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* ''VideoGame/WildArms1'' reveals this to have been the case with [[spoiler: Zepet Roughnight in regards to Rudy. Knowing Rudy is an ArtificialHuman created for the sole purpose of fighting the demons (and thus having a lot of destructive potential within him), Zepet raises him to be kind and gentle towards others. Rudy not only turns out to be one of the nicest and most selfless people in Filgaia, but he ends up [[ContagiousHeroism bringing out the best in those around him.]]]]

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* ''VideoGame/DirgeOfCerberus'': Once Shelke is captured by the WRO, Shalua works on deprogramming the EmotionlessGirl from her decade's worth of mental conditioning.



* ''VideoGame/DuskDiver'': After learning that [[spoiler:Nemea plans to merge the dimensions together]], Yumo sets out to sway them off their intended path.



* ''VideoGame/ShanghaiEXEGensoNetwork'': Reisen is a former [[ChildSoldiers Child Soldier]] whom Eirin adopted after meeting her as a field medic. She asks Alice and Shanghai to help her by making amends and becoming her first friends.




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* In ''VideoGame/TheValeShadowOfTheCrown'', Ainsley's brother Finn is being mind-controlled by the Baker and forced to fight. However, [[spoiler:Ainsley getting hurt]] helps shock him back to some degree of his original self.
* ''VideoGame/ValkyriaChroniclesII'': Dr. Foerster was grooming the 13-year old Aliasse into becoming a [[PersonOfMassDestruction devout Valkyria]]. Then she encountered Class G, who started teaching her how to be human, leading her to vow that she'd only use her abilities for the sake of defending her newfound friends. As a result, [[spoiler:her [[AbusiveParents 'mother']] decides that [[YouHaveOutlivedYourUsefulness she has no more use for her]] and abandons her]].
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DefusingTheTykebomb in VideoGames.
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* In ''VideoGame/BlazeUnion'', we learn that ''VideoGame/YggdraUnion'''s HeroAntagonist Gulcasa was technically ''born'' one of these--his mother attempted to defuse him by forcibly sealing his abilities and then [[ParentalAbandonment leaving him]] to go FindTheCure. His father, resenting him for the loss of his wife, started abusing him, and any good the seal did was undone posthaste. [[AllThereInTheManual According to]] WordOfGod, the young Gulcasa was a bitter and violent EmptyShell until Siskier and Jenon befriended him and helped him learn to be a normal little kid again.
* In ''VideoGame/CryingSuns'', one of the potential bosses in Chapter 4 is a child’s BrainInAJar, wired into the controls of a battleship and given doses of [[FantasticDrug Special-H]] for winning battles. The player character is horrified by this and offers to help return the child to normal. Unfortunately, the child has come to ''like'' its new existence and rejects your offer, attacking you.
* In a particularly odd case, [[LadyOfBlackMagic Morrigan]] from ''VideoGame/DragonAgeOrigins'' ends up defusing ''herself''. Once she realizes her mother's plan for her - [[spoiler:becoming a future host body]] - she starts plotting her death. In the first game's last [=DLC=] story, she heads for parts unknown with her own secret agenda, which may involve co-opting her mother's other big plan ([[spoiler:the Old God Baby]]).
* ''Franchise/FireEmblem'':
** In ''[[VideoGame/FireEmblemTheBlazingBlade The Blazing Blade]]'', in a variation for this trope, Jaffar was raised this way but is a grown man before interactions with Nino turn him good, and even then [[spoiler: only because the people he works for are about to kill her.]]
** In ''[[VideoGame/FireEmblemMysteryOfTheEmblem New Mystery of the Emblem]]'', the [[HelloInsertNameHere Avatar]] does this for [[spoiler:Katarina]].
%%* ''VideoGame/KnightsOfTheOldRepublicIITheSithLords'': The light side path with Visas.
* A Paragon Commander Shepard has this effect on [[AxCrazy Jack]] in ''VideoGame/MassEffect2''. She has way too many issues for you to deal with all of them in the game's time-frame, but you can at least convince her there are ways of solving problems besides shooting people. Which is why you get to keep it up in ''VideoGame/MassEffect3'', where she has mellowed out and is much more rounded as a person. This is to the extent that she has an effective family in her biotic students, teenagers that [[MamaBear she would do anything to protect]]. However, it can also be {{Averted}} in the third game if you [[spoiler:ignore the Grissom Academy mission past a certain point: the mission will be considered failed, the station is taken over by Cerberus and Jack is captured, where she is brainwashed and becomes an EliteMook [[TearJerker in the penultimate level of the game]]]].
%%* Snake sort of plays this role in ''VideoGame/MetalGearSolid2SonsOfLiberty''. Maybe.
* The player character of ''VideoGame/PokemonBlackAndWhite'' does this to [[spoiler:N Harmonia, ''before he is even known'' to be a TykeBomb]].
* A child soldier has to be talked out of culling the nurse with a pair of scissors in ''VideoGame/TraumaCenter: Under the Knife 2''.

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