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* EldritchAbomination: In ''Final Transmission'' an audio log from Mahler speculates [[spoiller:that the Biophage is a single intelligent entity and older than the known universe]]. Exactly what caused her to reach this conclusion is not overtly stated.
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* ImmuneToBullets: A good number of them are bullet sponges but not inherently immune.
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* ImmuneToBullets: A good number of them are bullet sponges but not inherently immune. However much of this comes from your overall lack of ammo and the fact for much of the game your guns tend to be on the smaller side (a pistol and a homemade sawed-off showgun). Unload on them with an assault rifle and they go down after about the same amount of lead as enemies in many other video games.
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* FacialHorror: The right side of his face is mutilated after the ship crash, with the ''lower half of his jaw'' hanging loosely from being severed.
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* ImmuneToBullets: Played straight in his first form. Jacob's ranged attacks only briefly daze him at best, but mostly just piss him off. This extends to gameplay as well; he isn't staggered by gunfire like regular Biophages are, and he's also ''extremely'' resistant to bullet damage, requiring over 100 rounds of fully upgraded assault rifle fire to end the fight both times you fight him (whereas if you stick to melee attacks he's only got about 3 times the health of a regular Biophage). Even in his second form (which can ''only'' be defeated with firearms or explosives) only his head is vulnerable, and he covers it with a fleshy armor dome that needs to be shot off.
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* ImmuneToBullets: Played straight in his first form. Jacob's ranged attacks only briefly daze him at best, but mostly just piss him off. This extends to gameplay as well; he isn't staggered by gunfire like regular Biophages are, and he's also ''extremely'' resistant to bullet damage, requiring over 100 rounds of fully upgraded assault rifle fire to end the fight both times you fight him (whereas if you stick to melee attacks he's only got about 2 to 3 times the health of a regular Biophage). Even in his second form (which can ''only'' be defeated with firearms or explosives) only his head is vulnerable, and he covers it with a fleshy armor dome that needs to be shot off.
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A Biophage-mutated Dr. Mahler serves as the FinalBoss of the ''Final Transmission'' DLC and the ''Callisto Protocol'' storyline as a whole, transforming into a powerful and unique Biophage mutant after being infected and thrown down a garbage incinerator by a Big Mouth. Jacob Lee fights her in one final battle before finally departing Callisto once and for all.
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A Biophage-mutated Dr. Mahler serves as the FinalBoss of the ''Final Transmission'' DLC and the ''Callisto Protocol'' storyline as a whole, transforming into a powerful and unique Biophage mutant after being infected and thrown down a garbage incinerator by a Big Mouth.one of the Biobots. Jacob Lee fights her in one final battle before finally departing Callisto once and for all.
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* PunchClockVillain: While he is certainly an ass, he never goes out of his way to KickTheDog, and is willing to be friendly with Jacob until the warden requests he be detained. [[spoiler:He only really starts getting aggressive with Lee after things have gone to hell, and considering how Jacob sent a pack of biophages at him as a distraction, this is understandable]].
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* PunchClockVillain: PunchClockVillain:
** While he is certainly an ass, he never goes out of his way to KickTheDog, and is willing to be friendly with Jacob until the warden requests he be detained. [[spoiler:He only really starts getting aggressive with Lee after things have gone to hell, and considering how Jacob sent a pack of biophages at him as a distraction, this isunderstandable]].understandable]].
** He's also not a member of [[spoiler: Kallipolis[=/=]The Circle, unlike Warden Cole or Dr. Mahler]], and is caught completely unaware just like the rest of the guards when [[spoiler: Cole activates the Callisto Protocol]].
** While he is certainly an ass, he never goes out of his way to KickTheDog, and is willing to be friendly with Jacob until the warden requests he be detained. [[spoiler:He only really starts getting aggressive with Lee after things have gone to hell, and considering how Jacob sent a pack of biophages at him as a distraction, this is
** He's also not a member of [[spoiler: Kallipolis[=/=]The Circle, unlike Warden Cole or Dr. Mahler]], and is caught completely unaware just like the rest of the guards when [[spoiler: Cole activates the Callisto Protocol]].
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* CutscenePowerToTheMax: When Jacob sends a group of Biophages against him, he kills one with a single baton strike and another with a single [=GRP=] throw into a regular wall (rather than spikes or a TurbineBlender); Jacob can't OneHitKill Biophages like that even with max upgrades on easy difficulty. Also crosses into CutsceneIncompetence when the 3rd Biophage seemingly kills him with a single tackle over a ledge.
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* GiantSpaceFleaFromNowhere: She has no plot-related reason to mutate into a giant super-Biophage, and just exists to close out the series on a FinalExamBoss fight that seems designed to encompass the game's whole combat system better than the Ferris boss fight from the end of the main game.
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* GiantSpaceFleaFromNowhere: She has no plot-related reason to mutate into a giant super-Biophage, and her doing so is AllJustADream anyway, so she seems to just exists exist to close out the series on a FinalExamBoss fight that seems designed to encompass the game's whole combat system better than the Ferris boss fight from the end of the main game.
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* GiantSpaceFleaFromNowhere: She has no plot-related reason to mutate into a giant super-Biophage, and just exists to close out the series on a FinalExamBoss fight that seems designed to encompass the game's whole combat system better than the Ferris boss fight from the end of the main game.
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* AreaOfEffect: They can overcharge and release a burst of electricity, damaging you if you're standing too close. This attack can be blocked, but only if you're not committed to a combo chain. This both makes the block move somewhat useful (there was no point using it in the main game) and also encourages the player to not just mash the attack button during the fight.
* ComboBreaker: She has an undodgeable ground slam attack to break your combat flow, so you can't always just wait to dodge her attacks then counterattack and will have to be aggressive at some points in melee.
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* FinalExamBoss: Defeating her involves a mix of melee and ranged combat, as she uses both melee and ranged attacks and is only vulnerable to melee damage when in melee mode and ranged damage when in ranged mode. Saw blades and explosive cannisters are also scattered around the arena which can be thrown at her with the [=GRP=] to damage her in either mode.
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* FinalExamBoss: Defeating her involves a mix of melee and ranged combat, as she uses both melee and ranged attacks and is only vulnerable to melee damage when in melee mode and ranged damage when in ranged mode. Additionally, she has an undodgeable ground slam attack, which forces you to be aggressive at some points in melee and not just rely on the usual dodge-counterattack crutch you've used the entire game. Saw blades and explosive cannisters are also scattered around the arena which can be thrown at her with the [=GRP=] to damage her in either mode.
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* ContractualBossImmunity: He's too large to be [=GRP=]'d, and you can't do melee combos on him as he won't be staggered and will just clobber you after the first hit.
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* ContractualBossImmunity: He's too large to be [=GRP=]'d, and you can't do melee combos on him as he won't be staggered and will just clobber you after the first hit. He also can't be stealth-killed.
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* ContractualBossImmunity: Like the Two-Head and Ferris, she can't be [=GRP=]'d.
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[[folder:The Final Biophage '''(Unmarked Spoilers)''']]
!!Dr. Caitlyn Mahler
A Biophage-mutated Dr. Mahler serves as the FinalBoss of the ''Final Transmission'' DLC and the ''Callisto Protocol'' storyline as a whole, transforming into a powerful and unique Biophage mutant after being infected and thrown down a garbage incinerator by a Big Mouth. Jacob Lee fights her in one final battle before finally departing Callisto once and for all.
* AllYourPowersCombined: She has the size and raw strength of the Two-Head combined with a spit attack similar to the Big Mouth's.
* AttackItsWeakPoint: When in her ranged combat mode, she'll have a glowing red weak spot in her open chest which is the only means of damaging her.
* FinalExamBoss: Defeating her involves a mix of melee and ranged combat, as she uses both melee and ranged attacks and is only vulnerable to melee damage when in melee mode and ranged damage when in ranged mode. Saw blades and explosive cannisters are also scattered around the arena which can be thrown at her with the [=GRP=] to damage her in either mode.
* TeleportSpam: She'll teleport around between spit attacks in her ranged combat mode, exhibiting an ability which breaks the laws of physics ''much'' more than anything else demonstrated by any other Biophage. This is a hint that the events of the [=DLC=] are AllJustADream.
[[/folder]]
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* FlunkyBoss: Ferris' final form isn't ''too'' overwhelming (his melee strike, while powerful, can be dodged just like any other, and his projectile attacks don't do too much damage and can also be avoided), but the big challenge in the fight comes from the fact that constantly respawning Combustors will keep trying to suicide bomb you while you're busying fighting him.
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* FlunkyBoss: Ferris' final form isn't ''too'' overwhelming (his melee strike, while extremely powerful, can be dodged just like any other, and his projectile attacks don't do too much damage and can also be avoided), but the big challenge in the fight comes from the fact that constantly respawning Combustors will keep trying to suicide bomb you while you're busying fighting him.
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* ImmuneToBullets: Played straight in his first form. Jacob's ranged attacks only briefly daze him at best, but mostly just piss him off. This extends to gameplay as well, as he isn't staggered by gunfire like regular Biophages are. Even in his second form only his head is vulnerable, and he covers it with a fleshy armor dome that needs to be shot off.
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* ImmuneToBullets: Played straight in his first form. Jacob's ranged attacks only briefly daze him at best, but mostly just piss him off. This extends to gameplay as well, as well; he isn't staggered by gunfire like regular Biophages are. are, and he's also ''extremely'' resistant to bullet damage, requiring over 100 rounds of fully upgraded assault rifle fire to end the fight both times you fight him (whereas if you stick to melee attacks he's only got about 3 times the health of a regular Biophage). Even in his second form (which can ''only'' be defeated with firearms or explosives) only his head is vulnerable, and he covers it with a fleshy armor dome that needs to be shot off.
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* KingMook: In his first form, he has a few unique advantages (besides the ContractualBossImmunity and ImmuneToBullets already mentioned, he also has a really long combo string of several punches instead of just 2 or 3 like other Biophages), but otherwise fighting him is just like fighting any other Biophage in melee combat.
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* TheGoomba: Early on, standard Grunts have reduced health and can't mutate. After the first few chapters once you get a full equipment loadout, the Grunts become tougher and start being more on par with other Biophage types in terms of durability.
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* StoneWall: They can take ''a lot'' of hits, having several times as much health as a regular Grunt and requiring over 40 rounds of assault rifle fire to bring down. They can also be very fast when they want to, but surprisingly their attacks don't do much damage despite how huge and powerful they appear.
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* StoneWall: They can take ''a lot'' of hits, having several times as much health as a regular Grunt and requiring over 40 rounds of fully upgraded assault rifle fire to bring down. They can also be very fast when they want to, but surprisingly their attacks don't do much damage despite how huge and powerful they appear.
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* FlunkyBoss: Ferris' final form isn't ''too'' overwhelming (his melee strike, while powerful, can be dodged just like any other, and his projectile attacks don't do too much damage and can also be avoided), but the big challenge in the fight comes from the fact that constantly respawning Combustors will keep trying to suicide bomb you while you're busying fighting him.
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* DegradedBoss: The first two you encounter are treated like MiniBoss battles; the first you're encouraged to stealth around, while the second one is a mandatory fight. Later in the game you encounter them in larger numbers and have to find a kinetic hammer to be able to fight them in groups.
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* DegradedBoss: The first two you encounter are treated like MiniBoss battles; the first you're encouraged to stealth around, while the second one is a mandatory fight.fight and also has more health than normal. Later in the game you encounter them in larger numbers and have to find a kinetic hammer to be able to fight them in groups.
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* GlassCannon: Their health is average (though the fact they run away alot means landing consecutive melee strikes on them is very difficult), but they hit ''hard'' and can take off well over half your total health in just 1 hit.
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* EliteMooks: They hit very hard and are extremely resilient themselves. Engaging them in a straight fight is more trouble than it's worth, so it's better to sneak around them.
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* EliteMooks: They hit very hard and are extremely resilient themselves. Engaging them in a straight fight is more trouble than it's worth, especially given they tend to appear in large groups, so it's better to sneak around them.
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[[folder:Biobot]]
A new enemy that appears in the "Final Transmission" DLC. Appears to be a Security Robot that has had many of its parts replaced with biophage-infected organic components.
* AndIMustScream: The data logs you find indicate that by integrating the infected subjects into a security robot, Mahler was partially successful in averting the homicidal insanity of biophage transformation. However, being turned into a cyborg and with no clear purpose in life remaining, the subjects would grow increasingly insane and aggressive anyway. [[spoiler: This is a foreshadowing of Jacob's own situation as human remains hooked up to a life support machine; Mahler is having him go through "one last mission" in his mind to help maintain his sanity while she transmits her data through his brain chip.]]
* DegradedBoss: The first two you encounter are treated like MiniBoss battles; the first you're encouraged to stealth around, while the second one is a mandatory fight. Later in the game you encounter them in larger numbers and have to find a kinetic hammer to be able to fight them in groups.
* MeatSackRobot: The data logs you find indicate they're biophage-infected subjects integrated into a security robot chassis.
* StoneWall: They can take ''a lot'' of hits, having several times as much health as a regular Grunt and requiring over 40 rounds of assault rifle fire to bring down. They can also be very fast when they want to, but surprisingly their attacks don't do much damage despite how huge and powerful they appear.
[[/folder]]
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* TheAtoner: Despite having mitigating circumstances to his crimes and wanting to break out of the HellholePrison he's stuck in, he does believe that he still needs to make up for what he's done. It's indicated to be why he's so friendly, helpful and generally pleasant to be around.
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* NiceGuy: Friendly, considerate, and extremely helpful. It's indicated to be a deliberate way of being TheAtoner for his past crimes.
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* SheepInSheepsClothing: He comes across as oddly friendly and helpful for an inmate in a maximum-security prison, even taking into account the alien ZombieApocalypse that's forcing him and Jacob to work together to survive. Not only that, but there's a string of odd coincidences as you follow his instructions that make Jacob (and potentially the player) begin to suspect that he's just using him as a disposable patsy to help with his own escape. None of it is true, though - he's TheAtoner and a sincere NiceGuy who's doing his best in a difficult, chaotic situation.
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* SecretKeeper: [[spoiler:Jacob knew he and Max weren't just delivering medical caches to the colonies when he found one of the canisters holding the Biophage Pathogen (though he didn't know what it was) under the supplies. Instead of saying something when Max asks what he found, Jacob, [[OnlyInItForTheMoney who only cares about the big payout for their supply runs]], brushes it off and says it's none of their business]].
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* FaceDeathWithDignity: [[spoiler:After sending Leon's memories into space to help Dani take down Cole and Kallipolis, she seems at peace and makes no effort to try and escape Black Iron, only looking upwards as the ceiling finally collapses upon her]].
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* FaceDeathWithDignity: [[spoiler:After sending Leon's Lee's memories into space to help Dani take down Cole and Kallipolis, she seems at peace and makes no effort to try and escape Black Iron, only looking upwards as the ceiling finally collapses upon her]].
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* FaceDeathWithDignity: [[spoiler:After sending Leon's memories into space to help Dani take down Cole and Kallipolis, she seems at peace and makes no effort to try and escape Black Iron, only looking upwards as the ceiling finally collapses upon her]].
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* DevouredByTheHorde: [[spoiler:The end of the ''Final Transmission'' DLC shows that the horde that attacked him at the end of the game managed to tear him apart, but his head and torso were alive and intact enough for Mahler to extract his memories and send them into space to hopefully corroborate Dani's claims against Ferris and his colleagues]].
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* HeroicSacrifice: [[spoiler:Puts Dani into the sole escape pod and sends her away from the self-destructing Black Iron as he stays behind (though [[SequelHook there is still a chance for him to survive]]).]]
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* HeroicSacrifice: [[spoiler:Puts Dani into the sole escape pod and sends her away from the self-destructing Black Iron as he stays behind (though [[SequelHook there is still behind.]] [[spoiler: While the stinger at the end of the original game makes it look like he has a chance for him to survive]]).survive, the Last Transmission DLC confirms his death at the end.]]
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Fairly mundane.
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* CruelAndUnusualDeath: [[spoiler:Slowly dies via asphyxiation after his suit's visor gets smashed while out on the moon's surface.]]
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* Expy: They are very similar to the Stalkers from Dead Space 2, frequently lurking out of or in brief view before they attempt to tackle you and retreat to cover for another round.
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* Expy: {{Expy}}: They are very similar to the Stalkers from Dead Space 2, frequently lurking out of or in brief view before they attempt to tackle you and retreat to cover for another round.
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* Pre-Asskicking One-Liner: Delivers one in the final fight
"Now, I'm gonna show you"
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* AncientConspiracy: [[spoiler: Is a part of one called the Commonality, which has been trying to guide humanity's development for centuries.]]
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* AncientConspiracy: [[spoiler: Is a part of one called Kallipolis (who have the Commonality, same logo, motto, and ultimate goal as the AncientConspiracy from ''VideoGame/PlayerUnknownsBattlegrounds''), which has been trying to guide humanity's development for centuries.centuries and whose ultimate goal is to create "The Commonality", the next step in human evolution.]]
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* Pre-Asskicking One-Liner: Delivers one in the final fight
"Now, I'm gonna show you"
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* Expy: They are very similar to the Stalkers from Dead Space 2, frequently lurking out of or in brief view before they attempt to tackle you and retreat to cover for another round.
