When you find yourself trying to remember a show (or any works) that's on the tip of your tongue but just out of reach, come here - the collective brain of the TVTropes community can probably help. Post all the details you can remember (examples help). If you're looking for a trope, head over to Trope Finder. Have general questions about tropes? Visit Ask The Tropers!
... You might want to provide a bit more information
But yeah, we need a bit more to go on.
Going off your title and Maso's idea of "slime" referring to the 90's Nick gameshows with slime, could you be looking for Figure It Out?
Edited by Beefcube
It could also be Get Your Own Back, if you were talking about British TV.
TV Tropes's No. 1 bread themed lesbian. she/her, fae/faer
"You Can't Do That on Television"?http://m.imdb.com/title/tt0078714/
If it isn't Figure It Out, The Real Ghostbusters?
Saving the world, one fret button at a time.
What color were the main character's socks?
This could be the most mysterious query ever made on YKTS.
Saving the world, one fret button at a time.
the show with the slime