'': The Waterwraith, is invincible unless you have purple Pikmin at your disposal. Unfortunately for you, you don't have any purple Pikmin when you enter the cave he dwells, and won't get access until you've reached the final floor.
* ''VideoGame/PlanescapeTorment'':
** The Nameless One, unless he wishes himself out of existence or screws up when meeting the BigBad.
** [[KnightTemplar Vhailor]] plays this trope as straight as can be. He is basically an avatar of Justice who will stop at nothing carry it out. He grows more powerful when hunting those who've committed greater crimes. [[spoiler:During your confrontation with [[BigBad The Transcendent One]], you can inform Vhailor about who you and The Transcendent One are, which transforms him into a [[WarGod God of War]]]].
* ''Franchise/{{Pokemon}}'': Primeape will beat the ever-loving shit out of [[HairTriggerTemper anything that pisses it off]], even if it has to chase it to the end of the world. But what ''really'' pushes it into this territory is the fact that, as of ''VideoGame/PokemonScarletAndViolet'', even death does not stop its rampage; it simply evolves into Annihilape instead, gaining the Ghost-type in the process.
* The Dahaka from ''VideoGame/PrinceOfPersiaWarriorWithin''. Subverted in that [[KillItWithWater it can be killed]], but there is only one weapon in the game that can actually do that and getting it is less than easy.
* In ''[[VideoGame/WingCommander Privateer]]'', later in the game when you find and equip the [[ImportedAlienPhlebotinum discovered Steltek gun]] on your ship, a Steltek drone will appear at random and attack only you. Your weapons won't scratch it, and although you may give it the slip using jump points, it will eventually show up again. You only finally get the ability to kill the drone just before the final mission [[spoiler:when an actual Steltek comes along and charges up the mounted Steltek gun to give it the ability to harm the drone]].
* ''VideoGame/{{Prototype}}'': Alex Mercer, and he's on a RoaringRampageOfRevenge all across Manhattan. He survives [[spoiler:being torn to pieces in the blastwave of a ''nuke'', regenerates FromASingleCell by absorbing nothing but a ''crow'', and states that his work is ''almost'' done. Not done. ''Almost'' done]]. Imagine being the guys assigned to take him down. Over the course of the game, he murders his way through what has to be three-quarters of [[SemperFi the marine forces]] -- by way of kicking their helicopters out of the sky, tearing their tanks to shreds with his bare hands, and ripping apart ''entire bases'' -- and comes out no worse for the wear. He ''is'' the Implacable Man. And he makes sure they ''know it''.
-->'''Alex:''' '''''NOTHING CAN PROTECT YOU FROM ME! NOT MEN! NOT WEAPONS! NOT ARMOR!'''''
* In the MMO ''VideoGame/RagnarokOnline'', the Monk character class gets access to the skill "Steel Body", or "Mental Strength" in one translation, that cuts all damage, magical or physical, to 1/10 if you have no vitality or intelligence, and if those two stats are high, any attack will do ONE damage! Another class (the tank furthermore) has a skill that does big damage in an area, but returns some to its caster. But a glitch can be exploited to make it HEAL you instead, thus doing huge damage to your foes while filling your own life gauge back up. In either case you get a nearly unstoppable character.
* ''VideoGame/Rayman3HoodlumHavoc'' has a level full of these called The Desert Of The Knaaren. The Knaaren are virtually indestructible, not even flinching from any attacks, and will chase you on sight. Word of advice: RUN.
* ''Franchise/ResidentEvil'':
** Lisa Trevor in ''VideoGame/ResidentEvilRemake'', though [[spoiler:thankfully she's not after you specifically but [[TearJerker just wants her mother]] -- she'll chase you when you enter her cabin or her territory in the caves, and she'll attack you when you're too close to the crypt where her mother's remains are, but if you leave the area she lets you go and if you open the crypt for her she morosely takes her mother's skull and retreats by hurling herself off the ledge never to be seen again by Jill or Chris]]. She shows up again, no worse for wear, in ''[[VideoGame/ResidentEvilTheUmbrellaChronicles The Umbrella Chronicles]]'' to chase Wesker, though this time is ''far'' more determined to hunt him down and kill him as she [[ItCanThink apparently recognizes him]] as [[ItsPersonal one of the men responsible for ruining her life and killing her mom]].
** Tyrants (games ''[[VideoGame/ResidentEvil0 0]]'', ''[[VideoGame/ResidentEvil1 1]]'', ''[[VideoGame/ResidentEvil2 2]]'' and ''[[VideoGame/ResidentEvilCodeVeronica Code: Veronica]]'') also count. You will always have to fight a Tyrant ''at least'' twice, and with the exception of the Proto-Tyrant in ''VideoGame/ResidentEvil0'', killing one ''always'' requires the use of [[StuffBlowingUp high explosives]]. Guns, grenades and ''immersion in molten metal'' will not be enough to kill one. Given that Tyrants are meant to be {{Super Soldier}}s, this is to be expected.
** The Tyrant T-103, encountered in [[NewGamePlus Scenario B]] of ''VideoGame/ResidentEvil2'', deserves special mention. He wants [[spoiler:Sherry's locket, which contains a sample of the G Virus]], and absolutely nothing will stop him from getting it. Towards the end Leon/Claire drops him into a smelting pit, and it ''[[TurnsRed only pisses him off]]''.
*** He's even worse in the [[VideoGame/ResidentEvil2Remake remake]], where instead of scripted events where he appears, he's always somewhere in the police station looking for you[[note]]There are still a few scripted events where he finds you no matter what, and it's rumored you can encounter two at once by happening to encounter the roaming Mr. X in the same area where a scripted encounter takes place[[/note]]. ''Always''. Shoot a gun nearby and he'll come running to investigate so you'd better keep moving. Worse still, pumping him full of bullets will only drop him to a knee stunned, giving you maybe half a minute at most to run away before he gets back up and resumes hunting. It takes a lot of bullets too, and they [[ImmuneToFlinching barely even stagger him]], so your best bet is to just run your fool ass off and hope you can ditch him. In short, he's become less of an Implacable Man and more TheJuggernaut.
** The Nemesis from ''VideoGame/ResidentEvil3Nemesis''. He's the only enemy in the game that can follow you from room to room ''and'' outrun you. It takes at least ''14 shotgun shells'' to kill him on ''EASY MODE''. No, wait, it gets better. [[spoiler:That doesn't actually kill it. You just knock it out. Nemmy'll show up later. Throughout the course of the game, he gets repeatedly shot, blasted out of a train with a grenade, has a rocket launcher blow up in his face, passes out into burning helicopter wreckage, soaked with acid, and by the end, he's been decapitated, falls into a pit of acid designed to break down [=BOWs=], and ''still doesn't stop''.]] Even worse, is this time he's after '''Jill''', not lashing out at all life, not trying to retrieve a locket, not "cleaning up" by killing generic cops or survivors, he wants the S.T.A.R.S. members specifically and he introduces himself by killing Brad, leaving you as the last and only one on his hit list. [[spoiler:During the boss battle against him as Carlos, he's more than content to walk right past the mercenary and into the room where the incapacitated Jill is unless you press your attack enough to [[RageBreakingPoint keep him focused on you]].]]
*** On top of that, in the ending [[spoiler:you must hit it with two shots from a railgun the size of a train car; and after that, you get the option to put six bullets right in its head. That finally kills it]].
** ''VideoGame/ResidentEvil4'' subverts this with the Regenerators. From the first meeting it seems that nothing can stop them... Unless you're ''really'' lucky with blind firing or high-end explosives, as it's later revealed that they simply have [[AttackItsWeakPoint hidden weak points]] that can be revealed with a special weapon. Bad guys like Mendez and Saddler, however, still play the trope straight, with Saddler [[spoiler: [[ImmuneToBullets ejecting the bullets from his body through his hands]]]]. And then there's [[ThatOneBoss El Verdugo]], though it is possible to finish the game without killing this guy, which is probably what most players do their first few times around. The Verdugo is ''so'' hard to kill, that some players are left with the impression that he's a HopelessBossFight and that he simply ''can't'' be killed, only escaped. He's more vulnerable under the effects of liquid nitrogen but it still takes a ton of firepower to take him down.
** [[BigBad Albert Wesker]] himself. He survived being slashed/impaled by Tyrant due to his regenerative PsychoSerum, and having a load of girders dropped on him, and can dodge bullets and catch rockets ''Matrix'' style. [[spoiler:Until he [[BodyHorror mutates]] into a OneWingedAngel form at the end of ''RE 5''.]] Even then he can survive the heat of lava, and takes a barrage of rockets to the heart before dying for good. [[spoiler:He plunged his hand into the container, laughing maniacally as the Uroboros swarmed up his arm.]]
** ''VideoGame/ResidentEvil6'' has Ustanak, the monster whose only goals are to brutally murder Jake and Sherry and try to outdo Nemesis for the coveted title of "Most Unstoppable Killing Machine". Even getting a DRILLING MACHINE THROUGH THE CHEST only takes him down for about 5 literal minutes. It also has the Rasklapanje, an {{expy}} of the Regenerator, who are fought in all the four campaigns. In a cutscene, Leon and Helena kill one only to watch it pull itself back together effortlessly. While it seems they can be killed by separating their body parts and killing each part individually, after sometime the parts revive and the creature reassembles itself. However, most of the times you meet them are in areas where they spawn infinitely, which makes going through the trouble of killing them a pointless endeavor.
** ''VideoGame/ResidentEvil7Biohazard'': Jack Baker, the patriarch of the [[CannibalClan psychotic]] and [[HealingFactor nigh-indestructible]] Baker family. Part one of the game involves you trying to find a way out of the house while he wanders around, chasing you if he sees you, and any attempt at fighting him will annoy him and waste your resources. It's only when you defeat him in an epic chainsaw duel that you put him down...[[spoiler: only for him to come back as a completely mutated mold creature for one more go at you. He seemingly dies for good after being calcified by a serum. In the DLC Chapter ''End of Zoe'', TheReveal is that the Swamp Man is none other than Jack. A document in this chapter explains that Jack's unique genetic makeup allowed his Mold mutation to give him a more potent Healing Factor, more so than any of the other members of the Baker family. Calcification is the nail on the coffin for those infected with the Mold, but he was able to survive and mutate again! Later on in ''End of Zoe'', his brother [[TheProtagonist Joe]] ''decapitates him'', but he reattaches his head off-screen and makes a comeback. Nothing short of a MegatonPunch from Joe with the [[PowerFist AMG-78]] to Jack's head actually kills him, causing it to ''[[YourHeadASplode explode]]'' and calcifying his remains.]] His wife Marguerite acts much the same way, but she usually relies on her insects to protect her and overwhelm her prey, and she's not nearly as stubborn as her husband.
** ''VideoGame/ResidentEvilVillage'' has [[OurVampiresAreDifferent Alcina Dimitrescu]] to fill this role. After a couple of scripted encounters, Lady Dimitrescu freely roams the castle just like the Tyrant in [=RE2=] remake and Jack Baker in ''[=RE7=]''. Unlike them though, her regenerative abilities are so strong that you can't even take her down temporarily; she just shrugs off any and all attacks (even from New Game+ weapons) without even blinking. [[spoiler:The only way she can be defeated is by stabbing her with a [[PoisonedWeapons poison dagger]] created specifically to kill her, and even then she keeps herself alive by mutating into her OneWingedAngel form for one last fight.]]
* The Ballistikraft robots from ''VideoGame/RiseOfTheTriad''. Invincible, hulking robots that roll towards you very slowly, shrugging off anything and everything you fire at it and spewing rockets at you. The only thing you can do is run.
* ''VideoGame/RuneScape'' had a couple of these guys that you saw that is implacable in general:
** First one is Lucien in While Guthix Sleeps, an evil [[ProudWarriorRaceGuy Mahjarrat]], during a cutscene where a series of heroes go and [[spoiler:try to]] fight the guy.[[spoiler:Needless to say, most of them [[HeroKiller bite the dust for good]] and [[KilledOffForReal they DO NOT come back]].]]
** Second Nomination will be the Corporeal beast, a result of NiceJobBreakingItHero. It comes to the corporeal realm to deliver a can of whoop ass for anyone willing to take a one way trip back to Lumbridge. Before it came to the corporeal realm, it was ''merely'' [[SealedEvilInACan trapped]] in the [[SpiritWorld Spirit Realm]], siphoning energy off the souls of a dead family for two quests. [[spoiler:And then you show up. Naturally, living soul energy is much more potent than dead soul energy...]]
** The final nomination will be [[OurVampiresAreDifferent Vampyres and Vyrewatch]], monsters that can't be beaten with even a [[InfinityPlusOneSword Godsword]], instead until you have a silver weapon, good luck fighting these guys. Even then, merely silver weapons will only work on Juvinates, the weakest form of the species; anything higher than that has limited mind reading and impossibly good reflexes, meaning any weapon with a predictable pattern (that is, all of them except a flail) can't even hit them to begin with.
** On the flip side, there's you, the player character. While quests generally act as if you don't die and do entire sections in one trip rather than individually (such as the finale of Dragon Slayer 2), you're known to be a warrior on par with the Wise Old Man and Robert the Strong, able to slay a Dragonkin's finest creation, which is so strong it can take out a Dragonkin itself in one blow[[note]]Robert the Strong is famous for being capable of killing Dragonkin ''at all''[[/note]] and a corrupted fragment of a god, capable of getting around any obstructions regardless of what they are, and being one of the few characters capable of canonically surviving dying.
* The Death spell in ''VideoGame/{{Sacrifice}}'' summons TheGrimReaper temporarily, who is treated by the game engine as a spell effect and not a creature; he cannot be targeted, shielded against, blocked, halted or damaged in any way, and will not stop hunting his target until he has killed it. If Death targets one of your creatures and you teleport away with it to the other end of the map, Death will immediately realign his course and slowly start following, ignoring everything else in his path.
* Both in and out of gameplay in the ''VideoGame/SaintsRow'' series, assuming you do enough diversions. Blowing up The Boss just gets them pissed off, and in the second game, the full complement of perks means that The Boss can jump out of a plane, get hit by three exploding trucks [[IncendiaryExponent on fire]], and take a point-blank shotgun blast to the face without going down. ''VideoGame/SaintsRowTheThird'' turns this [[ExaggeratedTrope Up to Eleven]] once you get close to max respect, with several upgrades making them immune to each type of damage. It can get to the point where The Boss can only be harmed by melee attackers.
* ''VideoGame/ScarfaceTheWorldIsYours'':
** Tony can enter a [[SuperMode Blind Rage]], where he exhibits true Implacability. He becomes immune to attacks, doesn't flinch, gains auto-aiming and the quasi-vampiric ability to heal by attacking enemies. Although it lasts for only brief periods, it can be reused and the meter needed to fuel it can be filled up fairly quickly. For that matter, Tony in general; he's gonna take Miami back and kill Sosa, and heaven help the [[ForeignCussWord chazzers]] stupid enough to get in his way.
** BigBad Alejandro Sosa exhibits apparent-Implacability the way Tony did at the end of the film, taking whole clips to the chest without flinching. Even from the mighty [[HandCannon Desert Eagle]] that instant-kills everyone else. [[BoomHeadshot A good few headshots]] are needed to end him.
* As [[DigitalPiracyIsEvil an anti-piracy]] measure, ''VideoGame/SeriousSam 2'' will [[DevelopersForesight set one of these loose on you if it detects a pirated copy of the game]]: An indestructible [[LightningBruiser lightning-fast]] giant-scorpion creature will follow you from practically the start of the game. It can't be killed and it's too fast to escape from for long. Of course, this merely [[DoNotDoThisCoolThing spawned a sub-set of players who seek out pirate copies just to see how long they could last against the beast]].
* Fox Face from ''VideoGame/ShadowHearts1''. If your Malice meter is filled, he ''will'' appear and hunt you down. You can beat him, but he will come back again and again, until you either clear the Malice or die.
* Most of the colossi in ''VideoGame/ShadowOfTheColossus'' qualify for this, with the only exceptions being Avion and Phalanx. Once the others have spotted Wander, they will not stop trying to attack him until he becomes physically inaccessible, dies, or kills them. Particularly notable is Dirge, which is reputed as being unique in that it is the only Colossus who seems to genuinely hunt Wander in order to devour him rather than just try to kill him. In fact, the reason Dirge's [[GlowingEyesOfDoom unnervingly large eyes]] are always [[RedEyesTakeWarning orange]] is because it is one of the few colossi who is ''constantly'' attacking.
* ''Franchise/SilentHill'':
** ''VideoGame/SilentHill2'' has the Pyramid Head: Usually the only way to survive an encounter with him is to run your damn fool ass off, and hope he doesn't catch you. The game suggests the Pyramid Head is merely a gatekeeper whose purpose is to herd you in the right direction. He is never truly defeated; he merely strolls away menacingly or kills himself once his purpose is fulfilled. In that sense, he is closer to a Juggernaut.
** Walter Sullivan from ''VideoGame/SilentHill4'', at least until the boss battle when his defenses are finally lowered. The Ghost Victims of the game also apply, since they will keep chasing Henry from level to level unless pinned down by a (very rare) sword.
* Officer Carmelita Fox from ''VideoGame/SlyCooper''. Wherever Sly is, Carmelita soon follows in hot pursuit.
* In ''VideoGame/SonicAdventure'', Dr. Eggman's robot ZERO chases Amy in every level for the bird with her, and whenever Amy loses ZERO, he soon catches up. [[spoiler:His tenacity even after his target has been obtained and is no longer of use to Eggman gets him killed.]]
* Played with in ''VideoGame/SouthOfReal''. Yes, the shadows are chasing [[PlayerCharacter Alex,]] but all they want is a lovely little family reunion. You happen to be still alive, but don't worry--they can fix that.
* ''VideoGame/StarCraftI'': The Torrasque is a special, one-of-a-kind super-Ultralisk that just gets reincarnated back at the base when it's killed, over and over and over again. It makes a return in ''VideoGame/StarCraftIIHeartOfTheSwarm'' as a possible mutation for all of Kerrigan's Ultralisks: the ability to revive once upon death.
* ''Franchise/StarWars'':
** ''VideoGame/JediKnightJediAcademy'' has four levels that involve different variations of the theme of an enemy (or several) chasing you that can't simply be killed, and three of the enemies fit this trope.
*** The sandworm will eat you in one bite if you stay on the sand long enough.
*** The rancor. If you actually want to kill it, it's harder than many boss battles... and when you do kill it, another one replaces it. So you'll end up avoiding it anyway. Its powers of following you are less impressive, as it gets lost and can't fit under doors.
*** Boba Fett. He's opposed to the idea of your finishing your mission, so he'll pit his BadassNormal powers against your Jedi ones at every turn, only to fly away if you manage to damage him enough and return soon after returning to full strength.
*** And finally, the mutated rancor. It's practically Godzilla, and it's completely immune to damage, so it's actually TheJuggernaut as well. Breathing poisonous gas and flailing at things, it will follow you all over the complex in the level, its steps making the floor quake, and demolish the scenery and [[HoistByHisOwnPetard eat the badguys who released it]] when it can't find you. When you find a way to sneak into the next hall through an exit it can't fit through, it will bang the wall until it yields and resume pursuit. [[spoiler: At the end, you'll be able to kill it by crushing it on a conveyor belt between a giant crate and an energy field that only lets giant crates through.]]
----> '''Jaden Korr:''' What did I ever do to ''him''?
** In ''VideoGame/KnightsOfTheOldRepublic'', Darth Malak sets the entire Star Forge against the protagonist, sacrificing thousands of his own men with the sole intention that it might potentially ''slow'' them down. Part of the reason such [[ThereIsNoKillLikeOverkill overkill]] is justified is because he's facing [[spoiler: an amnesiac Darth Revan, his former Master]]. Darth Sion from [[VideoGame/KnightsOfTheOldRepublicIITheSithLords the sequel]], who you can only kill by [[spoiler: [[WarriorTherapist convincing]] him that his life isn't worth living]]. According to the KOTOR Campaign Guide, Sion was once a living man, filled with so much hatred that when he finally was killed, his hatred and strength in the dark side allowed him to keep living, AND kill his assailant RIGHT THERE ON THE SPOT. He is bound together purely by his hatred. Oh, also, according to the medical records aboard the ''Harbinger'', his flesh has been cut into a bunch of rotting chunks that now make up his body, and and each of his bones has been absolutely splintered and pieced back together.
* ''VideoGame/StreetsOfRogue'': The Killer Robot Disaster has HP in the ''thousands'', and will slowly march towards your character while shooting an unlimited supply of rocket-propelled grenades. It cannot be hacked, possessed, or bribed to leave, but it is susceptible to water -- barely. Most players just try to get their chores done so they can leave the floor as soon as possible.
* ''VideoGame/StringTyrant'': Has The Stranger, an ominous trenchcoated figure that will continually search for Mary. It respawns about 20 turns after defeat stronger than ever. [[spoiler: It's finally defeated by using a church's bell to shake it to pieces.]]
* The Inspector and his dog in ''VideoGame/SubwaySurfers'': No matter how fast or far you're running, no matter how big a lead you get, thanks to a jetpack or mega-headstart powerup -- one stumble and The Inspector will appear right on your heels.
* Luca Blight from ''VideoGame/SuikodenII''. Just look at [[NoOneCouldSurviveThat what it takes to finally kill him]]; it includes several battles against several elite warrior squadrons (plural) whaling on him, enough arrows stuck in him to build several houses with and one final duel with the opposite army's champion, and even then he goes down laughing because it took ''that'' much.
* ''Franchise/SuperMarioBros'':
** In ''VideoGame/SuperMarioBros2'', there's Phantos, the creepy EvilMask that guards keys. If you take a key its guarding, it comes to life and chases you non-stop. It can't be killed (unless you grab a Starman) and the only way to shake it is to drop the key, although this is a temporary solution, because picking the key up again (and you'll always need it) causes the thing to resume the chase until you reach the key's door.
** [[TheUndead Dry Bones]] take as many jumps as you can dish out and still come back for more, that is unless [[spoiler: you had [[GameBreaker an invincibility star or a cape]] from ''VideoGame/SuperMarioWorld'']]. In ''VideoGame/SuperMarioRPG'', however, jumps are considered magical attacks, which Dry Bones are very weak to. As such, they can be felled quite easily with a single jump, whereas physical attacks such as Mario's punches, hammers and shells cannot do shit to them. It's ''still'' only enough to take them down only temporarily: about 10 seconds after the fight and they'll get right back up and come after you again.
** In ''VideoGame/PaperMario'', Jr. Troopa takes everything you can dish out and comes back for more time and time again. If you use Goombario's tattle ability, he'll keep getting more impressed with Troopa's tenacity each time. Tubba Blubba is completely unstoppable until you find his heart and make him mortal again. Mario and co. are aware of this, and immediately run for their lives in a chase sequence when he catches you in his castle. Attempting to attack him at this point is an unwinnable battle.
** ''VideoGame/SuperMarioBros3'': Chain Chomps don't like Mario standing there staring at them; they'll keep launching themselves at him over and over. After the 46th launch, the chain starts flashing to show it's weakening... And the 50th launch will '''[[OhCrap snap the chain]]'''. The now-free Chomp will pursue you quite fast, taking huge leaps where necessary to catch up and bite you, its tormentor. ''VideoGame/SuperMarioGalaxy2'''s Chomps cannot be stopped except by an invincibility star.
* David Leatherhoff of ''VideoGame/SvenCoop''. Admin-controlled, he's on the players' team so friendly-fire is impossible (against him, that is). David is by no means "friendly" and will relentlessly stalk and harass the players no matter what.
* ''VideoGame/TeamFortress2'':
** The mod "Freak Fortress" pits the entire team against one of these, which can vary from [[BadassNormal psychotic offshoots of the main characters]] to [[HumanoidAbomination full-blown monstrosities]], but will always be ''[[DamageSpongeBoss really]]'' tough, and strong enough to one-shot almost anything.
** In Mann vs. Machine mode, some of the harder rounds feature a [[GiantMook Super-Huge]], [[KingMook Super-Strong]], Super Unstoppable Robot--they can only be knocked back by the Heavy's Rage powerup, and (excepting Giant Scouts) will simply ''walk over'' any obstacles that they can't immediately destroy.
** Furthermore, a Medic with the stock Medigun can make himself and his current healing target Implacable Men (or Implacable Man and [[AmbiguousGender Pyro]]) for several seconds at a time, thanks to his Ubercharge ability (though they can still be bounced around by airblasts and bombs). [[TheBigGuy Heavy]] says it best.
--->'''Heavy, being Ubercharged:''' Is good time to run, cowards!
** Parodied by the Soldier with one of the lines he speaks while wearing his [[PaperThinDisguise cardboard robot costume]]: in an [[LiteralMinded overly-literal]] reinterpretation of the page quote, he claims: "I will find you! That's what I do! That's '''all''' I do! THERE YOU ARE! ... ''Shutting down''..."
* ''VisualNovel/{{Tsukihime}}'' has a few of these as well.[[spoiler:From Arcueid being cut into 17 pieces and coming back to life the next day, Roa being taken down to nothing but his ankles and immediately regenerating, and Nero having his body ripped in two only to make fun of the person who did it. They have this trope covered.]]
* [[spoiler: The PlayerCharacter in]] ''VideoGame/{{Undertale}}'' [[spoiler:''canonically'' has the ability to load their save file upon death through [[{{Determinator}} Determination]], meaning that killing them will only slow them down until they learn your patterns and breeze past you without you even touching them. They especially resemble this trope in the genocide route, where they will [[LevelGrinding walk around in circles and kill anyone unlucky enough to cross their path]] and only move on once the area is devoid of life. On top of their effective immortality, they become so powerful later on that they OneHitKill would-be [[BossBattle bosses]] with [[ThereIsNoKillLikeOverkill millions of damage]]. What most players consider to be the hardest boss in the game, [[BewareTheSillyOnes Sans]], knows that it's impossible to actually beat you, and instead attempts to wear you down mentally by killing you repeatedly and guilt-tripping you so that you eventually give up. As his final "attack", he simply doesn't take his turn, thus trapping the both of you there for all eternity until you get bored and quit. But even the ''RULES OF THE GAME'' aren't enough to stop you, as you push the bullet box over to the fight button and strike Sans twice in a row, finally landing a hit and one-shotting him.]]
* Selvaria in ''VideoGame/ValkyriaChronicles'' is this when her Valkyrian powers are activated. No attacks you fired at her did any damage. When she showed up, your only option was to make your units take cover and hurry to finish the objective. Even when she isn't a Valkyria, she's still pretty powerful.
* After it is released in the third section of ''VideoGame/VivisectorBeastWithin'', the Overbrute Panther becomes an Implacable Man; while you can blast whole chunks out of it, it won't be slowed one iota by it, and will instantly regenerate, and unless you find some way of locking it out temporarily, it will ''always'' catch up with you and kill you with a casually-placed detonator to the chest. Oh, and it can turn invisible at will, as well, to both sight and radar, making it even harder to avoid the monster. Games designers are sadists, clearly.
* ''VideoGame/{{Warframe}}'' features the Stalker, a creepy-looking warrior in black carrying a decent scythe and one of the best bows of the game. He marks you for death everytime you kill a boss (killing more bosses, even for farming purposes, just adds more marks) and has a random chance to appear during almost any mission. He'll make himself known by flickering lights and taunting you over your comms, then lock you in your current room before teleporting inside. Either you kill him, either he kills you. No other alternative. And he can walk his talk, being able to tear apart players who aren't carrying high-quality gear. Think the mooks or your allies will stop him? He will just ignore or (if attacked) kill everything in the room if it means getting to you. And after [[spoiler: you do the Second Dream quest]], he turns into the even stronger Shadow Stalker.
* Wario in ''VideoGame/WarioLand'', where he has infinite health. The main gimmick is that he ''has'' to hurt himself with the various obstacles and enemies in order to solve puzzles.
* You as Rubi in ''VideoGame/{{Wet}}'', you will regularly tear through rooms stacked to the brim with {{Mooks}} and survive. A more pure example is the ending, [[spoiler: where Pelham sicks his pet Albino Tarantula on you. After you kill her, you come after Pelham and he tries shooting you, it doesn't work and you behead him]].
* ''VideoGame/{{Wick}}'' features a family a murderous ghost children that pursue the player relentlessly, but special mention goes to Caleb. Once he spawns on the map he slowly, but surely digs towards the player until the hour is up.
* Asgard in ''VideoGame/WildArms3''. Guns and spells? Barely fazes him. A structure collapses on him? Minor inconvenience. Sending him to the distant past? [[TheSlowPath Ha ha, yeah right]]. The only reason you even manage to kill him [[spoiler: [[SuicideByCop was because he allowed you to kill him]] [[ICannotSelfTerminate so he can follow his masters to hell]]]].
* ''VideoGame/WorldOfHorror'' has the being known only as Something Truly Evil. If you're unfortunate enough to attract its attention, it starts popping up in other random encounters, relentlessly stalking your character until it finally attacks. When it does, you're [[HoplelessBossFight unable to harm it or run away]], and your only options are to sacrifice your Health and Reason until you either perish, go mad, or manage to appease Something Truly Evil and it lets you go.
* While Death Knights in ''VideoGame/WorldOfWarcraft'' are [[MightyGlacier not very fast]], they are hard to slow down: Wraith Walk resists snares, Icebound Fortitude cancels most stuns, Pillar of Frost [[NoSell No-Sells]] knockbacks, and [[AntiMagic Anti-Magic]] Shell is a Swiss army knife for ignoring control effects.
* The Lobstermen of ''VideoGame/XComTerrorFromTheDeep'', like their predecessors the Chrysalids, will give this impression when you first encounter one. You fill it with harpoons, your squad opens fire with Gauss pistols, you launch torpedoes at it... and you watch in horror as it somehow survives it all and proceeds to mow down your troops.
* ''VideoGame/{{Xenogears}}'' has Ramsus. The guy's been blown up, had his HumongousMecha thrashed repeatedly, and nearly drowned. Yet all of that doesn't stop him from trying to fight his rival [[LetsPlay/TheDarkId FEEEEEEEIIIIIIIIIIIIII!!!!]]
** Id. If he has to "step in" to handle [[spoiler: Fei]]'s problems... everything in sight is going to be very dead very soon. Including ''an entire continent'' except for one person, a small village, a fortress city of TheEmpire, entire fully armored batallions...
* ''VideoGame/Yakuza0'': Yoneda, Kuze's NumberTwo, becomes a recurring enemy throughout Kiryu's rampage through Dojima HQ at the start of the game. No matter how many times Kiryu knocks him flat on his ass or uses him to [[OpenSaysMe unlock doors]], [[MadeOfIron Yoneda will get back on his feet within minutes]] and attempt to ambush Kiryu while he's distracted. It takes Kiryu smashing his face against a urinal and [[DivingKick dropkicking]] him [[DestinationDefenestration off a fifth story window]] before Yoneda stays down for a meaningful amount of time.
----
* The Queen of Hearts' Executioner in ''VideoGame/AliceMadnessReturns'' is a giant, undead card guard wielding a scythe who will relentlessly pursue Alice once she enters the castle. At most, her weapons -- from the [[ImprobableWeaponUser acid-lobbing teapot]] to the [[MoreDakka pepper-grinder gun]] only make him stumble. [[spoiler: A bite of familiar cake brings the whole chase to a very satisfying end.]]
* The Alien in ''VideoGame/AlienIsolation'' is almost completely invincible to everything that the player has. It is incredibly fast (much faster than [[PlayerCharacter Amanda]]), and if it grabs Amanda then it's [[OneHitKill game over]]. The only options are to avoid it as best as possible and, later in the game, drive it off temporarily with a flamethrower. Of course, even with the flamethrower, [[ArtificialBrilliance it learns to adapt if over-relied on]].
* ''VideoGame/AmnesiaTheDarkDescent'' has a collection of {{Humanoid Abomination}}s that serve only to pursue and murder the player. So you've blocked the monster's only entrance with about fifteen crates and plenty of furniture? '''''[[https://www.youtube.com/watch?v=VkWr_CBSxGI&t=180s Good luck with that.]]'''''
* ''VideoGame/{{Arknights}}'': Executor Federico of the Laterano Notarial Hall is depicted as this, befitting his TerminatorImpersonator image.
** His resume lampshades this.
--->''[[BeCarefulWhatYouWishFor Be careful what you wish for]], because he really can accomplish things that border on absurdity or impossibility.''
** In the chapter ''Survival Notorization'' of the event Operational Intelligence, he is seen pursuing the young huntress Vermeil through her homestead in Siracusa, disarming booby traps and catching arrows coming his way without much trouble. At the end of the event he offered to help her fight off the Ursus mercenaries coming for her, and since both of them made it to Rhodes Island as operators it's safe to assume he killed them all.
** His profile states that executors like him are only deployed on the most challenging of missions. His work records included: killing 41 hardened criminals to deliver an item, damaged six buildings to shutter a company, killing a chief executive of a city state guard unit over a money dispute, and almost caused a war when fulfilling the wishes of the contracted citizens.
--->''Most of Executor's mission record is like this. It is clear that the Notarial Hall deploys its executors only to the most challenging of missions.''
* ''Franchise/AssassinsCreed'': Altaïr is a mortal man. Altaïr is [[BlatantLies apparently susceptible to regular weapons]] such as swords, arrows, daggers, and [[ArsonMurderAndJaywalking small thrown rocks]]. Altaïr will slaughter his way through an ''ambush'' of roughly fifty EliteMooks in about fifteen to twenty minutes without bothering to rest afterwards because he has sworn to [[NeverSayDie remove you from this mortal coil in a timely fashion]], and anything that gets in his way is just one more thing to cut down. There is a reason he is a MemeticBadass, and there is a point where a "normal person" just can't be defined as a {{Determinator}} anymore. For Altaïr, that point is probably about when he mercilessly cuts fifty-plus men into chunks (or runs them through, if he wants to spice things up), including the archers who are ''shooting him as he fights''. Then, just to make completely certain that you know he's an Implacable Man, he goes straight from the trail of bodies to TheDragon, stopping only to accuse the man of treason and kill ''another'' twenty Elite Mooks before finally taking on TheDragon one-on-one and administering a fatal CurbStompBattle. Yes, that's right. Altaïr [[CurbStompBattle Curb Stomps]] ''TheDragon'' after having spent probably the last half-hour fighting off over ''seventy soldiers''. If you see [[http://i34.tinypic.com/bedhmq.jpg this man]] heading in your direction, DontAskJustRun.\\\
Whether he's aiming for you or not, it generally seems like a good idea to flee from a man [[FightMagnet whose very existence]] tends to incite bloody battles to the death that often rage across multiple streets in a frenzy of blades and blood. You might not be his target, but you should probably get out of his path. You should start running if you see Altaïr, but...[[ParanoiaFuel chances are you won't see him]] until he rams a metal spike into your neck.
** The same goes for Ezio from the sequel. The man fights his way into the Vatican, merrily slaughtering the Pope's [[EliteMooks personal guard]] as he goes. He then shrugs off a blast from said Pope's [[spoiler: {{Magitek}} staff]] (which incapacitates the other dozen or so people present), engages in a [[spoiler: {{Magitek}} Wizard's Duel]] with said pontiff, is [[spoiler:STABBED IN THE GUT by same]], before sucking it up and going on to [[spoiler:beat the aforementioned most powerful man in Europe to a bloody pulp with his bare hands]]. There is a reason he is named only one breath after Altair when someone talks about the greatest Assassins of all times.
** Shay from ''VideoGame/AssassinsCreedRogue''. The Assassins (the deadliest people on the planet) try to kill him and ''fail miserably''.
* Asura from ''VideoGame/AsurasWrath'', patron saint of UnstoppableRage. He gets killed ''four'' times, and every single time he escapes the underworld, even angrier than before. Hell, the only thing that kills him off for good [[spoiler: is killing Chakravartin, who is basically God!]]
* The first game with an Implacable Man was ''VideoGame/{{Berzerk}}'' and Evil Otto, who shows up if you are slow in clearing the room of robots. Not only was he invulnerable, but could pass through the electrified walls that would kill anything else that touched them, including the robots that were also trying to kill the player. Otto would also destroy any robots that were in his way, and in some rooms the only way to get the bonus points for killing all the robots was to lead Otto through a walled off chamber in which the last robot was hiding. Otto would gradually speed up over time, and instantly go to maximum speed (twice as fast as the player) once all robots in a room were destroyed, making death at his hands unavoidable unless the player was very close to an exit.
** In the sequel to Berzerk, Frenzy, Otto could actually be killed by four laser shots (either from players or robots). Every time he died, however, he would return from the same spot he spawned one second later, moving slightly faster than before. Killing him was worth quite a few points, but his movement pattern (bouncing vertically like a ball viewed from the side, even though the game actually used a top down perspective) made scoring hits very difficult unless directly above or below him, and this was the most dangerous place to be while fighting him due to the horizontal screen and the bouncing movement making Otto able to cover vertical distances much more quickly. It didn't help that missing Otto with a laser blast could result in the player's death from his own beam, due to new laser-reflecting walls present in the sequel. Finally, Frenzy included some special rooms, including the nightmare inducing "Mama Otto" room, dominated by a giant (but thankfully motionless) Evil Otto. Until you set it off...
* ''VideoGame/BinaryDomain'': Subverted with the rank and file robot mooks; sure, they'll keep shooting no matter how many limbs you blow off, but destroy their head and they revert to their default 'protect humans' mode, convincing them to spare you and kill the other robots[[note]]Just don't expect their backup systems to do more than walk and fire in the general direction of robots from their secondary sensors[[/note]].
* The ''VideoGame/BioShock'' series has one for each setting:
** Big Daddy in [[VideoGame/BioShock1 Rapture]] and The Songbird in [[VideoGame/BioshockInfinite Columbia]]. The former, an [[NinjaPirateZombieRobot underwater cyborg steampunk Papa Wolf]], is a loose example as he won't attack you unless you provoke him. You might assume from his dense armor that Big Daddy can't keep up a hot pursuit. You would be mistaken. There are several models throughout the game, and two variations (one with a drill, and another with a rivet gun.)
** The Songbird, a giant robotic sparrow who patrols the tower [[LivingMacGuffin Elizabeth]] is imprisoned in. It's only goal is to return Elizabeth to her gilded cage, meaning it's possible to appease Songbird by simply handing her over. It takes the entire game to finally turn Songbird to scrap metal.
** And then there is the Motorized Patriot, who in his introductory video is actually described as being this, He feels no pain, he does not falter, no sense of self-preservation, he has no CranialProcessingUnit, so really, you can shoot at him until he's dead but he will not stop.
* Hedrox in ''VideoGame/BloodRayne'' is an Implacable ''Vampire''. He is a beastial vampire monster with large claws and extremely powerful regenerative powers that make him immune to bullets and any blade damaged done to him heals very fast. Worse, if he gets dismembered, then several clones will emerge from the severed parts and create new Hedrox's that will keep pursuing you. [[spoiler:The only way Rayne can beat him is thinking outside the box and drop him into water, which burns vampires like acid. Even then, one of his copies survives and it takes being incinerated by the demonic BigBad to finally destroy him.]]
* Wilhelm in ''VideoGame/BorderlandsThePreSequel''. Most characters, when they run out of health, go into "Fight For Your Life mode", where they slump to the ground and frantically try and gun down targets until they either bleed out or score a kill and earn a "second wind". Wilhelm's "Dreadnought" skill tree, however, has a skill called "Termination Protocols". With this, instead of a normal FFYL, Wilhelm gets a shorter period of full activity where he keeps walking and killing normally, plus electrifies the area around him -- and if he fails to kill anyone in that time, he sets off a huge, if low-damage, explosion as a final "screw you" -- and can score a Second Wind off any of these.
* ''VideoGame/BrainDead13'': Fritz. No matter where you are, no matter how much distance you put between you and him, no matter what you have just done to him, no matter how many times he falls prey to the castle's other dangers and his own vast armament, Fritz is almost always five seconds away from killing you.
* Solus from ''VideoGame/{{Breakdown}}'' is indestructible to the point where all you can do is run, dodging laser traps only to see him just ''walking through them'' -- these laser traps would kill you the second you touch them, and yet he just walks straight through them without even a burn mark to show for it.
* ''VideoGame/ChzoMythos'' series:
** The Welder
** The invincible Tall Man. Depending on his mood, he'll just walk towards you, or teleport Manga/DragonBall Z style and butcher you effortlessly.
* ''VideoGame/CliveBarkersUndying'': The Covenant siblings cannot be killed by any mortal weapon, only with the Scythe of the Celt. Even then, Lizbeth's head snarls and spits at Patrick before he lights it on fire and throws it off a cliff.
* Scissorman from the ''VideoGame/ClockTower'' series, and the Subordinates from ''VideoGame/ClockTower3''. The stalkers from ''Ghost Head/The Struggle Within'' as well, zombies excluded.
* In ''VideoGame/CommandAndConquer'', Kane has survived being shot at by a giant space laser, and also being run through by a piece of debris. He comes back for yet another sequel. Where he gets shot by the space laser ''again'' and is [[VillainousBreakdown very angrily surprised]] when he finds out his followers thought it was going to stick this time.
* The King Tiger Tank in ''VideoGame/CompanyOfHeroes''. Its armor is so thick that no Allied tank can penetrate its frontal armor. It has a really powerful gun, multiple machine guns, and max veterancy. The only way to defeat it is to surround it with multiple tanks or to use its natural enemy in real life: bridges. Destroying a bridge with demo charges will oneshot it, just like anything else. There is a reason why calling this into battle is the last ability received on the [[http://www.gamereplays.org/companyofheroes/portals.php?show=page&name=company-of-heroes-terror-doctrine-units-abilities-strategy-tactics-guide&st=3]] terror doctrine commander tree.
** The lesser known Jagdpanther tank destroyer is also a bitch to kill.
* ''VideoGame/TheCrookedMan'': The titular character will ''never'' desist from chasing David until the good ending of the game is reached. He can't be killed before then due to [[spoiler: already being dead]].
* The Pursuer in ''VideoGame/DarkSoulsII'' "will not rest until his target is slain". He backs this up, particularly in ''Scholar of the First Sin'', by constantly dogging your steps, popping up again and again no matter how hard you put him down. In Scholar's NewGamePlus you can end up killing him nine times, more if you use bonfire ascetics. (That being said, part of this is a mistranslation from the original Japanese, in which the Pursuer is a member of an organisation of similar warriors, who are presumably the ones harassing you; in English, his boss soul's text implies he is a lone warrior with a particular grudge against those with the Undead Curse.)
* Combining this trope with RasputinianDeath, the Gibbering Prophet of ''VideoGame/DarkestDungeon'' is certainly made of this trope. He continuously warned the townsfolk of the Ancestor's evil and for being a harbinger of doom, much to the annoyance and worry of the Ancestor. The prophet faced StockPunishment, was thrown into icy waters to freeze and drown, and was stabbed multiple times with various weapons, but every time the prophet would come back and continue to decry him, and wear the knives and what remained of the pillory to taunt the Ancestor. It took a HannibalLecture and a showing of what exactly the Ancestor had planned to finally break the prophet, causing him to GoMadFromTheRevelation and end up becoming a boss you'd have to face.
* In addition to what has been mentioned about ''TabletopGame/Warhammer40000'', the ''Dark Crusade'' expansion to ''VideoGame/DawnOfWar'' gives [[OurElvesAreDifferent Eldar]] Fire Dragons the effective mass of super-heavy tanks without compromising their agility. Although they do not have the durability of most other examples on this page, the not-too-shabby health they possess results in a bunch of base-wreckers that can sprint through air strikes, artillery, orbital bombardment and God-Emperor knows what else without being tossed around like most other infantry. Yes, that list of infantry includes [[OurOrcsAreDifferent Da Ork Warboss]]. They form a point of contention regarding Eldar imbalance.
* The killers in ''VideoGame/DeadByDaylight'' are unable to be harmed or damaged in any way, although the survivors are free to disorient and slow them down using the environment. Even when caught in their own BearTrap, the Trapper just opens it up and sets it aside.
* ''VideoGame/DeadSpace'' has The Hunter, aka the Regenerator Necromorph, an artificial Necromorph created by the ship's resident MadScientist that steadily pursues you through the ship over several chapters. Notable for not only enduring all damage the player can inflict and brush off the effects of being cryogenically frozen, but after luring it into the path of a ship's thrusters and testing them, ''it can still be seen trying to crawl towards you as it melts to death''.
** ''VideoGame/DeadSpace2'' does this again through The Übermorph in the final chapters; whilst it is still relentless and able to regenerate limbs in moments, it is presented as an Elite Mook by sudden unexplained appearance (and by it functioning primarily as an invincible mook rather than a plot device like the aforementioned Hunter).
** ''VideoGame/DeadSpace3'' ups the ante by throwing ''several'' Regenerators at Isaac in one level. He remarks that he [[DemonicSpiders REALLY hates those things]]. They're put down for good when the docking bay vents and they wind up spaced (this doesn't kill Necromorphs, but a Necromorph floating in perfect vacuum isn't in a position to kill anyone).
* ''VideoGame/{{Destiny}}'' has The Vex, basically a race of Terminators that can keep coming after you even if you blow their heads clean off. While they can be killed, it's implied that destroying their physical constructs doesn't really do much to slow them down since [[spoiler: they can alter the flow of time and just call more troops in from the past, present, or future to throw at you. There is also the experiment they were working on in the Vault of Glass, which would have made their own existence and dominion over the universe a ''law of reality'', taking them up to true implacability.]]
* In the ''VideoGame/DevilMayCry'' series, enemies on [[IdiosyncraticDifficultyLevels Dante]] [[NintendoHard Must Die and higher difficulties]] have a [[SuperMode Devil Trigger power]] that they can use, making them nearly immune to flinching and much harder to kill. Vergil in the third title represents the Implacable Man ideal more accurately. When he uses his Devil Trigger (on ''any'' difficulty, BTW), he doesn't flinch from attacks, [[NighInvulnerability takes them without being scratched at all]] and [[HealingFactor regenerates health]]. While he can be knocked out of it, showing the state to be merely a brief flirtation, it is hard enough to do so. When he assumes the Super/Desperation Devil Trigger in the final fight, he can't be knocked out of it, but he does halt after some time, though not before regenerating at a higher rate than in his normal Devil Trigger.
** This is justified in that when ''you'' DT, you get the stun resistance yourself also, as well as the regenerative factor.
** Enemies? Dante gets impaled with his own sword in every installment. This somehow fazed him only the first time it happened. Must have been the novelty.
* In ''VideoGame/DisasterDayOfCrisis'', Ray is practically this -- he survives several natural disasters while fighting an elite former special forces unit, and he just still keeps coming after them on his own out of sheer willpower to save Lisa. Major Evans also has this trait, taking an ungodly amount of bullets to the face (and calls their first fight a ''draw'' after he takes so many bullets!), mans a Metal Gear expy while still taking even more bullets (or rockets) to the face, and can give Ray a hand-to-hand battle before [[spoiler:Colonel Haynes finally shoots him square in the forehead. That guy must have a really special gun]].
* The Cyberdemon in ''VideoGame/{{Doom}}'' can mow through masses of lesser mooks with its rocket launcher and {{One Hit Kill}}s the player unless your health and armor are at nearly 200%. It takes roughly 400 bullets to be put down, which is twice as many as you can carry without a backpack, and it's resistant to missiles[[note]] Specifically, it is immune to the splash damage that is normally what causes most of a rocket's damage output[[/note]], which are unfortunately the only kind of ammo that you'll find in its lair. The fact that you don't have the {{BFG}} at that point doesn't help. Not to mention it had better stats (health, speed, pain chance) than the final boss, who shows up one whole episode later.
* This trope is completely flipped on its head in ''VideoGame/Doom2016'' and ''VideoGame/DoomEternal'', wherein various [[EncyclopediaExposita Codex]] entries make it abundantly clear that [[PlayerCharacter you]], the Doom Slayer, are ''by far'' the most [[TheDreaded horrifying]] and [[OneManArmy unstoppable]] opponent that Hell has ever seen. Any attempt by any of Hell's leaders to bargain or plead with the [[NoNonsenseNemesis Slayer]] is silenced without a moment's hesitation. One level in the former game features the corpse of a {{Kaiju}}-sized demon, which the nearby lore tablet explains the Doom Slayer killed ''by himself'', armed with nothing but ''an ordinary sword and shield''.
* In ''VideoGame/DragonAgeOrigins'', the Arcane Warrior when built correctly becomes a virtual god. With right spells and a good armor, they will take practically zero damage against most enemies, even High Dragons. The rest of your party may be dead, including your tank, but Arcane Warrior will keep fighting. If you also give him/her Spirit Healer as a second specialization s/he will be practically immortal.
** [[PlayerCharacter The Warden]] is seen as this by many of their enemies. It doesn't matter what the enemies try in order to stop the Warden, they always keep coming. In fact, they even try to stop them by trapping them in the Fade in two different ocassions. They fail. Both times. Completely.
** [[ActionGirl Aveline]] from ''VideoGame/DragonAgeII'' is the game's resident StoneWall. In addition to the usual warrior skills, her special tree has skills which make her immune to every status effect in the game, including critical hits. After taking enough of this, the only thing that can stop her is magically lifting her from the ground and confining her in a telekinetic prison, and she has better-than-even odds of saving against it. An illustration: in a contest between [[UnstoppableForceMeetsImmovableObject Aveline and a charging Ogre]] (read: horned sixteen foot wall of muscle), when the two meet, Aveline will still be standing. The ''Ogre'' will be on the ground.
** ''VideoGame/DragonAgeInquisition'' has the Champion [[PrestigeClass specialization]] for warriors, focused on tanking. Along with abilities that boost their defensive and guard-building abilities, they have an activated ability that makes them completely invulnerable for a short period and a passive that makes them completely invulnerable [[CriticalStatusBuff when they would otherwise be reduced below 5% health]].
* In ''VideoGame/TheElderScrollsOnline'', BigBad [[OurGodsAreDifferent Daedric Prince]] [[TheCorrupter Molag]] [[GodOfEvil Bal]] creates an implacable BadassArmy out of the Xivkyn, a form of [[OurDemonsAreDifferent lesser Daedra]] Bal created by combining the [[GiantMook massive]] and [[EliteMooks powerful]] but unruly and [[ChronicBackstabbingDisorder untrustworthy]] Xivilai with the {{Proud Warrior Race|Guy}} [[TheLegionsOfHell Legions Of Hell]] Dremora (who refer to themselves as the "Kyn" in the Daedric language). The result is an implacable fighting force which very nearly takes over Mundus.
* ''VideoGame/{{Fallout}}'':
** ''VideoGame/Fallout2'':
*** There's Frank Horrigan, a 12 foot super mutant in PoweredArmor who laughs at the idea that plasma fire can kill him. It takes concentrated fire from several turrets and an Elite Mook squad to even have ''even'' chances.
*** The Great Khans are an entire organisation of this. Go ahead: march into their base and slaughter them to the last man -- this has happened twice in their history. There is always some survivor who runs off and reforms the Khans to continue their raiding.
** In ''VideoGame/Fallout3'', one can find audio logs detailing the experiments in Vault 92 aimed at using subliminal messages and infrasound to create obedient super soldiers incapable of feeling pain. The experiments were partially successful, with the test subjects requiring upwards of 20 bullets to put down, but also becoming violently unstable and eviscerating each other with their bare hands.
** ''VideoGame/FalloutNewVegas'':
*** Joshua Graham, the former [[TheDragon right-hand man]] of Caesar. NCR snipers have reported confirmed kills on him ''multiple'' times, only for him to reappear just fine a few days later. He was at Boulder City when the Hanlon's rangers blew it up. When he failed to win the Battle of Hoover Dam for the Legion, Caesar ''[[ThereIsNoKillLikeOverkill set him on fire and threw him into the Grand Canyon]]'' to ensure he'd stay dead. Then, just in case that didn't do it, Caesar sent assassins down after him to finish the job. [[AssassinOutclassin That didn't do it either]]. In ''Honest Hearts'', he has a Damage Threshold of 50, which is more than the biggest, heaviest, tankiest Power Armor in the game provides. His own armor is just a standard bulletproof vest worn over his normal clothes, which provides only 15 DT.
*** The [[PlayerCharacter PC]] "The Courier" also qualifies: at the start of the game, they are shot twice in the head by a 9mm at point-blank range (granted, [[LittleUselessGun you probably won't be able to kill anything with two shots from a 9mm either]]). After spending a few days in the local clinic, they get back up march out into the Mojave and slaughter everything in their path. With the DLC's included, they also have their brain, heart and spine removed and are actually better off for it (they have synthetic replacements installed), get stranded in a poisoned city filled with other unkillable monsters (see below), and simply walk away with all the guns and gold they can carry.
*** The Ghost People of ''Dead Money'', after years of exposure to the toxic cloud, are nigh-immortal. They silently stalk you through the city, unable to talk through the heavy clothing they wear, dragging travelers off to beneath the city to do... God only knows what to them. After being left alone for 30 seconds, a 'killed' Ghost Person will simply start up again like a wind-up Terminator. The only way to stop them is the four Ds: Disintegration, Decapitation, Dismemberment, and Dog (who eats them). And in order to get into the Sierra Madre Casino, you have to start up the Gala event. Which attracts the attention of every single Ghost Person in the city, including the ones underground. Have fun.
* In ''VideoGame/FarCry3'' Jason Brody makes just about everyone who isn't on his side assume that he is invulnerable [[spoiler: because Vaas' otherwise lethal bullet was deflected by a cigarette lighter. Naturally, everyone who knew about Brody's apparent death jumped to the extremely logical conclusion that he just came back to life]].
-->'''Vaas:''' The thing is... alright, the thing is: I killed you once already... and it's not like I am fucking crazy.
** Technically Brody does fulfill this trope, as Vaas foiled his attempts on revenge [[spoiler: three times: first by shooting Jason, second by kicking him into deep water tied to a cement block, third by stabbing him with a machete. Brody survives all of them and manages to kill Vaas (just a few minutes after being stabbed), where he (finally) falls unconscious and presumably nearly dies.]]
* A tradition of ''VideoGame/FatalFrame'' series thus far goes as this: Any hostile spirit that serves as the BigBad of the game is also unbeatable until the designated final battle against said ghost. This includes Kirie in ''[[VideoGame/FatalFrameI I]]'', Sae and the Kusabi in ''[[VideoGame/FatalFrameII II]]'', Reika in ''[[VideoGame/FatalFrameIII III]]'', Sakuya in ''[[VideoGame/FatalFrameMaskOfTheLunarEclipse IV]]'', and Ouse in ''[[VideoGame/FatalFrameMaidenOfBlackWater V]]''. (That said, Sakuya has a twist: You DO battle her weaker form early on and must defeat her to proceed, but then she TurnsRed and plays this trope straight.)
* Zouken Matou from ''VisualNovel/FateStayNight''. [[spoiler:He actually gets 'killed' so often and eventually so effectively by Kotomine that he moves his soul into the Crest Worm that was in Sakura's heart, at which points she rips it out. Then crushes it. And he's ''still'' not dead.]] Also Kotomine, who had his [[spoiler: heart ripped out and was still around two days later to kick Shirou's ass despite the latter's body currently turning into swords]].
* Alma from ''[[VideoGame/FirstEncounterAssaultRecon F.E.A.R.]]''. You actually do face her head-on at the end of the game... but even then, you don't so much defeat her, or hurt her, as vaguely annoy her into leaving you alone [[spoiler: by detonating a nuke on her head.]]
** It also appears to be [[spoiler:genetic. It does not matter ''how'' many clones, helicopters, or psychic phenomena you throw at the Point Man. He'll tear through it all without so much as grunting]]
* The ''Franchise/FinalFantasy'' series has various examples:
** ''VideoGame/FinalFantasyVII'': Sephiroth. [[DoomedHometown Destroying Cloud's hometown]] [[OutOfTheInferno and walking through the ensuing flames without a scratch,]] [[KillTheCutie killing]] [[LastOfHisKind Aeris]], [[WithGreatPowerComesGreatInsanity ascending to near godhood]], [[TheEndOfTheWorldAsWeKnowIt and trying to destroy all life]] shows how far he'll go to prove his desire to [[GodhoodSeeker "inherit" the planet he feels is rightfully his.]]
** Subverted with [[SpiderTank X-ATM 092]] from ''VideoGame/FinalFantasyVIII''. Despite its self-recovering system and its ability to ambush you during an escape from Dollet in a limited time that make you think you need to run, this giant spider can be destroyed for real, and you're encouraged to do so because of some extra See-D ranks. You just need enough firepower to blow it up before it can fully recover itself.
** ''VideoGame/FinalFantasyX'': Auron, a [[TheMentor veteran Guardian]] and BadassLongcoat [[spoiler: who died years before]]. He didn't like that, so [[spoiler: he ''willed himself'' back into existence]].
** Llednar from ''VideoGame/FinalFantasyTacticsAdvance'' received no damage at all if you try to attack him with ''anything''. [[spoiler:It was actually because of the "Fortune" law, so Ezel created an [[AppliedPhlebotinum antilaw card]], making Llednar vulnerable to any attacks.]]
* In ''[[VideoGame/DissidiaFinalFantasy2015 Dissidia Final Fantasy NT]]'', [[VideoGame/FinalFantasyVII Sephiroth]]'s playstyle is based around relentlessly chasing down his opponents. He can dash-cancel many of his attacks, and his EX Skill, JENOVA, slows down nearby opponents, making them easier to pursue.
* The Black Knight/[[spoiler:General Zelgius]] from ''Franchise/FireEmblem'' definitely qualifies. He's invincible to all but the main character's ''BFS'' (which you get in the last few chapters of the game...), at least in the first game. [[spoiler:A whole castle falls on him, and he comes back just fine in the sequel.]]
* All/most of the animatronics in ''Franchise/FiveNightsAtFreddys'' are this. In fact, the only thing that could stop most/all of them is getting scrapped/destroyed/burned alive. Honorable mentions go to:
** Freddy, Bonnie, Chica, Foxy, Golden Freddy and the Puppet try to kill the guard since 1983. They stopped it in 1993, only because the restaurants closed down for 30 years.
*** Bonnie the Bunny. In 1987, he lost his face and arm, but he ''still'' tries to kill the guard.
** The Mangle. It is a victim of '''''gigantic''''' BodyHorror, yet it still somehow walks. By 2023, the only thing found is it's mask, so you can imagine how much it took to finally stop it.
** The main four animatronics in ''VideoGame/FiveNightsAtFreddysSisterLocation'' are extremely desperate to escape the establishment. They eventually merge their wires and endoskeletons to become Ennard. And how do they escape once they became Ennard? ''Rip out our organs and skeleton only to replace it with themselves.''
*** They were stopped ''decades'' later by being burned alive.
* ''VideoGame/{{Gloomwood}}'': One of the things that makes the Goatman so dangerous is the fact that it will ''relentlessly'' chase the player around the area it's in. Lock the doors? It'll smash them down. Go to another floor? It will slowly home in on you and find you eventually. Try to run? It will make a mad dash forward and quickly begin to outrun you. It can be brought down in combat, but that's far easier said than done -- [[MadeOfIron it can survive upwards of]] ''[[MadeOfIron ten]]'' [[MadeOfIron shotgun blasts point-blank]] in a game where most enemies go down in a single shot.
* Aquiles from ''VideoGame/FobiaStDinfnaHotel'' is a mutant monstrosity who repeatedly comes after you, again and again, no matter how many times you try to put him down. He's fought as a boss around 6 times, and it takes [[DIsneyVillainDeath dropping him into a chasm of acid]] to kill him for good.
* Kratos from ''VideoGame/GodOfWar''. And when he does die, he just slaughters his way back to the land of the living.
** In ''VideoGame/GodOfWarPS4'', he finally meets his match in the Stranger, who pursues him across the Nine Realms and ''never'' gives up; even killing him ''three times in a row'' can't stop him, and the only way to progress the story is to toss him somewhere he can't get out of for a while, like the bottom of a ravine or Hel.[[spoiler: He's Baldur, the Aesir given CompleteImmortality by his mother's spell; until the enchantment is broken by him accidentally cutting himself on a mistletoe arrowhead, the worst anyone can do is toss him around.]]
* You as Aldo Trapani in ''VideoGame/TheGodfather: The Game'', despite his not-so-invulnerability in-game. Hundreds of enemy mobster corpses? Those [[TotallyNotACriminalFront totally-not-criminal establishments]] converted to the Corleone cause? All stepping stones on the RoaringRampageOfRevenge leading to Don Emilio Barzini, the man who [[YouKilledMyFather ordered your father's death]].
* Jake and Francis Fratelli in ''VideoGame/TheGoonies (NES)''. The sequel introduces a third brother, but he can at least be defeated.
* Assassins can become this in [[PlayerVersusPlayer PvP]] matches of ''VideoGame/GuildWars'' when they use their Shadow Form enchantment. It makes them completely ''invincible to every attack or spell in the game''. If an Assassin using this skill targets you in a match, your only option is to run. Unless you have a signet that can remove enchantments...
* ''VideoGame/HalfLife'':
** The G-Man is a variant: you don't fight him, but he does follow Gordon Freeman all over the place, finding routes through places that Gordon must fight through and getting to spots before Gordon can. However, if you do feel like popping off a few rounds at him before he disappears round whatever corner, they simply bounce off with the bullets-on-metal sparks effect and sound (at least in the original ''VideoGame/HalfLife1''; in ''[=HL2=]'', like all important or allied [=NPCs=], he simply cannot be hit by weapons).
** Gordon Freeman, the "[[RedBaron One Free Man]]" himself. By ''VideoGame/HalfLife2'' he is [[TheDreaded feared]] as a OneManArmy by the Combine, and [[HopeBringer worshipped as a hero]] by the humans in equal amounts.
* ''VideoGame/HauntingGround'': The game's main claim to fame is that the player is chased by this type of individual once a chapter. These beings have different approaches to chasing the heroine, such as their attention span or diligence in finding her hiding spots. The best one can do before their boss fight is to run away, or knock them out via dog-mauling or alchemic munitions.
** Debilitas (The Caretaker) serves as an introduction to the game's premise. He's not as durable or persistent as later stalkers can be, and can be knocked out somewhat more easily. That being said, he shouldn't be underestimated.
** Daniella (The Maid) is made of this trope; she is incredibly difficult to knock out, and when that's achieved, she gets up quite quickly. She will relentlessly stalk Fiona, pretend to not know where her hiding spots are and will purposely lock Hewie in rooms and attack him to draw Fiona out if she genuinely has no idea where she is. This is even lampshaded during her Boss Fight if she's knocked out:
---> '''Fiona:''' ''[in journal]'' Even ''that'' didn't stop her?! What is she, the maid from hell?!
* ''VideoGame/HelloKittyRollerRescue'' has this for a final boss; to win, you have to stall it until Keroppi can destroy it with a WaveMotionGun.
* Death (the security guard boss) from ''VideoGame/HouseOfTheDead 3'' shows up not just once but TWICE! One of the characters comments on its one-track mind and persistence.
* ''VideoGame/{{Iconoclasts}}'' has two examples, late in the game near the rocket.
** While you are trying to get the elevator working, [[spoiler:Black]] can not be stopped. Defeating the boss is not an option; you must fix the elevator and get out of there.
** A more classic version is [[spoiler:Elro, going up against Lawrence. Lawrence can shoot Elro, throw knives, punch him if he gets too close, but unless he runs out of HP, Elro keeps. On. Coming. Good thing you're playing Elro, and your job is just to No-Sell Lawrence's attacks while you keep marching up and stabbing him.]]
* The eponymous heroine of ''VideoGame/{{Iji}}'' winds up viewed this way by the enemy troops, according to their logs -- whether or not you're playing a pacifist run.
* [[NamesToRunAwayFromReallyFast The Beast]] from ''VideoGame/InFamous'' is [[AttackOfThe50FootWhatever a huge]] monster in the shape of a man seemingly made of lava. The military can't stop it, it just blows them into dust and keeps walking. Cole, the Electric Man himself, can't stop it, it just gets right back up after being hit by a storm of lightning called down on it from the sky. [[spoiler: A ''nuke'' going off in its face can't stop it, it just reassembles [[ComicBook/{{Watchmen}} Doctor Manhattan-style.]] The only way to kill it for good is to kill every Conduit on the planet.]]
* Death's Hand from ''VideoGame/JadeEmpire'', who is also ''TheDragon''.
* The Sheriff in ''VideoGame/LakeviewValley'' is not about to let a little thing like a shotgun blast to the face at point-blank range stop him from bringing anyone he can prove has broken the law [[JudgeJuryAndExecutioner to justice]].
* The Creator/{{Infocom}} InteractiveFiction game ''VideoGame/LeatherGoddessesOfPhobos'' has your henchman Trent (or, depending on a choice you make early in the game, Tiffany), who continuously dies in very unlikely ways and pops up again a few dozen moves later with an even more unlikely explanation for how he/she survived.
* Definitely fitting the description on later difficulties is the Tank from ''VideoGame/Left4Dead'', which can survive magazines upon magazines of high-powered rifle and shotgun rounds and complete immolation for upwards of a minute. Combined with how hard he swings, he is NightmareFuel.
** The amount of his HP varies from 4500 to over 6000, depending on difficulty, with a wee bit over five goddamn thousand in the Versus mode. When in doubt, KillItWithFire.
** Common Infected could occasionally become ''absolutely immortal'' thanks to a bug. Using a cheat engine that displays Infected health doesn't even give comforting high numbers (like 999,999), it reveals that they simply do not exist as far as the computer is concerned. AIs will simply give up and let the Implacable Zombie kill them, and the only way to survive is to shove it into a room, close the door, and rush through the rest of the level.
** Due to a bug in damage collision, it's entirely possible to hit a zombie with a melee weapon (almost always a one-hit kill on anything not a Charger, Witch or Tank) and see it's head get taken clean off, only to have the game register it as a miss. The zombie in question is perfectly killable if you can land a second swing, but until then it will come at you bleeding and without a head.
* ''Franchise/TheLegendOfZelda'':
** ''VideoGame/TheLegendOfZeldaTwilightPrincess'':
*** The Postman. It doesn't matter where you go, what you do, or what lies between you -- he ''will'' bring you your mail! Even if you pull off the glitch of making him fall into the abyss of Hyrule Field, he'll STILL bring you your mail.
*** The two Wallmasters in the Palace of Twilight. You can stun it with your Bow and Clawshot, but you can't kill it and it will KEEP COMING FOR YOU AS LONG AS YOU HOLD ITS SOL. Although, it'll give up after you go to the "outside" area and place the Sol in the ground.
*** Then there's the Bublin King, who you have to fight four times. And in two of the fights he falls into a cliff upon defeat.
** ''VideoGame/TheLegendOfZeldaPhantomHourglass'': The Phantoms cannot even be ''stunned'' until you get the bow about halfway through the game, and cannot be defeated until you get the necessary legendary sword shortly before the end of the game.
** ''VideoGame/TheLegendOfZeldaSkywardSword'':
*** The Cursed Bokoblins are described as returning from death by way of sheer hatred and will to mess up the world. And, supposedly due to a penchant for undergarments...
*** In the Silent Realm, there's two sorts of guardians; land based and flying. The land ones are faster and carry larger weapons, but they only pursue you when you're within a certain range. The flying ones, however, will ''never stop hunting you.'' They know where you are at all times and can phase through solid objects to hunt you down. They'll just keep following you until they eventually corner you.
* The Security Officer of ''VideoGame/{{Marathon}}'' is this trope to the nth degree. Depressurization, shuttle crashes, kidnappings, literal armies on all sides, torture, being stripped of all of his weapons and dropped on a DeathWorld, insane AIs, [[spoiler:''solar systems being blown up, '' and '''the literal embodiment of chaos itself.''']] All of them have one thing in common, and it's that they couldn't even come ''close'' to stopping him.
* ''VideoGame/MassEffect2'':
** Harbinger is relentless, focused, and entirely devoted to killing ''you'', ''personally''. Since [[VillainOverride he's remotely controlling]] the Collectors, he has no problems with letting you kill his current form and possessing the next one. In his own words, '''"I WILL FIND YOU AGAIN."'''
** Then in the [[DownloadableContent DLC]], Lair of the Shadow Broker, there's Tela Vasir. She gets tackled by Shepard out of a four story window, gets in a really nasty car wreck, loses an enormous amount of blood, gets slammed in the face by a flying table yet she still provides one of the toughest (and most awesome) fights in the entire series.
** The Shadow Broker himself probably counts. He fought you for a bit, got bored, and decided to activate his own personal shield, forcing you to hit him. [[spoiler: he only dies when Liara dumps a load of plasma on his head]].
** Shepard him/herself counts given how many cybernetic enhancements and upgrades have been put into his/her body over the course of the game and his superhuman determination to defeat the Reapers. Death isn't enough stop him/her. Probably best illustrated during the ''Arrival'' DLC, when Shepard forces his/her way to consciousness through increasingly high doses of sedatives, breaks out of his/her cell without weapons, and proceeds to ''[[OneManArmy single-handedly]] [[CurbStompBattle destroy the entire facility]]'' to keep the Reapers at bay. The mooks are absolutely terrified by him/her. Lampshaded during the main game by Garrus pointing out that the Reapers killing Shepard only meant pissing him/her off.
** Zaeed Massani survived being shot in the head. At the end of his loyalty mission, an enormous beam falls on his leg, which doesn't seem to affect him. He also killed a Krogan and all his Mooks.
--> '''Zaeed''': Rage is one ''hell'' of an anesthetic.
** Garm, the Krogan in command of the Blood Pack on Omega probably qualifies as this -- Garrus remarks on how quickly he can regenerate his health. In the end, it takes Shepard, Garrus and two other members of Shepard's crew to kill him.
** Krogan in general. More pronounced in the first game where they would get back up after death unless killed by ammo that caused disintegration.
* ''VideoGame/MaxPayne'':
** Max can get plugged with hundreds of bullets in the course of the games, but doesn't seem any worse off, as long as he has a supply of painkillers to dull the pain. Lampshaded by the BigBad of the first ''VideoGame/MaxPayne1'' and again by the BigBad of ''VideoGame/MaxPayne2TheFallOfMaxPayne'':
--->[[spoiler:'''Nicole Horne:''']] (''Max Payne'') What do you mean, "he's unstoppable"? You are superior to him in every way that counts. You are better trained, better equipped, [[JustOneMan you outnumber him at least 20 to 1]]. Do... your... job!\\
[[spoiler:'''Vladimir Lem:''']] (''Max Payne 2'') What the fuck is wrong with you, Max?! [[WhyWontYouDie Why don't you just die?!]]
** In the second game, he survives being shot ''in the face''. He doesn't become mentally disabled or dysfunctional from it, either.
* All rampant in the ''VideoGame/MetalGear'' series:
** Liquid Snake from ''VideoGame/MetalGearSolid'' survives a helicopter crash, an arseload of missiles that only succeed in blowing up his HumongousMecha '''while he is inside the said mech''', a forty foot fall from the top of yet again the same HumongousMecha after being punched off it during a fistfight, and then a barrage of gunfire to the face followed by a jeep crash. He is finally killed by a [[spoiler:tailored supervirus-induced heart attack.]] And then he [[spoiler:comes back in the sequel as a talking arm. But not really.]]
** Vamp from ''VideoGame/MetalGearSolid2SonsOfLiberty'' and ''[[VideoGame/MetalGearSolid4GunsOfThePatriots 4]]''. Survives being shot in the head and heart, filled with lead and dumped in a vat of no-resistance fluid, shot in the head again, stabbed multiple times (with he himself pulling a blade stuck in his chest out through his back), and shot a few more times [[spoiler: before the AppliedPhlebotinum keeping him alive is finally deactivated.]]
** Ocelot (before he gained the nickname "Revolver") in ''VideoGame/MetalGearSolid3SnakeEater''. While not entirely murderous, he seems obsessed with besting Snake after tasting humiliating defeat early in the story. However, he is hogtied by his own sense of honor, which forbids anyone else helping him (or Snake dying at anyone else's hands [[TheOnlyOneAllowedToDefeatYou but his own]]).
** Raiden becomes this in ''VideoGame/MetalGearRisingRevengeance''. Once he learns that World Marshall is planning to create an army of child soldiers using the same training regimen that was used on Raiden, he decides to take them down. And no one, not Maverick, not enemy cyborgs, not the [[QuirkyMinibossSquad Winds of Destruction]], hell; not even [[TheDragon Sam]] could stop him in their rematch. Oh, and Raiden can now slice open his foes and steal their nanotech to heal himself completely, making him even more difficult to stop.
** ''VideoGame/MetalGearSolidVThePhantomPain'' has The Man On Fire, a wraith WreathedInFlames with an EnergyAbsorption ability that can take '''any''' physical force you throw at him and send it back at you ten-fold. This can be anything from a sock to the face or small arms fire to taking an ''RPG-7, Sidewinder Missiles, and a goddamn '''tank shell''' to the face'', and being barely more than fazed before he unleashes death upon whoever tried to fight him conventionally. [[spoiler: His death didn't even come by conventional means, but after he realized that Venom Snake was not the person [[PowerOfHate fueling his rage]], and he basically ''shut himself down''.]]
* ''VideoGame/MetalSlug'':
** Humorously done by [[TheDragon Allen O'Neil]]. In the second game, he gets eaten by a killer whale upon defeat and ''still'' comes back for the sequels. When asked about his immortality, the game staff responded that the reason he never dies is because he both "has a body of steel and guts", and he has a wife and son to return to at the end of the day (a strange inversion of FatalFamilyPhoto there).
** When one of your OneHitPointWonder characters comes back from the dead -- either through using an extra life or using a continue -- all enemy soldiers on-screen briefly ''freak out'' over their inexplicable resurrection.
* ''Franchise/{{Metroid}}'':
** The SA-X in ''VideoGame/MetroidFusion''. Somewhat more complicated in that it's a copy of the heroine, with all the Metroid-killing equipment she wielded at the end of the last adventure. The real heroine starts off pitifully unpowered by comparison, and ''is now part Metroid'' to boot. Talk about stacking the odds against you. At first you can't do anything against it and just have to run away, but later on you can freeze it to slow it down.
** Samus herself is also an example. This is especially clear in the ''Prime'' series where you can read Space Pirate logs that speak of "The Hunter" as an unstoppable killer capable of obliterating their entire armies singlehandedly.
** The [[LifeDrinker Metroids]] themselves, unless you're packing a [[KillItWithIce cryo-based weapon.]]
** Dark Samus, a near unkillable doppelganger of Samus who thrives on Phazon and can come back FromASingleCell. Best displayed after beating her near the end of ''VideoGame/MetroidPrime2Echoes'', where she uses the last strength she has left to crawl towards Samus and attempt to grab her for one last attack before collapsing, eerily similar to [[Franchise/{{Terminator}} another Implacable Man]]. Then she returns in ''VideoGame/MetroidPrime3Corruption'', and [[HeroKiller is more dangerous]] [[TheChessmaster than ever.]]
* In ''VideoGame/{{Minecraft}}'' as long as healing crystals are intact, the Ender Dragon is unstoppable. If placed in overworld, it can fly right though anything that's not Obsidian, End Stone or Bedrock. Still feel secure in your cobblestone home?
* ''VideoGame/NetHack'' has the Wizard of Yendor. He's certainly killable, but that doesn't stop him from coming back to torment you all the way through the Elemental Planes, steal the [[MacGuffin Amulet of Yendor]] and create copies of himself to help with this.
* ''VideoGame/NeverDead'': The protagonist. Dismember him, run him over, or pierce him through. He [[ExactlyWhatItSaysOnTheTin never dies]].
* The Blood Hound is an enemy from ''VideoGame/ThePersistence'' who wanders from room to room on a deck hunting you down. It has by far the most health of any enemy and doesn't flinch upon being hit or shot in the head.
* ''VideoGame/Persona3'': [[TheGrimReaper The Reaper]], also known as "Death." It exhibits the "slow walk" by showing up whenever you take too long to advance to the next area. Even your support character warns you that you "can't defeat it!!", and tells you to get out immediately. It can be defeated it very high levels, but even if you do, it will still come back for more.
* ''VideoGame/Pikmin2'': The Waterwraith, is invincible unless you have purple Pikmin at your disposal. Unfortunately for you, you don't have any purple Pikmin when you enter the cave he dwells, and won't get access until you've reached the final floor.
* ''VideoGame/PlanescapeTorment'':
** The Nameless One, unless he wishes himself out of existence or screws up when meeting the BigBad.
** [[KnightTemplar Vhailor]] plays this trope as straight as can be. He is basically an avatar of Justice who will stop at nothing carry it out. He grows more powerful when hunting those who've committed greater crimes. [[spoiler:During your confrontation with [[BigBad The Transcendent One]], you can inform Vhailor about who you and The Transcendent One are, which transforms him into a [[WarGod God of War]]]].
* ''Franchise/{{Pokemon}}'': Primeape will beat the ever-loving shit out of [[HairTriggerTemper anything that pisses it off]], even if it has to chase it to the end of the world. But what ''really'' pushes it into this territory is the fact that, as of ''VideoGame/PokemonScarletAndViolet'', even death does not stop its rampage; it simply evolves into Annihilape instead, gaining the Ghost-type in the process.
* The Dahaka from ''VideoGame/PrinceOfPersiaWarriorWithin''. Subverted in that [[KillItWithWater it can be killed]], but there is only one weapon in the game that can actually do that and getting it is less than easy.
* In ''[[VideoGame/WingCommander Privateer]]'', later in the game when you find and equip the [[ImportedAlienPhlebotinum discovered Steltek gun]] on your ship, a Steltek drone will appear at random and attack only you. Your weapons won't scratch it, and although you may give it the slip using jump points, it will eventually show up again. You only finally get the ability to kill the drone just before the final mission [[spoiler:when an actual Steltek comes along and charges up the mounted Steltek gun to give it the ability to harm the drone]].
* ''VideoGame/{{Prototype}}'': Alex Mercer, and he's on a RoaringRampageOfRevenge all across Manhattan. He survives [[spoiler:being torn to pieces in the blastwave of a ''nuke'', regenerates FromASingleCell by absorbing nothing but a ''crow'', and states that his work is ''almost'' done. Not done. ''Almost'' done]]. Imagine being the guys assigned to take him down. Over the course of the game, he murders his way through what has to be three-quarters of [[SemperFi the marine forces]] -- by way of kicking their helicopters out of the sky, tearing their tanks to shreds with his bare hands, and ripping apart ''entire bases'' -- and comes out no worse for the wear. He ''is'' the Implacable Man. And he makes sure they ''know it''.
-->'''Alex:''' '''''NOTHING CAN PROTECT YOU FROM ME! NOT MEN! NOT WEAPONS! NOT ARMOR!'''''
* In the MMO ''VideoGame/RagnarokOnline'', the Monk character class gets access to the skill "Steel Body", or "Mental Strength" in one translation, that cuts all damage, magical or physical, to 1/10 if you have no vitality or intelligence, and if those two stats are high, any attack will do ONE damage! Another class (the tank furthermore) has a skill that does big damage in an area, but returns some to its caster. But a glitch can be exploited to make it HEAL you instead, thus doing huge damage to your foes while filling your own life gauge back up. In either case you get a nearly unstoppable character.
* ''VideoGame/Rayman3HoodlumHavoc'' has a level full of these called The Desert Of The Knaaren. The Knaaren are virtually indestructible, not even flinching from any attacks, and will chase you on sight. Word of advice: RUN.
* ''Franchise/ResidentEvil'':
** Lisa Trevor in ''VideoGame/ResidentEvilRemake'', though [[spoiler:thankfully she's not after you specifically but [[TearJerker just wants her mother]] -- she'll chase you when you enter her cabin or her territory in the caves, and she'll attack you when you're too close to the crypt where her mother's remains are, but if you leave the area she lets you go and if you open the crypt for her she morosely takes her mother's skull and retreats by hurling herself off the ledge never to be seen again by Jill or Chris]]. She shows up again, no worse for wear, in ''[[VideoGame/ResidentEvilTheUmbrellaChronicles The Umbrella Chronicles]]'' to chase Wesker, though this time is ''far'' more determined to hunt him down and kill him as she [[ItCanThink apparently recognizes him]] as [[ItsPersonal one of the men responsible for ruining her life and killing her mom]].
** Tyrants (games ''[[VideoGame/ResidentEvil0 0]]'', ''[[VideoGame/ResidentEvil1 1]]'', ''[[VideoGame/ResidentEvil2 2]]'' and ''[[VideoGame/ResidentEvilCodeVeronica Code: Veronica]]'') also count. You will always have to fight a Tyrant ''at least'' twice, and with the exception of the Proto-Tyrant in ''VideoGame/ResidentEvil0'', killing one ''always'' requires the use of [[StuffBlowingUp high explosives]]. Guns, grenades and ''immersion in molten metal'' will not be enough to kill one. Given that Tyrants are meant to be {{Super Soldier}}s, this is to be expected.
** The Tyrant T-103, encountered in [[NewGamePlus Scenario B]] of ''VideoGame/ResidentEvil2'', deserves special mention. He wants [[spoiler:Sherry's locket, which contains a sample of the G Virus]], and absolutely nothing will stop him from getting it. Towards the end Leon/Claire drops him into a smelting pit, and it ''[[TurnsRed only pisses him off]]''.
*** He's even worse in the [[VideoGame/ResidentEvil2Remake remake]], where instead of scripted events where he appears, he's always somewhere in the police station looking for you[[note]]There are still a few scripted events where he finds you no matter what, and it's rumored you can encounter two at once by happening to encounter the roaming Mr. X in the same area where a scripted encounter takes place[[/note]]. ''Always''. Shoot a gun nearby and he'll come running to investigate so you'd better keep moving. Worse still, pumping him full of bullets will only drop him to a knee stunned, giving you maybe half a minute at most to run away before he gets back up and resumes hunting. It takes a lot of bullets too, and they [[ImmuneToFlinching barely even stagger him]], so your best bet is to just run your fool ass off and hope you can ditch him. In short, he's become less of an Implacable Man and more TheJuggernaut.
** The Nemesis from ''VideoGame/ResidentEvil3Nemesis''. He's the only enemy in the game that can follow you from room to room ''and'' outrun you. It takes at least ''14 shotgun shells'' to kill him on ''EASY MODE''. No, wait, it gets better. [[spoiler:That doesn't actually kill it. You just knock it out. Nemmy'll show up later. Throughout the course of the game, he gets repeatedly shot, blasted out of a train with a grenade, has a rocket launcher blow up in his face, passes out into burning helicopter wreckage, soaked with acid, and by the end, he's been decapitated, falls into a pit of acid designed to break down [=BOWs=], and ''still doesn't stop''.]] Even worse, is this time he's after '''Jill''', not lashing out at all life, not trying to retrieve a locket, not "cleaning up" by killing generic cops or survivors, he wants the S.T.A.R.S. members specifically and he introduces himself by killing Brad, leaving you as the last and only one on his hit list. [[spoiler:During the boss battle against him as Carlos, he's more than content to walk right past the mercenary and into the room where the incapacitated Jill is unless you press your attack enough to [[RageBreakingPoint keep him focused on you]].]]
*** On top of that, in the ending [[spoiler:you must hit it with two shots from a railgun the size of a train car; and after that, you get the option to put six bullets right in its head. That finally kills it]].
** ''VideoGame/ResidentEvil4'' subverts this with the Regenerators. From the first meeting it seems that nothing can stop them... Unless you're ''really'' lucky with blind firing or high-end explosives, as it's later revealed that they simply have [[AttackItsWeakPoint hidden weak points]] that can be revealed with a special weapon. Bad guys like Mendez and Saddler, however, still play the trope straight, with Saddler [[spoiler: [[ImmuneToBullets ejecting the bullets from his body through his hands]]]]. And then there's [[ThatOneBoss El Verdugo]], though it is possible to finish the game without killing this guy, which is probably what most players do their first few times around. The Verdugo is ''so'' hard to kill, that some players are left with the impression that he's a HopelessBossFight and that he simply ''can't'' be killed, only escaped. He's more vulnerable under the effects of liquid nitrogen but it still takes a ton of firepower to take him down.
** [[BigBad Albert Wesker]] himself. He survived being slashed/impaled by Tyrant due to his regenerative PsychoSerum, and having a load of girders dropped on him, and can dodge bullets and catch rockets ''Matrix'' style. [[spoiler:Until he [[BodyHorror mutates]] into a OneWingedAngel form at the end of ''RE 5''.]] Even then he can survive the heat of lava, and takes a barrage of rockets to the heart before dying for good. [[spoiler:He plunged his hand into the container, laughing maniacally as the Uroboros swarmed up his arm.]]
** ''VideoGame/ResidentEvil6'' has Ustanak, the monster whose only goals are to brutally murder Jake and Sherry and try to outdo Nemesis for the coveted title of "Most Unstoppable Killing Machine". Even getting a DRILLING MACHINE THROUGH THE CHEST only takes him down for about 5 literal minutes. It also has the Rasklapanje, an {{expy}} of the Regenerator, who are fought in all the four campaigns. In a cutscene, Leon and Helena kill one only to watch it pull itself back together effortlessly. While it seems they can be killed by separating their body parts and killing each part individually, after sometime the parts revive and the creature reassembles itself. However, most of the times you meet them are in areas where they spawn infinitely, which makes going through the trouble of killing them a pointless endeavor.
** ''VideoGame/ResidentEvil7Biohazard'': Jack Baker, the patriarch of the [[CannibalClan psychotic]] and [[HealingFactor nigh-indestructible]] Baker family. Part one of the game involves you trying to find a way out of the house while he wanders around, chasing you if he sees you, and any attempt at fighting him will annoy him and waste your resources. It's only when you defeat him in an epic chainsaw duel that you put him down...[[spoiler: only for him to come back as a completely mutated mold creature for one more go at you. He seemingly dies for good after being calcified by a serum. In the DLC Chapter ''End of Zoe'', TheReveal is that the Swamp Man is none other than Jack. A document in this chapter explains that Jack's unique genetic makeup allowed his Mold mutation to give him a more potent Healing Factor, more so than any of the other members of the Baker family. Calcification is the nail on the coffin for those infected with the Mold, but he was able to survive and mutate again! Later on in ''End of Zoe'', his brother [[TheProtagonist Joe]] ''decapitates him'', but he reattaches his head off-screen and makes a comeback. Nothing short of a MegatonPunch from Joe with the [[PowerFist AMG-78]] to Jack's head actually kills him, causing it to ''[[YourHeadASplode explode]]'' and calcifying his remains.]] His wife Marguerite acts much the same way, but she usually relies on her insects to protect her and overwhelm her prey, and she's not nearly as stubborn as her husband.
** ''VideoGame/ResidentEvilVillage'' has [[OurVampiresAreDifferent Alcina Dimitrescu]] to fill this role. After a couple of scripted encounters, Lady Dimitrescu freely roams the castle just like the Tyrant in [=RE2=] remake and Jack Baker in ''[=RE7=]''. Unlike them though, her regenerative abilities are so strong that you can't even take her down temporarily; she just shrugs off any and all attacks (even from New Game+ weapons) without even blinking. [[spoiler:The only way she can be defeated is by stabbing her with a [[PoisonedWeapons poison dagger]] created specifically to kill her, and even then she keeps herself alive by mutating into her OneWingedAngel form for one last fight.]]
* The Ballistikraft robots from ''VideoGame/RiseOfTheTriad''. Invincible, hulking robots that roll towards you very slowly, shrugging off anything and everything you fire at it and spewing rockets at you. The only thing you can do is run.
* ''VideoGame/RuneScape'' had a couple of these guys that you saw that is implacable in general:
** First one is Lucien in While Guthix Sleeps, an evil [[ProudWarriorRaceGuy Mahjarrat]], during a cutscene where a series of heroes go and [[spoiler:try to]] fight the guy.[[spoiler:Needless to say, most of them [[HeroKiller bite the dust for good]] and [[KilledOffForReal they DO NOT come back]].]]
** Second Nomination will be the Corporeal beast, a result of NiceJobBreakingItHero. It comes to the corporeal realm to deliver a can of whoop ass for anyone willing to take a one way trip back to Lumbridge. Before it came to the corporeal realm, it was ''merely'' [[SealedEvilInACan trapped]] in the [[SpiritWorld Spirit Realm]], siphoning energy off the souls of a dead family for two quests. [[spoiler:And then you show up. Naturally, living soul energy is much more potent than dead soul energy...]]
** The final nomination will be [[OurVampiresAreDifferent Vampyres and Vyrewatch]], monsters that can't be beaten with even a [[InfinityPlusOneSword Godsword]], instead until you have a silver weapon, good luck fighting these guys. Even then, merely silver weapons will only work on Juvinates, the weakest form of the species; anything higher than that has limited mind reading and impossibly good reflexes, meaning any weapon with a predictable pattern (that is, all of them except a flail) can't even hit them to begin with.
** On the flip side, there's you, the player character. While quests generally act as if you don't die and do entire sections in one trip rather than individually (such as the finale of Dragon Slayer 2), you're known to be a warrior on par with the Wise Old Man and Robert the Strong, able to slay a Dragonkin's finest creation, which is so strong it can take out a Dragonkin itself in one blow[[note]]Robert the Strong is famous for being capable of killing Dragonkin ''at all''[[/note]] and a corrupted fragment of a god, capable of getting around any obstructions regardless of what they are, and being one of the few characters capable of canonically surviving dying.
* The Death spell in ''VideoGame/{{Sacrifice}}'' summons TheGrimReaper temporarily, who is treated by the game engine as a spell effect and not a creature; he cannot be targeted, shielded against, blocked, halted or damaged in any way, and will not stop hunting his target until he has killed it. If Death targets one of your creatures and you teleport away with it to the other end of the map, Death will immediately realign his course and slowly start following, ignoring everything else in his path.
* Both in and out of gameplay in the ''VideoGame/SaintsRow'' series, assuming you do enough diversions. Blowing up The Boss just gets them pissed off, and in the second game, the full complement of perks means that The Boss can jump out of a plane, get hit by three exploding trucks [[IncendiaryExponent on fire]], and take a point-blank shotgun blast to the face without going down. ''VideoGame/SaintsRowTheThird'' turns this [[ExaggeratedTrope Up to Eleven]] once you get close to max respect, with several upgrades making them immune to each type of damage. It can get to the point where The Boss can only be harmed by melee attackers.
* ''VideoGame/ScarfaceTheWorldIsYours'':
** Tony can enter a [[SuperMode Blind Rage]], where he exhibits true Implacability. He becomes immune to attacks, doesn't flinch, gains auto-aiming and the quasi-vampiric ability to heal by attacking enemies. Although it lasts for only brief periods, it can be reused and the meter needed to fuel it can be filled up fairly quickly. For that matter, Tony in general; he's gonna take Miami back and kill Sosa, and heaven help the [[ForeignCussWord chazzers]] stupid enough to get in his way.
** BigBad Alejandro Sosa exhibits apparent-Implacability the way Tony did at the end of the film, taking whole clips to the chest without flinching. Even from the mighty [[HandCannon Desert Eagle]] that instant-kills everyone else. [[BoomHeadshot A good few headshots]] are needed to end him.
* As [[DigitalPiracyIsEvil an anti-piracy]] measure, ''VideoGame/SeriousSam 2'' will [[DevelopersForesight set one of these loose on you if it detects a pirated copy of the game]]: An indestructible [[LightningBruiser lightning-fast]] giant-scorpion creature will follow you from practically the start of the game. It can't be killed and it's too fast to escape from for long. Of course, this merely [[DoNotDoThisCoolThing spawned a sub-set of players who seek out pirate copies just to see how long they could last against the beast]].
* Fox Face from ''VideoGame/ShadowHearts1''. If your Malice meter is filled, he ''will'' appear and hunt you down. You can beat him, but he will come back again and again, until you either clear the Malice or die.
* Most of the colossi in ''VideoGame/ShadowOfTheColossus'' qualify for this, with the only exceptions being Avion and Phalanx. Once the others have spotted Wander, they will not stop trying to attack him until he becomes physically inaccessible, dies, or kills them. Particularly notable is Dirge, which is reputed as being unique in that it is the only Colossus who seems to genuinely hunt Wander in order to devour him rather than just try to kill him. In fact, the reason Dirge's [[GlowingEyesOfDoom unnervingly large eyes]] are always [[RedEyesTakeWarning orange]] is because it is one of the few colossi who is ''constantly'' attacking.
* ''Franchise/SilentHill'':
** ''VideoGame/SilentHill2'' has the Pyramid Head: Usually the only way to survive an encounter with him is to run your damn fool ass off, and hope he doesn't catch you. The game suggests the Pyramid Head is merely a gatekeeper whose purpose is to herd you in the right direction. He is never truly defeated; he merely strolls away menacingly or kills himself once his purpose is fulfilled. In that sense, he is closer to a Juggernaut.
** Walter Sullivan from ''VideoGame/SilentHill4'', at least until the boss battle when his defenses are finally lowered. The Ghost Victims of the game also apply, since they will keep chasing Henry from level to level unless pinned down by a (very rare) sword.
* Officer Carmelita Fox from ''VideoGame/SlyCooper''. Wherever Sly is, Carmelita soon follows in hot pursuit.
* In ''VideoGame/SonicAdventure'', Dr. Eggman's robot ZERO chases Amy in every level for the bird with her, and whenever Amy loses ZERO, he soon catches up. [[spoiler:His tenacity even after his target has been obtained and is no longer of use to Eggman gets him killed.]]
* Played with in ''VideoGame/SouthOfReal''. Yes, the shadows are chasing [[PlayerCharacter Alex,]] but all they want is a lovely little family reunion. You happen to be still alive, but don't worry--they can fix that.
* ''VideoGame/StarCraftI'': The Torrasque is a special, one-of-a-kind super-Ultralisk that just gets reincarnated back at the base when it's killed, over and over and over again. It makes a return in ''VideoGame/StarCraftIIHeartOfTheSwarm'' as a possible mutation for all of Kerrigan's Ultralisks: the ability to revive once upon death.
* ''Franchise/StarWars'':
** ''VideoGame/JediKnightJediAcademy'' has four levels that involve different variations of the theme of an enemy (or several) chasing you that can't simply be killed, and three of the enemies fit this trope.
*** The sandworm will eat you in one bite if you stay on the sand long enough.
*** The rancor. If you actually want to kill it, it's harder than many boss battles... and when you do kill it, another one replaces it. So you'll end up avoiding it anyway. Its powers of following you are less impressive, as it gets lost and can't fit under doors.
*** Boba Fett. He's opposed to the idea of your finishing your mission, so he'll pit his BadassNormal powers against your Jedi ones at every turn, only to fly away if you manage to damage him enough and return soon after returning to full strength.
*** And finally, the mutated rancor. It's practically Godzilla, and it's completely immune to damage, so it's actually TheJuggernaut as well. Breathing poisonous gas and flailing at things, it will follow you all over the complex in the level, its steps making the floor quake, and demolish the scenery and [[HoistByHisOwnPetard eat the badguys who released it]] when it can't find you. When you find a way to sneak into the next hall through an exit it can't fit through, it will bang the wall until it yields and resume pursuit. [[spoiler: At the end, you'll be able to kill it by crushing it on a conveyor belt between a giant crate and an energy field that only lets giant crates through.]]
----> '''Jaden Korr:''' What did I ever do to ''him''?
** In ''VideoGame/KnightsOfTheOldRepublic'', Darth Malak sets the entire Star Forge against the protagonist, sacrificing thousands of his own men with the sole intention that it might potentially ''slow'' them down. Part of the reason such [[ThereIsNoKillLikeOverkill overkill]] is justified is because he's facing [[spoiler: an amnesiac Darth Revan, his former Master]]. Darth Sion from [[VideoGame/KnightsOfTheOldRepublicIITheSithLords the sequel]], who you can only kill by [[spoiler: [[WarriorTherapist convincing]] him that his life isn't worth living]]. According to the KOTOR Campaign Guide, Sion was once a living man, filled with so much hatred that when he finally was killed, his hatred and strength in the dark side allowed him to keep living, AND kill his assailant RIGHT THERE ON THE SPOT. He is bound together purely by his hatred. Oh, also, according to the medical records aboard the ''Harbinger'', his flesh has been cut into a bunch of rotting chunks that now make up his body, and and each of his bones has been absolutely splintered and pieced back together.
* ''VideoGame/StreetsOfRogue'': The Killer Robot Disaster has HP in the ''thousands'', and will slowly march towards your character while shooting an unlimited supply of rocket-propelled grenades. It cannot be hacked, possessed, or bribed to leave, but it is susceptible to water -- barely. Most players just try to get their chores done so they can leave the floor as soon as possible.
* ''VideoGame/StringTyrant'': Has The Stranger, an ominous trenchcoated figure that will continually search for Mary. It respawns about 20 turns after defeat stronger than ever. [[spoiler: It's finally defeated by using a church's bell to shake it to pieces.]]
* The Inspector and his dog in ''VideoGame/SubwaySurfers'': No matter how fast or far you're running, no matter how big a lead you get, thanks to a jetpack or mega-headstart powerup -- one stumble and The Inspector will appear right on your heels.
* Luca Blight from ''VideoGame/SuikodenII''. Just look at [[NoOneCouldSurviveThat what it takes to finally kill him]]; it includes several battles against several elite warrior squadrons (plural) whaling on him, enough arrows stuck in him to build several houses with and one final duel with the opposite army's champion, and even then he goes down laughing because it took ''that'' much.
* ''Franchise/SuperMarioBros'':
** In ''VideoGame/SuperMarioBros2'', there's Phantos, the creepy EvilMask that guards keys. If you take a key its guarding, it comes to life and chases you non-stop. It can't be killed (unless you grab a Starman) and the only way to shake it is to drop the key, although this is a temporary solution, because picking the key up again (and you'll always need it) causes the thing to resume the chase until you reach the key's door.
** [[TheUndead Dry Bones]] take as many jumps as you can dish out and still come back for more, that is unless [[spoiler: you had [[GameBreaker an invincibility star or a cape]] from ''VideoGame/SuperMarioWorld'']]. In ''VideoGame/SuperMarioRPG'', however, jumps are considered magical attacks, which Dry Bones are very weak to. As such, they can be felled quite easily with a single jump, whereas physical attacks such as Mario's punches, hammers and shells cannot do shit to them. It's ''still'' only enough to take them down only temporarily: about 10 seconds after the fight and they'll get right back up and come after you again.
** In ''VideoGame/PaperMario'', Jr. Troopa takes everything you can dish out and comes back for more time and time again. If you use Goombario's tattle ability, he'll keep getting more impressed with Troopa's tenacity each time. Tubba Blubba is completely unstoppable until you find his heart and make him mortal again. Mario and co. are aware of this, and immediately run for their lives in a chase sequence when he catches you in his castle. Attempting to attack him at this point is an unwinnable battle.
** ''VideoGame/SuperMarioBros3'': Chain Chomps don't like Mario standing there staring at them; they'll keep launching themselves at him over and over. After the 46th launch, the chain starts flashing to show it's weakening... And the 50th launch will '''[[OhCrap snap the chain]]'''. The now-free Chomp will pursue you quite fast, taking huge leaps where necessary to catch up and bite you, its tormentor. ''VideoGame/SuperMarioGalaxy2'''s Chomps cannot be stopped except by an invincibility star.
* David Leatherhoff of ''VideoGame/SvenCoop''. Admin-controlled, he's on the players' team so friendly-fire is impossible (against him, that is). David is by no means "friendly" and will relentlessly stalk and harass the players no matter what.
* ''VideoGame/TeamFortress2'':
** The mod "Freak Fortress" pits the entire team against one of these, which can vary from [[BadassNormal psychotic offshoots of the main characters]] to [[HumanoidAbomination full-blown monstrosities]], but will always be ''[[DamageSpongeBoss really]]'' tough, and strong enough to one-shot almost anything.
** In Mann vs. Machine mode, some of the harder rounds feature a [[GiantMook Super-Huge]], [[KingMook Super-Strong]], Super Unstoppable Robot--they can only be knocked back by the Heavy's Rage powerup, and (excepting Giant Scouts) will simply ''walk over'' any obstacles that they can't immediately destroy.
** Furthermore, a Medic with the stock Medigun can make himself and his current healing target Implacable Men (or Implacable Man and [[AmbiguousGender Pyro]]) for several seconds at a time, thanks to his Ubercharge ability (though they can still be bounced around by airblasts and bombs). [[TheBigGuy Heavy]] says it best.
--->'''Heavy, being Ubercharged:''' Is good time to run, cowards!
** Parodied by the Soldier with one of the lines he speaks while wearing his [[PaperThinDisguise cardboard robot costume]]: in an [[LiteralMinded overly-literal]] reinterpretation of the page quote, he claims: "I will find you! That's what I do! That's '''all''' I do! THERE YOU ARE! ... ''Shutting down''..."
* ''VisualNovel/{{Tsukihime}}'' has a few of these as well.[[spoiler:From Arcueid being cut into 17 pieces and coming back to life the next day, Roa being taken down to nothing but his ankles and immediately regenerating, and Nero having his body ripped in two only to make fun of the person who did it. They have this trope covered.]]
* [[spoiler: The PlayerCharacter in]] ''VideoGame/{{Undertale}}'' [[spoiler:''canonically'' has the ability to load their save file upon death through [[{{Determinator}} Determination]], meaning that killing them will only slow them down until they learn your patterns and breeze past you without you even touching them. They especially resemble this trope in the genocide route, where they will [[LevelGrinding walk around in circles and kill anyone unlucky enough to cross their path]] and only move on once the area is devoid of life. On top of their effective immortality, they become so powerful later on that they OneHitKill would-be [[BossBattle bosses]] with [[ThereIsNoKillLikeOverkill millions of damage]]. What most players consider to be the hardest boss in the game, [[BewareTheSillyOnes Sans]], knows that it's impossible to actually beat you, and instead attempts to wear you down mentally by killing you repeatedly and guilt-tripping you so that you eventually give up. As his final "attack", he simply doesn't take his turn, thus trapping the both of you there for all eternity until you get bored and quit. But even the ''RULES OF THE GAME'' aren't enough to stop you, as you push the bullet box over to the fight button and strike Sans twice in a row, finally landing a hit and one-shotting him.]]
* Selvaria in ''VideoGame/ValkyriaChronicles'' is this when her Valkyrian powers are activated. No attacks you fired at her did any damage. When she showed up, your only option was to make your units take cover and hurry to finish the objective. Even when she isn't a Valkyria, she's still pretty powerful.
* After it is released in the third section of ''VideoGame/VivisectorBeastWithin'', the Overbrute Panther becomes an Implacable Man; while you can blast whole chunks out of it, it won't be slowed one iota by it, and will instantly regenerate, and unless you find some way of locking it out temporarily, it will ''always'' catch up with you and kill you with a casually-placed detonator to the chest. Oh, and it can turn invisible at will, as well, to both sight and radar, making it even harder to avoid the monster. Games designers are sadists, clearly.
* ''VideoGame/{{Warframe}}'' features the Stalker, a creepy-looking warrior in black carrying a decent scythe and one of the best bows of the game. He marks you for death everytime you kill a boss (killing more bosses, even for farming purposes, just adds more marks) and has a random chance to appear during almost any mission. He'll make himself known by flickering lights and taunting you over your comms, then lock you in your current room before teleporting inside. Either you kill him, either he kills you. No other alternative. And he can walk his talk, being able to tear apart players who aren't carrying high-quality gear. Think the mooks or your allies will stop him? He will just ignore or (if attacked) kill everything in the room if it means getting to you. And after [[spoiler: you do the Second Dream quest]], he turns into the even stronger Shadow Stalker.
* Wario in ''VideoGame/WarioLand'', where he has infinite health. The main gimmick is that he ''has'' to hurt himself with the various obstacles and enemies in order to solve puzzles.
* You as Rubi in ''VideoGame/{{Wet}}'', you will regularly tear through rooms stacked to the brim with {{Mooks}} and survive. A more pure example is the ending, [[spoiler: where Pelham sicks his pet Albino Tarantula on you. After you kill her, you come after Pelham and he tries shooting you, it doesn't work and you behead him]].
* ''VideoGame/{{Wick}}'' features a family a murderous ghost children that pursue the player relentlessly, but special mention goes to Caleb. Once he spawns on the map he slowly, but surely digs towards the player until the hour is up.
* Asgard in ''VideoGame/WildArms3''. Guns and spells? Barely fazes him. A structure collapses on him? Minor inconvenience. Sending him to the distant past? [[TheSlowPath Ha ha, yeah right]]. The only reason you even manage to kill him [[spoiler: [[SuicideByCop was because he allowed you to kill him]] [[ICannotSelfTerminate so he can follow his masters to hell]]]].
* ''VideoGame/WorldOfHorror'' has the being known only as Something Truly Evil. If you're unfortunate enough to attract its attention, it starts popping up in other random encounters, relentlessly stalking your character until it finally attacks. When it does, you're [[HoplelessBossFight unable to harm it or run away]], and your only options are to sacrifice your Health and Reason until you either perish, go mad, or manage to appease Something Truly Evil and it lets you go.
* While Death Knights in ''VideoGame/WorldOfWarcraft'' are [[MightyGlacier not very fast]], they are hard to slow down: Wraith Walk resists snares, Icebound Fortitude cancels most stuns, Pillar of Frost [[NoSell No-Sells]] knockbacks, and [[AntiMagic Anti-Magic]] Shell is a Swiss army knife for ignoring control effects.
* The Lobstermen of ''VideoGame/XComTerrorFromTheDeep'', like their predecessors the Chrysalids, will give this impression when you first encounter one. You fill it with harpoons, your squad opens fire with Gauss pistols, you launch torpedoes at it... and you watch in horror as it somehow survives it all and proceeds to mow down your troops.
* ''VideoGame/{{Xenogears}}'' has Ramsus. The guy's been blown up, had his HumongousMecha thrashed repeatedly, and nearly drowned. Yet all of that doesn't stop him from trying to fight his rival [[LetsPlay/TheDarkId FEEEEEEEIIIIIIIIIIIIII!!!!]]
** Id. If he has to "step in" to handle [[spoiler: Fei]]'s problems... everything in sight is going to be very dead very soon. Including ''an entire continent'' except for one person, a small village, a fortress city of TheEmpire, entire fully armored batallions...
* ''VideoGame/Yakuza0'': Yoneda, Kuze's NumberTwo, becomes a recurring enemy throughout Kiryu's rampage through Dojima HQ at the start of the game. No matter how many times Kiryu knocks him flat on his ass or uses him to [[OpenSaysMe unlock doors]], [[MadeOfIron Yoneda will get back on his feet within minutes]] and attempt to ambush Kiryu while he's distracted. It takes Kiryu smashing his face against a urinal and [[DivingKick dropkicking]] him [[DestinationDefenestration off a fifth story window]] before Yoneda stays down for a meaningful amount of time.
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